Kuo‐Hsiung Lee

34.0k citations

772 papers · 28.5k indexed · 1 hit paper · h-index 81

Molecular Biology top 0.1%
Organic Chemistry top 0.05%
Plant Science top 0.2%
Pharmacology top 0.05%
Pharmacology top 0.02%

Co-authors: Susan L. Morris‐Natschke Kenneth F. Bastow Chin‐Ho Chen Keduo Qian L. Mark Cosentino Yoshiki Kashiwada Tian-Shung Wu Zhiyan Xiao
Topics: Natural product bioactivities and synthesis (177 papers)Phytochemical compounds biological activities (101 papers)Traditional and Medicinal Uses of Annonaceae (92 papers)
Cited by: Toxicology Organic Chemistry Pharmacology
Journals: Science Journal of Biological ChemistrySHILAP Revista de lepidopterología
Partner nations: United States Taiwan China

In The Last Decade

Kuo‐Hsiung Lee

750 papers receiving 27.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rational selection of training and test sets for the development of validated QSAR models

2003 568 citations Zhiyan Xiao, Kuo‐Hsiung Lee et al. profile →

Peers

Countries citing papers authored by Kuo‐Hsiung Lee

Since Specialization

Citations

This map shows the geographic impact of Kuo‐Hsiung Lee's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kuo‐Hsiung Lee with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kuo‐Hsiung Lee more than expected).

Fields of papers citing papers by Kuo‐Hsiung Lee

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kuo‐Hsiung Lee. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kuo‐Hsiung Lee. The network helps show where Kuo‐Hsiung Lee may publish in the future.

Co-authorship network of co-authors of Kuo‐Hsiung Lee

This figure shows the co-authorship network connecting the top 25 collaborators of Kuo‐Hsiung Lee. A scholar is included among the top collaborators of Kuo‐Hsiung Lee based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kuo‐Hsiung Lee. Kuo‐Hsiung Lee is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Design, synthesis and structure-activity relationships of 4-phenyl-1H-1,2,3-triazole phenylalanine derivatives as novel HIV-1 capsid inhibitors with promising antiviral activities 2020 ·European Journal of Medicinal Chemistry ·Lin Sun,(unknown),Alexej Dick,Megan E. Meuser,Waleed A. Zalloum,Chin‐Ho Chen,Xiao Ding,Ping Gao,Simon Cocklin,Kuo‐Hsiung Lee,Peng Zhan,Xinyong Liu	92
2	Design, Synthesis, and Mechanism Study of Benzenesulfonamide-Containing Phenylalanine Derivatives as Novel HIV-1 Capsid Inhibitors with Improved Antiviral Activities 2020 ·Journal of Medicinal Chemistry ·Lin Sun,Alexej Dick,Megan E. Meuser,(unknown),Waleed A. Zalloum,Chin‐Ho Chen,Srinivasulu Cherukupalli,Shujing Xu,Xiao Ding,Ping Gao,Dongwei Kang,Erik De Clercq,Christophe Pannecouque,Simon Cocklin,Kuo‐Hsiung Lee,Xinyong Liu,Peng Zhan	46
3	Discovery of potential dual-target prodrugs of HIV-1 reverse transcriptase and nucleocapsid protein 7 2020 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Boshi Huang,Zhuo Li,Zhao Wang,Lin Sun,Ping Gao,Dongwei Kang,Chin‐Ho Chen,Kuo‐Hsiung Lee,Dirk Daelemans,Erik De Clercq,Christophe Pannecouque,Peng Zhan,Xinyong Liu	3
4	Design and Synthesis of Quinolizidine Derivatives as Influenza Virus and HIV-1 Inhibitors 2020 ·Current Medicinal Chemistry ·Zhao Dang,Lei Zhu,Lan Xie,Kuo‐Hsiung Lee,Faisal Malik,Zhijun Li,Li Huang,Chin‐Ho Chen	3
5	Discovery of an Oleanolic Acid/Hederagenin–Nitric Oxide Donor Hybrid as an EGFR Tyrosine Kinase Inhibitor for Non-Small-Cell Lung Cancer 2019 ·Journal of Natural Products ·Zhong Chen,Kuo‐Yen Huang,Yong Ling,Masuo Goto,(unknown),(unknown),Yanli Liu,Yung‐Yi Cheng,Susan L. Morris‐Natschke,Pan‐Chyr Yang,Shilin Yang,Kuo‐Hsiung Lee	41
6	Identification of Dihydrofuro[3,4-d]pyrimidine Derivatives as Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors with Promising Antiviral Activities and Desirable Physicochemical Properties 2019 ·Journal of Medicinal Chemistry ·Dongwei Kang,Heng Zhang,Zhao Wang,Tong Zhao,Tiziana Ginex,F. Javier Luque,Yang Yang,Gaochan Wu,Da Feng,Fenju Wei,Jian Zhang,Erik De Clercq,Christophe Pannecouque,Chin Ho Chen,Kuo‐Hsiung Lee,N. Arul Murugan,Thomas A. Steitz,Peng Zhan,Xinyong Liu	75
7	Ochrocephalamines B–D, Three Alkaloids from Oxytropis ochrocephala Bunge 2019 ·Organic Letters ·(unknown),Ping Yi,Tao Yang,(unknown),Fu‐Mei Yang,Kuo‐Hsiung Lee,Baoyu Zhao,Yue‐Hu Wang,Cheng‐Jian Tan	17
8	Antiproliferative Aspidosperma-Type Monoterpenoid Indole Alkaloids from Bousigonia mekongensis Inhibit Tubulin Polymerization 2019 ·Molecules ·Yu Zhang,Masuo Goto,Akifumi Oda,(unknown),(unknown),Yan-Hui Fu,Susan L. Morris‐Natschke,Ernest Hamel,Kuo‐Hsiung Lee,Xiao‐Jiang Hao	18
9	Discovery of novel 1,4-disubstituted 1,2,3-triazole phenylalanine derivatives as HIV-1 capsid inhibitors 2019 ·RSC Advances ·Xiangyi Jiang,Gaochan Wu,Waleed A. Zalloum,Megan E. Meuser,Alexej Dick,Lin Sun,Chin‐Ho Chen,Dongwei Kang,Lanlan Jing,Ruifang Jia,Simon Cocklin,Kuo‐Hsiung Lee,Xinyong Liu,Peng Zhan	53
10	Design, synthesis, and biologic evaluation of novel galloyl derivatives as HIV‐1 RNase H inhibitors 2018 ·Chemical Biology & Drug Design ·Ping Gao,Xueshun Wang,Lin Sun,(unknown),Vasanthanathan Poongavanam,Jacob Kongsted,Mar Álvarez,Joanna Luczkowiak,Christophe Pannecouque,Erik De Clercq,Kuo‐Hsiung Lee,Chin‐Ho Chen,Huiqing Liu,Luis Menéndez‐Arias,Xinyong Liu,Peng Zhan	13
11	Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities 2018 ·European Journal of Medicinal Chemistry ·Yong Ling,(unknown),Yu‐Ning Teng,Shi Chen,(unknown),Jing Guo,Pei‐Ling Hsu,(unknown),Susan L. Morris‐Natschke,Chin‐Chuan Hung,Kuo‐Hsiung Lee	31
12	SAR study on N²,N⁴-disubstituted pyrimidine-2,4-diamines as effective CDK2/CDK9 inhibitors and antiproliferative agents 2018 ·RSC Advances ·(unknown),(unknown),Masuo Goto,Kuo‐Hsiung Lee,Zhiyan Xiao	13
13	Chemical Structures and Biological Activities of Limonoids from the Genus Swietenia (Meliaceae) 2018 ·Molecules ·(unknown),(unknown),(unknown),Gang Wang,Susan L. Morris‐Natschke,(unknown),(unknown),(unknown),Kuo‐Hsiung Lee	27
14	Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release 2017 ·Free Radical Biology and Medicine ·Guang Xin,Zeliang Wei,Chengjie Ji,(unknown),Jun Gu,Limei Ma,(unknown),(unknown),Susan L. Morris‐Natschke,Jwu‐Lai Yeh,Rui Zhang,Chaoyi Qin,Wen Li,Zhihua Xing,Yu Cao,Qing Xia,Ke Li,Hai Niu,Kuo‐Hsiung Lee,(unknown),(unknown)	39
15	A Novel Plant Sesquiterpene Lactone Derivative, DETD-35, Suppresses BRAFV600E Mutant Melanoma Growth and Overcomes Acquired Vemurafenib Resistance in Mice 2016 ·Molecular Cancer Therapeutics ·(unknown),Kyoko Nakagawa‐Goto,Kuo‐Hsiung Lee,Lie‐Fen Shyur	19
16	Toward synthesis of third-generation spin-labeled podophyllotoxin derivatives using isocyanide multicomponent reactions 2014 ·European Journal of Medicinal Chemistry ·(unknown),(unknown),Li‐Ting Wang,(unknown),Xiang Nan,Yang Liu,Ying-Qian Liu,Susan L. Morris‐Natschke,Kuo‐Hsiung Lee	14
17	Bioactive constituents of Clausena lansium and a method for discrimination of aldose enantiomers 2012 ·Phytochemistry ·De-Yang Shen,Chih‐Hua Chao,Hsiu-Hui Chan,Guan-Jhong Huang,Tsong‐Long Hwang,Chin-Yu Lai,Kuo‐Hsiung Lee,Trân Đình Thăng,Tian-Shung Wu	47
18	Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters 2005 ·Bioorganic & Medicinal Chemistry ·Seikou Nakamura,Mutsuo Kozuka,Kenneth F. Bastow,Harukuni Tokuda,Hoyoku Nishino,Madoka Suzuki,(unknown),(unknown),Sheng-Chu Kuo,Kuo‐Hsiung Lee	48
19	Research and Discovery Trends of Chinese Medicine in the New Century 2004 ·Kuo‐Hsiung Lee	8
20	Tannins as Potent Inhibitors of DNA Topoisomerase II In Vitro 1993 ·Journal of Pharmaceutical Sciences ·Yoshiki Kashiwada,Gen‐ichiro Nonaka,Itsuo Nishioka,(unknown),(unknown),Ibrahim D. Bori,(unknown),Kenneth F. Bastow,Kuo‐Hsiung Lee	82

About Kuo‐Hsiung Lee

Kuo‐Hsiung Lee is a scholar working on Toxicology, Biochemistry and Virology, having authored 772 papers that have together received 28.5k indexed citations. Recurring topics across this work include Natural product bioactivities and synthesis (177 papers), Phytochemical compounds biological activities (101 papers) and Traditional and Medicinal Uses of Annonaceae (92 papers). The work is most often cited by research in Toxicology (1.9k citations), Organic Chemistry (9.8k citations) and Pharmacology (2.8k citations). Kuo‐Hsiung Lee has collaborated with scholars based in United States, Taiwan and China. Frequent co-authors include Susan L. Morris‐Natschke, Kenneth F. Bastow, Chin‐Ho Chen, Keduo Qian, L. Mark Cosentino, Yoshiki Kashiwada, Tian-Shung Wu, Zhiyan Xiao, Lan Xie and Kyoko Nakagawa‐Goto. Their work appears in journals such as Science, Journal of Biological Chemistry and SHILAP Revista de lepidopterología.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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