Manfred Köpf

36.2k total citations · 8 hit papers
234 papers, 25.3k citations indexed

About

Manfred Köpf is a scholar working on Immunology, Molecular Biology and Epidemiology. According to data from OpenAlex, Manfred Köpf has authored 234 papers receiving a total of 25.3k indexed citations (citations by other indexed papers that have themselves been cited), including 162 papers in Immunology, 47 papers in Molecular Biology and 33 papers in Epidemiology. Recurrent topics in Manfred Köpf's work include Immune Cell Function and Interaction (78 papers), T-cell and B-cell Immunology (67 papers) and Immunotherapy and Immune Responses (39 papers). Manfred Köpf is often cited by papers focused on Immune Cell Function and Interaction (78 papers), T-cell and B-cell Immunology (67 papers) and Immunotherapy and Immune Responses (39 papers). Manfred Köpf collaborates with scholars based in Switzerland, Germany and United States. Manfred Köpf's co-authors include Martin F. Bachmann, Georges Köhler, Benjamin J. Marsland, Michael Kurrer, Christoph Schneider, Samuel Philip Nobs, Marinus C. Lamers, Horst Bluethmann, Jonathan Muri and Nicole Schmitz and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Manfred Köpf

232 papers receiving 24.8k citations

Hit Papers

Impaired immune and acute-phase responses in interleukin-... 1993 2026 2004 2015 1994 1993 2015 2014 2014 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Impaired immune and acute-phase responses in interleukin-6-deficient mice
    1994 1.5k citations Manfred Köpf, Georges Köhler et al. profile →
  2. Disruption of the murine IL-4 gene blocks Th2 cytokine responses
    1993 1.0k citations Manfred Köpf, Martin F. Bachmann et al. profile →
  3. T cell lipid peroxidation induces ferroptosis and prevents immunity to infection
    2015 517 citations Mai Matsushita, Stefan Freigang et al. The Journal of Experimental Medicine profile →
  4. Induction of the nuclear receptor PPAR-γ by the cytokine GM-CSF is critical for the differentiation of fetal monocytes into alveolar macrophages
    2014 419 citations Christoph Schneider, Samuel Philip Nobs et al. profile →
  5. The development and function of lung-resident macrophages and dendritic cells
    2014 413 citations Manfred Köpf, Christoph Schneider et al. profile →
  6. Redox regulation of immunometabolism
    2020 351 citations Jonathan Muri, Manfred Köpf profile →
  7. Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
    2018 135 citations Manfred Köpf et al. profile →
  8. In vivo prime editing of a metabolic liver disease in mice
    2022 130 citations Desirée Böck, Tanja Rothgangl et al. Science Translational Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Manfred Köpf Switzerland 91 14.6k 5.6k 3.7k 3.4k 2.7k 234 25.3k
Matthias Mack Germany 84 13.3k 0.9× 5.9k 1.1× 2.9k 0.8× 4.7k 1.4× 1.8k 0.7× 259 25.3k
Bernhard Ryffel France 88 14.1k 1.0× 7.5k 1.4× 4.3k 1.1× 3.0k 0.9× 2.5k 0.9× 438 27.8k
Peter J. Murray United States 78 16.5k 1.1× 8.2k 1.5× 4.4k 1.2× 4.9k 1.5× 1.6k 0.6× 166 28.3k
Stefanie N. Vogel United States 86 15.6k 1.1× 7.0k 1.3× 4.5k 1.2× 2.5k 0.8× 1.4k 0.5× 328 24.6k
Stefan Endres Germany 83 16.6k 1.1× 9.0k 1.6× 3.5k 0.9× 5.0k 1.5× 1.8k 0.7× 276 28.6k
Craig Gérard United States 86 16.2k 1.1× 6.3k 1.1× 3.5k 0.9× 5.8k 1.7× 4.5k 1.6× 223 29.5k
Marco A. Cassatella Italy 75 13.6k 0.9× 5.2k 0.9× 2.1k 0.6× 3.6k 1.1× 2.3k 0.9× 240 21.7k
Sharon M. Wahl United States 87 15.0k 1.0× 7.9k 1.4× 3.1k 0.8× 4.4k 1.3× 2.7k 1.0× 277 31.6k
Raif S. Geha United States 99 19.4k 1.3× 5.3k 0.9× 2.4k 0.7× 2.7k 0.8× 4.6k 1.7× 501 31.8k
Martin F. Bachmann Switzerland 96 18.0k 1.2× 8.3k 1.5× 5.1k 1.4× 3.6k 1.1× 2.1k 0.8× 371 31.3k

Countries citing papers authored by Manfred Köpf

Since Specialization
Citations

This map shows the geographic impact of Manfred Köpf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manfred Köpf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manfred Köpf more than expected).

Fields of papers citing papers by Manfred Köpf

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manfred Köpf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manfred Köpf. The network helps show where Manfred Köpf may publish in the future.

Co-authorship network of co-authors of Manfred Köpf

This figure shows the co-authorship network connecting the top 25 collaborators of Manfred Köpf. A scholar is included among the top collaborators of Manfred Köpf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Manfred Köpf. Manfred Köpf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Schmid, Michael F., Ivan Berest, Jing Zhang, et al.. (2025). IL-1 protects from fatal systemic candidiasis in mice by inhibiting oxidative phosphorylation and hypoxia. Nature Communications. 16(1). 2626–2626. 1 indexed citations
2.
Cangkrama, Michael, Xiaoyu Wu, Christoph G. Gäbelein, et al.. (2025). MIRO2-mediated mitochondrial transfer from cancer cells induces cancer-associated fibroblast differentiation. Nature Cancer. 6(10). 1714–1733. 2 indexed citations
3.
Höpner, Sabine, Luigi Tortola, Irene Keller, et al.. (2024). IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy. Cell Reports Medicine. 5(11). 101826–101826. 6 indexed citations
4.
Marquart, Kim Fabiano, Nicolas Mathis, Lucas Kissling, et al.. (2024). Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs. Nature Methods. 21(11). 2084–2093. 8 indexed citations
5.
Böck, Desirée, Tanja Rothgangl, Lukas Villiger, et al.. (2022). In vivo prime editing of a metabolic liver disease in mice. Science Translational Medicine. 14(636). eabl9238–eabl9238. 130 indexed citations breakdown →
6.
Cangkrama, Michael, Mai Matsushita, Michela Di Filippo, et al.. (2022). A Protumorigenic mDia2–MIRO1 Axis Controls Mitochondrial Positioning and Function in Cancer-Associated Fibroblasts. Cancer Research. 82(20). 3701–3717. 14 indexed citations
7.
Matsushita, Mai, Jonathan Muri, Peter A. Bretscher, et al.. (2021). Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis. European Journal of Immunology. 51(10). 2417–2429. 39 indexed citations
8.
Nobs, Samuel Philip, et al.. (2021). GM-CSF instigates a dendritic cell–T-cell inflammatory circuit that drives chronic asthma development. Journal of Allergy and Clinical Immunology. 147(6). 2118–2133.e3. 28 indexed citations
9.
Nobs, Samuel Philip, Christoph Schneider, Alex K. Heer, et al.. (2016). PI3Kγ Is Critical for Dendritic Cell-Mediated CD8+ T Cell Priming and Viral Clearance during Influenza Virus Infection. PLoS Pathogens. 12(3). e1005508–e1005508. 20 indexed citations
10.
Banerjee, Indranil, Y. Miyake, Samuel Philip Nobs, et al.. (2014). Influenza A virus uses the aggresome processing machinery for host cell entry. Science. 346(6208). 473–477. 208 indexed citations
11.
Boettcher, Steffen, Rahel Gerosa, Ramin Radpour, et al.. (2014). Endothelial cells translate pathogen signals into G-CSF–driven emergency granulopoiesis. Blood. 124(9). 1393–1403. 211 indexed citations
12.
Attridge, Kesley, Chun Jing Wang, Lukasz Wardzinski, et al.. (2012). IL-21 inhibits T cell IL-2 production and impairs Treg homeostasis. Blood. 119(20). 4656–4664. 113 indexed citations
13.
Fröhlich, Anja, Jan Kisielow, Stefan Freigang, et al.. (2009). IL-21R on T Cells Is Critical for Sustained Functionality and Control of Chronic Viral Infection. Science. 324(5934). 1576–1580. 366 indexed citations
14.
Sonderegger, Ivo, Giandomenica Iezzi, Reinhard Maier, et al.. (2008). GM-CSF mediates autoimmunity by enhancing IL-6–dependent Th17 cell development and survival. The Journal of Experimental Medicine. 205(10). 2281–2294. 206 indexed citations
15.
Fröhlich, Anja, Benjamin J. Marsland, Ivo Sonderegger, et al.. (2006). IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood. 109(5). 2023–2031. 135 indexed citations
16.
Gatto, Dominique, Thomas D. Pfister, Andrea Jegerlehner, et al.. (2005). Complement receptors regulate differentiation of bone marrow plasma cell precursors expressing transcription factors Blimp-1 and XBP-1. The Journal of Experimental Medicine. 201(6). 993–1005. 62 indexed citations
17.
Camoglio, Luisa, et al.. (2002). Contrasting roles of IL-12p40 and IL-12p35 in the development of hapten-induced colitis. Pure Amsterdam UMC. 1 indexed citations
18.
Noffz, Gabriele, Zhihai Qin, Manfred Köpf, & Thomas Blankenstein. (1998). Neutrophils but Not Eosinophils Are Involved in Growth Suppression of IL-4-Secreting Tumors. The Journal of Immunology. 160(1). 345–350. 62 indexed citations
19.
Mohrs, Markus, et al.. (1998). Differences between IL-4Rα-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses. Current Biology. 8(11). 669–672. 180 indexed citations
20.
Köpf, Manfred, Frank Brombacher, Georges Köhler, et al.. (1996). IL-4-deficient Balb/c mice resist infection with Leishmania major.. The Journal of Experimental Medicine. 184(3). 1127–1136. 231 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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