Larry W. Hertel

4.7k total citations · 2 hit papers
32 papers, 3.9k citations indexed

About

Larry W. Hertel is a scholar working on Molecular Biology, Infectious Diseases and Organic Chemistry. According to data from OpenAlex, Larry W. Hertel has authored 32 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Molecular Biology, 9 papers in Infectious Diseases and 8 papers in Organic Chemistry. Recurrent topics in Larry W. Hertel's work include HIV/AIDS drug development and treatment (9 papers), DNA Repair Mechanisms (7 papers) and Biochemical and Molecular Research (7 papers). Larry W. Hertel is often cited by papers focused on HIV/AIDS drug development and treatment (9 papers), DNA Repair Mechanisms (7 papers) and Biochemical and Molecular Research (7 papers). Larry W. Hertel collaborates with scholars based in United States and Netherlands. Larry W. Hertel's co-authors include Gerald B. Grindey, William Plunkett, Sherri Chubb, Volker Heinemann, Julian S. Kroin, Peng Huang, Donna S. Shewach, G B Boder, Tina M. Hahn and Theodore S. Lawrence and has published in prestigious journals such as Journal of the American Chemical Society, Nucleic Acids Research and International Journal of Radiation Oncology*Biology*Physics.

In The Last Decade

Larry W. Hertel

32 papers receiving 3.8k citations

Hit Papers

Action of 2',2'-difluorodeoxycytidine on DNA synthesis. 1990 2026 2002 2014 1991 1990 250 500 750
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Action of 2',2'-difluorodeoxycytidine on DNA synthesis.
    1991 754 citations Sherri Chubb, Larry W. Hertel et al. PubMed profile →
  2. Evaluation of the antitumor activity of gemcitabine (2',2'-difluoro-2'-deoxycytidine).
    1990 601 citations Larry W. Hertel, G B Boder et al. PubMed profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Larry W. Hertel United States 22 2.0k 1.8k 696 625 462 32 3.9k
Gerald B. Grindey United States 29 2.1k 1.0× 2.7k 1.5× 1.0k 1.5× 714 1.1× 596 1.3× 84 5.4k
Donna S. Shewach United States 38 1.8k 0.9× 2.8k 1.6× 843 1.2× 690 1.1× 182 0.4× 98 5.0k
A H Calvert United Kingdom 34 2.0k 1.0× 1.9k 1.0× 719 1.0× 443 0.7× 448 1.0× 89 3.7k
Ann L. Jackman United Kingdom 34 1.5k 0.7× 1.9k 1.0× 413 0.6× 277 0.4× 757 1.6× 97 3.4k
Sherri Chubb United States 16 1.2k 0.6× 1.4k 0.8× 323 0.5× 319 0.5× 120 0.3× 21 2.6k
G. Peter Beardsley United States 31 749 0.4× 2.3k 1.3× 554 0.8× 275 0.4× 330 0.7× 69 4.0k
Christopher P. Leamon United States 43 1.7k 0.9× 3.2k 1.8× 560 0.8× 364 0.6× 921 2.0× 94 6.6k
H. M. Pinedo Netherlands 34 1.9k 0.9× 1.4k 0.8× 361 0.5× 199 0.3× 182 0.4× 101 3.4k
Charles W. Taylor United States 34 1.4k 0.7× 2.4k 1.4× 355 0.5× 430 0.7× 209 0.5× 82 4.3k
Stanley B. Kaye United Kingdom 35 2.5k 1.3× 3.2k 1.8× 627 0.9× 949 1.5× 113 0.2× 102 6.1k

Countries citing papers authored by Larry W. Hertel

Since Specialization
Citations

This map shows the geographic impact of Larry W. Hertel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larry W. Hertel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larry W. Hertel more than expected).

Fields of papers citing papers by Larry W. Hertel

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larry W. Hertel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larry W. Hertel. The network helps show where Larry W. Hertel may publish in the future.

Co-authorship network of co-authors of Larry W. Hertel

This figure shows the co-authorship network connecting the top 25 collaborators of Larry W. Hertel. A scholar is included among the top collaborators of Larry W. Hertel based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Larry W. Hertel. Larry W. Hertel is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Takeuchi, Kumiko, Todd J. Kohn, Vincent P. Rocco, et al.. (2003). Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3. Bioorganic & Medicinal Chemistry Letters. 13(22). 3939–3942. 18 indexed citations
2.
Takeuchi, Kumiko, Todd J. Kohn, Vincent P. Rocco, et al.. (2003). Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 2. Bioorganic & Medicinal Chemistry Letters. 13(14). 2393–2397. 20 indexed citations
3.
4.
Lawrence, Theodore S., Emily Yun‐Chia Chang, Tina M. Hahn, Larry W. Hertel, & Donna S. Shewach. (1996). Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine. International Journal of Radiation Oncology*Biology*Physics. 34(4). 867–872. 255 indexed citations
5.
Hausheer, Frederick H., Noel D. Jones, P. Seetharamulu, et al.. (1996). Ab initio quantum mechanical and X-ray crystallographic studies of gemcitabine and 2′-deoxy cytosine. Computers & Chemistry. 20(4). 459–467. 7 indexed citations
6.
Merriman, Ronald L., Larry W. Hertel, Richard M. Schultz, et al.. (1996). Comparison of the antitumor activity of gemcitabine and ara-C in a panel of human breast, colon, lung and pancreatic xenograft models. Investigational New Drugs. 14(3). 243–247. 71 indexed citations
7.
Gandhi, Varsha, et al.. (1996). Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA.. PubMed. 56(19). 4453–9. 60 indexed citations
8.
Gandhi, Varsha, Shin Mineishi, Ping Huang, et al.. (1995). Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells.. PubMed. 55(7). 1517–24. 31 indexed citations
9.
Schultz, Richard M., Ronald L. Merriman, John E. Toth, et al.. (1993). Evaluation of new anticancer agents against the MIA PaCa-2 and PANC-1 human pancreatic carcinoma xenografts.. PubMed. 5(6-7). 223–8. 57 indexed citations
10.
Shewach, Donna S., Kara Reynolds, & Larry W. Hertel. (1992). Nucleotide specificity of human deoxycytidine kinase.. Molecular Pharmacology. 42(3). 518–524. 99 indexed citations
11.
Richardson, Frank C., Katherine K. Richardson, Julian S. Kroin, & Larry W. Hertel. (1992). Synthesis and restriction enzyme analysis of oligodeoxyribonucleotides containing the anti-cancer drug 2', 2'-difluoro-2'-deoxycytidine. Nucleic Acids Research. 20(7). 1763–1768. 16 indexed citations
12.
Heinemann, Volker, Sherri Chubb, Arindam Sen, et al.. (1992). Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation.. PubMed. 52(3). 533–9. 276 indexed citations
13.
Grindey, Gerald B., Larry W. Hertel, & William Plunkett. (1990). Cytotoxicity and Antitumor Activity of 2′,2′-Difluorodeoxycytidine (Gemcitabine). Cancer Investigation. 8(2). 313–314. 29 indexed citations
14.
Heinemann, Volker, Sherri Chubb, A. Sen, et al.. (1990). Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine.. Molecular Pharmacology. 38(4). 567–572. 342 indexed citations
15.
Heinemann, Volker, Larry W. Hertel, Gerald B. Grindey, & William Plunkett. (1988). Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine.. PubMed. 48(14). 4024–31. 432 indexed citations
16.
Hertel, Larry W., Julian S. Kroin, Jerry W. Misner, & J. M. Tustin. (1988). Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2'-difluoro-D-ribofuranosyl nucleosides. The Journal of Organic Chemistry. 53(11). 2406–2409. 316 indexed citations
17.
18.
Paquette, Leo A., Larry W. Hertel, Rolf Gleiter, et al.. (1981). Electronic control of stereoselectivity. 8. The stereochemical course of electrophilic additions to aryl-substituted 9-isopropylidenebenzonorbornenes. Journal of the American Chemical Society. 103(24). 7106–7121. 41 indexed citations
19.
Paquette, Leo A., Larry W. Hertel, Rolf Gleiter, & M. C. BOEHM. (1978). Electronic control of stereoselectivity. 1. Singlet oxygen and related electrophilic additions to aryl-substituted 7-isopropylidenebenzonorbornenes. Journal of the American Chemical Society. 100(20). 6510–6512. 32 indexed citations
20.
Delia, Thomas J., et al.. (1977). Characterization of the aglycones of the toxic principle of the sea cucumber Holothuria atra. Toxicon. 15(5). 461–462. 6 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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