Lingling Xian

2.9k total citations · 1 hit paper
31 papers, 1.5k citations indexed

About

Lingling Xian is a scholar working on Molecular Biology, Oncology and Cancer Research. According to data from OpenAlex, Lingling Xian has authored 31 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 10 papers in Oncology and 9 papers in Cancer Research. Recurrent topics in Lingling Xian's work include Bone Metabolism and Diseases (5 papers), Mesenchymal stem cell research (4 papers) and Bone health and treatments (3 papers). Lingling Xian is often cited by papers focused on Bone Metabolism and Diseases (5 papers), Mesenchymal stem cell research (4 papers) and Bone health and treatments (3 papers). Lingling Xian collaborates with scholars based in United States, China and Hong Kong. Lingling Xian's co-authors include Xu Cao, Janet L. Crane, Mei Wan, Tao Qiu, Xiangwei Wu, Frank J. Frassica, Lijuan Pang, Clifford J. Rosen, Shouhong Xuan and Liming Zhang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Clinical Investigation and Nature Medicine.

In The Last Decade

Lingling Xian

29 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells

2012 507 citations Lingling Xian, Xiangwei Wu et al. Nature Medicine profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lingling Xian United States	17	805	424	269	206	187	31	1.5k
Weiqi Lei United States	10	805 1.0×	429 1.0×	154 0.6×	220 1.1×	199 1.1×	11	1.6k
Nagako Akeno United States	19	932 1.2×	464 1.1×	390 1.4×	171 0.8×	160 0.9×	30	2.1k
Hongming Zhou China	15	869 1.1×	436 1.0×	309 1.1×	107 0.5×	80 0.4×	30	1.6k
M. Piemontese Italy	18	956 1.2×	417 1.0×	192 0.7×	86 0.4×	318 1.7×	31	1.7k
Yuki Matsushita Japan	21	880 1.1×	424 1.0×	285 1.1×	325 1.6×	71 0.4×	76	1.8k
Martine Deckers Netherlands	12	1.0k 1.3×	495 1.2×	225 0.8×	218 1.1×	125 0.7×	18	1.9k
Andrew M. Ho United States	13	715 0.9×	240 0.6×	157 0.6×	162 0.8×	153 0.8×	16	1.7k
Eric Hesse Germany	24	1.3k 1.6×	484 1.1×	436 1.6×	144 0.7×	372 2.0×	64	2.2k
Steve Stegen Belgium	20	906 1.1×	299 0.7×	605 2.2×	221 1.1×	121 0.6×	32	1.9k
Yi Shuai China	18	921 1.1×	164 0.4×	463 1.7×	423 2.1×	130 0.7×	44	1.5k

Countries citing papers authored by Lingling Xian

Since Specialization

Citations

This map shows the geographic impact of Lingling Xian's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lingling Xian with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lingling Xian more than expected).

Fields of papers citing papers by Lingling Xian

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lingling Xian. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lingling Xian. The network helps show where Lingling Xian may publish in the future.

Co-authorship network of co-authors of Lingling Xian

This figure shows the co-authorship network connecting the top 25 collaborators of Lingling Xian. A scholar is included among the top collaborators of Lingling Xian based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lingling Xian. Lingling Xian is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Luo, Li, Jung‐Hyun Kim, Iliana Herrera, et al.. (2025). HMGA1 acts as an epigenetic gatekeeper of ASCL2 and Wnt signaling during colon tumorigenesis. Journal of Clinical Investigation. 135(3). 2 indexed citations

2.

Xian, Lingling, et al.. (2024). Metastatic Ovarian Serous Adenocarcinoma Clinically Presenting as Inflammatory Breast Cancer. SHILAP Revista de lepidopterología. 2024. 1–5.

3.

Yu, Huimin, Zixin Zhang, Lingling Xian, et al.. (2022). Adipokine C1q/Tumor Necrosis Factor- Related Protein 3 (CTRP3) Attenuates Intestinal Inflammation Via Sirtuin 1/NF-κB Signaling. Cellular and Molecular Gastroenterology and Hepatology. 15(4). 1000–1015. 8 indexed citations

4.

Xian, Lingling, Lionel Chia, Dan Georgess, et al.. (2019). Genetic Engineering of Primary Mouse Intestinal Organoids Using Magnetic Nanoparticle Transduction Viral Vectors for Frozen Sectioning. Journal of Visualized Experiments. 10 indexed citations

5.

Gorbounov, Mikhail, Neil Carleton, Lingling Xian, et al.. (2019). High mobility group A1 (HMGA1) protein and gene expression correlate with ER-negativity and poor outcomes in breast cancer. Breast Cancer Research and Treatment. 179(1). 25–35. 17 indexed citations

6.

Xian, Lingling, Lionel Chia, Dan Georgess, et al.. (2019). Genetic Engineering of Primary Mouse Intestinal Organoids Using Magnetic Nanoparticle Transduction Viral Vectors for Frozen Sectioning. Journal of Visualized Experiments. 8 indexed citations

7.

Resar, Linda, Lionel Chia, & Lingling Xian. (2018). Lessons from the Crypt: HMGA1—Amping up Wnt for Stem Cells and Tumor Progression. Cancer Research. 78(8). 1890–1897. 48 indexed citations

8.

Qiu, Tao, Janet L. Crane, Liang Xie, et al.. (2018). IGF-I induced phosphorylation of PTH receptor enhances osteoblast to osteocyte transition. Bone Research. 6(1). 5–5. 45 indexed citations

9.

Xian, Lingling, Dan Georgess, Tait Huso, et al.. (2017). HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche. Nature Communications. 8(1). 15008–15008. 64 indexed citations

10.

Hillion, Jöelle, Sujayita Roy, Mohammad Heydarian, et al.. (2016). The High Mobility Group A1 ( HMGA1 ) gene is highly overexpressed in human uterine serous carcinomas and carcinosarcomas and drives Matrix Metalloproteinase-2 ( MMP-2 ) in a subset of tumors. Gynecologic Oncology. 141(3). 580–587. 27 indexed citations

11.

Zhang, Yunhua, Shujun Zhang, Lingling Xian, et al.. (2015). Expression and purification of recombinant human neuritin from Pichia pastoris and a partial analysis of its neurobiological activity in vitro. Applied Microbiology and Biotechnology. 99(19). 8035–8043. 23 indexed citations

12.

Williams, Michael D., Xing Zhang, Amy Belton, et al.. (2015). HMGA1 Drives Metabolic Reprogramming of Intestinal Epithelium during Hyperproliferation, Polyposis, and Colorectal Carcinogenesis. Journal of Proteome Research. 14(3). 1420–1431. 31 indexed citations

13.

Crane, Janet L., Lingling Xian, & Xu Cao. (2015). Role of TGF-β Signaling in Coupling Bone Remodeling. Methods in molecular biology. 1344. 287–300. 73 indexed citations

14.

Zhang, Hongwei, Lingling Xian, Zhiyi Lin, et al.. (2014). Endothelial progenitor cells as a possible component of stem cell niche to promote self-renewal of mesenchymal stem cells. Molecular and Cellular Biochemistry. 397(1-2). 235–243. 11 indexed citations

15.

Rushworth, Stuart A., Lyubov Zaitseva, Lingling Xian, Kristian M. Bowles, & Linda Resar. (2014). High Mobility Group A1 (HMGA1) Chromatin Remodeling Protein Mediates Crosstalk Between Acute Myeloid Leukemia Blasts & the Tumor Microenvironment. Blood. 124(21). 3564–3564. 1 indexed citations

16.

Xian, Lingling, Xiangwei Wu, Lijuan Pang, et al.. (2012). Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells. Nature Medicine. 18(7). 1095–1101. 507 indexed citations breakdown →

17.

Yu, Bing, Xiaoli Zhao, Chaozhe Yang, et al.. (2012). Parathyroid hormone induces differentiation of mesenchymal stromal/stem cells by enhancing bone morphogenetic protein signaling. Journal of Bone and Mineral Research. 27(9). 2001–2014. 119 indexed citations

18.

Zhao, Jing, Chenji Wang, Jia Wang, et al.. (2011). E3 ubiquitin ligase Siah-1 facilitates poly-ubiquitylation and proteasomal degradation of the hepatitis B viral X protein. FEBS Letters. 585(19). 2943–2950. 43 indexed citations

19.

Peng, Bo, Lihuan Cao, Wenzhang Wang, et al.. (2009). Polymorphisms in the promoter regions of matrix metalloproteinases 1 and 3 and cancer risk: a meta-analysis of 50 case–control studies. Mutagenesis. 25(1). 41–48. 36 indexed citations

20.

Xian, Lingling, Jing Zhao, Jia Wang, et al.. (2009). p53 Promotes proteasome-dependent degradation of oncogenic protein HBx by transcription of MDM2. Molecular Biology Reports. 37(6). 2935–2940. 30 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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