Laura O’Regan

1.7k total citations
21 papers, 1.2k citations indexed

About

Laura O’Regan is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Laura O’Regan has authored 21 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 14 papers in Cell Biology and 6 papers in Oncology. Recurrent topics in Laura O’Regan's work include Microtubule and mitosis dynamics (13 papers), DNA Repair Mechanisms (4 papers) and Cellular transport and secretion (4 papers). Laura O’Regan is often cited by papers focused on Microtubule and mitosis dynamics (13 papers), DNA Repair Mechanisms (4 papers) and Cellular transport and secretion (4 papers). Laura O’Regan collaborates with scholars based in United Kingdom, Spain and South Korea. Laura O’Regan's co-authors include Andrew M. Fry, Richard Bayliss, Sarah Sabir, Joëlle Blot, Mark W. Richards, Jessica M. Montgomery, Anne Straube, Daniel Röth, Dean A. Fennell and Richard D. Kelly and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Laura O’Regan

21 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Laura O’Regan United Kingdom 14 953 479 275 159 137 21 1.2k
Jennifer A. Perry United States 14 1.5k 1.6× 300 0.6× 471 1.7× 173 1.1× 108 0.8× 16 1.8k
Angela Paul United Kingdom 15 913 1.0× 222 0.5× 319 1.2× 123 0.8× 88 0.6× 18 1.3k
Agnes Ang United States 17 763 0.8× 638 1.3× 339 1.2× 144 0.9× 79 0.6× 32 1.4k
Lara Wohlbold Germany 16 1.1k 1.2× 192 0.4× 332 1.2× 89 0.6× 86 0.6× 20 1.4k
Miki Hieda Japan 19 1.1k 1.1× 263 0.5× 228 0.8× 69 0.4× 71 0.5× 37 1.4k
Matthew K. Summers United States 22 1.3k 1.4× 711 1.5× 450 1.6× 95 0.6× 114 0.8× 39 1.6k
Sudharshan Eathiraj United States 16 893 0.9× 597 1.2× 179 0.7× 119 0.7× 76 0.6× 38 1.5k
Lauren M. Zasadil United States 15 884 0.9× 790 1.6× 406 1.5× 72 0.5× 155 1.1× 17 1.3k
Richard J. Austin United States 14 1.1k 1.2× 257 0.5× 340 1.2× 53 0.3× 192 1.4× 22 1.4k
Simone Lieb Austria 6 734 0.8× 452 0.9× 321 1.2× 97 0.6× 47 0.3× 9 995

Countries citing papers authored by Laura O’Regan

Since Specialization
Citations

This map shows the geographic impact of Laura O’Regan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Laura O’Regan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Laura O’Regan more than expected).

Fields of papers citing papers by Laura O’Regan

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Laura O’Regan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Laura O’Regan. The network helps show where Laura O’Regan may publish in the future.

Co-authorship network of co-authors of Laura O’Regan

This figure shows the co-authorship network connecting the top 25 collaborators of Laura O’Regan. A scholar is included among the top collaborators of Laura O’Regan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Laura O’Regan. Laura O’Regan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
O’Regan, Laura, et al.. (2024). Microtubule Association of EML4–ALK V3 Is Key for the Elongated Cell Morphology and Enhanced Migration Observed in V3 Cells. Cells. 13(23). 1954–1954. 1 indexed citations
2.
O’Regan, Laura, Giancarlo Barone, Susan W. Robinson, et al.. (2024). The mesenchymal morphology of cells expressing the EML4–ALK V3 oncogene is dependent on phosphorylation of Eg5 by NEK7. Journal of Biological Chemistry. 300(5). 107144–107144. 3 indexed citations
3.
O’Regan, Laura, Jene Choi, Josephina Sampson, et al.. (2022). EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity. Molecular Cancer Research. 20(6). 854–866. 11 indexed citations
4.
O’Regan, Laura, et al.. (2022). Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes. Biology Open. 11(2). 4 indexed citations
5.
O’Regan, Laura, et al.. (2022). Alternative Treatment Options to ALK Inhibitor Monotherapy for EML4-ALK-Driven Lung Cancer. Cancers. 14(14). 3452–3452. 9 indexed citations
6.
Busacca, Sara, Laura O’Regan, Annabel Sharkey, et al.. (2020). BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma. Molecular Cancer Therapeutics. 20(2). 379–388. 13 indexed citations
7.
Montgomery, Jessica M., Joseph Atherton, Laura O’Regan, et al.. (2019). Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression. Science Signaling. 12(594). 34 indexed citations
8.
Sabir, Sarah, Laura O’Regan, Josephina Sampson, et al.. (2018). Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release. Science Signaling. 11(543). 11 indexed citations
9.
Sampson, Josephina, Laura O’Regan, Martin J.S. Dyer, Richard Bayliss, & Andrew M. Fry. (2017). Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells. Cancer Research. 77(18). 4785–4796. 22 indexed citations
10.
Fry, Andrew M., et al.. (2016). EML proteins in microtubule regulation and human disease. Biochemical Society Transactions. 44(5). 1281–1288. 25 indexed citations
11.
O’Regan, Laura, Josephina Sampson, Mark W. Richards, et al.. (2015). Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression. The Journal of Cell Biology. 209(3). 349–358. 40 indexed citations
12.
Richards, Mark W., Selena G. Burgess, Pablo Gallego, et al.. (2015). Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization. Nature Communications. 6(1). 8771–8771. 45 indexed citations
13.
Prosser, Suzanna L., Laura O’Regan, & Andrew M. Fry. (2015). Novel insights into the mechanisms of mitotic spindle assembly by NEK kinases. Molecular & Cellular Oncology. 3(3). e1062952–e1062952. 13 indexed citations
14.
Richards, Mark W., Laura O’Regan, Daniel Röth, et al.. (2015). Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain. Biochemical Journal. 467(3). 529–536. 69 indexed citations
15.
Kelly, Richard D., Laura O’Regan, Oliver M. Dovey, et al.. (2014). Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells. Proceedings of the National Academy of Sciences. 111(27). 9840–9845. 122 indexed citations
16.
Richards, Mark W., Sara Busacca, Laura O’Regan, et al.. (2014). Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain. Proceedings of the National Academy of Sciences. 111(14). 5195–5200. 75 indexed citations
17.
Fry, Andrew M., Laura O’Regan, Sarah Sabir, & Richard Bayliss. (2012). Cell cycle regulation by the NEK family of protein kinases. Journal of Cell Science. 125(Pt 19). 4423–33. 300 indexed citations
18.
Richards, Mark W., Laura O’Regan, Corine Mas-Droux, et al.. (2009). An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9. Molecular Cell. 36(4). 560–570. 78 indexed citations
19.
O’Regan, Laura & Andrew M. Fry. (2009). The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis. Molecular and Cellular Biology. 29(14). 3975–3990. 134 indexed citations
20.
O’Regan, Laura, Joëlle Blot, & Andrew M. Fry. (2007). Mitotic regulation by NIMA-related kinases. Cell Division. 2(1). 25–25. 169 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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