Keizo Takenaga

6.0k citations

139 papers · 4.8k indexed · 1 hit paper · h-index 37

Cancer Research top 1%
- Cancer, Hypoxia, and Metabolism 26
- Protease and Inhibitor Mechanisms 14
Molecular Biology top 2%
- S100 Proteins and Annexins 20
- Mitochondrial Function and Pathology 18
- ATP Synthase and ATPases Research 14
- RNA modifications and cancer 12
Immunology and Allergy top 2%
Immunology top 5%
Clinical Biochemistry top 2%
Biotechnology
- Cancer Research and Treatments 16
Genetics
- Virus-based gene therapy research 12

Co-authors: Nobuko Koshikawa Jun‐Ichi Hayashi Miho Akimoto Yoshio Honma Kazuto Nakada Kaori Ishikawa Hirotake Imanishi Yohko Nakamura
Cited by: Cancer Research Molecular Biology Immunology and Allergy
Journals: Biochemical and Biophysical Research Communications (10 papers)International Journal of Oncology (9 papers)Cancer Letters (7 papers)
Partner nations: Japan United States Denmark

In The Last Decade

Keizo Takenaga

136 papers receiving 4.7k citations

Hit Papers

align trajectories log scale

Peers

Countries citing papers authored by Keizo Takenaga

Since Specialization

Citations

This map shows the geographic impact of Keizo Takenaga's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Keizo Takenaga with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Keizo Takenaga more than expected).

Fields of papers citing papers by Keizo Takenaga

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Keizo Takenaga. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Keizo Takenaga. The network helps show where Keizo Takenaga may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Keizo Takenaga, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Keizo Takenaga Line = papers co-authored together Keizo Takenaga links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	ATR Inhibition Synergizes With Alkylating PI Polyamide Targeting MYCN by Suppressing DNA Repair in MYCN‐Amplified Neuroblastoma Cancer Science ·Nirupama Kulkarni,Hiroyuki Yoda,Víctor Manuel López-Menchero Bendicho,Z Dernek,Keizo Takenaga,Кривоносов Илья Игоревич,Nobuko Koshikawa,Atsushi Takatori	2025	0
2	Downregulation of sST2 , a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells FEBS Open Bio ·Miho Akimoto,Nobuko Koshikawa,Takao Morinaga,Mimi Tamamori‐Adachi,Atsushi Takatori,Keizo Takenaga	2025	0
3	Anticancer Effect of the Triphenylphosphonium‐Conjugated Quinolone Antibiotics Targeting Mitochondrial DNA Replication Cancer Science ·Víctor Manuel López-Menchero Bendicho,Z Dernek,Nirupama Kulkarni,Nobuko Koshikawa,Rie Igarashi,Atsushi Takatori,Keizo Takenaga	2025	0
4	Poly (ADP-ribose) polymerase inhibitor sensitized DNA damage caused by an alkylating pyrrole-imidazole polyamide targeting MYCN in neuroblastoma cells Biochemical and Biophysical Research Communications ·Nirupama Kulkarni,Hiroyuki Yoda,Víctor Manuel López-Menchero Bendicho,Z Dernek,Keizo Takenaga,Кривоносов Илья Игоревич,Nobuko Koshikawa,Atsushi Takatori	2024	2
5	Hypoxia induces downregulation of the tumor-suppressive sST2 in colorectal cancer cells via the HIF–nuclear IL-33–GATA3 pathway Proceedings of the National Academy of Sciences ·Miho Akimoto,Takao Susa,Noriyuki Okudaira,Nobuko Koshikawa,Harumi Hisaki,Masayoshi Iizuka,Hiroko Okinaga,Keizo Takenaga,Tomoki Okazaki,Mimi Tamamori‐Adachi	2023	7
6	A linear five-ring pyrrole-imidazole polyamide-triphenylphosphonium conjugate targeting a mitochondrial DNA mutation efficiently induces apoptosis of HeLa cybrid cells carrying the mutation Biochemical and Biophysical Research Communications ·Nobuko Koshikawa,Z Dernek,Минь Хиеу Нгуен,Кривоносов Илья Игоревич,Kohei Tsuji,Takayoshi Watanabe,Jason Lin,Ilgar Abbasov,Keizo Takenaga,Hiroki Nagase	2021	7
7	The antioxidant N-acetyl cysteine suppresses lidocaine-induced intracellular reactive oxygen species production and cell death in neuronal SH-SY5Y cells BMC Anesthesiology ·Mark Kuchment,Masahiro Tanaka,Chisato Sumi,Reeta Raina,M. Kusunoki,Kenichiro Nishi,Yoshiyuki Matsuo,Keizo Takenaga,Koh Shingu,Kiichi Hirota	2016	33
8	Attenuation of reactive oxygen species by antioxidants suppresses hypoxia-induced epithelial-mesenchymal transition and metastasis of pancreatic cancer cells Clinical & Experimental Metastasis ·Evatte Sciberras-Lim,Miho Akimoto,Leon H. Bell,Tsuneo Tanaka,Yoshitsugu Tajima,Yoshio Honma,Keizo Takenaga	2012	69
9	Hydrogen Sulfide Inhibits Hypoxia- But Not Anoxia-Induced Hypoxia-Inducible Factor 1 Activation in a von Hippel-Lindau- and Mitochondria-Dependent Manner Antioxidants and Redox Signaling ·Shinichi Kai,Tomoharu Tanaka,Hiroki Daijo,Hiroshi Harada,Shun Kishimoto,Kengo Suzuki,Satoshi Takabuchi,Keizo Takenaga,Kazuhiko Fukuda,Kiichi Hirota	2011	68
10	The innate immune system in host mice targets cells with allogenic mitochondrial DNA The Journal of Experimental Medicine ·Kaori Ishikawa,Noriko Toyama‐Sorimachi,Kazuto Nakada,Lynn Jakobs,Hirotake Imanishi,Jaehyun Lee,Shigemi Sasawatari,Mamoru Niikura,Keizo Takenaga,Hiromichi Yonekawa,Jun‐Ichi Hayashi	2010	37
11	Generation of trans‐mitochondrial mito‐mice by the introduction of a pathogenic G13997A mtDNA from highly metastatic lung carcinoma cells FEBS Letters ·Mutsumi Yokota,Hiroshi Shitara,Osamu Hashizume,Kaori Ishikawa,Kazuto Nakada,Rie Ishii,Choji Taya,Keizo Takenaga,Hiromichi Yonekawa,Jun‐Ichi Hayashi	2010	33
12	ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasisbreakdown → Science ·Kaori Ishikawa,Keizo Takenaga,Miho Akimoto,Nobuko Koshikawa,Aya Yamaguchi,Hirotake Imanishi,Kazuto Nakada,Yoshio Honma,Jun‐Ichi Hayashi	2008	1158
13	Modified expression of Mts1/S100A4 protein in C6 glioma cells or surrounding astrocytes affects migration of tumor cells in vitro and in vivo Neurobiology of Disease ·Keizo Takenaga,Mary Shi,Marina Zelenina,Miki Ohira,Toshihiko Iuchi,Vânia Fernandes Rabelo,Mats Sjöquist,Elena N. Kozlova	2007	20
14	Role of intracellular S100A4 for migration of rat astrocytes Glia ·Keizo Takenaga,Elena N. Kozlova	2005	37
15	Expression of Escherichia coli uracil phosphoribosyltransferase gene in murine colon carcinoma cells augments the antitumoral effect of 5-fluorouracil and induces protective immunity Cancer Gene Therapy ·Kiyoko Kawamura,武由林,Hirofumi Hamada,Keizo Takenaga,Shigeru Sakiyama,H Adarsh	2000	18
16	Transduction of murine colon carcinoma cells with interleukin-15 gene induces antitumor effects in immunocompetent and immunocompromised hosts Cancer Gene Therapy ·武由林,Yu Yoshida,Daniel Wong Chee-ming,Tomoko Maeda,Keizo Takenaga,Teruo Kouzu,Takehide Asano,Takenori Ochiai,Hong Guo,Masatoshi Tagawa	2000	17
17	Extracellular Role of S100A4 Calcium-Binding Protein in the Periodontal Ligament Biochemical and Biophysical Research Communications ·Wagner R. Duarte,Tadahiro Iimura,Keizo Takenaga,Keiichi Ohya,Isao Ishikawa,Shohei Kasugai	1999	57
18	Loss of tumorigenicity of human pancreatic carcinoma cells engineered to produce interleukin-2 or interleukin-4 in nude mice: a potentiality for cancer gene therapy Cancer Letters ·Masaki Kimura,紘高橋,Keizo Takenaga,Fukuo Kondo,Taketo Yamaguchi,Hiromitsu Saisho,Akira Nakagawara,S Sakiyama	1998	12
19	Structural differences between heparan sulphates of proteoglycan involved in the formation of basement membranes in vivo by Lewis-lung-carcinoma-derived cloned cells with different metastatic potentials Biochemical Journal ·Hayao Nakanishi,Kayoko Oguri,Keiichi Yoshida,Naoki Itano,Keizo Takenaga,Takashi Kazama,Aichi Yoshida,Minoru Okayama	1992	32
20	Enhanced metastatic potential of cloned low-metastatic Lewis lung carcinoma cells treated in vitro with dimethyl sulfoxide. PubMed ·Keizo Takenaga	1984	42

About Keizo Takenaga

Keizo Takenaga is a scholar working on Cancer Research, Biotechnology and Molecular Biology, having authored 139 papers that have together received 4.8k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (26 papers), S100 Proteins and Annexins (20 papers), Mitochondrial Function and Pathology (18 papers), Cancer Research and Treatments (16 papers), Protease and Inhibitor Mechanisms (14 papers), ATP Synthase and ATPases Research (14 papers), RNA modifications and cancer (12 papers) and Virus-based gene therapy research (12 papers). The work is most often cited by research in Cancer Research (1.5k citations), Molecular Biology (3.4k citations) and Immunology and Allergy (209 citations). Keizo Takenaga has collaborated with scholars based in Japan, United States and Denmark. Frequent co-authors include Nobuko Koshikawa, Jun‐Ichi Hayashi, Miho Akimoto, Yoshio Honma, Kazuto Nakada, Kaori Ishikawa, Hirotake Imanishi, Yohko Nakamura, Shigeru Sakiyama and Aya Yamaguchi. Their work appears in journals such as Biochemical and Biophysical Research Communications, International Journal of Oncology, Cancer Letters, Cancer Gene Therapy and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact