Mark Cushman

9.8k total citations
215 papers, 8.5k citations indexed

About

Mark Cushman is a scholar working on Molecular Biology, Organic Chemistry and Toxicology. According to data from OpenAlex, Mark Cushman has authored 215 papers receiving a total of 8.5k indexed citations (citations by other indexed papers that have themselves been cited), including 143 papers in Molecular Biology, 96 papers in Organic Chemistry and 64 papers in Toxicology. Recurrent topics in Mark Cushman's work include Cancer therapeutics and mechanisms (84 papers), Bioactive Compounds and Antitumor Agents (64 papers) and Synthesis and biological activity (32 papers). Mark Cushman is often cited by papers focused on Cancer therapeutics and mechanisms (84 papers), Bioactive Compounds and Antitumor Agents (64 papers) and Synthesis and biological activity (32 papers). Mark Cushman collaborates with scholars based in United States, China and Germany. Mark Cushman's co-authors include Yves Pommier, Smitha Antony, Glenda Kohlhagen, Andrew Morrell, Ernest Hamel, Keli Agama, Xiangshu Xiao, Dhanapalan Nagarathnam, Bart L. Staker and Lance Stewart and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Clinical Oncology and The Journal of Immunology.

In The Last Decade

Mark Cushman

214 papers receiving 8.3k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mark Cushman United States	53	4.8k	4.5k	1.6k	1.2k	959	215	8.5k
Kenneth F. Bastow United States	49	3.5k 0.7×	3.4k 0.8×	643 0.4×	575 0.5×	1.2k 1.3×	188	7.5k
J. William Lown Canada	48	4.7k 1.0×	3.0k 0.7×	864 0.6×	1.0k 0.8×	476 0.5×	307	8.0k
Mansukh C. Wani United States	45	5.6k 1.2×	1.7k 0.4×	1.2k 0.8×	2.0k 1.6×	1.7k 1.7×	134	8.2k
Giuseppe Bifulco Italy	50	3.9k 0.8×	3.3k 0.7×	396 0.3×	828 0.7×	1.8k 1.9×	277	8.7k
Francis Johnson United States	42	4.5k 0.9×	2.3k 0.5×	236 0.2×	628 0.5×	402 0.4×	236	7.6k
HIROSHI NAGANAWA Japan	46	4.1k 0.9×	3.0k 0.7×	373 0.2×	958 0.8×	3.0k 3.1×	328	7.8k
George A. Ellestad United States	41	3.0k 0.6×	2.4k 0.5×	270 0.2×	630 0.5×	1.1k 1.1×	115	5.8k
Melinda G. Hollingshead United States	45	3.9k 0.8×	1.1k 0.2×	277 0.2×	1.9k 1.5×	385 0.4×	167	6.9k
John L. Nitiss United States	41	6.5k 1.4×	1.3k 0.3×	1.2k 0.8×	2.5k 2.1×	511 0.5×	101	7.4k
Maurizio Botta Italy	54	5.5k 1.1×	5.7k 1.3×	189 0.1×	1.1k 0.9×	971 1.0×	436	11.9k

Countries citing papers authored by Mark Cushman

Since Specialization

Citations

This map shows the geographic impact of Mark Cushman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Cushman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Cushman more than expected).

Fields of papers citing papers by Mark Cushman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Cushman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Cushman. The network helps show where Mark Cushman may publish in the future.

Co-authorship network of co-authors of Mark Cushman

This figure shows the co-authorship network connecting the top 25 collaborators of Mark Cushman. A scholar is included among the top collaborators of Mark Cushman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark Cushman. Mark Cushman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Yang, Danzhou, et al.. (2023). Abstract 3103: Dual targeting MYC G-quadruplex and topoisomerase I by indenoisoquinolines for cancer therapy. Cancer Research. 83(7_Supplement). 3103–3103.

Reguera, Rosa M., et al.. (2019). Antiparasitic effect of synthetic aromathecins on Leishmania infantum. BMC Veterinary Research. 15(1). 405–405. 2 indexed citations

Álvarez‐Velilla, Raquel, Rosa M. Reguera, Carlos García‐Estrada, et al.. (2019). Topoisomerase IB poisons induce histone H2A phosphorylation as a response to DNA damage in Leishmania infantum. International Journal for Parasitology Drugs and Drug Resistance. 11. 39–48. 6 indexed citations

Marzi, Laetitia, Keli Agama, Junko Murai, et al.. (2018). Novel Fluoroindenoisoquinoline Non-Camptothecin Topoisomerase I Inhibitors. Molecular Cancer Therapeutics. 17(8). 1694–1704. 32 indexed citations

Skaar, Todd C., et al.. (2016). A new Suzuki synthesis of triphenylethylenes that inhibit aromatase and bind to estrogen receptors α and β. Bioorganic & Medicinal Chemistry. 24(21). 5400–5409. 19 indexed citations

Lv, Wei, Monica Abdelmalak, Keli Agama, et al.. (2016). Synthesis and biological evaluation of new fluorinated and chlorinated indenoisoquinoline topoisomerase I poisons. Bioorganic & Medicinal Chemistry. 24(7). 1469–1479. 25 indexed citations

Mohammad, Haroon, Abdelrahman S. Mayhoub, Mark Cushman, & Mohamed N. Seleem. (2014). Anti-biofilm activity and synergism of novel thiazole compounds with glycopeptide antibiotics against multidrug-resistant Staphylococci. The Journal of Antibiotics. 68(4). 259–266. 80 indexed citations

Park, Eun‐Jung, Tamara P. Kondratyuk, Andrew Morrell, et al.. (2011). Induction of Retinoid X Receptor Activity and Consequent Upregulation of p21WAF1/CIP1 by Indenoisoquinolines in MCF7 Cells. Cancer Prevention Research. 4(4). 592–607. 30 indexed citations

Sun, Bin, et al.. (2010). Design, synthesis, and biological evaluation of resveratrol analogues as aromatase and quinone reductase 2 inhibitors for chemoprevention of cancer. Bioorganic & Medicinal Chemistry. 18(14). 5352–5366. 71 indexed citations

10.

Cinelli, Maris A., Andrew Morrell, Thomas S. Dexheimer, et al.. (2010). The structure–activity relationships of A-ring-substituted aromathecin topoisomerase I inhibitors strongly support a camptothecin-like binding mode. Bioorganic & Medicinal Chemistry. 18(15). 5535–5552. 19 indexed citations

11.

Pommier, Yves, Smitha Antony, Ze‐Hong Miao, et al.. (2007). Novel indenoisoquinolines NSC 725776 and NSC 724998 produce persistent topoisomerase I cleavage complexes and overcome multidrug resistance. Molecular Cancer Therapeutics. 6. 1 indexed citations

12.

Antony, Smitha, Keli Agama, Ze‐Hong Miao, et al.. (2007). Novel Indenoisoquinolines NSC 725776 and NSC 724998 Produce Persistent Topoisomerase I Cleavage Complexes and Overcome Multidrug Resistance. Cancer Research. 67(21). 10397–10405. 113 indexed citations

13.

Cuendet, Muriel, et al.. (2006). Synthesis and Cancer Chemopreventive Activity of Zapotin, a Natural Product from Casimiroa edulis. Journal of Medicinal Chemistry. 50(2). 350–355. 30 indexed citations

14.

Xiao, Xiangshu, Smitha Antony, Yves Pommier, & Mark Cushman. (2006). Total Synthesis and Biological Evaluation of 22-Hydroxyacuminatine. Journal of Medicinal Chemistry. 49(4). 1408–1412. 50 indexed citations

15.

Antony, Smitha, Keli Agama, Ze‐Hong Miao, et al.. (2006). Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity. Molecular Pharmacology. 70(3). 1109–1120. 33 indexed citations

16.

Xiao, Xiangshu, Ze-Hong Miao, Smitha Antony, Yves Pommier, & Mark Cushman. (2005). Dihydroindenoisoquinolines function as prodrugs of indenoisoquinolines. Bioorganic & Medicinal Chemistry Letters. 15(11). 2795–2798. 27 indexed citations

17.

Sheta, Razan, et al.. (2002). Intestinal absorption and biodistribution of cosalane and its amino acid conjugates: novel anti-HIV agents. International Journal of Pharmaceutics. 231(2). 197–211. 3 indexed citations

18.

Kohlhagen, Glenda, Kenneth D. Paull, Mark Cushman, Pamela Nagafuji, & Yves Pommier. (1998). Protein-Linked DNA Strand Breaks Induced by NSC 314622, a Novel Noncamptothecin Topoisomerase I Poison. Molecular Pharmacology. 54(1). 50–58. 150 indexed citations

19.

Cushman, Mark & Jyothis Mathew. (1982). ChemInform Abstract: NOVEL SYNTHESIS OF THE TETRACYCLIC RING SYSTEM PRESENT IN STREPTONIGRIN. Chemischer Informationsdienst. 13(16). 3 indexed citations

20.

Büchi, G., Mark Cushman, & Hans Wüest. (1974). Conversion of allylic alcohols to homologous amides by N,N-dimethylformamide acetals. Journal of the American Chemical Society. 96(17). 5563–5565. 45 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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