Laura O’Regan

1.7k total citations
21 papers, 1.2k citations indexed

About

Laura O’Regan is a scholar working on Molecular Biology, Cell Biology and Oncology. According to data from OpenAlex, Laura O’Regan has authored 21 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 14 papers in Cell Biology and 6 papers in Oncology. Recurrent topics in Laura O’Regan's work include Microtubule and mitosis dynamics (13 papers), DNA Repair Mechanisms (4 papers) and Cellular transport and secretion (4 papers). Laura O’Regan is often cited by papers focused on Microtubule and mitosis dynamics (13 papers), DNA Repair Mechanisms (4 papers) and Cellular transport and secretion (4 papers). Laura O’Regan collaborates with scholars based in United Kingdom, Spain and South Korea. Laura O’Regan's co-authors include Andrew M. Fry, Richard Bayliss, Sarah Sabir, Joëlle Blot, Mark W. Richards, Jessica M. Montgomery, Anne Straube, Daniel Röth, Dean A. Fennell and Richard D. Kelly and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Laura O’Regan

21 papers receiving 1.2k citations

Peers

Countries citing papers authored by Laura O’Regan

Since Specialization

Citations

This map shows the geographic impact of Laura O’Regan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Laura O’Regan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Laura O’Regan more than expected).

Fields of papers citing papers by Laura O’Regan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Laura O’Regan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Laura O’Regan. The network helps show where Laura O’Regan may publish in the future.

Co-authorship network of co-authors of Laura O’Regan

This figure shows the co-authorship network connecting the top 25 collaborators of Laura O’Regan. A scholar is included among the top collaborators of Laura O’Regan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Laura O’Regan. Laura O’Regan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Microtubule Association of EML4–ALK V3 Is Key for the Elongated Cell Morphology and Enhanced Migration Observed in V3 Cells 2024 ·Cells ·(unknown), (unknown), Laura O’Regan, Kees R. Straatman, Andrew M. Fry	1
2	The mesenchymal morphology of cells expressing the EML4–ALK V3 oncogene is dependent on phosphorylation of Eg5 by NEK7 2024 ·Journal of Biological Chemistry ·(unknown), (unknown), Laura O’Regan, Giancarlo Barone, Susan W. Robinson, (unknown), Kees R. Straatman, Joan Roig, Andrew M. Fry	3
3	EML4-ALK Variant 3 Promotes Mitotic Errors and Spindle Assembly Checkpoint Deficiency Leading to Increased Microtubule Poison Sensitivity 2022 ·Molecular Cancer Research ·(unknown), Laura O’Regan, Jene Choi, Josephina Sampson, (unknown), Richard Bayliss, Sam Khan, Andrew M. Fry	11
4	Construction of a human hTERT RPE-1 cell line with inducible Cre for editing of endogenous genes 2022 ·Biology Open ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Laura O’Regan, Masato T. Kanemaki, Andrew M. Fry, Kouji Hirota, Kayoko Tanaka	4
5	Alternative Treatment Options to ALK Inhibitor Monotherapy for EML4-ALK-Driven Lung Cancer 2022 ·Cancers ·(unknown), (unknown), Laura O’Regan, Sam Khan, Richard Bayliss, Andrew M. Fry	9
6	BRCA1/MAD2L1 Deficiency Disrupts the Spindle Assembly Checkpoint to Confer Vinorelbine Resistance in Mesothelioma 2020 ·Molecular Cancer Therapeutics ·Sara Busacca, Laura O’Regan, (unknown), Annabel Sharkey, Alan G. Dawson, (unknown), (unknown), (unknown), (unknown), Naomi Guppy, Apostolos Nakas, Michael Sheaff, Aaron S. Mansfield, Sam M. Janes, Paul Baas, Andrew M. Fry, Dean A. Fennell	13
7	Mitotic phosphorylation by NEK6 and NEK7 reduces the microtubule affinity of EML4 to promote chromosome congression 2019 ·Science Signaling ·(unknown), Jessica M. Montgomery, Joseph Atherton, Laura O’Regan, Mark W. Richards, Kees R. Straatman, Daniel Röth, Anne Straube, Richard Bayliss, Carolyn A. Moores, Andrew M. Fry	34
8	Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate release 2018 ·Science Signaling ·(unknown), Sarah Sabir, Laura O’Regan, Josephina Sampson, Mark W. Richards, Nicolas Huguenin‐Dezot, James R. Ault, Jason W. Chin, Anastasia Zhuravleva, Andrew M. Fry, Richard Bayliss	11
9	Hsp72 and Nek6 Cooperate to Cluster Amplified Centrosomes in Cancer Cells 2017 ·Cancer Research ·Josephina Sampson, Laura O’Regan, Martin J.S. Dyer, Richard Bayliss, Andrew M. Fry	22
10	EML proteins in microtubule regulation and human disease 2016 ·Biochemical Society Transactions ·Andrew M. Fry, Laura O’Regan, Jessica M. Montgomery, (unknown), Richard Bayliss	25
11	Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression 2015 ·The Journal of Cell Biology ·Laura O’Regan, Josephina Sampson, Mark W. Richards, Axel Knebel, Daniel Röth, Fiona E. Hood, Anne Straube, Stephen Royle, Richard Bayliss, Andrew M. Fry	40
12	Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization 2015 ·Nature Communications ·(unknown), Mark W. Richards, Selena G. Burgess, Pablo Gallego, Sharon Yeoh, Laura O’Regan, David Reverter, Joan Roig, Andrew M. Fry, Richard Bayliss	45
13	Novel insights into the mechanisms of mitotic spindle assembly by NEK kinases 2015 ·Molecular & Cellular Oncology ·Suzanna L. Prosser, Laura O’Regan, Andrew M. Fry	13
14	Microtubule association of EML proteins and the EML4-ALK variant 3 oncoprotein require an N-terminal trimerization domain 2015 ·Biochemical Journal ·Mark W. Richards, Laura O’Regan, Daniel Röth, Jessica M. Montgomery, Anne Straube, Andrew M. Fry, Richard Bayliss	69
15	Histone deacetylase (HDAC) 1 and 2 are essential for accurate cell division and the pluripotency of embryonic stem cells 2014 ·Proceedings of the National Academy of Sciences ·(unknown), Richard D. Kelly, Laura O’Regan, Oliver M. Dovey, (unknown), Christopher J. Millard, (unknown), Andrew M. Fry, John W. R. Schwabe, Shaun M. Cowley	122
16	Crystal structure of EML1 reveals the basis for Hsp90 dependence of oncogenic EML4-ALK by disruption of an atypical β-propeller domain 2014 ·Proceedings of the National Academy of Sciences ·Mark W. Richards, (unknown), (unknown), Sara Busacca, Laura O’Regan, Andrew M. Fry, Dean A. Fennell, Richard Bayliss	75
17	Cell cycle regulation by the NEK family of protein kinases 2012 ·Journal of Cell Science ·Andrew M. Fry, Laura O’Regan, Sarah Sabir, Richard Bayliss	300
18	An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9 2009 ·Molecular Cell ·Mark W. Richards, Laura O’Regan, Corine Mas-Droux, Joëlle Blot, (unknown), Swen Hoelder, Andrew M. Fry, Richard Bayliss	78
19	The Nek6 and Nek7 Protein Kinases Are Required for Robust Mitotic Spindle Formation and Cytokinesis 2009 ·Molecular and Cellular Biology ·Laura O’Regan, Andrew M. Fry	134
20	Mitotic regulation by NIMA-related kinases 2007 ·Cell Division ·Laura O’Regan, Joëlle Blot, Andrew M. Fry	169

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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