Laurent Debüssche

3.9k citations

75 papers · 2.7k indexed · h-index 34

Impact in

Rheumatology top 1%
- Folate and B Vitamins Research
Molecular Biology top 5%
- Porphyrin Metabolism and Disorders
- Biochemical and Molecular Research
- Ubiquitin and proteasome pathways
- Photosynthetic Processes and Mechanisms
- Heme Oxygenase-1 and Carbon Monoxide

Papers in

Rheumatology 25
- Folate and B Vitamins Research 25
Oncology 25
- Cancer-related Molecular Pathways 18

Co-authors: Francis Blanche D Thibaut Béatrice Cameron J Crouzet M Couder Didier Faucher Laurent Bracco Bruno Tocqué
Journals: Journal of Bacteriology (18 papers)Cancer Research (9 papers)Oncogene (6 papers)Molecular and Cellular Biology (3 papers)Clinical Cancer Research (2 papers)
Partner nations: France United States United Kingdom

In The Last Decade

Laurent Debüssche

74 papers receiving 2.6k citations

Peers

Countries citing papers authored by Laurent Debüssche

Since Specialization

Citations

This map shows the geographic impact of Laurent Debüssche's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Laurent Debüssche with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Laurent Debüssche more than expected).

Fields of papers citing papers by Laurent Debüssche

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Laurent Debüssche. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Laurent Debüssche. The network helps show where Laurent Debüssche may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Laurent Debüssche, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Laurent Debüssche Line = papers co-authored together Laurent Debüssche links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Genome-wide CRISPR Screen Reveals RAB10 as a Synthetic Lethal Gene in Colorectal and Pancreatic Cancers Carrying SMAD4 Loss Cancer Research Communications ·Frank B. Byshakra, 彰余田, Frédéric Lacroix, Sukhvinder Sidhu, Shakeel Hussain Chattha, Akimasa Adachi, 段俊平, Isabelle Sanchez, Michelle Faria da Silva, Michel Didier, Laurent Debüssche, Christophe Marcireau	2023	4
2	YAP1 is essential for malignant mesothelioma tumor maintenance BMC Cancer ·Loreley Calvet, Ronen Eckhouse, Emmanuel Spanakis, Fany Nelvana Arse, Jean-Christophe Le Bail, Armelle Buzy, Pascal Paul, Ana Loureiro, S. W. Lee, Colette Dib, Jack Pollard, Sukhvinder Sidhu, Jürgen Moll, Laurent Debüssche, 宁宜宝	2022	12
3	KRAS G12C fragment screening renders new binding pockets Small GTPases ·Magali Mathieu, 香港特別行政區政府統計處, Florence Fassy, Cécile Delorme, 正義久門, Amagoia Alemán, Francis Duffieux, Thomas Bertrand, C. Pagliarone et al., Siti Nurfajriah, Nemanja Rajković, 李志莉 Li Zhili, J.-P. Marquette, Maryse Lowinski, Laura Bruque Calero, 赖华龙, Laurent Debüssche, Alexey Rak	2021	15
4	Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition SLAS DISCOVERY ·Lo Lai, Diane Dees, Kanika Sharma, 京子濱口, A Asquez, Elizabeth Ray, N. Muzet, Igor I. Kochegarov, Renaud Morales, E.K. Rooney, Nicolas Basse, Ming Yi, Frédéric Lacroix, Matthew Holderfield, Walter Englaro, Christophe Marcireau, Laurent Debüssche, Dwight V. Nissley, Frank McCormick	2021	1
5	Synergistic activity and heterogeneous acquired resistance of combined MDM2 and MEK inhibition in KRAS mutant cancers Oncogene ·Aaron N. Hata, Jae-Yoon Jeon, Hannah L. Archibald, María Gomez‐Caraballo, Farzan Siddiqui, Fei Ji, Myungjune Oh, Mark E. Light, Jae‐Sung Lee, Laurent Debüssche, Sukhvinder Sidhu, Ruslan I. Sadreyev, James Watters, Jeffrey A. Engelman	2017	28
6	Prostaglandin EP2 receptor signaling protects human trabecular meshwork cells from apoptosis induced by ER stress through down-regulation of p53 Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·Zhou Bing-quan, Céline Boucher, Kei Yamamoto, Laurent Debüssche, Cécile Orsini, Christophe Baudouin, Thomas Debeir, Xavier Vigé, William Rostène	2016	14
7	Elucidation of Acquired Resistance to Bcl-2 and MDM2 Inhibitors in Acute Leukemia In Vitro and In Vivo Clinical Cancer Research ·C. Gianna Hoffman-Luca, Areli Isabel Martínez Hernández, Donna McEachern, Yujun Zhao, Wei Sun, Laurent Debüssche, Shaomeng Wang	2015	44
8	SAR405838: A Novel and Potent Inhibitor of the MDM2:p53 Axis for the Treatment of Dedifferentiated Liposarcoma Clinical Cancer Research ·Kate Lynn J. Bill, Jeannine Garnett, Isabelle Meaux, R. H. F. van Oppenraaij, Chad J. Creighton, Svetlana Bolshakov, Cédric Barrière, Laurent Debüssche, Alexander J. Lazar, Bethany C. Prudner, Lucia Casadei, Danielle Braggio, Gonzalo Lopez, 田中彰, Hemant K. Bid, Dina Lev, Raphael E. Pollock	2015	86
9	Discovery, Structure Elucidation, and Biological Characterization of Nannocystin A, a Macrocyclic Myxobacterial Metabolite with Potent Antiproliferative Properties Angewandte Chemie International Edition ·Holger Hoffmann, Herbert Kogler, B Dasgupta, Hans Matter, Michael Caspers, Dietmar Schummer, Kojiro Esaki, Armin Bauer, Géraldine Pénarier, Laurent Debüssche, Mark Brönstrup	2015	70
10	Significant Differences in the Development of Acquired Resistance to the MDM2 Inhibitor SAR405838 between In Vitro and In Vivo Drug Treatment PLoS ONE ·C. Gianna Hoffman-Luca, Shengyao Gao, Jianfeng Lü, Areli Isabel Martínez Hernández, Donna McEachern, Laurent Debüssche, Shaomeng Wang	2015	22
11	Inhibition of the Ras-Net (Elk-3) Pathway by a Novel Pyrazole that Affects Microtubules Cancer Research ·Christine Wasylyk, Hong Zheng, Arnaud Mary, Laurent Debüssche, Marie-Christine Multon, Bohdan Wasylyk	2008	72
12	CD45neg but Not CD45pos Human Myeloma Cells Are Sensitive to the Inhibition of IGF-1 Signaling by a Murine Anti-IGF-1R Monoclonal Antibody, mAVE1642 The Journal of Immunology ·Géraldine Descamps, Soraya Wuillème‐Toumi, Valérie Trichet, Corinne Venot, Laurent Debüssche, Thierry Hercend, M. Collette, Nelly Robillard, Régis Bataille, Martine Amiot	2006	32
13	Restoration of transcriptional activity of p53 mutants in human tumour cells by intracellular expression of anti-p53 single chain Fv fragments Oncogene ·Claude Caron de Fromentel, Nadège Gruel, Corinne Venot, Laurent Debüssche, Emmanuel Conseiller, Christine Dureuil, Jean‐Luc Teillaud, Bruno Tocqué, Laurent Bracco	1999	67
14	Calcium-dependent Interaction of S100B with the C-terminal Domain of the Tumor Suppressor p53 Journal of Biological Chemistry ·Christian Delphin, Michel Ronjat, Jean‐Christophe Deloulme, Yue Shi, Laurent Debüssche, Yuichiro Higashimoto, Kazuyasu Sakaguchi, Jacques Baudier	1999	66
15	Definition of a p53 transactivation function-deficient mutant and characterization of two independent p53 transactivation subdomains Oncogene ·Corinne Venot, Lana Župančić, Shuo Li, Emmanuel Conseiller, Laurent Debüssche	1999	60
16	CTS1: a p53-derived chimeric tumor suppressor gene with enhanced in vitro apoptotic properties. Journal of Clinical Investigation ·Emmanuel Conseiller, Laurent Debüssche, D Landais, Corinne Venot, Lana Župančić, Shuo Li, Bruno Tocqué, Laurent Bracco	1998	27
17	Proteolysis by Calpains: a Possible Contribution to Degradation of p53 Molecular and Cellular Biology ·Magali Pariât, Serge Carillo, Marta Molinari, Catherine Salvat, Laurent Debüssche, Laurent Bracco, Jo Milner, Marc Piechaczyk	1997	138
18	Parallelen und maßgebliche Unterschiede bei Vitamin‐B₁₂‐Biosynthesen Angewandte Chemie ·Francis Blanche, Eris Triyani, Laurent Debüssche, Ralf Hertle, H.F. Zappe, Gerhard Müller	1993	3
19	Purification and characterization of S-adenosyl-L-methionine: uroporphyrinogen III methyltransferase from Pseudomonas denitrificans Journal of Bacteriology ·Francis Blanche, Laurent Debüssche, D Thibaut, J Crouzet, Béatrice Cameron	1989	105
20	Antibodies to Synthetic Peptide from the Residue 33 to 42 Domain of c-Ha- ras p21 Block Reconstitution of the Protein with Different Effectors Molecular and Cellular Biology ·J. A. Burnsf, S BOWN, Laurent Debüssche, Claudine David, Anne Morgat, 花田幸典, J F Mayaux, Bruno Tocqué	1989	22

About Laurent Debüssche

Laurent Debüssche is a scholar working on Rheumatology, Oncology, Molecular Biology, Biotechnology and Clinical Biochemistry, having authored 75 papers that have together received 2.7k indexed citations. Recurring topics across this work include Porphyrin Metabolism and Disorders (33 papers), Folate and B Vitamins Research (25 papers), Cancer-related Molecular Pathways (18 papers), Neonatal Health and Biochemistry (9 papers), Biochemical and Molecular Research (7 papers), Enzyme Structure and Function (7 papers), Microbial Natural Products and Biosynthesis (6 papers) and Cancer Research and Treatments (5 papers). The work is most often cited by research in Rheumatology (715 citations), Molecular Biology (2.2k citations), Biotechnology (190 citations), Oncology (512 citations) and Cell Biology (215 citations). Laurent Debüssche has collaborated with scholars based in France, United States and United Kingdom. Frequent co-authors include Francis Blanche, D Thibaut, Béatrice Cameron, J Crouzet, M Couder, Didier Faucher, Laurent Bracco, Bruno Tocqué, Finian J. Leeper and Alan R. Battersby. Their work appears in journals such as Journal of Bacteriology, Cancer Research, Oncogene, Molecular and Cellular Biology and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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