Ke Shuai

15.4k total citations · 7 hit papers
62 papers, 12.2k citations indexed

About

Ke Shuai is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, Ke Shuai has authored 62 papers receiving a total of 12.2k indexed citations (citations by other indexed papers that have themselves been cited), including 31 papers in Molecular Biology, 31 papers in Oncology and 29 papers in Immunology. Recurrent topics in Ke Shuai's work include Cytokine Signaling Pathways and Interactions (27 papers), interferon and immune responses (20 papers) and Ubiquitin and proteasome pathways (14 papers). Ke Shuai is often cited by papers focused on Cytokine Signaling Pathways and Interactions (27 papers), interferon and immune responses (20 papers) and Ubiquitin and proteasome pathways (14 papers). Ke Shuai collaborates with scholars based in United States, China and Poland. Ke Shuai's co-authors include Bin Liu, James Darnell, Chris Schindler, Vincent R. Prezioso, Jiayu Liao, Bin Liu, Chan D. Chung, George R. Stark, Johanna ten Hoeve and Sajjad A. Qureshi and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Ke Shuai

60 papers receiving 12.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Regulation of JAK–STAT signalling in the immune system

2003 1.1k citations Ke Shuai, Bin Liu profile →
Specific Inhibition of Stat3 Signal Transduction by PIAS3

1997 813 citations Bin Liu, Ke Shuai et al. profile →
Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor

1992 776 citations Chris Schindler, Ke Shuai et al. profile →
Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions

1994 709 citations Ke Shuai, Curt M. Horvath et al. Cell profile →
A Single Phosphotyrosine Residue of Stat91 Required for Gene Activation by Interferon-γ

1993 706 citations Ke Shuai, James Darnell et al. profile →
Activation of Transcription by IFN-γ: Tyrosine Phosphorylation of a 91-kD DNA Binding Protein

1992 693 citations Ke Shuai, Chris Schindler et al. profile →
Inhibition of Stat1-mediated gene activation by PIAS1

1998 627 citations Bin Liu, Ke Shuai et al. Proceedings of the National Academy of Sciences profile →

Peers

Countries citing papers authored by Ke Shuai

Since Specialization

Citations

This map shows the geographic impact of Ke Shuai's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ke Shuai with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ke Shuai more than expected).

Fields of papers citing papers by Ke Shuai

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ke Shuai. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ke Shuai. The network helps show where Ke Shuai may publish in the future.

Co-authorship network of co-authors of Ke Shuai

This figure shows the co-authorship network connecting the top 25 collaborators of Ke Shuai. A scholar is included among the top collaborators of Ke Shuai based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ke Shuai. Ke Shuai is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Trends in food protein-induced allergic proctocolitis (FPIAP): Mechanisms and treatment targeting gut microbiome 2025 ·Clinics and Research in Hepatology and Gastroenterology ·Yan Liu, (unknown), Lina Shen, Ke Shuai, Chao Zhang, Zhifeng Ning	0
2	Biosponge‐Armored Nanodots Restore Redox‐Calcium Homeostasis to Mitigate Reperfusion‐Induced Injury in Ischemic Stroke 2025 ·Advanced Functional Materials ·Xinyue Cao, Ke Shuai, Peng Wang, Jiacheng Xu, (unknown), Ying Wang, Xiaoyan Li, (unknown), Kai Chen, Yu Chen, (unknown), Liang Chen	0
3	Multi-Strategy Improved Red-Tailed Hawk Algorithm for Real-Environment Unmanned Aerial Vehicle Path Planning 2025 ·Biomimetics ·(unknown), (unknown), Pengfei Hu, (unknown), Ke Shuai, (unknown), Pai Zhang	2
4	Prognostic Analysis and Risk Factors Associated with Fetal Ventriculomegaly 2021 ·Pediatric Neurosurgery ·(unknown), Hongzhan Liao, Wenbo Wang, (unknown), (unknown), Ke Shuai, Jing Xiao, Qinghua Li, Xuewei Xia, Yong Li	3
5	Effects of soybean meal replacement by fermented soybean meal on growth performance and intestinal tissue structure of common carp (Cyprinus carpio). 2015 ·Dongwu yingyang xuebao ·(unknown), (unknown), Ke Shuai, Yuping Deng	3
6	PIAS1 Regulates Breast Tumorigenesis through Selective Epigenetic Gene Silencing 2014 ·PLoS ONE ·Bin Liu, (unknown), (unknown), (unknown), Yonghui Yang, (unknown), Cary Hsu, (unknown), Neil A. O’Brien, Yusheng Jin, Guoping Fan, Timothy F. Lane, Jianyu Rao, Dennis J. Slamon, Ke Shuai	33
7	Pillars article: Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor. Science. 1992. 257: 809-813. 2011 ·PubMed ·Chris Schindler, Ke Shuai, Vincent R. Prezioso, James Darnell	5
8	Pillars Article: Interferon-Dependent Tyrosine Phosphorylation of a Latent Cytoplasmic Transcription Factor. Science. 1992. 257: 809–813 2011 ·The Journal of Immunology ·Chris Schindler, Ke Shuai, Vincent R. Prezioso, James Darnell	1
9	Targeting the PIAS1 SUMO ligase pathway to control inflammation 2008 ·Trends in Pharmacological Sciences ·Bin Liu, Ke Shuai	54
10	Regulation of the sumoylation system in gene expression 2008 ·Current Opinion in Cell Biology ·Bin Liu, Ke Shuai	55
11	Proinflammatory Stimuli Induce IKKα-Mediated Phosphorylation of PIAS1 to Restrict Inflammation and Immunity 2007 ·Cell ·Bin Liu, Yonghui Yang, (unknown), Rachel R. Ogorzalek Loo, Hyunduk Jang, (unknown), (unknown), Sheldon Mink, David Shultz, Clifford J. Bellone, Joseph A. Loo, Ke Shuai	130
12	Implications of an antiparallel dimeric structure of nonphosphorylated STAT1 for the activation–inactivation cycle 2005 ·Proceedings of the National Academy of Sciences ·Minghao Zhong, Melissa A. Henriksen, Kenji Takeuchi, Olaf Schaefer, Bin Liu, Johanna ten Hoeve, Zhiyong Ren, Xiang Mao, Xiaohong Chen, Ke Shuai, James Darnell	126
13	PIAS1 selectively inhibits interferon-inducible genes and is important in innate immunity 2004 ·Nature Immunology ·Bin Liu, Sheldon Mink, Kelly A. Wong, Natalie Stein, (unknown), Paul W. Dempsey, Hong Wu, Ke Shuai	204
14	PIASx Is a Transcriptional Co-repressor of Signal Transducer and Activator of Transcription 4 2003 ·Journal of Biological Chemistry ·Taruna Arora, Bin Liu, (unknown), Jenny Kim, Theresa L. Murphy, Kenneth M. Murphy, Robert L. Modlin, Ke Shuai	93
15	Protein ISGylation modulates the JAK-STAT signaling pathway 2003 ·Genes & Development ·Oxana A. Malakhova, Ming Yan, Michael P. Malakhov, Youzhong Yuan, Kenneth J. Ritchie, Keun Il Kim, Luke F. Peterson, Ke Shuai, Dong‐Er Zhang	256
16	A Role for IL-12 Receptor Expression and Signal Transduction in Host Defense in Leprosy 2001 ·The Journal of Immunology ·Jenny Kim, Koichi Uyemura, Melissa K. Van Dyke, Annaliza J. Legaspi, Thomas H. Rea, Ke Shuai, Robert L. Modlin	38
17	The STAT family of proteins in cytokine signaling 1999 ·Progress in Biophysics and Molecular Biology ·Ke Shuai	70
18	The Suppressor of Cytokine Signaling (SOCS) 1 and SOCS3 but Not SOCS2 Proteins Inhibit Interferon-mediated Antiviral and Antiproliferative Activities 1998 ·Journal of Biological Chemistry ·(unknown), Ke Shuai	338
19	Interferon activation of the transcription factor Stat91 involves dimerization through SH2-phosphotyrosyl peptide interactions breakdown → 1994 ·Cell ·Ke Shuai, Curt M. Horvath, (unknown), Sajjad A. Qureshi, David Cowburn, James Darnell	709
20	Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins 1993 ·Nature ·Ke Shuai, Andrew Ziemiecki, Andrew F. Wilks, Ailsa G. Harpur, Henry B. Sadowski, Michael Gilman, James Darnell	429

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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