Luı́s de Lecea

32.6k total citations · 10 hit papers
203 papers, 24.4k citations indexed

About

Luı́s de Lecea is a scholar working on Cognitive Neuroscience, Endocrine and Autonomic Systems and Cellular and Molecular Neuroscience. According to data from OpenAlex, Luı́s de Lecea has authored 203 papers receiving a total of 24.4k indexed citations (citations by other indexed papers that have themselves been cited), including 130 papers in Cognitive Neuroscience, 110 papers in Endocrine and Autonomic Systems and 68 papers in Cellular and Molecular Neuroscience. Recurrent topics in Luı́s de Lecea's work include Sleep and Wakefulness Research (115 papers), Circadian rhythm and melatonin (87 papers) and Sleep and related disorders (48 papers). Luı́s de Lecea is often cited by papers focused on Sleep and Wakefulness Research (115 papers), Circadian rhythm and melatonin (87 papers) and Sleep and related disorders (48 papers). Luı́s de Lecea collaborates with scholars based in United States, Spain and Switzerland. Luı́s de Lecea's co-authors include Antoine Adamantidis, J. Gregor Sutcliffe, Thomas S. Kilduff, Karl Deisseroth, Anthony N. van den Pol, Christelle Peyron, J G Sutcliffe, H. Craig Heller, Patria E. Danielson and Matthew E. Carter and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Luı́s de Lecea

203 papers receiving 24.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The hypocretins: Hypothalamus-specific peptides with neuroexcitatory activity

1998 3.0k citations Luı́s de Lecea, Thomas S. Kilduff et al. profile →
Neurons Containing Hypocretin (Orexin) Project to Multiple Neuronal Systems

1998 2.8k citations Luı́s de Lecea, Thomas S. Kilduff et al. Journal of Neuroscience profile →
Neural substrates of awakening probed with optogenetic control of hypocretin neurons

2007 933 citations Antoine Adamantidis, Karl Deisseroth et al. profile →
Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

2009 914 citations Hsing-Chen Tsai, Feng Zhang et al. Science profile →
Tuning arousal with optogenetic modulation of locus coeruleus neurons

2010 673 citations Matthew E. Carter, Antoine Adamantidis et al. Nature Neuroscience profile →
A novel adenylyl cyclase-activating serotonin receptor (5-HT7) implicated in the regulation of mammalian circadian rhythms

1993 590 citations Luı́s de Lecea et al. profile →
Hypocretin/Orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems

1998 576 citations Luı́s de Lecea et al. profile →
Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

2010 514 citations Antoine Adamantidis, Luı́s de Lecea et al. profile →
VTA dopaminergic neurons regulate ethologically relevant sleep–wake behaviors

2016 398 citations Luı́s de Lecea et al. Nature Neuroscience profile →
Non-invasive transcranial ultrasound stimulation for neuromodulation

2021 175 citations Luı́s de Lecea et al. profile →

Peers

Countries citing papers authored by Luı́s de Lecea

Since Specialization

Citations

This map shows the geographic impact of Luı́s de Lecea's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luı́s de Lecea with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luı́s de Lecea more than expected).

Fields of papers citing papers by Luı́s de Lecea

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luı́s de Lecea. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luı́s de Lecea. The network helps show where Luı́s de Lecea may publish in the future.

Co-authorship network of co-authors of Luı́s de Lecea

This figure shows the co-authorship network connecting the top 25 collaborators of Luı́s de Lecea. A scholar is included among the top collaborators of Luı́s de Lecea based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luı́s de Lecea. Luı́s de Lecea is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Aging and injury drive neuronal senescence in the dorsal root ganglia 2025 ·Nature Neuroscience ·(unknown), (unknown), Sabrina F. Bond, (unknown), (unknown), Laura Colman, Claire E. Jordan, (unknown), (unknown), (unknown), Luı́s de Lecea, Marco Quarta, Julie A. Kauer, Vivianne L. Tawfik	7
2	In vivo photocontrol of orexin receptors with a nanomolar light-regulated analogue of orexin-B 2024 ·Cellular and Molecular Life Sciences ·(unknown), (unknown), Alexandre M. J. Gomila, Carlo Matera, Salvador Guardiola, Diane Nepomuceno, Mónica Varese, Pascal Bonaventure, Luı́s de Lecea, Ernest Giralt, Pau Gorostiza	3
3	The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection 2023 ·PLoS Biology ·Juan F. Quintana, Matthew C. Sinton, (unknown), Lalit Kumar Dubey, (unknown), (unknown), Michael Haley, Gail McConnell, Nono-Raymond Kuispond Swar, Dieudonné Mumba Ngoyi, David Bending, Luı́s de Lecea, Annette MacLeod, Neil A. Mabbott	8
4	Hyperexcitable arousal circuits drive sleep instability during aging 2022 ·Science ·Shi‐Bin Li, Valentina Martínez Damonte, Chong Chen, Gordon Wang, Justus M. Kebschull, Hiroshi Yamaguchi, W Bian, Carolin Purmann, Reenal Pattni, Alexander E. Urban, Philippe Mourrain, Julie A. Kauer, Grégory Scherrer, Luı́s de Lecea	103
5	Single cell and spatial transcriptomic analyses reveal microglia-plasma cell crosstalk in the brain during Trypanosoma brucei infection 2022 ·Nature Communications ·Juan F. Quintana, (unknown), Matthew C. Sinton, Emma M. Briggs, Thomas D. Otto, (unknown), (unknown), Colin Loney, Luı́s de Lecea, Neil A. Mabbott, Annette MacLeod	29
6	Orexin receptors in GtoPdb v.2021.3 2021 ·IUPHAR/BPS Guide to Pharmacology CITE ·Paul J. Coleman, Luı́s de Lecea, Anthony L. Gotter, Jim J. Hagan, Daniël Hoyer, Thomas S. Kilduff, Jyrki P. Kukkonen, Rod A. Porter, John J. Renger, Jerome M. Siegel, (unknown), Neil Upton, Christopher J. Winrow	3
7	Neurobiological and Hormonal Mechanisms Regulating Women’s Sleep 2021 ·Frontiers in Neuroscience ·(unknown), Luı́s de Lecea, Kimberly J. Jennings	52
8	Hypocretin/orexin deficiency decreases cocaine abuse liability 2018 ·Neuropharmacology ·(unknown), (unknown), Takeshi Sakurai, Masashi Yanagisawa, Luı́s de Lecea, Pierre J. Magistretti, Olivier Halfon, Benjamin Boutrel	30
9	Rat intersubjective decisions are encoded by frequency‐specific oscillatory contexts 2017 ·Brain and Behavior ·Jana Schaich Borg, Sanvesh Srivastava, Lizhen Lin, Joseph Heffner, David B. Dunson, Kafui Dzirasa, Luı́s de Lecea	12
10	Potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease 2014 ·The Journal of Experimental Medicine ·Jee Hoon Roh, Hong Jiang, Mary Beth Finn, Floy R. Stewart, Thomas E. Mahan, John R. Cirrito, (unknown), B. Joy Snider, Mingjie Li, Masashi Yanagisawa, Luı́s de Lecea, David M. Holtzman	184
11	Hypocretin (orexin) regulation of sleep-to-wake transitions 2014 ·Frontiers in Pharmacology ·Luı́s de Lecea, Ramón Huerta	93
12	Functional wiring of hypocretin and LC-NE neurons: implications for arousal 2013 ·Frontiers in Behavioral Neuroscience ·Matthew E. Carter, Luı́s de Lecea, Antoine Adamantidis	54
13	Hypocretins and the neurobiology of sleep–wake mechanisms 2012 ·Progress in brain research ·Luı́s de Lecea	66
14	Plasma levels of neuropeptides and metabolic hormones, and sleepiness in obstructive sleep apnea 2011 ·Respiratory Medicine ·Manuel Sánchez‐de‐la‐Torre, Antònia Barceló, Javier Piérola, Cristina Esquinas, Mónica de la Peña, Joaquín Durán‐Cantolla, F. Capote, Juan F. Masa, José M. Marı́n, (unknown), Gonzalo Cao, Montserrat Martínez‐Alonso, Luı́s de Lecea, David Gozal, Josep M. Montserrat, Ferrán Barbé	26
15	Reelin Regulates Postnatal Neurogenesis and Enhances Spine Hypertrophy and Long-Term Potentiation 2010 ·Journal of Neuroscience ·Lluı́s Pujadas, Agnès Gruart, Carles Bosch, Lídia Delgado, Cátia M. Teixeira, Daniela Rossi, Luı́s de Lecea, Albert Martı́nez, José M. Delgado‐García, Eduardo Soriano	171
16	Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning breakdown → 2009 ·Science ·Hsing-Chen Tsai, Feng Zhang, Antoine Adamantidis, Garret D. Stuber, Antonello Bonci, Luı́s de Lecea, Karl Deisseroth	914
17	The Hypocretins and their Role in Narcolepsy 2009 ·CNS & Neurological Disorders - Drug Targets ·(unknown), Luı́s de Lecea	18
18	Effect of cortistatin on tau phosphorylation at Ser262 site 2008 ·Journal of Neuroscience Research ·Alicia Rubio, Mar Pérez, Luı́s de Lecea, Jesús Ávila	11
19	Transgenic Mice with a Reduced Core Body Temperature Have an Increased Life Span 2006 ·Science ·Bruno Conti, Manuel Sánchez-Alavez, Raphaëlle Winsky‐Sommerer, Maria C. Morale, Jacinta Lucero, Sara E. Brownell, Véronique Fabre, Salvador Huitrón‐Reséndiz, Steven J. Henriksen, Eric P. Zorrilla, Luı́s de Lecea, Tamás Bartfai	304
20	Late appearance of parvalbumin-immunoreactive neurons in the rodent cerebral cortex does not follow an ‘inside-out’ sequence 1992 ·Neuroscience Letters ·Eduardo Soriano, José Antonio del Rı́o, Isidró Ferrer, (unknown), Luı́s de Lecea, Soledad Alcántara	38

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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