Karl J. Staples

5.0k citations

101 papers · 3.4k indexed · 1 hit paper · h-index 32

Immunology top 2%
Epidemiology top 2%
Pulmonary and Respiratory Medicine top 2%
Physiology top 5%
Molecular Biology

Co-authors: Tom Wilkinson Ben Nicholas Ratko Djukanović Kristoffer Ostridge Timothy Hinks Daniel C. Douek Rob Lambkin‐Williams Xiao-Ning Xu
Topics: Asthma and respiratory diseases (33 papers)Chronic Obstructive Pulmonary Disease (COPD) Research (27 papers)Immune Cell Function and Interaction (19 papers)
Cited by: Immunology Epidemiology Pulmonary and Respiratory Medicine
Journals: Proceedings of the National Academy of Sciences The Lancet Nature Medicine
Partner nations: United Kingdom United States Germany

In The Last Decade

Karl J. Staples

96 papers receiving 3.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

2012 766 citations Tom Wilkinson, Ben Nicholas et al. profile →

Peers

Countries citing papers authored by Karl J. Staples

Since Specialization

Citations

This map shows the geographic impact of Karl J. Staples's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karl J. Staples with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karl J. Staples more than expected).

Fields of papers citing papers by Karl J. Staples

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karl J. Staples. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karl J. Staples. The network helps show where Karl J. Staples may publish in the future.

Co-authorship network of co-authors of Karl J. Staples

This figure shows the co-authorship network connecting the top 25 collaborators of Karl J. Staples. A scholar is included among the top collaborators of Karl J. Staples based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karl J. Staples. Karl J. Staples is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Beyond Spirometry: Understanding COPD Origins to Support a New Diagnostic Approach 2025 ·ERJ Open Research ·(unknown),(unknown),(unknown),C. Mirella Spalluto,(unknown),Anna Freeman,Farhan Ullah,(unknown),(unknown),Alex Kong,Benjamin Welham,(unknown),Martha Purcell,(unknown),Karl J. Staples,Alastair Watson,Tom Wilkinson	0
2	A randomised controlled trial of EP395, a novel anti-inflammatory macrolide, in stable COPD patients 2025 ·ERJ Open Research ·Henrik Watz,Stephanie Korn,Oliver Kornmann,(unknown),Thomas S. Wilkinson,(unknown),Karl J. Staples,(unknown),Virginia Norris	0
3	Towards an artificial human lung: modelling organ-like complexity to aid mechanistic understanding 2022 ·European Respiratory Journal ·María Victoria Humbert,C. Mirella Spalluto,Joseph A. Bell,Cornelia Blume,Franco Conforti,Elizabeth R. Davies,(unknown),Paul Elkington,Hans Michael Haitchi,Claire Jackson,Mark G. Jones,Matthew Loxham,Jane S. Lucas,Hywel Morgan,Marta E. Polak,Karl J. Staples,Emily J. Swindle,Liku B. Tezera,Alastair Watson,Tom Wilkinson	7
4	Antiviral Responses of Tissue-resident CD49a+ Lung Natural Killer Cells Are Dysregulated in Chronic Obstructive Pulmonary Disease 2022 ·American Journal of Respiratory and Critical Care Medicine ·(unknown),Jemma Mayall,Chantal Donovan,Tatt Jhong Haw,Kurtis F. Budden,Nicole G. Hansbro,(unknown),Tania Maes,(unknown),Jay C. Horvat,Salim I. Khakoo,Tom Wilkinson,Philip M. Hansbro,Karl J. Staples	9
5	Unfractionated heparin inhibits live wild type SARS‐CoV‐2 cell infectivity at therapeutically relevant concentrations 2020 ·British Journal of Pharmacology ·Julia A. Tree,Jeremy E. Turnbull,Karen R. Buttigieg,Michael J. Elmore,Naomi S. Coombes,John Hogwood,Courtney J. Mycroft‐West,Marcelo A. Lima,Mark A. Skidmore,Richard Karlsson,Yen‐Hsi Chen,Zhang Yang,C. Mirella Spalluto,Karl J. Staples,Edwin A. Yates,Elaine Gray,Dave Singh,Tom Wilkinson,Clive Page,Miles W. Carroll	62
6	Human Lung Conventional Dendritic Cells Orchestrate Lymphoid Neogenesis during Chronic Obstructive Pulmonary Disease 2020 ·American Journal of Respiratory and Critical Care Medicine ·Thomas Naessens,Yannick Morias,(unknown),Ulf Gehrmann,(unknown),Johan Mattsson,Tina Baker,Gabriel Skogberg,Elisabeth Israelsson,Kristofer Thörn,Martijn J. Schuijs,B. Angermann,(unknown),Karl J. Staples,Danen Cunoosamy,Bart N. Lambrecht	43
7	Patient perceived barriers to exercise and their clinical associations in difficult asthma 2020 ·SHILAP Revista de lepidopterología ·Anna Freeman,David B. Hill,Colin Newell,Helen Moyses,Adnan Azim,Deborah A. Knight,Laura Presland,Matthew Harvey,Hans Michael Haitchi,Alastair Watson,Karl J. Staples,Ramesh Kurukulaaratchy,Tom Wilkinson	18
8	Dynamics of IFN-β Responses during Respiratory Viral Infection. Insights for Therapeutic Strategies 2019 ·American Journal of Respiratory and Critical Care Medicine ·Alastair Watson,(unknown),Christopher McCrae,Doriana Cellura,Hannah Burke,Danen Cunoosamy,Anna Freeman,Alex Hicks,Michael Hühn,Kristoffer Ostridge,Karl J. Staples,Outi Vaarala,Tom Wilkinson	55
9	Using Novel Computed Tomography Analysis to Describe the Contribution and Distribution of Emphysema and Small Airways Disease in Chronic Obstructive Pulmonary Disease 2019 ·Annals of the American Thoracic Society ·Kristoffer Ostridge,Kerry Gove,(unknown),Hannah Burke,Anna Freeman,Stephen Harden,Miranda Kirby,S. Peterson,Jered Sieren,(unknown),Outi Vaarala,Karl J. Staples,Tom Wilkinson	24
10	Impact of radiologically stratified exacerbations: insights into pneumonia aetiology in COPD 2018 ·Respiratory Research ·(unknown),Nicholas Williams,Kristoffer Ostridge,Jeanne‐Marie Devaster,Viktoriya Kim,Ngaire Coombs,Simon Bourne,Stuart C. Clarke,Stephen Harden,(unknown),Emmanuel Aris,Christophe Lambert,Andrew Tuck,Anthony P. Williams,Stephen A. Wootton,Karl J. Staples,Tom Wilkinson	24
11	IFN-γ Influences Epithelial Antiviral Responses via Histone Methylation of the RIG-I Promoter 2017 ·American Journal of Respiratory Cell and Molecular Biology ·C. Mirella Spalluto,Akul Singhania,Doriana Cellura,Christopher H. Woelk,Tilman Sánchez-Elsner,Karl J. Staples,Tom Wilkinson	19
12	Seasonality, risk factors and burden of community-acquired pneumonia in COPD patients: a population database study using linked health care records 2017 ·International Journal of COPD ·Nicholas Williams,Ngaire Coombs,Matthew Johnson,Lynn Josephs,(unknown),Karl J. Staples,Mike Thomas,Tom Wilkinson	62
13	Multitissue Transcriptomics Delineates the Diversity of Airway T Cell Functions in Asthma 2017 ·American Journal of Respiratory Cell and Molecular Biology ·Akul Singhania,(unknown),Caroline Smith,Daniel Horowitz,Karl J. Staples,Peter Howarth,Stephan D. Gadola,Ratko Djukanović,Christopher H. Woelk,Timothy Hinks	66
14	Human Lung Fibroblasts Present Bacterial Antigens to Autologous Lung Th Cells 2016 ·The Journal of Immunology ·Andrew J. Hutton,Marta E. Polak,C. Mirella Spalluto,(unknown),C. Pickard,Karl J. Staples,Jane A. Warner,Tom Wilkinson	21
15	Viral Inhibition of Bacterial Phagocytosis by Human Macrophages: Redundant Role of CD36 2016 ·PLoS ONE ·(unknown),(unknown),(unknown),(unknown),Ben Nicholas,(unknown),(unknown),(unknown),Anna S. Tocheva,Myron Christodoulides,Ratko Djukanović,Tom Wilkinson,Karl J. Staples	22
16	Steroid-induced Deficiency of Mucosal-associated Invariant T Cells in the Chronic Obstructive Pulmonary Disease Lung. Implications for Nontypeable Haemophilus influenzae Infection 2016 ·American Journal of Respiratory and Critical Care Medicine ·Timothy Hinks,(unknown),Anthony P. Williams,Ratko Djukanović,Karl J. Staples,Tom Wilkinson	79
17	Dysregulation of Antiviral Function of CD8+ T Cells in the Chronic Obstructive Pulmonary Disease Lung: Role of the PD-1–PD-L1 Axis 2015 ·American Journal of Respiratory and Critical Care Medicine ·Richard McKendry,(unknown),Hannah Burke,Ben Nicholas,Doriana Cellura,Aymen Al‐Shamkhani,Karl J. Staples,Tom Wilkinson	99
18	Comprehensive characterisation of T helper cells, cytotoxic T cells and novel invariant T cell phenotypes in human asthma 2013 ·European Respiratory Journal ·Timothy Hinks,Karl J. Staples,Salah Mansour,Caroline Smith,Jonathan Ward,Peter Howarth,Stephan D. Gadola,Ratko Djukanović	1
19	Chemokine Receptor 4 Plays a Key Role in T Cell Recruitment into the Airways of Asthmatic Patients 2010 ·The Journal of Immunology ·Pandurangan Vijayanand,(unknown),Guido Hartmann,Jaymin B. Morjaria,Grégory Seumois,Karl J. Staples,David A. Hall,(unknown),(unknown),Peter Howarth,Peter S. Friedmann,Ratko Djukanović	80
20	Adenosine 3′,5′-Cyclic Monophosphate (cAMP)-Dependent Inhibition of IL-5 from Human T Lymphocytes Is Not Mediated by the cAMP-Dependent Protein Kinase A 2001 ·The Journal of Immunology ·Karl J. Staples,Martin Bergmann,Katsuyuki Tomita,Miles D. Houslay,Ian McPhee,Peter J. Barnes,Mark A. Giembycz,Robert Newton	63

About Karl J. Staples

Karl J. Staples is a scholar working on Immunology, Physiology and Emergency Medical Services, having authored 101 papers that have together received 3.4k indexed citations. Recurring topics across this work include Asthma and respiratory diseases (33 papers), Chronic Obstructive Pulmonary Disease (COPD) Research (27 papers) and Immune Cell Function and Interaction (19 papers). The work is most often cited by research in Immunology (1.5k citations), Epidemiology (1.1k citations) and Pulmonary and Respiratory Medicine (914 citations). Karl J. Staples has collaborated with scholars based in United Kingdom, United States and Germany. Frequent co-authors include Tom Wilkinson, Ben Nicholas, Ratko Djukanović, Kristoffer Ostridge, Timothy Hinks, Daniel C. Douek, Rob Lambkin‐Williams, Xiao-Ning Xu, Andrew J. McMichael and Tao Dong. Their work appears in journals such as Proceedings of the National Academy of Sciences, The Lancet and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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