Lothar Steidler

6.0k citations

61 papers · 4.6k indexed · 2 hit papers · h-index 28

Impact in

Food Science top 0.2%
- Probiotics and Fermented Foods
Biotechnology top 0.5%
- Cancer Research and Treatments

Papers in

Food Science 25
- Probiotics and Fermented Foods 25
Biotechnology 11
- Cancer Research and Treatments 8

Co-authors: Erik Remaut Sabine Neirynck Pieter Rottiers Wolfgang Hans Walter Fiers Florian Obermeier Werner Falk Nathalie Huyghebaert
Journals: Applied and Environmental Microbiology (6 papers)Gastroenterology (4 papers)Biotechnology and Bioengineering (2 papers)Diabetes (2 papers)Annals of the New York Academy of Sciences (2 papers)
Partner nations: Belgium Ireland United States

In The Last Decade

Lothar Steidler

61 papers receiving 4.4k citations

Hit Papers

align trajectories log scale

A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease 2006 · 571 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2006 Clinical Gastroenterology and Hepatology
2000 Science

Peers

Countries citing papers authored by Lothar Steidler

Since Specialization

Citations

This map shows the geographic impact of Lothar Steidler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lothar Steidler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lothar Steidler more than expected).

Fields of papers citing papers by Lothar Steidler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lothar Steidler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lothar Steidler. The network helps show where Lothar Steidler may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lothar Steidler, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lothar Steidler Line = papers co-authored together Lothar Steidler links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A first-in-human, open-label Phase 1b and a randomised, double-blind Phase 2a clinical trial in recent-onset type 1 diabetes with AG019 as monotherapy and in combination with teplizumab Diabetologia ·Chantal Mathieu, Alice Wiedeman, Karen Cerosaletti, S. Alice Long, Locatelli Franco, Laura G. Cooney, Joan Vermeiren, Silvia Caluwaerts, Karolien Van Huynegem, Lothar Steidler, Tony Heffernan, Pieter Rottiers, Gerald T. Nepom, Kevan C. Herold, (unknown)	2023	38
2	Intestinal Delivery of Proinsulin and IL-10 via Lactococcus lactis Combined With Low-Dose Anti-CD3 Restores Tolerance Outside the Window of Acute Type 1 Diabetes Diagnosis Frontiers in Immunology ·Dana P. Cook, João Paulo Monteiro Carvalho Móri da Cunha, Pieter-Jan Martens, Sayera Aznabi, Francesca Mancarella, Giuliana Ventriglia, Guido Sebastiani, An-Sofie Vanherwegen, Mark A. Atkinson, Karolien Van Huynegem, Lothar Steidler, Silvia Caluwaerts, Pieter Rottiers, Luc Teyton, Francesco Dotta, Conny Gysemans, Chantal Mathieu	2020	23
3	Interleukin-27 Is a Potential Rescue Therapy for Acute Severe Colitis Through Interleukin-10–Dependent, T-Cell–Independent Attenuation of Colonic Mucosal Innate Immune Responses Inflammatory Bowel Diseases ·Mairi H McLean, Caroline Andrews, Miranda L. Hanson, Walter A. Baseler, Miriam R. Anver, Emilee Senkevitch, Ohne Spinnstubenromantik, Christopher Smith, Luke C. Davies, Julie A. Hixon, Junhao Cheng, Wei Shen, Lothar Steidler, Scott K. Durum	2017	27
4	PTU-103 Intra-luminal Interleukin (il)-27 Is A Potential Future Therapeutic For Inflammatory Bowel Disease Gut ·Олена Володимирівна Коротунова, Paramita Banerjee, И. Б. Федоров, 장석만, Amikam El'Ad, Xiaolin Wu, S. Kol-ov, Lothar Steidler, �ngeles Castro Iglesias	2014	1
5	Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice Journal of Clinical Investigation ·Tatiana Takiishi, Hannelie Korf, Tom L. Van Belle, Sofie Robert, Fabio Arturo Grieco, Silvia Caluwaerts, Letizia Galleri, Isabella Spagnuolo, Lothar Steidler, Karolien Van Huynegem, Pieter Demetter, Clive Wasserfall, Mark A. Atkinson, Francesco Dotta, Pieter Rottiers, Conny Gysemans, Chantal Mathieu	2012	148
6	AG013, a mouth rinse formulation of Lactococcus lactis secreting human Trefoil Factor 1, provides a safe and efficacious therapeutic tool for treating oral mucositis Oral Oncology ·Silvia Caluwaerts, Klaas Vandenbroucke, Lothar Steidler, Sabine Neirynck, Peter Vanhoenacker, Sam Corveleyn, Brynmor A. Watkins, Stephen T. Sonis, Bernard Coulie, Pieter Rottiers	2010	99
7	Actobiotics™ as a Novel Method for Cytokine Delivery Annals of the New York Academy of Sciences ·Lothar Steidler, Pieter Rottiers, Bernard Coulie	2009	33
8	Effect of a mouth rinse formulation with human trefoil factor 1-secreting Lactococcus lactis in experimental oral mucositis in hamsters Journal of Clinical Oncology ·Pieter Rottiers, Silvia Caluwaerts, Lothar Steidler, Klaas Vandenbroucke, Brynmor A. Watkins, S. Sonis, Bernard Coulie	2009	6
9	Oral administration of an IL-10–secreting Lactococcus lactis strain prevents food-induced IgE sensitization Journal of Allergy and Clinical Immunology ·C Frossard, Lothar Steidler, Philippe Eigenmann	2007	114
10	A Phase I Trial With Transgenic Bacteria Expressing Interleukin-10 in Crohn’s Disease Clinical Gastroenterology and Hepatology ·Henri Braat, Pieter Rottiers, Daniël W. Hommes, Nathalie Huyghebaert, Erik Remaut, Jean‐Paul Remon, Sander J. H. van Deventer, Sabine Neirynck, Maikel P. Peppelenbosch, Lothar Steidler Hit paper breakdown →	2006	571
11	Therapeutic Drug Delivery by Genetically Modified Lactococcus lactis Annals of the New York Academy of Sciences ·Lothar Steidler, Pieter Rottiers	2006	45
12	Delivery of Therapeutic Proteins throughLactococcus lactis Biotechnology and Genetic Engineering Reviews ·Sabine Neirynck, Lothar Steidler	2006	4
13	Live genetically modified bacteria as drug delivery tools: at the doorstep of a new pharmacology? Expert Opinion on Biological Therapy ·Lothar Steidler	2004	1
14	Active delivery of trefoil factors by genetically modified Lactococcus lactis prevents and heals acute colitis in mice Gastroenterology ·Klaas Vandenbroucke, Wolfgang Hans, Jacques Van Huysse, Sabine Neirynck, Pieter Demetter, Erik Remaut, Pieter Rottiers, Lothar Steidler	2004	216
15	Evaluation of extrusion/spheronisation, layering and compaction for the preparation of an oral, multi-particulate formulation of viable, hIL-10 producing Lactococcus lactis European Journal of Pharmaceutics and Biopharmaceutics ·Nathalie Huyghebaert, A. Vermeire, Sabine Neirynck, Lothar Steidler, E. Remaut, Jean Paul Remon	2004	15
16	Morphological study of interleukin-10 producing Lactococcus Lactis in mouse ileal loops Ghent University Academic Bibliography (Ghent University) ·Anouk Waeytens, Sabine Neirynck, Wim Waelput, Lothar Steidler, Claude Cuvelier	2003	1
17	In situ Delivery of Therapeutic Proteins by Recombinant Lactococcus lactis The Journal of Microbiology ·Lothar Steidler	2003	6
18	Genetically engineered probiotics Best Practice & Research Clinical Gastroenterology ·Lothar Steidler	2003	95
19	Biological containment of genetically modified Lactococcus lactis for intestinal delivery of human interleukin 10 Nature Biotechnology ·Lothar Steidler, Sabine Neirynck, Nathalie Huyghebaert, Veerle Snoeck, A. Vermeire, Bruno Goddeeris, Eric Cox, Jean Paul Remon, Erik Remaut	2003	405
20	Simultaneous light emission from cloned Vibrio fischeri lux genes and expression of LamB or LamB–protein A fusion proteins in Escherichia coli depends on using a single chimeric operon Biotechnology and Bioengineering ·Lothar Steidler, Akihiko Kato, Erik Remaut	1995	1

About Lothar Steidler

Lothar Steidler is a scholar working on Food Science, Biotechnology, Genetics, Endocrinology and Nutrition and Dietetics, having authored 61 papers that have together received 4.6k indexed citations. Recurring topics across this work include Probiotics and Fermented Foods (25 papers), Gut microbiota and health (11 papers), Helicobacter pylori-related gastroenterology studies (9 papers), Infant Nutrition and Health (8 papers), Cancer Research and Treatments (8 papers), Diabetes and associated disorders (7 papers), Diabetes Management and Research (6 papers) and Bacterial Genetics and Biotechnology (6 papers). The work is most often cited by research in Food Science (1.7k citations), Biotechnology (681 citations), Nutrition and Dietetics (757 citations), Genetics (1.3k citations) and Infectious Diseases (854 citations). Lothar Steidler has collaborated with scholars based in Belgium, Ireland and United States. Frequent co-authors include Erik Remaut, Sabine Neirynck, Pieter Rottiers, Wolfgang Hans, Walter Fiers, Florian Obermeier, Werner Falk, Nathalie Huyghebaert, Klaas Vandenbroucke and E. Remaut. Their work appears in journals such as Applied and Environmental Microbiology, Gastroenterology, Biotechnology and Bioengineering, Diabetes and Annals of the New York Academy of Sciences.

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