Lewis T. Williams

25.8k citations

114 papers · 22.0k indexed · 12 hit papers · h-index 65

Molecular Biology top 0.1%
Immunology top 0.2%
Oncology top 0.5%
Cell Biology top 0.1%
Cancer Research top 0.5%

Co-authors: Jaime A. Escobedo Daniel E. Johnson Anke Klippel Wendy J. Fantl W. Michael Kavanaugh Michael D. Gunn Carlie de Vries Christoph Reinhard
Topics: Protein Kinase Regulation and GTPase Signaling (36 papers)PI3K/AKT/mTOR signaling in cancer (17 papers)Fibroblast Growth Factor Research (13 papers)
Cited by: Immunology and Allergy Molecular Biology Immunology
Journals: Nature Science Cell
Partner nations: United States Japan United Kingdom

In The Last Decade

Lewis T. Williams

113 papers receiving 21.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The fms -Like Tyrosine Kinase, a Receptor for Vascular Endothelial Growth Factor

1992 1.7k citations Jaime A. Escobedo, Lewis T. Williams et al. profile →
Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 1.1k citations Lewis T. Williams et al. profile →
Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

1997 1.0k citations Christoph Reinhard, Anke Klippel et al. profile →
Mice Lacking Expression of Secondary Lymphoid Organ Chemokine Have Defects in Lymphocyte Homing and Dendritic Cell Localization

1999 841 citations Lewis T. Williams et al. profile →
A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes

1998 804 citations Lewis T. Williams et al. profile →
A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1

1998 674 citations Lewis T. Williams et al. profile →
Discovery of a Cytokine and Its Receptor by Functional Screening of the Extracellular Proteome

2008 615 citations Haishan Lin, Kevin Hestir et al. profile →
Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways

1992 588 citations Wendy J. Fantl, Jaime A. Escobedo et al. Cell profile →
Purification and Complementary DNA Cloning of a Receptor for Basic Fibroblast Growth Factor

1989 578 citations Lewis T. Williams et al. profile →
Signal Transduction by the Platelet-Derived Growth Factor Receptor

1989 575 citations Lewis T. Williams profile →
PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1990 503 citations David R. Kaplan, Deborah K. Morrison et al. Cell profile →
Role of Phosphatidylinositol Kinase in PDGF Receptor Signal Transduction

1989 467 citations Jaime A. Escobedo, Lewis T. Williams et al. profile →

Peers

Countries citing papers authored by Lewis T. Williams

Since Specialization

Citations

This map shows the geographic impact of Lewis T. Williams's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lewis T. Williams with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lewis T. Williams more than expected).

Fields of papers citing papers by Lewis T. Williams

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lewis T. Williams. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lewis T. Williams. The network helps show where Lewis T. Williams may publish in the future.

Co-authorship network of co-authors of Lewis T. Williams

This figure shows the co-authorship network connecting the top 25 collaborators of Lewis T. Williams. A scholar is included among the top collaborators of Lewis T. Williams based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lewis T. Williams. Lewis T. Williams is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A highly photostable and versatile two-photon fluorescent probe for the detection of a wide range of intracellular nitric oxide concentrations in macrophages and endothelial cells 2022 ·Journal of Photochemistry and Photobiology B Biology ·(unknown),Lewis T. Williams,Paul Thomas,Robert T. Johnson,(unknown),Derek Warren,Anastasia Sobolewski,María Paz Muñoz,Francisco Galindo,María J. Marín	11
2	Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells 2010 ·Journal of Leukocyte Biology ·Suwen Wei,Sayan Nandi,Violeta Chiţu,Yee-Guide Yeung,Wenfeng Yu,(unknown),Lewis T. Williams,Haishan Lin,E. Richard Stanley	289
3	A generation of change, a lifetime of difference? 2009 ·Bristol University Press eBooks ·Martin Evans,Lewis T. Williams	2
4	FP-1039 (FGFR1:Fc), a soluble FGFR1 receptor antagonist, inhibits tumor growth and angiogenesis 2007 ·Molecular Cancer Therapeutics ·Hongbing Zhang,(unknown),Kevin P. Baker,Ali Sadra,Elizabeth Bosch,(unknown),Stephen K. Doberstein,(unknown),Kevin Hestir,Diane Hollenbaugh,(unknown),Minmin Qin,Lewis T. Williams	11
5	Fibroblast growth factor receptor 1-IIIb is dispensable for skin morphogenesis and wound healing 2004 ·European Journal of Cell Biology ·Hongbing Zhang,Jessica Sordet‐Dessimoz,Tobias A. Beyer,Monika Krampert,Lewis T. Williams,Sabine Werner,Richard Grose	16
6	Regulation of the MAP kinase pathway by mammalian Ksr through direct interaction with MEK and ERK 1998 ·Current Biology ·Wei Yu,Wendy J. Fantl,Greg Harrowe,Lewis T. Williams	169
7	Inhibition of mSOS-activity by binding of phosphatidylinositol 4,5-P2 to the mSOS pleckstrin homology domain 1998 ·Oncogene ·Anne B. Jefferson,Anke Klippel,Lewis T. Williams	16
8	Early Activation of c-Jun N-terminal Kinase and p38 Kinase Regulate Cell Survival in Response to Tumor Necrosis Factor α 1998 ·Journal of Biological Chemistry ·Anne Roulston,Christoph Reinhard,Payman Amiri,Lewis T. Williams	351
9	CPAN, a human nuclease regulated by the caspase-sensitive inhibitor DFF45 1998 ·Current Biology ·Robert Halenbeck,H. Robson MacDonald,Anne Roulston,Tseng-hui Timothy Chen,Leah Conroy,Lewis T. Williams	182
10	A Specific Product of Phosphatidylinositol 3-Kinase Directly Activates the Protein Kinase Akt through Its Pleckstrin Homology Domain 1997 ·Molecular and Cellular Biology ·Anke Klippel,W. Michael Kavanaugh,David Pot,Lewis T. Williams	423
11	Regulation of Interaction of ras p21 with RalGDS and Raf-1 by Cyclic AMP-dependent Protein Kinase 1996 ·Journal of Biological Chemistry ·Akira Kikuchi,Lewis T. Williams	60
12	Regulation of Raf-1-Dependent Signaling during Early Xenopus Development 1995 ·Molecular and Cellular Biology ·Angus M. MacNicol,Anthony J. Muslin,Emily L. Howard,Akira Kikuchi,Melanie C MacNicol,Lewis T. Williams	26
13	ralGDS Family Members Interact with the Effector Loop of ras p21 1994 ·Molecular and Cellular Biology ·Akira Kikuchi,Susan D. Demo,(unknown),Yen‐Wen Chen,Lewis T. Williams	47
14	Raf-1 Protein Kinase Is Important for Progesterone-Induced Xenopus Oocyte Maturation and Acts Downstream of mos 1993 ·Molecular and Cellular Biology ·Anthony J. Muslin,Angus M. MacNicol,Lewis T. Williams	22
15	Platelet-Derived Growth Factor Receptor Mediates Activation of Ras through Different Signaling Pathways in Different Cell Types 1993 ·Molecular and Cellular Biology ·Takaya Satoh,Wendy J. Fantl,Jaime A. Escobedo,Lewis T. Williams,Yoshito Kaziro	12
16	Raf-1 kinase is essential for early Xenopus development and mediates the induction of mesoderm by FGF 1993 ·Cell ·Angus M. MacNicol,Anthony J. Muslin,Lewis T. Williams	179
17	Modification of the 85-Kilodalton Subunit of Phosphatidylinositol-3 Kinase in Platelet-Derived Growth Factor-Stimulated Cells 1992 ·Molecular and Cellular Biology ·W. Michael Kavanaugh,Anke Klippel,Jaime A. Escobedo,Lewis T. Williams	20
18	A Phosphatidylinositol-3 Kinase Binds to Platelet-Derived Growth Factor Receptors through a Specific Receptor Sequence Containing Phosphotyrosine 1991 ·Molecular and Cellular Biology ·Jaime A. Escobedo,David R. Kaplan,W. Michael Kavanaugh,Christoph W. Turck,Lewis T. Williams	257
19	PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complexbreakdown → 1990 ·Cell ·David R. Kaplan,Deborah K. Morrison,Gail A. Wong,Frank McCormick,Lewis T. Williams	503
20	Role of Tyrosine Kinase and Membrane-Spanning Domains in Signal Transduction by the Platelet-Derived Growth Factor Receptor 1988 ·Molecular and Cellular Biology ·(unknown),Philip J. Barr,Lewis T. Williams	32

About Lewis T. Williams

Lewis T. Williams is a scholar working on Molecular Biology, Cell Biology and Oncology, having authored 114 papers that have together received 22.0k indexed citations. Recurring topics across this work include Protein Kinase Regulation and GTPase Signaling (36 papers), PI3K/AKT/mTOR signaling in cancer (17 papers) and Fibroblast Growth Factor Research (13 papers). The work is most often cited by research in Immunology and Allergy (1.5k citations), Molecular Biology (15.2k citations) and Immunology (4.6k citations). Lewis T. Williams has collaborated with scholars based in United States, Japan and United Kingdom. Frequent co-authors include Jaime A. Escobedo, Daniel E. Johnson, Anke Klippel, Wendy J. Fantl, W. Michael Kavanaugh, Michael D. Gunn, Carlie de Vries, Christoph Reinhard, Hikaru Ueno and Shaun R. Coughlin. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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