Larry W. Hertel

4.7k citations

32 papers · 3.9k indexed · 2 hit papers · h-index 22

Oncology top 1%
Cancer Research top 5%
Genetics top 2%
- Chronic Lymphocytic Leukemia Research 4
Pharmaceutical Science top 2%
Molecular Biology top 5%
- DNA Repair Mechanisms 7
- Biochemical and Molecular Research 7
- DNA and Nucleic Acid Chemistry 5
- Cancer therapeutics and mechanisms 4
Infectious Diseases
- HIV/AIDS drug development and treatment 9
Organic Chemistry
- Asymmetric Synthesis and Catalysis 4
Immunology
- Immunodeficiency and Autoimmune Disorders 3

Co-authors: Gerald B. Grindey William Plunkett Sherri Chubb Volker Heinemann Julian S. Kroin Peng Huang Donna S. Shewach G B Boder
Cited by: Oncology Cancer Research Genetics
Journals: Journal of the American Chemical Society (3 papers)Nucleic Acids Research (1 paper)International Journal of Radiation Oncology*Biology*Physics (1 paper)
Partner nations: United States Netherlands

In The Last Decade

Larry W. Hertel

32 papers receiving 3.8k citations

Hit Papers

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Peers

Countries citing papers authored by Larry W. Hertel

Since Specialization

Citations

This map shows the geographic impact of Larry W. Hertel's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Larry W. Hertel with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Larry W. Hertel more than expected).

Fields of papers citing papers by Larry W. Hertel

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Larry W. Hertel. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Larry W. Hertel. The network helps show where Larry W. Hertel may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Larry W. Hertel, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Larry W. Hertel Line = papers co-authored together Larry W. Hertel links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Advances toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 3 Bioorganic & Medicinal Chemistry Letters ·Kumiko Takeuchi,Todd J. Kohn,Nicholas A Honigschmidt,Vincent P. Rocco,Patrick Spinazze,Steven T Atkinson,Larry W. Hertel,David L. Nelson,David B. Wainscott,Laura Ahmad,Janice Shaw,Penny G. Threlkeld,David T. Wong	2003	18
2	Advances Toward new antidepressants beyond SSRIs: 1-aryloxy-3-piperidinylpropan-2-ols with dual 5-HT1A receptor antagonism/SSRI activities. Part 2 Bioorganic & Medicinal Chemistry Letters ·Kumiko Takeuchi,Todd J. Kohn,Nicholas A Honigschmidt,Vincent P. Rocco,Patrick Spinazze,Daniel J. Koch,Steven T Atkinson,Larry W. Hertel,David L. Nelson,David B. Wainscott,Laura Ahmad,Janice Shaw,Penny G. Threlkeld,David T. Wong	2003	20
3	Comparison of the Mechanism of Cytotoxicity of 2-Chloro-9-(2-deoxy-2-fluoro-β-d-arabinofuranosyl)adenine, 2-Chloro-9-(2-deoxy-2-fluoro-β-d-ribofuranosyl)adenine, and 2-Chloro-9-(2-deoxy-2,2-difluoro-β-d-ribofuranosyl)adenine in CEM Cells Molecular Pharmacology ·William B. Parker,Sue C. Shaddix,Lucy M. Rose,Donna S. Shewach,Larry W. Hertel,John A. Secrist,John A. Montgomery,L. Lee Bennett	1999	35
4	Radiosensitization of pancreatic cancer cells by 2′,2′-difluoro-2′-deoxycytidine International Journal of Radiation OncologyBiologyPhysics ·Theodore S. Lawrence,Emily Yun‐Chia Chang,Tina M. Hahn,Larry W. Hertel,Donna S. Shewach	1996	255
5	Ab initio quantum mechanical and X-ray crystallographic studies of gemcitabine and 2′-deoxy cytosine Computers & Chemistry ·Frederick H. Hausheer,Noel D. Jones,P. Seetharamulu,U. Chandra Singh,Jack B. Deeter,Larry W. Hertel,Julian S. Kroin	1996	7
6	Comparison of the antitumor activity of gemcitabine and ara-C in a panel of human breast, colon, lung and pancreatic xenograft models Investigational New Drugs ·Ronald L. Merriman,Larry W. Hertel,Richard M. Schultz,Peter J. Houghton,Janet A. Houghton,Pamela Rutherford,Lee R. Tanzer,G B Boder,Gerald B. Grindey	1996	71
7	Excision of 2',2'-difluorodeoxycytidine (gemcitabine) monophosphate residues from DNA. PubMed ·Varsha Gandhi,Jaswinder Legha,Feng Chen,Larry W. Hertel,William Plunkett	1996	60
8	Cytotoxicity, metabolism, and mechanisms of action of 2',2'-difluorodeoxyguanosine in Chinese hamster ovary cells. PubMed ·Varsha Gandhi,Shin Mineishi,Ping Huang,A J Chapman,Yang Yu,F. Chen,Billie Nowak,Sherri Chubb,Larry W. Hertel,William Plunkett	1995	31
9	Evaluation of new anticancer agents against the MIA PaCa-2 and PANC-1 human pancreatic carcinoma xenografts. PubMed ·Richard M. Schultz,Ronald L. Merriman,John E. Toth,Johannes Zimmermann,Larry W. Hertel,Sherri L. Andis,Danette Dudley,Pamela Rutherford,Lee R. Tanzer,Gerald B. Grindey	1993	57
10	Nucleotide specificity of human deoxycytidine kinase. Molecular Pharmacology ·Donna S. Shewach,Kara Reynolds,Larry W. Hertel	1992	99
11	Synthesis and restriction enzyme analysis of oligodeoxyribonucleotides containing the anti-cancer drug 2', 2'-difluoro-2'-deoxycytidine Nucleic Acids Research ·Frank C. Richardson,Katherine K. Richardson,Julian S. Kroin,Larry W. Hertel	1992	16
12	Cellular elimination of 2',2'-difluorodeoxycytidine 5'-triphosphate: a mechanism of self-potentiation. PubMed ·Volker Heinemann,Yi-Zheng Xu,Sherri Chubb,Arindam Sen,Larry W. Hertel,Gerald B. Grindey,William Plunkett	1992	276
13	Cytotoxicity and Antitumor Activity of 2′,2′-Difluorodeoxycytidine (Gemcitabine) Cancer Investigation ·Gerald B. Grindey,Larry W. Hertel,William Plunkett	1990	29
14	Inhibition of ribonucleotide reduction in CCRF-CEM cells by 2',2'-difluorodeoxycytidine. Molecular Pharmacology ·Volker Heinemann,Yi-Zheng Xu,Sherri Chubb,A. Sen,Larry W. Hertel,Gerald B. Grindey,William Plunkett	1990	342
15	Comparison of the cellular pharmacokinetics and toxicity of 2',2'-difluorodeoxycytidine and 1-beta-D-arabinofuranosylcytosine. PubMed ·Volker Heinemann,Larry W. Hertel,Gerald B. Grindey,William Plunkett	1988	432
16	Synthesis of 2-deoxy-2,2-difluoro-D-ribose and 2-deoxy-2,2'-difluoro-D-ribofuranosyl nucleosides The Journal of Organic Chemistry ·Larry W. Hertel,Julian S. Kroin,Jerry W. Misner,J. M. Tustin	1988	316
17	Electronic control of stereoselectivity. 10. Aryl substituent effects on electrophilic stereoselection in 11-isopropylidenedibenzonorbornadienes. Direct competition of dissimilarly functionalized benzo groups The Journal of Organic Chemistry ·Leo A. Paquette,Franćois Klinger,Larry W. Hertel	1981	7
18	Electronic control of stereoselectivity. 8. The stereochemical course of electrophilic additions to aryl-substituted 9-isopropylidenebenzonorbornenes Journal of the American Chemical Society ·Leo A. Paquette,Larry W. Hertel,Rolf Gleiter,M. C. BOEHM,Mark A. Beno,Gary G. Christoph	1981	41
19	Electronic control of stereoselectivity. 1. Singlet oxygen and related electrophilic additions to aryl-substituted 7-isopropylidenebenzonorbornenes Journal of the American Chemical Society ·Leo A. Paquette,Larry W. Hertel,Rolf Gleiter,M. C. BOEHM	1978	32
20	Characterization of the aglycones of the toxic principle of the sea cucumber Holothuria atra Toxicon ·Thomas J. Delia,Larry W. Hertel,Larry W. Wittle	1977	6

About Larry W. Hertel

Larry W. Hertel is a scholar working on Infectious Diseases, Genetics and Molecular Biology, having authored 32 papers that have together received 3.9k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (9 papers), DNA Repair Mechanisms (7 papers), Biochemical and Molecular Research (7 papers), DNA and Nucleic Acid Chemistry (5 papers), Chronic Lymphocytic Leukemia Research (4 papers), Cancer therapeutics and mechanisms (4 papers), Asymmetric Synthesis and Catalysis (4 papers) and Immunodeficiency and Autoimmune Disorders (3 papers). The work is most often cited by research in Oncology (2.0k citations), Cancer Research (625 citations) and Genetics (366 citations). Larry W. Hertel has collaborated with scholars based in United States and Netherlands. Frequent co-authors include Gerald B. Grindey, William Plunkett, Sherri Chubb, Volker Heinemann, Julian S. Kroin, Peng Huang, Donna S. Shewach, G B Boder, Tina M. Hahn and Theodore S. Lawrence. Their work appears in journals such as Journal of the American Chemical Society, Nucleic Acids Research and International Journal of Radiation Oncology*Biology*Physics.

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