Leighton Coates

4.6k citations

113 papers · 3.0k indexed · 1 hit paper · h-index 33

Impact in

Computational Theory and Mathematics top 0.5%
- Computational Drug Discovery Methods
Infectious Diseases top 2%
- SARS-CoV-2 and COVID-19 Research

Papers in

Molecular Medicine 9
Radiation 14
- Nuclear Physics and Applications 14

Co-authors: Andrey Kovalevsky Kevin L. Weiss Daniel W. Kneller Paul Langan P.T. Erskine J.B. Cooper G.N. Phillips Hugh O’Neill
Journals: Acta Crystallographica Section D Structural Biology (8 papers)Journal of Molecular Biology (7 papers)Nature Communications (6 papers)Journal of Medicinal Chemistry (5 papers)Biochemistry (5 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

Leighton Coates

110 papers receiving 3.0k citations

Hit Papers

align trajectories log scale

Structural plasticity of SARS-CoV-2 3CL Mpro active site cavity revealed by room temperature X-ray crystallography 2020 · 338 citations

Peers

Countries citing papers authored by Leighton Coates

Since Specialization

Citations

This map shows the geographic impact of Leighton Coates's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leighton Coates with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leighton Coates more than expected).

Fields of papers citing papers by Leighton Coates

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leighton Coates. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leighton Coates. The network helps show where Leighton Coates may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Leighton Coates, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Leighton Coates Line = papers co-authored together Leighton Coates links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Backbone assignment of a 28.5 kDa class A extended spectrum β-lactamase by high-field, carbon-detected solid-state NMR Biomolecular NMR Assignments ·Magdalena Łomzik, Songlin Wang, Richard Meeks, Meihui Tian, Makoto Yamashiki, Leighton Coates, Chad M. Rienstra, Leonard J. Mueller	2025	0
2	Contribution of the catalytic dyad of SARS-CoV-2 main protease to binding covalent and noncovalent inhibitors Journal of Biological Chemistry ·Andrey Kovalevsky, Annie Aniana, Leighton Coates, Peter V. Bonnesen, Nashaat T. Nashed, John M. Louis	2023	16
3	The mechanisms of catalysis and ligand binding for the SARS-CoV-2 NSP3 macrodomain from neutron and x-ray diffraction at room temperature Science Advances ·G.J. Correy, Daniel W. Kneller, G.N. Phillips, Swati Pant, Silvia Russi, Aina E. Cohen, G. Meigs, James M. Holton, Stefan Gahbauer, Michael C. Thompson, Alan Ashworth, Leighton Coates, Andrey Kovalevsky, Flora Meilleur, James S. Fraser	2022	24
4	Cryo neutron crystallography demonstrates influence of RNA 2′-OH orientation on conformation, sugar pucker and water structure Nucleic Acids Research ·Joel M. Harp, Terry P. Lybrand, Pradeep S. Pallan, Leighton Coates, Brendan Sullivan, Martin Egli	2022	6
5	EWALD: A macromolecular diffractometer for the second target station Review of Scientific Instruments ·(unknown), William B. O’Dell, Martin Egli, Jan Kern, Andrey Kovalevsky, Jiao Lin, Dean A. A. Myles, Mark A. Wilson, Wen Zhang, Petrus H. Zwart, Leighton Coates	2022	3
6	Conformational Dynamics in the Interaction of SARS-CoV-2 Papain-like Protease with Human Interferon-Stimulated Gene 15 Protein The Journal of Physical Chemistry Letters ·S P Gale, Kevin L. Weiss, G.N. Phillips, 有田好之, Shuo Qian, Susan E. Tsutakawa, Leighton Coates, Hugh O’Neill	2021	10
7	Michaelis-like complex of SARS-CoV-2 main protease visualized by room-temperature X-ray crystallography IUCrJ ·Daniel W. Kneller, Qiu Zhang, Leighton Coates, John M. Louis, Andrey Kovalevsky	2021	26
8	Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography Journal of Medicinal Chemistry ·Daniel W. Kneller, G.N. Phillips, Kevin L. Weiss, Qiu Zhang, Leighton Coates, Andrey Kovalevsky	2021	43
9	Probing the role of the conserved residue Glu166 in a class A β-lactamase using neutron and X-ray protein crystallography Acta Crystallographica Section D Structural Biology ·Uli Syré, Brendan Sullivan, Kevin L. Weiss, Leighton Coates	2020	2
10	The structure of a potassium-selective ion channel reveals a hydrophobic gate regulating ion permeation IUCrJ ·Uli Syré, Venu Gopal Vandavasi, Wojciech Kopeć, Brendan Sullivan, Ю.Р. Сидорик, Kevin L. Weiss, Bert L. de Groot, Leighton Coates	2020	6
11	BraggNet: integrating Bragg peaks using neural networks Journal of Applied Crystallography ·Brendan Sullivan, Richard Archibald, Jahaun Azadmanesh, Venu Gopal Vandavasi, Uli Syré, Leighton Coates, V. E. Lynch, Paul Langan	2019	29
12	Defining the Specificity of Carbohydrate–Protein Interactions by Quantifying Functional Group Contributions Journal of Chemical Information and Modeling ·Amika Sood, Oksana Gerlits, Ye Ji, Nicolai V. Bovin, Leighton Coates, Robert J. Woods	2018	20
13	Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design Journal of Medicinal Chemistry ·Maja Kovačević, Jeong Hyo Bae, Tobias E. Schrader, Andreas Ostermann, Leighton Coates, Mikael Akke, Matthew P. Blakeley, Esko Oksanen, Derek T. Logan	2018	32
14	Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG) Acta Crystallographica Section F Structural Biology Communications ·Joel M. Harp, Leighton Coates, Brendan Sullivan, Martin Egli	2018	5
15	Preliminary neutron diffraction analysis of challenging human manganese superoxide dismutase crystals Acta Crystallographica Section F Structural Biology Communications ·Jahaun Azadmanesh, 仁雄中野, Kevin L. Weiss, Leighton Coates, (unknown)	2017	17
16	Protein crystallization and initial neutron diffraction studies of the photosystem II subunit PsbO Acta Crystallographica Section F Structural Biology Communications ·Martin Bommer, Leighton Coates, Holger Dau, Athina Zouni, Holger Dobbek	2017	5
17	Perdeuteration, crystallization, data collection and comparison of five neutron diffraction data sets of complexes of human galectin-3C Acta Crystallographica Section D Structural Biology ·Maja Kovačević, K. Saraboji, Janina Sprenger, 贾志洋, 李富廷, Ulf J. Nilsson, Hakon Leffler, S. Zoë Fisher, Tobias E. Schrader, Andreas Ostermann, Leighton Coates, Matthew P. Blakeley, Esko Oksanen, Derek T. Logan	2016	15
18	Structural studies of substrate and product complexes of 5-aminolaevulinic acid dehydratase from humans,Escherichia coliand the hyperthermophilePyrobaculum calidifontis Acta Crystallographica Section D Structural Biology ·E Matsumura, Danica Butler, Christine Lowe, Darren A. Thompson, Mohammed G. Sarwar, Jingxu Guo, Raj Gill, A. E. Batayeva, Alun R. Coker, Steve Wood, P.T. Erskine, Leighton Coates, J.B. Cooper, Naeem Rashid, Muhammad Akhtar, Peter M. Shoolingin‐Jordan	2016	24
19	Neutron and high-resolution room-temperature X-ray data collection from crystallized lytic polysaccharide monooxygenase Acta Crystallographica Section F Structural Biology Communications ·J.P. Bacik, Sophanit Mekasha, Zarah Forsberg, Andrey Kovalevsky, Jay C. Nix, M.J. Cuneo, Leighton Coates, Gustav Vaaje‐Kolstad, Julian C.‐H. Chen, Vincent G. H. Eijsink, Clifford J. Ünkefer	2015	6
20	Large-volume protein crystal growth for neutron macromolecular crystallography Acta Crystallographica Section F Structural Biology Communications ·Joseph D. Ng, James K. Baird, Leighton Coates, Juan Manuel García‐Ruiz, Олена Вінниченко, Daniela Álvarez Amaral	2015	31

About Leighton Coates

Leighton Coates is a scholar working on Molecular Medicine, Radiation, Materials Chemistry, Molecular Biology and Biophysics, having authored 113 papers that have together received 3.0k indexed citations. Recurring topics across this work include Enzyme Structure and Function (60 papers), Protein Structure and Dynamics (34 papers), Nuclear Physics and Applications (14 papers), RNA and protein synthesis mechanisms (12 papers), Computational Drug Discovery Methods (12 papers), SARS-CoV-2 and COVID-19 Research (11 papers), Biochemical and Molecular Research (10 papers) and Porphyrin Metabolism and Disorders (9 papers). The work is most often cited by research in Computational Theory and Mathematics (669 citations), Infectious Diseases (574 citations), Molecular Biology (1.8k citations), Radiation (221 citations) and Molecular Medicine (123 citations). Leighton Coates has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include Andrey Kovalevsky, Kevin L. Weiss, Daniel W. Kneller, Paul Langan, P.T. Erskine, J.B. Cooper, G.N. Phillips, Hugh O’Neill, Steve Wood and Stephen J. Tomanicek. Their work appears in journals such as Acta Crystallographica Section D Structural Biology, Journal of Molecular Biology, Nature Communications, Journal of Medicinal Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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