Mark Cushman

4.2k citations

120 papers · 3.5k indexed · h-index 35

Impact in

Geriatrics and Gerontology top 1%
- Sirtuins and Resveratrol in Medicine
Virology top 2%
- HIV Research and Treatment

Papers in

Virology 13
- HIV Research and Treatment 13
Infectious Diseases 33
- HIV/AIDS drug development and treatment 27

Co-authors: Adelbert Bacher Markus Fischer Dhanapalan Nagarathnam Robert L. Geahlen Kshitij Thakkar Boris Illarionov Erik De Clercq Robert W. Buckheit
Journals: The Journal of Organic Chemistry (31 papers)Journal of Medicinal Chemistry (21 papers)Bioorganic & Medicinal Chemistry (11 papers)Bioorganic & Medicinal Chemistry Letters (10 papers)Tetrahedron Letters (6 papers)
Partner nations: United States Germany Belgium

In The Last Decade

Mark Cushman

119 papers receiving 3.5k citations

Peers

Countries citing papers authored by Mark Cushman

Since Specialization

Citations

This map shows the geographic impact of Mark Cushman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Cushman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Cushman more than expected).

Fields of papers citing papers by Mark Cushman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Cushman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Cushman. The network helps show where Mark Cushman may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Mark Cushman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Mark Cushman Line = papers co-authored together Mark Cushman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Systematic evaluation of methyl ester bioisosteres in the context of developing alkenyldiarylmethanes (ADAMs) as non-nucleoside reverse transcriptase inhibitors (NNRTIs) for anti-HIV-1 chemotherapy Bioorganic & Medicinal Chemistry ·Adn Jacomo, Takeshi Sakamoto, Jun Takayama, S. T. Allworth, Mari Okazaki, Tracy L. Hartman, Robert W. Buckheit, Christophe Pannecouque, Mark Cushman	2016	7
2	Antibacterial Evaluation of Synthetic Thiazole Compounds In Vitro and In Vivo in a Methicillin-Resistant Staphylococcus aureus (MRSA) Skin Infection Mouse Model PLoS ONE ·Haroon Mohammad, Mark Cushman, Mohamed N. Seleem	2015	40
3	Synthesis of 3-(3-aryl-pyrrolidin-1-yl)-5-aryl-1,2,4-triazines that have antibacterial activity and also inhibit inorganic pyrophosphatase Bioorganic & Medicinal Chemistry ·Wei Lv, Biplab Banerjee, Muhammad Amama, Mohamed N. Seleem, I. A. Gritsenko, Maha I. Hamed, Baojie Wan, Scott G. Franzblau, Andrew D. Mesecar, Mark Cushman	2013	31
4	Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets Bioorganic & Medicinal Chemistry ·Abdelrahman S. Mayhoub, Laura E. Marler, Tamara P. Kondratyuk, Eun‐Jung Park, John M. Pezzuto, Mark Cushman	2011	59
5	Structural study and thermodynamic characterization of inhibitor binding to lumazine synthase fromBacillus anthracis Acta Crystallographica Section D Biological Crystallography ·Ekaterina Morgunova, Boris Illarionov, EA McKenzie, H. Ross Payne, Thota Sambaiah, Adelbert Bacher, Mark Cushman, Markus Fischer, Rudolf Ladenstein	2010	16
6	Synthesis of alkenyldiarylmethanes (ADAMs) containing benzo[d]isoxazole and oxazolidin-2-one rings, a new series of potent non-nucleoside HIV-1 reverse transcriptase inhibitors European Journal of Medicinal Chemistry ·Bo‐Liang Deng, Yujie Zhao, Tracy L. Hartman, Karen Watson, Robert W. Buckheit, Christophe Pannecouque, Erik De Clercq, Mark Cushman	2008	28
7	Structural and thermodynamic insights into the binding mode of five novel inhibitors of lumazine synthase from Mycobacterium tuberculosis FEBS Journal ·Ekaterina Morgunova, Boris Illarionov, Thota Sambaiah, Ilka Haase, Adelbert Bacher, Mark Cushman, Markus Fischer, Rudolf Ladenstein	2006	32
8	Synthesis and anti-HIV activity of new alkenyldiarylmethane (ADAM) non-nucleoside reverse transcriptase inhibitors (NNRTIs) incorporating benzoxazolone and benzisoxazole rings Bioorganic & Medicinal Chemistry ·Bo‐Liang Deng, Matthew D. Cullen, Zhigang Zhou, Tracy L. Hartman, Robert W. Buckheit, Christophe Pannecouque, Erik De Clercq, Phillip E. Fanwick, Mark Cushman	2005	77
9	Crystal Structure of an Archaeal Pentameric Riboflavin Synthase in Complex with a Substrate Analog Inhibitor Journal of Biological Chemistry ·E. Rehorn, Martin Augustin, T. K. Henthorn, S. Gerhardt, T. Krojer, Wolfgang Eisenreich, Boris Illarionov, Mark Cushman, Adelbert Bacher, Robert Huber, Markus Fischer	2005	26
10	Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments BMC Biochemistry ·Markus Fischer, T. K. Henthorn, Kristina Kemter, Richard Feicht, Gerald Richter, Boris Illarionov, Wolfgang Eisenreich, S. Gerhardt, Mark Cushman, Stefan Steinbacher, Robert Huber, Adelbert Bacher	2003	16
11	The ‘apparent’ hydrolysis of alkyl esters during electrospray ionization Rapid Communications in Mass Spectrometry ·Emanuel Jeremías Fernández Mazzucco, ŁUKASZ PIERON, Arlene P. Rothwell, Karl V. Wood, Mark Cushman	2003	10
12	Enzyme Catalysis via Control of Activation Entropy: Site-directed Mutagenesis of 6,7-Dimethyl-8-ribityllumazine Synthase Journal of Molecular Biology ·Markus Fischer, Ilka Haase, Klaus Kis, Winfried Meining, Rudolf Ladenstein, Mark Cushman, Nicholas Schramek, Robert Huber, Adelbert Bacher	2003	36
13	Synthesis of alkenyldiarylmethane (ADAM) non-Nucleoside HIV-1 reverse transcriptase inhibitors with non-Identical aromatic rings Bioorganic & Medicinal Chemistry ·Guozhang Xu, Tracy L. Hartman, Christine Birkett, Jim A. Turpin, Robert W. Buckheit, Mark Cushman	2002	17
14	The Structural Basis of Riboflavin Binding to Schizosaccharomyces pombe 6,7-Dimethyl-8-ribityllumazine Synthase Journal of Molecular Biology ·S. Gerhardt, Ilka Haase, Stefan Steinbacher, Jens T. Kaiser, Mark Cushman, Adelbert Bacher, Robert Huber, Markus Fischer	2002	61
15	Domain structure of riboflavin synthase European Journal of Biochemistry ·Sabine Eberhardt, Nora Zingler, Kristina Kemter, Gerald Richter, Mark Cushman, Adelbert Bacher	2001	23
16	Inhibition of RANTES/CCR1-mediated chemotaxis by cosalane and related compounds Bioorganic & Medicinal Chemistry Letters ·O. M. Zack Howard, Hui Dong, Joost J. Oppenheim, P. GLANELLO, Sanjiwani Kumar, Marina Pereira Queiroz dos Santos, Mark Cushman	2001	4
17	Novel Modifications in the Alkenyldiarylmethane (ADAM) Series of Non-Nucleoside Reverse Transcriptase Inhibitors Journal of Medicinal Chemistry ·Agustin Casimiro‐Garcia, Thais García Rodríguez, Jim A. Turpin, F.J.M. Reurs, Karen Watson, Robert W. Buckheit, Mark Cushman	1999	37
18	Synthesis and evaluation of a series of benzylaniline hydrochlorides as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerization Journal of Medicinal Chemistry ·Mark Cushman, M.W. Smit, Chii M. Lin, Ernest Hamel	1993	52
19	Synthesis and protein-tyrosine kinase inhibitory activity of polyhydroxylated stilbene analogs of piceatannol Journal of Medicinal Chemistry ·Kshitij Thakkar, Robert L. Geahlen, Mark Cushman	1993	132
20	Synthesis and Evaluation of Hydroxylated Flavones and Related Compounds as Potential Inhibitors of the Protein-Tyrosine Kinase P56^lck Journal of Natural Products ·Mark Cushman, Dhanapalan Nagarathnam, Robert L. Geahlen	1991	33

About Mark Cushman

Mark Cushman is a scholar working on Virology, Infectious Diseases, Organic Chemistry, Geriatrics and Gerontology and Clinical Biochemistry, having authored 120 papers that have together received 3.5k indexed citations. Recurring topics across this work include Biochemical and Molecular Research (40 papers), Enzyme Structure and Function (33 papers), HIV/AIDS drug development and treatment (27 papers), HIV Research and Treatment (13 papers), Folate and B Vitamins Research (13 papers), Carbohydrate Chemistry and Synthesis (11 papers), Chemical Synthesis and Analysis (10 papers) and Metabolism and Genetic Disorders (9 papers). The work is most often cited by research in Geriatrics and Gerontology (258 citations), Virology (242 citations), Organic Chemistry (1.3k citations), Toxicology (135 citations) and Pharmacology (463 citations). Mark Cushman has collaborated with scholars based in United States, Germany and Belgium. Frequent co-authors include Adelbert Bacher, Markus Fischer, Dhanapalan Nagarathnam, Robert L. Geahlen, Kshitij Thakkar, Boris Illarionov, Erik De Clercq, Robert W. Buckheit, Rudolf Ladenstein and John M. Pezzuto. Their work appears in journals such as The Journal of Organic Chemistry, Journal of Medicinal Chemistry, Bioorganic & Medicinal Chemistry, Bioorganic & Medicinal Chemistry Letters and Tetrahedron Letters.

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