Yehuda G. Assaraf

21.3k total citations · 8 hit papers
262 papers, 17.0k citations indexed

About

Yehuda G. Assaraf is a scholar working on Molecular Biology, Oncology and Rheumatology. According to data from OpenAlex, Yehuda G. Assaraf has authored 262 papers receiving a total of 17.0k indexed citations (citations by other indexed papers that have themselves been cited), including 149 papers in Molecular Biology, 91 papers in Oncology and 46 papers in Rheumatology. Recurrent topics in Yehuda G. Assaraf's work include Drug Transport and Resistance Mechanisms (64 papers), Folate and B Vitamins Research (39 papers) and Acute Lymphoblastic Leukemia research (34 papers). Yehuda G. Assaraf is often cited by papers focused on Drug Transport and Resistance Mechanisms (64 papers), Folate and B Vitamins Research (39 papers) and Acute Lymphoblastic Leukemia research (34 papers). Yehuda G. Assaraf collaborates with scholars based in Israel, Netherlands and United States. Yehuda G. Assaraf's co-authors include Yoav D. Livney, Gerrit Jansen, Benny Zhitomirsky, Zhe‐Sheng Chen, Gera D. Eytan, Nitzan Gonen, Michal Stark, Alina Shapira, Godefridus J. Peters and Ilan Ifergan and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Blood.

In The Last Decade

Yehuda G. Assaraf

255 papers receiving 16.8k citations

Hit Papers

Overcoming ABC transporter-mediated multidrug resistance:... 2012 2026 2016 2021 2016 2018 2019 2015 2012 100 200 300 400 500
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Overcoming ABC transporter-mediated multidrug resistance: Molecular mechanisms and novel therapeutic drug strategies
    2016 555 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  2. Modulating ROS to overcome multidrug resistance in cancer
    2018 545 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  3. The multi-factorial nature of clinical multidrug resistance in cancer
    2019 409 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  4. Lysosomes as mediators of drug resistance in cancer
    2015 380 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  5. Antifolates in cancer therapy: Structure, activity and mechanisms of drug resistance
    2012 356 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  6. The folate receptor as a rational therapeutic target for personalized cancer treatment
    2014 329 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  7. Taxanes in cancer treatment: Activity, chemoresistance and its overcoming
    2021 221 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →
  8. Multidrug resistance proteins (MRPs): Structure, function and the overcoming of cancer multidrug resistance
    2021 171 citations Yehuda G. Assaraf et al. Drug Resistance Updates profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yehuda G. Assaraf Israel 70 9.4k 5.7k 2.5k 1.9k 1.7k 262 17.0k
Ting‐Chao Chou United States 60 14.1k 1.5× 8.1k 1.4× 2.2k 0.9× 1.3k 0.7× 1.2k 0.7× 350 29.3k
Herbert M. Pinedo Netherlands 91 12.1k 1.3× 15.8k 2.8× 3.5k 1.4× 962 0.5× 928 0.5× 571 29.8k
Charles Dumontet France 69 9.2k 1.0× 8.6k 1.5× 1.9k 0.8× 475 0.3× 627 0.4× 377 20.7k
Maurizio D’Incalci Italy 69 8.4k 0.9× 6.5k 1.1× 3.2k 1.3× 465 0.2× 463 0.3× 531 17.4k
Suresh V. Ambudkar United States 79 11.1k 1.2× 14.4k 2.5× 1.4k 0.5× 1.1k 0.6× 877 0.5× 315 23.8k
Merrill J. Egorin United States 66 5.9k 0.6× 5.5k 1.0× 1.0k 0.4× 622 0.3× 529 0.3× 380 14.2k
Gabriel Lopez‐Berestein United States 78 13.2k 1.4× 3.8k 0.7× 6.1k 2.4× 1.4k 0.8× 1.1k 0.6× 349 21.1k
Tito Fojo United States 72 11.7k 1.2× 13.2k 2.3× 4.7k 1.9× 1.4k 0.7× 1.2k 0.7× 265 24.3k
Chris Reutelingsperger Netherlands 60 9.4k 1.0× 1.3k 0.2× 1.4k 0.6× 642 0.3× 1.1k 0.7× 260 18.4k
Takashi Tsuruo Japan 89 16.6k 1.8× 12.4k 2.2× 2.8k 1.1× 652 0.3× 476 0.3× 446 27.7k

Countries citing papers authored by Yehuda G. Assaraf

Since Specialization
Citations

This map shows the geographic impact of Yehuda G. Assaraf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yehuda G. Assaraf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yehuda G. Assaraf more than expected).

Fields of papers citing papers by Yehuda G. Assaraf

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yehuda G. Assaraf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yehuda G. Assaraf. The network helps show where Yehuda G. Assaraf may publish in the future.

Co-authorship network of co-authors of Yehuda G. Assaraf

This figure shows the co-authorship network connecting the top 25 collaborators of Yehuda G. Assaraf. A scholar is included among the top collaborators of Yehuda G. Assaraf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yehuda G. Assaraf. Yehuda G. Assaraf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Ding, Ming, Yanyan Lin, Yao Chen, et al.. (2025). Therapeutic targeting de novo purine biosynthesis driven by β-catenin-dependent PPAT upregulation in hepatoblastoma. Cell Death and Disease. 16(1). 179–179. 3 indexed citations
2.
Cao, Bihui, Manting Liu, Zecong Xiao, et al.. (2025). CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors. Cell Reports Medicine. 6(2). 101965–101965. 1 indexed citations
3.
Wang, Qingshui, You‐Yu Lin, Yu Yan, et al.. (2025). Modulation of DAPK1 expression by its alternative splice variant DAPK1-215 in cancer. Journal of Translational Medicine. 23(1). 85–85.
4.
Chen, Yao, Yiming Lu, Zhiyi Zhou, et al.. (2025). Targeted deprivation of STAT6 sensitizes acute lymphoblastic leukemia cells to cytarabine in vivo and in vitro: clinical implications. Cell Death and Disease. 16(1). 669–669.
5.
Tamari, Tal, et al.. (2024). Inhibition of osteosarcoma metastasis in vivo by targeted downregulation of MMP1 and MMP9. Matrix Biology. 134. 48–58. 5 indexed citations
6.
Hashimshony, Tamar, Andreas C. Fröbius, Nitsan Dahan, et al.. (2024). A transcriptomic examination of encased rotifer embryos reveals the developmental trajectory leading to long-term dormancy; are they “animal seeds”?. BMC Genomics. 25(1). 119–119. 3 indexed citations
7.
Jonge, Róbert de, Eduard A. Struys, Cees B.M. Oudejans, et al.. (2023). Methotrexate Provokes Disparate Folate Metabolism Gene Expression and Alternative Splicing in Ex Vivo Monocytes and GM-CSF- and M-CSF-Polarized Macrophages. International Journal of Molecular Sciences. 24(11). 9641–9641. 4 indexed citations
8.
Stark, Michal, Shachar Raz, & Yehuda G. Assaraf. (2021). Folylpoly-ɣ-glutamate synthetase association to the cytoskeleton: Implications to folate metabolon compartmentalization. Journal of Proteomics. 239. 104169–104169. 7 indexed citations
9.
Golan, Yarden, Raphael Alhadeff, Arieh Warshel, & Yehuda G. Assaraf. (2019). ZnT2 is an electroneutral proton-coupled vesicular antiporter displaying an apparent stoichiometry of two protons per zinc ion. PLoS Computational Biology. 15(3). e1006882–e1006882. 30 indexed citations
10.
Giovannetti, Elisa, Paolo Andrea Zucali, Yehuda G. Assaraf, et al.. (2017). Role of proton-coupled folate transporter in pemetrexed resistance of mesothelioma: clinical evidence and new pharmacological tools. Annals of Oncology. 28(11). 2725–2732. 37 indexed citations
11.
Wijdeven, Ruud H., Baoxu Pang, Yehuda G. Assaraf, & Jacques Neefjes. (2016). Old drugs, novel ways out: Drug resistance toward cytotoxic chemotherapeutics. Drug Resistance Updates. 28. 65–81. 162 indexed citations
12.
Peters, Godefridus J., Elena Galvani, Gerrit Jansen, Yehuda G. Assaraf, & Elisa Giovannetti. (2013). Thymidylate synthase inhibitors for thoracic tumors. Pteridines. 24(1). 57–67. 1 indexed citations
13.
Gotink, Kristy J., Henk J. Broxterman, Mariëtte Labots, et al.. (2011). Lysosomal Sequestration of Sunitinib: A Novel Mechanism of Drug Resistance. Clinical Cancer Research. 17(23). 7337–7346. 290 indexed citations
14.
Heijden, Joost W van der, Ruud Oerlemans, Paul P. Tak, et al.. (2009). Involvement of breast cancer resistance protein expression on rheumatoid arthritis synovial tissue macrophages in resistance to methotrexate and leflunomide. Arthritis & Rheumatism. 60(3). 669–677. 54 indexed citations
15.
Beretta, Giovanni Luca, Valentina Benedetti, Giacomo Cossa, et al.. (2009). Increased levels and defective glycosylation of MRPs in ovarian carcinoma cells resistant to oxaliplatin. Biochemical Pharmacology. 79(8). 1108–1117. 90 indexed citations
16.
Oerlemans, Ruud, Ben A. C. Dijkmans, Gertjan J.L. Kaspers, et al.. (2006). Acquired resistance to chloroquine in human CEM T cells is mediated by multidrug resistance–associated protein 1 and provokes high levels of cross‐resistance to glucocorticoids. Arthritis & Rheumatism. 54(2). 557–568. 31 indexed citations
17.
18.
Assaraf, Yehuda G., et al.. (2004). Targeting an extracellular epitope of the human multidrug resistance protein 1 (MRP1) in malignant cells with a novel recombinant single chain Fv antibody. International Journal of Cancer. 110(6). 882–890. 11 indexed citations
19.
Peters, Godefridus J., David G. Priest, Yehuda G. Assaraf, et al.. (2002). Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis. Biochemical Pharmacology. 63(2). 105–115. 49 indexed citations
20.
Assaraf, Yehuda G., Uriel Bachrach, Jacob Golenser, & Dan T. Spira. (1983). The role of polyamines in human malaria parasites. Journal of Eukaryotic Microbiology. 30(3). 54. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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