Luc Koymans

5.6k citations

30 papers · 4.5k indexed · 1 hit paper · h-index 19

Co-authors: Daniel W. Nebert David J. Waxman David R. Nelson Michael R. Waterman Osamu Gotoh René Feyereisen I. C. Gunsalus Minor J. Coon
Topics: Pharmacogenetics and Drug Metabolism (12 papers)Computational Drug Discovery Methods (7 papers)HIV/AIDS drug development and treatment (7 papers)
Cited by: Pharmacology Virology Infectious Diseases
Journals: Journal of Molecular Biology Free Radical Biology and Medicine Annals of the New York Academy of Sciences
Partner nations: Belgium Netherlands United States

In The Last Decade

Luc Koymans

30 papers receiving 4.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclature

1996 2.4k citations David R. Nelson, Luc Koymans et al. Pharmacogenetics profile →

Peers

Countries citing papers authored by Luc Koymans

Since Specialization

Citations

This map shows the geographic impact of Luc Koymans's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luc Koymans with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luc Koymans more than expected).

Fields of papers citing papers by Luc Koymans

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luc Koymans. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luc Koymans. The network helps show where Luc Koymans may publish in the future.

Co-authorship network of co-authors of Luc Koymans

This figure shows the co-authorship network connecting the top 25 collaborators of Luc Koymans. A scholar is included among the top collaborators of Luc Koymans based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luc Koymans. Luc Koymans is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Inhibition and substrate recognition – a computational approach applied to HIV protease 2003 ·Journal of Computer-Aided Molecular Design ·H. Maarten Vinkers,Marc R. de Jonge,(unknown),Jan Heeres,Luc Koymans,(unknown),Paul Lewi,H. Timmerman,Paul A. J. Janssen	10
2	Cytochrome P450 Database 2001 ·SAR and QSAR in environmental research ·Andrey Lisitsa,(unknown),I. I. Karuzina,A. I. Archakov,Luc Koymans	18
3	Review Article Cytochromes P450 in fungi 1998 ·Mycoses ·H. Vanden Bossche,Luc Koymans	67
4	Amino Acid Substitutions in the Cytochrome P-450 Lanosterol 14α-Demethylase (CYP51A1) from Azole-Resistant Candida albicans Clinical Isolates Contribute to Resistance to Azole Antifungal Agents 1998 ·Antimicrobial Agents and Chemotherapy ·Dominique Sanglard,Françoise Ischer,Luc Koymans,Jacques Billé	391
5	The α and ω of G Protein–Coupled Receptors 1997 ·Annals of the New York Academy of Sciences ·Henri Moereels,Paul Lewi,Luc Koymans,Paul A. J. Janssen	2
6	Crystal Structures of 8-Cl and 9-Cl TIBO Complexed with Wild-type HIV-1 RT and 8-Cl TIBO Complexed with the Tyr181Cys HIV-1 RT Drug-resistant Mutant 1996 ·Journal of Molecular Biology ·Kalyan Das,Jianping Ding,Y. Hsiou,Arthur D. Clark,Henri Moereels,Luc Koymans,Koen Andries,Rudi Pauwels,Paul A. J. Janssen,Paul L. Boyer,Patrick K. Clark,Richard H. Smith,Marilyn B. Kroeger Smith,Christopher J. Michejda,Stephen H. Hughes,Eddy Arnold	159
7	P450 superfamily: update on new sequences, gene mapping, accession numbers and nomenclaturebreakdown → 1996 ·Pharmacogenetics ·David R. Nelson,Luc Koymans,Tetsuya Kamataki,John J. Stegeman,René Feyereisen,David J. Waxman,Michael R. Waterman,Osamu Gotoh,Minor J. Coon,(unknown),I. C. Gunsalus,Daniel W. Nebert	2397
8	Molecular modeling studies of HIV‐1 reverse transcriptase nonnucleoside inhibitors: Total energy of complexation as a predictor of drug placement and activity 1995 ·Protein Science ·Marilyn B. Kroeger Smith,Stephen H. Hughes,Paul L. Boyer,Christopher J. Michejda,Carol A. Rouzer,Lisa A. Taneyhill,Richard H. Smith,Nathan Smith,(unknown),(unknown),Luc Koymans,Eddy Arnold,(unknown),Kalyan Das,Wanyi Zhang	55
9	A molecular model for the interaction between vorozole and other non-steroidal inhibitors and human cytochrome P450 19 (P450 Aromatase) 1995 ·The Journal of Steroid Biochemistry and Molecular Biology ·Luc Koymans,Henri Moereels,H. Vanden Bossche	41
10	Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors 1995 ·Nature Structural & Molecular Biology ·Jianping Ding,Kalyan Das,(unknown),Luc Koymans,(unknown),(unknown),(unknown),Eddy Arnold	254
11	P450 inhibitors of use in medical treatment: Focus on mechanisms of action 1995 ·Pharmacology & Therapeutics ·H. Vanden Bossche,Luc Koymans,(unknown)	118
12	Aromatase inhibitors ? mechanisms for non-steroidal inhibitors 1994 ·Breast Cancer Research and Treatment ·H. Vanden Bossche,Henri Moereels,Luc Koymans	60
13	Molecular pharmacology of vitamin E: Structural aspects of antioxidant activity 1993 ·Free Radical Biology and Medicine ·S.A.B.E. van Acker,Luc Koymans,Aalt Bast	214
14	Generalized cytochrome P450-mediated oxidation and oxygenation reactions in aromatic substrates with activated N-H, O-H, C-H, or S-H substituents 1993 ·Xenobiotica ·Luc Koymans,Gabriëlle M. Donné-Op den Kelder,J.M. te Koppele,Nico Vermeulen	17
15	Computational chemistry in biotransformational and toxicological research 1993 ·Pharmacy World & Science ·Luc Koymans	2
16	A preliminary 3D model for cytochrome P450 2D6 constructed by homology model building 1993 ·Journal of Computer-Aided Molecular Design ·Luc Koymans,Nico Vermeulen,(unknown),(unknown)	52
17	Cytochromes P450: Their Active-Site Structure and Mechanism of Oxidation 1993 ·Drug Metabolism Reviews ·Luc Koymans,Gabriëlle M. Donné-Op den Kelder,J.M. te Koppele,Nico Vermeulen	42
18	A predictive model for substrates of cytochrome P450-debrisoquine (2D6) 1992 ·Chemical Research in Toxicology ·Luc Koymans,Nico Vermeulen,S.A.B.E. van Acker,J.M. te Koppele,J. Heykants,Karel Lavrijsen,W. Meuldermans,Gabriëlle M. Donné-Op den Kelder	125
19	Mechanisms of activation of phenacetin to reactive metabolites by cytochrome P-450: a theoretical study involving radical intermediates. 1990 ·Molecular Pharmacology ·Luc Koymans,Joop H. van Lenthe,Gabriëlle M. Donné-Op den Kelder,Nico Vermeulen	18
20	A theoretical study on the metabolic activation of paracetamol by cytochrome P-450: indications for a uniform oxidation mechanism 1989 ·Chemical Research in Toxicology ·Luc Koymans,Joop H. van Lenthe,R. van de Straat,Gabriëlle M. Donné-Op den Kelder,Nico Vermeulen	35

About Luc Koymans

Luc Koymans is a scholar working on Pharmacology, Virology and Infectious Diseases, having authored 30 papers that have together received 4.5k indexed citations. Recurring topics across this work include Pharmacogenetics and Drug Metabolism (12 papers), Computational Drug Discovery Methods (7 papers) and HIV/AIDS drug development and treatment (7 papers). The work is most often cited by research in Pharmacology (1.9k citations), Virology (387 citations) and Infectious Diseases (1.1k citations). Luc Koymans has collaborated with scholars based in Belgium, Netherlands and United States. Frequent co-authors include Daniel W. Nebert, David J. Waxman, David R. Nelson, Michael R. Waterman, Osamu Gotoh, René Feyereisen, I. C. Gunsalus, Minor J. Coon, John J. Stegeman and Tetsuya Kamataki. Their work appears in journals such as Journal of Molecular Biology, Free Radical Biology and Medicine and Annals of the New York Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact