Kenneth L. Kirk

9.4k total citations · 4 hit papers
183 papers, 7.8k citations indexed

About

Kenneth L. Kirk is a scholar working on Molecular Biology, Organic Chemistry and Pharmaceutical Science. According to data from OpenAlex, Kenneth L. Kirk has authored 183 papers receiving a total of 7.8k indexed citations (citations by other indexed papers that have themselves been cited), including 83 papers in Molecular Biology, 79 papers in Organic Chemistry and 62 papers in Pharmaceutical Science. Recurrent topics in Kenneth L. Kirk's work include Fluorine in Organic Chemistry (59 papers), Chemical Synthesis and Analysis (25 papers) and Synthesis and Reactions of Organic Compounds (22 papers). Kenneth L. Kirk is often cited by papers focused on Fluorine in Organic Chemistry (59 papers), Chemical Synthesis and Analysis (25 papers) and Synthesis and Reactions of Organic Compounds (22 papers). Kenneth L. Kirk collaborates with scholars based in United States, Japan and Germany. Kenneth L. Kirk's co-authors include Louis A. Cohen, Mark Levine, Michael Graham Espey, Andrew Y. Sun, Murali C. Krishna, Kenneth A. Jacobson, John W. Daly, Cyrus R. Creveling, William L. Padgett and Qi Chen and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Kenneth L. Kirk

181 papers receiving 7.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Fluorination in Medicinal Chemistry: Methods, Strategies, and Recent Developments

2008 1.0k citations Kenneth L. Kirk profile →
Fluorine in medicinal chemistry: Recent therapeutic applications of fluorinated small molecules

2006 797 citations Kenneth L. Kirk Journal of Fluorine Chemistry profile →
Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice

2008 676 citations Michael Graham Espey, Andrew Y. Sun et al. Proceedings of the National Academy of Sciences profile →
Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo

2007 554 citations Qi Chen, Michael Graham Espey et al. Proceedings of the National Academy of Sciences profile →

Peers

Kenneth L. Kirk

Richard B. Silverman United States

Christian Schöneich United States

Enrico Rizzarelli Italy

Tomi Järvinen Finland

Joshua Rokach United States

Carla Ghelardini Italy

Alan Davison United Kingdom

Roberto Pellicciari Italy

Alan P. Kozikowski United States

Anders Hallberg Sweden

Richard B. Silverman United States

Kenneth L. Kirk

3.7k ×1.1

613 ×0.3

5.1k ×2.3

268 ×0.2

847 ×1.0

Citations per year, relative to Kenneth L. Kirk Kenneth L. Kirk (= 1×) peers Richard B. Silverman

Countries citing papers authored by Kenneth L. Kirk

Since Specialization

Citations

This map shows the geographic impact of Kenneth L. Kirk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth L. Kirk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth L. Kirk more than expected).

Fields of papers citing papers by Kenneth L. Kirk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth L. Kirk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth L. Kirk. The network helps show where Kenneth L. Kirk may publish in the future.

Co-authorship network of co-authors of Kenneth L. Kirk

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth L. Kirk. A scholar is included among the top collaborators of Kenneth L. Kirk based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth L. Kirk. Kenneth L. Kirk is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ko, Hyojin, Arijit Das, Rhonda L. Carter, et al.. (2009). Molecular recognition in the P2Y14 receptor: Probing the structurally permissive terminal sugar moiety of uridine-5′-diphosphoglucose. Bioorganic & Medicinal Chemistry. 17(14). 5298–5311. 32 indexed citations

Fujiwara, Tomoya, et al.. (2008). Synthetic studies of 3-(3-fluorooxindol-3-yl)-l-alanine. Journal of Fluorine Chemistry. 129(9). 829–835. 12 indexed citations

Takéuchi, Yoshio, Tomoya Fujiwara, Hideki Miyataka, et al.. (2008). Possible involvement of radical intermediates in the inhibition of cysteine proteases by allenyl esters and amides. Bioorganic & Medicinal Chemistry Letters. 18(23). 6202–6205. 6 indexed citations

Heredia‐Moya, Jorge & Kenneth L. Kirk. (2008). An improved synthesis of arsenic–biotin conjugates. Bioorganic & Medicinal Chemistry. 16(10). 5743–5746. 21 indexed citations

Yoshida, Shin�ichi, et al.. (2008). Fluorinated phenylcyclopropylamines. Journal of Fluorine Chemistry. 129(9). 875–880. 15 indexed citations

Uto, Yoshihiro, Hideko Nagasawa, Chengzhe Jin, et al.. (2008). Design of antiangiogenic hypoxic cell radiosensitizers: 2-Nitroimidazoles containing a 2-aminomethylene-4-cyclopentene-1,3-dione moiety. Bioorganic & Medicinal Chemistry. 16(11). 6042–6053. 24 indexed citations

Chen, Qi, Michael Graham Espey, Andrew Y. Sun, et al.. (2007). Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo. Proceedings of the National Academy of Sciences. 104(21). 8749–8754. 554 indexed citations breakdown →

Zhang, Xinyan, Fan Yang, Joong‐Youn Shim, et al.. (2007). Identification of arsenic-binding proteins in human breast cancer cells. Cancer Letters. 255(1). 95–106. 79 indexed citations

Eichler, Jack F., et al.. (2005). Biosynthetic Incorporation of Fluorohistidine into Proteins in E. coli: A New Probe of Macromolecular Structure. ChemBioChem. 6(12). 2170–2173. 33 indexed citations

10.

Rosen, T.C., Shin�ichi Yoshida, Kenneth L. Kirk, & Günter Haufe. (2004). Fluorinated Phenylcyclopropylamines as Inhibitors of Monoamine Oxidases. ChemBioChem. 5(8). 1033–1043. 31 indexed citations

11.

Hayakawa, Yoshio, et al.. (2003). Convenient syntheses of biogenic aldehydes, 3,4-dihydroxyphenylacetaldehyde and 3,4-dihydroxyphenylglycolaldehyde. Bioorganic Chemistry. 31(2). 191–197. 13 indexed citations

12.

Hori, Hitoshi, Hideko Nagasawa, Yoshihiro Uto, et al.. (2002). TX-1123: an antitumor 2-hydroxyarylidene-4-cyclopentene-1,3-dione as a protein tyrosine kinase inhibitor having low mitochondrial toxicity. Bioorganic & Medicinal Chemistry. 10(10). 3257–3265. 53 indexed citations

13.

Lamensdorf, Itschak, et al.. (2000). 3,4-Dihydroxyphenylacetaldehyde potentiates the toxic effects of metabolic stress in PC12 cells. Brain Research. 868(2). 191–201. 94 indexed citations

14.

Goldstein, David S., Ehud Grossman, Peter C. Chang, et al.. (1991). Positron emission imaging of cardiac sympathetic innervation and function using 18F-6-fluorodopamine: effects of chemical sympathectomy by 6-hydroxydopamine. Journal of Hypertension. 9(5). 417–423. 35 indexed citations

15.

HEBEL, D., et al.. (1991). Direct electrophilic fluorination of tyrosine in dermorphin analogues and its effect on biological activity, receptor affinity and selectivity. International journal of peptide & protein research. 37(5). 430–439. 9 indexed citations

16.

Phillips, Robert S., et al.. (1990). Oxygenation of fluorinated tyrosines by mushroom tyrosinase releases fluoride ion. Archives of Biochemistry and Biophysics. 276(1). 65–69. 30 indexed citations

17.

Jacobson, Kenneth A., et al.. (1988). A prosthetic group for the rapid introduction of fluorine into peptides and functionalized drugs. Journal of Fluorine Chemistry. 39(3). 339–347. 19 indexed citations

18.

Eisenhofer, Graeme, et al.. (1988). Simultaneous determination of endogenous catechols and exogenous 2- and 6-fluorinated catechols in tissue and plasma using liquid chromatography with electrochemical detection. Journal of Chromatography B Biomedical Sciences and Applications. 431(1). 156–162. 7 indexed citations

19.

Adejare, Adeboye, Fabian Gusovsky, William L. Padgett, et al.. (1988). Syntheses and adrenergic activities of ring-fluorinated epinephrines. Journal of Medicinal Chemistry. 31(10). 1972–1977. 20 indexed citations

20.

Jacobson, Kenneth A., Lewis K. Pannell, Kenneth L. Kirk, Henry M. Fales, & Edward A. Sokoloski. (1986). Californium-252 plasma desorption mass spectrometry as an aid in the synthesis of a series of adenosine and xanthine conjugates. Journal of the Chemical Society Perkin Transactions 1. 1986. 2143–2143. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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