Margaret A. Holmes

5.5k citations

21 papers · 3.8k indexed · 2 hit papers · h-index 15

Molecular Biology top 10%
Immunology top 2%
Nephrology top 1%
Hematology top 2%
Epidemiology top 5%

Co-authors: Roland K. Strong Trude Helen Flo David Rodríguez Kelly D. Smith Alan Aderem Shintaro Sato Shizuo Akira Kenneth N. Raymond
Topics: Monoclonal and Polyclonal Antibodies Research (6 papers)Enzyme Structure and Function (5 papers)Glycosylation and Glycoproteins Research (4 papers)
Cited by: Nephrology Immunology Hematology
Journals: Nature Proceedings of the National Academy of Sciences Journal of Biological Chemistry
Partner nations: United States South Africa Portugal

In The Last Decade

Margaret A. Holmes

21 papers receiving 3.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating iron

2004 1.4k citations Trude Helen Flo, Kelly D. Smith et al. Nature profile →
The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisition

2002 1.1k citations David H. Goetz, Margaret A. Holmes et al. Molecular Cell profile →

Peers

Countries citing papers authored by Margaret A. Holmes

Since Specialization

Citations

This map shows the geographic impact of Margaret A. Holmes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margaret A. Holmes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margaret A. Holmes more than expected).

Fields of papers citing papers by Margaret A. Holmes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margaret A. Holmes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margaret A. Holmes. The network helps show where Margaret A. Holmes may publish in the future.

Co-authorship network of co-authors of Margaret A. Holmes

This figure shows the co-authorship network connecting the top 25 collaborators of Margaret A. Holmes. A scholar is included among the top collaborators of Margaret A. Holmes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Margaret A. Holmes. Margaret A. Holmes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Ontogeny of Recognition Specificity and Functionality for the Broadly Neutralizing Anti-HIV Antibody 4E10 2014 ·PLoS Pathogens ·Kathryn A. K. Finton,Della Friend,(unknown),Mesfin Gewe,Margaret A. Holmes,H. Benjamin Larman,Andrew B. Stuart,Kevin Larimore,Philip D. Greenberg,Stephen J. Elledge,Leonidas Stamatatos,Roland K. Strong	18
2	Siderocalin/Lcn2/NGAL/24p3 Does Not Drive Apoptosis Through Gentisic Acid Mediated Iron Withdrawal in Hematopoietic Cell Lines 2012 ·PLoS ONE ·Colin Correnti,Věra Richardson,(unknown),Ashok D. Bandaranayake,Mario Ruiz,Yohan Suryo Rahmanto,Žaklina Kovačević,Matthew C. Clifton,Margaret A. Holmes,Brett K. Kaiser,Jonathan Barasch,Kenneth N. Raymond,Des R. Richardson,Roland K. Strong	40
3	High‐resolution structure prediction of a circular permutation loop 2011 ·Protein Science ·Bruno E. Correia,Margaret A. Holmes,Po‐Ssu Huang,Roland K. Strong,William R. Schief	5
4	Crystal structure of a γδ T-cell receptor specific for the human MHC class I homolog MICA 2011 ·Proceedings of the National Academy of Sciences ·Bin Xu,J.C. Pizarro,Margaret A. Holmes,Christine McBeth,Veronika Groh,Thomas A. Spies,Roland K. Strong	126
5	Computational Design of Epitope-Scaffolds Allows Induction of Antibodies Specific for a Poorly Immunogenic HIV Vaccine Epitope 2010 ·Structure ·Bruno E. Correia,(unknown),Margaret A. Holmes,Hengyu Xu,(unknown),Zane Kraft,Chris Carrico,Erica Boni,D. Noah Sather,Camille Zenobia,(unknown),(unknown),(unknown),Oleksandr Kalyuzhniy,David Baker,Roland K. Strong,Leonidas Stamatatos,William R. Schief	161
6	Interactions between Lipids and Human Anti-HIV Antibody 4E10 Can Be Reduced without Ablating Neutralizing Activity 2009 ·Journal of Virology ·Hengyu Xu,Likai Song,Mikyung Kim,Margaret A. Holmes,Zane Kraft,George Sellhorn,Ellis L. Reinherz,Leonidas Stamatatos,Roland K. Strong	40
7	Structure of aTrypanosoma bruceiα/β-hydrolase fold protein with unknown function 2008 ·Acta Crystallographica Section F Structural Biology and Crystallization Communications ·E.A. Merritt,Margaret A. Holmes,Frederick S. Buckner,Wesley C. Van Voorhis,(unknown),Eric M. Phizicky,Angela Lauricella,Joseph R. Luft,George T. DeTitta,H. Neely,Frank Zucker,Wim G. J. Hol	3
8	Structure of ribose 5-phosphate isomerase fromPlasmodium falciparum 2006 ·Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Margaret A. Holmes,Frederick S. Buckner,Wesley C. Van Voorhis,Christophe L. M. J. Verlinde,Christopher Mehlin,Erica Boni,George T. DeTitta,Joseph R. Luft,Angela Lauricella,Lori Anderson,Oleksandr Kalyuzhniy,Frank Zucker,Lori W. Schoenfeld,Thomas Earnest,Wim G. J. Hol,E.A. Merritt	12
9	Structure of the conserved hypothetical protein MAL13P1.257 fromPlasmodium falciparum 2006 ·Acta Crystallographica Section F Structural Biology and Crystallization Communications ·Margaret A. Holmes,Frederick S. Buckner,Wesley C. Van Voorhis,Christopher Mehlin,Erica Boni,Thomas Earnest,George T. DeTitta,Joseph R. Luft,Angela Lauricella,Lori Anderson,Oleksandr Kalyuzhniy,Frank Zucker,Lori W. Schoenfeld,Wim G. J. Hol,E.A. Merritt	8
10	Siderocalin (Lcn 2) Also Binds Carboxymycobactins, Potentially Defending against Mycobacterial Infections through Iron Sequestration 2005 ·Structure ·Margaret A. Holmes,(unknown),Jide Xu,Colin Ratledge,Roland K. Strong	195
11	Lipocalin 2 mediates an innate immune response to bacterial infection by sequestrating ironbreakdown → 2004 ·Nature ·Trude Helen Flo,Kelly D. Smith,Shintaro Sato,David Rodríguez,Margaret A. Holmes,Roland K. Strong,Shizuo Akira,Alan Aderem	1438
12	HLA-E Allelic Variants 2003 ·Journal of Biological Chemistry ·Roland K. Strong,Margaret A. Holmes,Pingwei Li,Laura Braun,Ni Lee,Daniel E. Geraghty	252
13	The Neutrophil Lipocalin NGAL Is a Bacteriostatic Agent that Interferes with Siderophore-Mediated Iron Acquisitionbreakdown → 2002 ·Molecular Cell ·David H. Goetz,Margaret A. Holmes,Niels Borregaard,M.E. Bluhm,Kenneth N. Raymond,Roland K. Strong	1068
14	Structural Studies of Allelic Diversity of the MHC Class I Homolog MIC-B, a Stress-Inducible Ligand for the Activating Immunoreceptor NKG2D 2002 ·The Journal of Immunology ·Margaret A. Holmes,Pingwei Li,Effie W. Petersdorf,Roland K. Strong	53
15	“Superhumanized” Antibodies: Reduction of Immunogenic Potential by Complementarity-Determining Region Grafting with Human Germline Sequences: Application to an Anti-CD28 2002 ·The Journal of Immunology ·Philip Tan,David A. Mitchell,(unknown),Margaret A. Holmes,Claudio Anasetti,Jefferson Foote	70
16	Structural Effects of Framework Mutations on a Humanized Anti-Lysozyme Antibody 2001 ·The Journal of Immunology ·Margaret A. Holmes,(unknown),Jefferson Foote	18
17	Conformational Correction Mechanisms Aiding Antigen Recognition by a Humanized Antibody 1998 ·The Journal of Experimental Medicine ·Margaret A. Holmes,(unknown),Jefferson Foote	32
18	Structures of met and azidomet hemerythrin at 1·66 Å resolution 1991 ·Journal of Molecular Biology ·Margaret A. Holmes,Ronald E. Stenkamp	78
19	Structures of deoxy and oxy hemerythrin at 2.0 Å resolution 1991 ·Journal of Molecular Biology ·Margaret A. Holmes,I. Le Trong,S. Turley,Larry C. Sieker,Ronald E. Stenkamp	167
20	Crystallographic data for sturgeon holo-d-glyceraldehyde-3-phosphate dehydrogenase: A holo-d-glyceraldehyde-3-phosphate dehydrogenase with crystallographic 2-fold symmetry 1977 ·Journal of Molecular Biology ·Margaret A. Holmes,S. James Remington,(unknown),Gary Christie,Brian W. Matthews	5

About Margaret A. Holmes

Margaret A. Holmes is a scholar working on Virology, Hematology and Radiology, Nuclear Medicine and Imaging, having authored 21 papers that have together received 3.8k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (6 papers), Enzyme Structure and Function (5 papers) and Glycosylation and Glycoproteins Research (4 papers). The work is most often cited by research in Nephrology (606 citations), Immunology (1.0k citations) and Hematology (499 citations). Margaret A. Holmes has collaborated with scholars based in United States, South Africa and Portugal. Frequent co-authors include Roland K. Strong, Trude Helen Flo, David Rodríguez, Kelly D. Smith, Alan Aderem, Shintaro Sato, Shizuo Akira, Kenneth N. Raymond, David H. Goetz and M.E. Bluhm. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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