Shoshana Yakar

17.9k total citations · 6 hit papers
172 papers, 13.7k citations indexed

About

Shoshana Yakar is a scholar working on Endocrinology, Diabetes and Metabolism, Molecular Biology and Cancer Research. According to data from OpenAlex, Shoshana Yakar has authored 172 papers receiving a total of 13.7k indexed citations (citations by other indexed papers that have themselves been cited), including 119 papers in Endocrinology, Diabetes and Metabolism, 111 papers in Molecular Biology and 37 papers in Cancer Research. Recurrent topics in Shoshana Yakar's work include Growth Hormone and Insulin-like Growth Factors (112 papers), Metabolism, Diabetes, and Cancer (67 papers) and Cancer, Hypoxia, and Metabolism (29 papers). Shoshana Yakar is often cited by papers focused on Growth Hormone and Insulin-like Growth Factors (112 papers), Metabolism, Diabetes, and Cancer (67 papers) and Cancer, Hypoxia, and Metabolism (29 papers). Shoshana Yakar collaborates with scholars based in United States, Israel and Canada. Shoshana Yakar's co-authors include Derek LeRoith, Derek LeRoith, Jun‐Li Liu, Andrew A. Butler, Clifford J. Rosen, Derek Le Roith, Pnina Brodt, Bethel Stannard, Jennifer Setser and Amir Samani and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Shoshana Yakar

167 papers receiving 13.4k citations

Hit Papers

Normal growth and development in the absence of hepatic i... 1999 2026 2008 2017 1999 2001 2007 2002 2002 250 500 750 1000
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Normal growth and development in the absence of hepatic insulin-like growth factor I
    1999 1.2k citations Shoshana Yakar, Jun‐Li Liu et al. Proceedings of the National Academy of Sciences profile →
  2. The Somatomedin Hypothesis: 2001
    2001 975 citations Derek Le Roith, Carolyn A. Bondy et al. Endocrine Reviews profile →
  3. The Role of the IGF System in Cancer Growth and Metastasis: Overview and Recent Insights
    2007 808 citations Shoshana Yakar, Derek LeRoith et al. Endocrine Reviews profile →
  4. Circulating levels of IGF-1 directly regulate bone growth and density
    2002 703 citations Shoshana Yakar, Clifford J. Rosen et al. Journal of Clinical Investigation profile →
  5. Circulating levels of IGF-1 directly regulate bone growth and density
    2002 604 citations Shoshana Yakar, Clifford J. Rosen et al. Journal of Clinical Investigation profile →
  6. Matrix IGF-1 maintains bone mass by activation of mTOR in mesenchymal stem cells
    2012 507 citations Clifford J. Rosen, Shoshana Yakar et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Shoshana Yakar United States 61 6.9k 6.8k 2.4k 2.1k 2.1k 172 13.7k
Cheryl A. Conover United States 63 6.8k 1.0× 5.9k 0.9× 1.6k 0.7× 1.7k 0.8× 2.3k 1.1× 239 13.8k
Derek LeRoith United States 64 9.3k 1.4× 8.0k 1.2× 1.7k 0.7× 2.4k 1.1× 2.4k 1.1× 181 16.1k
Peter Rotwein United States 60 7.2k 1.0× 8.0k 1.2× 1.2k 0.5× 3.2k 1.5× 1.7k 0.8× 196 13.5k
Robert C. Baxter Australia 78 16.0k 2.3× 10.4k 1.5× 2.3k 1.0× 3.3k 1.5× 4.4k 2.1× 397 22.9k
Raymond L. Hintz United States 66 9.4k 1.4× 4.8k 0.7× 2.0k 0.8× 3.5k 1.7× 906 0.4× 282 15.0k
E. R. Froesch Switzerland 62 7.9k 1.2× 5.4k 0.8× 1.9k 0.8× 2.1k 1.0× 1.3k 0.6× 198 12.1k
David R. Clemmons United States 87 20.4k 3.0× 12.1k 1.8× 4.1k 1.7× 4.6k 2.1× 4.4k 2.1× 344 30.2k
Louis E. Underwood United States 64 8.9k 1.3× 3.9k 0.6× 2.8k 1.2× 2.6k 1.2× 755 0.4× 176 13.6k
Terry G. Unterman United States 62 2.6k 0.4× 7.3k 1.1× 2.5k 1.0× 1.2k 0.6× 1.3k 0.6× 157 12.6k
Etsuro Ogata Japan 57 1.9k 0.3× 5.6k 0.8× 1.6k 0.7× 1.6k 0.7× 573 0.3× 459 12.6k

Countries citing papers authored by Shoshana Yakar

Since Specialization
Citations

This map shows the geographic impact of Shoshana Yakar's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Shoshana Yakar with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Shoshana Yakar more than expected).

Fields of papers citing papers by Shoshana Yakar

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Shoshana Yakar. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Shoshana Yakar. The network helps show where Shoshana Yakar may publish in the future.

Co-authorship network of co-authors of Shoshana Yakar

This figure shows the co-authorship network connecting the top 25 collaborators of Shoshana Yakar. A scholar is included among the top collaborators of Shoshana Yakar based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Shoshana Yakar. Shoshana Yakar is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Sullivan, Ryan, Katherine Gurdziel, Seongho Kim, et al.. (2025). Canagliflozin Reprograms the Aging Hippocampus in Genetically Diverse UM ‐ HET 3 Mice and Attenuates Alzheimer's‐Like Pathology. Aging Cell. 24(12). e70255–e70255. 1 indexed citations
2.
Bromage, Timothy G., Christiane Denys, Hediye Erdjument‐Bromage, et al.. (2025). Palaeometabolomes yield biological and ecological profiles at early human sites. Nature. 649(8099). 1197–1205.
3.
Gong, Zhenwei, Manisha Dixit, Zhiming He, et al.. (2024). Deletion of absent in melanoma-2 (AIM2) drives bone marrow adipogenesis and impairs bone microarchitecture. GeroScience. 47(1). 795–807.
4.
Poudel, Sher Bahadur, Ryan Richard Ruff, Manisha Dixit, et al.. (2024). Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging. Aging. 16(6). 4948–4964. 5 indexed citations
5.
Poudel, Sher Bahadur, Ryan Richard Ruff, Manisha Dixit, et al.. (2023). Excess Growth Hormone Triggers Inflammation-Associated Arthropathy, Subchondral Bone Loss, and Arthralgia. American Journal Of Pathology. 193(6). 829–842. 7 indexed citations
6.
Fujimoto, Masanobu, Melissa Andrew, Dongsheng Zhang, et al.. (2019). Low IGF-I Bioavailability Impairs Growth and Glucose Metabolism in a Mouse Model of Human PAPPA2 p.Ala1033Val Mutation. Endocrinology. 160(6). 1363–1376. 14 indexed citations
7.
Nagaraj, Karthik, Rive Sarfstein, David Gurwitz, et al.. (2018). Identification of thioredoxin-interacting protein (TXNIP) as a downstream target for IGF1 action. Proceedings of the National Academy of Sciences. 115(5). 1045–1050. 49 indexed citations
8.
Gong, Zhenwei, Emir Tas, Shoshana Yakar, & Radhika Muzumdar. (2016). Hepatic lipid metabolism and non-alcoholic fatty liver disease in aging. Molecular and Cellular Endocrinology. 455. 115–130. 112 indexed citations
9.
Kennedy, Oran D., Hui Sun, Yingjie Wu, et al.. (2013). Reductions in serum IGF ‐1 during aging impair health span. Aging Cell. 13(3). 408–418. 62 indexed citations
10.
Wu, Yingjie, Pnina Brodt, Hui Sun, et al.. (2010). Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis. Cancer Research. 70(1). 57–67. 74 indexed citations
11.
Novosyadlyy, Ruslan, Archana Vijayakumar, Anne Rowzee, et al.. (2010). Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes. Cancer Research. 70(2). 741–751. 219 indexed citations
12.
Turner, Russell T., Donald Β. Jump, Carmen P. Wong, et al.. (2009). Growth hormone regulates the balance between bone formation and bone marrow adiposity. Journal of Bone and Mineral Research. 25(4). 757–768. 113 indexed citations
13.
Shukla, Vivek, Xavier Coumoul, Liu Cao, et al.. (2006). Absence of the Full-Length Breast Cancer–Associated Gene-1 Leads to Increased Expression of Insulin-Like Growth Factor Signaling Axis Members. Cancer Research. 66(14). 7151–7157. 36 indexed citations
14.
Olivo‐Marston, Susan, Stephen D. Hursting, Shoshana Yakar, Susan N. Perkins, & Curtis C. Harris. (2006). Genetic reduction of circulating insulin-like growth factor (IGF)-1 inhibits azoxymethane-induced colon tumorigenesis in mice.. Cancer Epidemiology and Prevention Biomarkers. 15. 1 indexed citations
15.
Héron‐Milhavet, Lisa, Martin Haluzı́k, Shoshana Yakar, et al.. (2004). Muscle-Specific Overexpression of CD36 Reverses the Insulin Resistance and Diabetes of MKR Mice. Endocrinology. 145(10). 4667–4676. 56 indexed citations
16.
Yakar, Shoshana, P. Pennisi, Hong Zhao, Yang Zhang, & Derek LeRoith. (2004). Circulating IGF‐1 and Its Role in Cancer: Lessons from the IGF‐1 Gene Deletion (LID) Mouse. Novartis Foundation symposium. 262. 3–18. 19 indexed citations
17.
Yakar, Shoshana, Jennifer Setser, Hong Zhao, et al.. (2004). Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1–deficient mice. Journal of Clinical Investigation. 113(1). 96–105. 187 indexed citations
18.
Yakar, Shoshana, Jennifer Setser, Hong Zhao, et al.. (2004). Inhibition of growth hormone action improves insulin sensitivity in liver IGF-1–deficient mice. Journal of Clinical Investigation. 113(1). 96–105. 164 indexed citations
19.
Yakar, Shoshana, Clifford J. Rosen, Wesley G. Beamer, et al.. (2002). Circulating levels of IGF-1 directly regulate bone growth and density. Journal of Clinical Investigation. 110(6). 771–781. 52 indexed citations
20.
Roith, Derek Le, Carolyn A. Bondy, Shoshana Yakar, Jun‐Li Liu, & Andrew A. Butler. (2001). The Somatomedin Hypothesis: 2001. Endocrine Reviews. 22(1). 53–74. 975 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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