Lynn Bedford

2.0k citations

21 papers · 1.6k indexed · h-index 18

Impact in

Cell Biology top 5%
- Endoplasmic Reticulum Stress and Disease
Molecular Biology top 10%
- Ubiquitin and proteasome pathways
- Protein Degradation and Inhibitors

Papers in

Cell Biology 6
- Endoplasmic Reticulum Stress and Disease 5
Neurology 5
- Parkinson's Disease Mechanisms and Treatments 4

Co-authors: R. John Mayer James Lowe Lawrence R. Dick James E. Brownell Simon Paine Paul W. Sheppard Robert Layfield Jeroen Roelofs
Journals: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease (2 papers)Essays in Biochemistry (2 papers)PLoS ONE (2 papers)Autophagy (1 paper)Scientific Reports (1 paper)
Partner nations: United Kingdom United States Libya

In The Last Decade

Lynn Bedford

21 papers receiving 1.6k citations

Peers

Countries citing papers authored by Lynn Bedford

Since Specialization

Citations

This map shows the geographic impact of Lynn Bedford's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lynn Bedford with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lynn Bedford more than expected).

Fields of papers citing papers by Lynn Bedford

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lynn Bedford. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lynn Bedford. The network helps show where Lynn Bedford may publish in the future.

Co-authors

The 25 scholars most cited alongside Lynn Bedford, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lynn Bedford Line = papers co-authored together Lynn Bedford links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	The Calcineurin-TFEB-p62 Pathway Mediates the Activation of Cardiac Macroautophagy by Proteasomal Malfunction Circulation Research ·Bo Pan, Jie Li, Nirmal Parajuli, Zongwen Tian, Penglong Wu, Megan T. Lewno, Jianqiu Zou, Wenjuan Wang, Lynn Bedford, R. John Mayer, Jing Fang, Jinbao Liu, Taixing Cui, Huabo Su, Xuejun Wang	2020	82
2	Monoamine oxidase-A promotes protective autophagy in human SH-SY5Y neuroblastoma cells through Bcl-2 phosphorylation Redox Biology ·Aslihan Ugun‐Klusek, Theodosis S. Theodosi, Julia C. Fitzgerald, Florence Burté, Christoph Ufer, David J. Boocock, Patrick Yu‐Wai‐Man, Lynn Bedford, E. Ellen Billett	2018	35
3	Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons Scientific Reports ·Philippine C. Geiszler, Aslihan Ugun‐Klusek, Karen Lawler, Marie‐Christine Pardon, Yuchun Ding, Li Bai, Clare A. Daykin, Dorothee P. Auer, Lynn Bedford	2018	10
4	Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway Cell Death and Disease ·Aslihan Ugun‐Klusek, Michael H. Tatham, Jamal Elkharaz, Dumitru Constantin‐Teodosiu, Karen Lawler, Hala Alhadi Ali Mohamed, Simon Paine, G. D. Anderson, R. John Mayer, James Lowe, E. Ellen Billett, Lynn Bedford	2017	45
5	Alcohol-Related Brain Damage in Humans PLoS ONE ·Amaia M. Erdozain, Benito Morentín, Lynn Bedford, Emma King, David Tooth, Charlotte Brewer, Declan Wayne, Laura Johnson, Henry K. Gerdes, Peter Wigmore, Luís F. Callado, Wayne G. Carter	2014	32
6	Proteasome Dysfunction Activates Autophagy and the Keap1-Nrf2 Pathway Journal of Biological Chemistry ·Shun Kageyama, Yu‐shin Sou, Takefumi Uemura, Satoshi Kametaka, Tetsuya Saito, Ryosuke Ishimura, Tsuguka Kouno, Lynn Bedford, R. John Mayer, Myung‐Shik Lee, Masayuki Yamamoto, Satoshi Waguri, Keiji Tanaka, Masaaki Komatsu	2014	95
7	Pale Body-Like Inclusion Formation and Neurodegeneration following Depletion of 26S Proteasomes in Mouse Brain Neurones are Independent of α-Synuclein PLoS ONE ·Simon Paine, Glenn Anderson, Karen Bedford, Karen Lawler, R. John Mayer, James Lowe, Lynn Bedford	2013	25
8	Implications for oxidative stress and astrocytes following 26S proteasomal depletion in mouse forebrain neurones Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Jamal Elkharaz, Aslihan Ugun‐Klusek, Dumitru Constantin‐Teodosiu, Karen Lawler, R. John Mayer, E. Ellen Billett, James Lowe, Lynn Bedford	2013	21
9	Heterozygosity for the proteasomal Psmc1 ATPase is insufficient to cause neuropathology in mouse brain, but causes cell cycle defects in mouse embryonic fibroblasts Neuroscience Letters ·Nooshin Rezvani, Jamal Elkharaz, Karen Lawler, Maureen Mee, R. John Mayer, Lynn Bedford	2012	8
10	Diverse polyubiquitin chains accumulate following 26S proteasomal dysfunction in mammalian neurones Neuroscience Letters ·Lynn Bedford, Robert Layfield, R. John Mayer, Junmin Peng, Ping Xu	2011	20
11	CRMP2 Hyperphosphorylation is Characteristic of Alzheimer's Disease and not a Feature Common to Other Neurodegenerative Diseases Journal of Alzheimer s Disease ·Ritchie Williamson, Lidy van Aalten, David M. A. Mann, Bettina Platt, Florian Plattner, Lynn Bedford, John Mayer, David Howlett, Alessia Usardi, Calum Sutherland, Adam R. Cole	2011	53
12	Assembly, structure, and function of the 26S proteasome Trends in Cell Biology ·Lynn Bedford, Simon Paine, Paul W. Sheppard, R. John Mayer, Jeroen Roelofs	2010	208
13	Ubiquitin-like protein conjugation and the ubiquitin–proteasome system as drug targets Nature Reviews Drug Discovery ·Lynn Bedford, James Lowe, Lawrence R. Dick, R. John Mayer, James E. Brownell	2010	441
14	Immunoreactivity to Lys63-linked polyubiquitin is a feature of neurodegeneration Neuroscience Letters ·Simon Paine, Lynn Bedford, Julian R. Thorpe, R. John Mayer, James R. Cavey, Nin Bajaj, Paul W. Sheppard, James Lowe, Robert Layfield	2009	34
15	The UPS and autophagy in chronic neurodegenerative disease: Six of one and half a dozen of the other—Or not? Autophagy ·Lynn Bedford, Simon Paine, Nooshin Rezvani, Maureen Mee, James Lowe, R. John Mayer	2009	21
16	Is malfunction of the ubiquitin proteasome system the primary cause of α-synucleinopathies and other chronic human neurodegenerative disease? Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Lynn Bedford, David Hay, Simon Paine, Nooshin Rezvani, Maureen Mee, James Lowe, R. John Mayer	2008	26
17	Depletion of 26S Proteasomes in Mouse Brain Neurons Causes Neurodegeneration and Lewy-Like Inclusions Resembling Human Pale Bodies Journal of Neuroscience ·Lynn Bedford, David Hay, Anny Devoy, Simon Paine, Des G. Powe, Rashmi Seth, Trevor Gray, Ian Topham, K.C.F. Fone, Nooshin Rezvani, Maureen Mee, Tim Soane, Robert Layfield, Paul W. Sheppard, Ted Ebendal, Dmitry Usoskin, James Lowe, R. John Mayer	2008	250
18	The ubiquitin–proteasome system and neurodegenerative disorders Essays in Biochemistry ·Robert Layfield, James Lowe, Lynn Bedford	2005	57
19	Id4 is required for the correct timing of neural differentiation Developmental Biology ·Lynn Bedford, Robert L. Walker, Tôru Kondo, Ingeborg van Crüchten, Emerson R. King, Fred Sablitzky	2005	64
20	The ubiquitin–proteasome system and neurodegenerative disorders Essays in Biochemistry ·Robert Layfield, James Lowe, Lynn Bedford	2005	38

About Lynn Bedford

Lynn Bedford is a scholar working on Cell Biology, Neurology, Epidemiology, Molecular Biology and Neurology, having authored 21 papers that have together received 1.6k indexed citations. Recurring topics across this work include Ubiquitin and proteasome pathways (14 papers), Autophagy in Disease and Therapy (10 papers), Endoplasmic Reticulum Stress and Disease (5 papers), Genetics and Neurodevelopmental Disorders (5 papers), Parkinson's Disease Mechanisms and Treatments (4 papers), Mitochondrial Function and Pathology (4 papers), Lysosomal Storage Disorders Research (2 papers) and Genetic Neurodegenerative Diseases (2 papers). The work is most often cited by research in Cell Biology (361 citations), Molecular Biology (1.1k citations), Neurology (112 citations), Neurology (197 citations) and Aging (20 citations). Lynn Bedford has collaborated with scholars based in United Kingdom, United States and Libya. Frequent co-authors include R. John Mayer, James Lowe, Lawrence R. Dick, James E. Brownell, Simon Paine, Paul W. Sheppard, Robert Layfield, Jeroen Roelofs, Maureen Mee and David Hay. Their work appears in journals such as Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, Essays in Biochemistry, PLoS ONE, Autophagy and Scientific Reports.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact