Karl Erik Hellström

15.0k total citations · 6 hit papers
172 papers, 11.8k citations indexed

About

Karl Erik Hellström is a scholar working on Immunology, Oncology and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Karl Erik Hellström has authored 172 papers receiving a total of 11.8k indexed citations (citations by other indexed papers that have themselves been cited), including 107 papers in Immunology, 64 papers in Oncology and 58 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Karl Erik Hellström's work include Immunotherapy and Immune Responses (73 papers), Monoclonal and Polyclonal Antibodies Research (54 papers) and Immune Cell Function and Interaction (41 papers). Karl Erik Hellström is often cited by papers focused on Immunotherapy and Immune Responses (73 papers), Monoclonal and Polyclonal Antibodies Research (54 papers) and Immune Cell Function and Interaction (41 papers). Karl Erik Hellström collaborates with scholars based in United States, Germany and South Africa. Karl Erik Hellström's co-authors include Ingegerd Hellström, Lieping Chen, Peter S. Linsley, Hans Sjögren, Jeffrey A. Ledbetter, George E. Pierce, Glenn A. Warner, Joseph P. Brown, George Klein and Hans Olof Sjögren and has published in prestigious journals such as Nature, New England Journal of Medicine and Cell.

In The Last Decade

Karl Erik Hellström

171 papers receiving 10.8k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Costimulation of antitumor immunity by the B7 counterreceptor for the T lymphocyte molecules CD28 and CTLA-4

1992 912 citations Lieping Chen, Karl Erik Hellström et al. profile →
Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 727 citations Ignacio Melero, Alejandro Aruffo et al. profile →
The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.

2003 582 citations Ingegerd Hellström, Martha Hayden-Ledbetter et al. PubMed profile →
Demonstration of resistance against methylcholanthrene-induced sarcomas in the primary autochthonous host.

1960 565 citations Karl Erik Hellström et al. PubMed profile →
Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens

1974 509 citations Karl Erik Hellström, Ingegerd Hellström Advances in immunology profile →
Cellular Immunity Against Tumor Antigens

1969 372 citations Karl Erik Hellström, Ingegerd Hellström profile →

Peers

Countries citing papers authored by Karl Erik Hellström

Since Specialization

Citations

This map shows the geographic impact of Karl Erik Hellström's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karl Erik Hellström with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karl Erik Hellström more than expected).

Fields of papers citing papers by Karl Erik Hellström

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karl Erik Hellström. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karl Erik Hellström. The network helps show where Karl Erik Hellström may publish in the future.

Co-authorship network of co-authors of Karl Erik Hellström

This figure shows the co-authorship network connecting the top 25 collaborators of Karl Erik Hellström. A scholar is included among the top collaborators of Karl Erik Hellström based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Karl Erik Hellström. Karl Erik Hellström is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	From the Hellstrom paradox toward cancer cure 2019 ·Progress in molecular biology and translational science ·Karl Erik Hellström, Ingegerd Hellström	13
2	An In Vitro Model That Predicts the Therapeutic Efficacy of Immunomodulatory Antibodies 2016 ·Journal of Immunotherapy ·Min Dai, (unknown), Ingegerd Hellström, Karl Erik Hellström	3
3	Detection of the HE4 protein in urine as a biomarker for ovarian neoplasms: Clinical correlates 2015 ·Gynecologic Oncology ·John B. Liao, (unknown), Elizabeth M. Swisher, Kathy Agnew, Karl Erik Hellström, Ingegerd Hellström	34
4	Curing Mice with Large Tumors by Locally Delivering Combinations of Immunomodulatory Antibodies 2014 ·Clinical Cancer Research ·Min Dai, (unknown), Ingegerd Hellström, Karl Erik Hellström	44
5	Two new biomarkers, mesothelin and HE4, for diagnosis of ovarian carcinoma 2011 ·Expert Opinion on Medical Diagnostics ·Ingegerd Hellström, Karl Erik Hellström	33
6	Cutting Edge: CD83 Regulates the Development of Cellular Immunity 2002 ·The Journal of Immunology ·Nathalie Scholler, Martha Hayden-Ledbetter, Amber Dahlin, Ingegerd Hellström, Karl Erik Hellström, Jeffrey A. Ledbetter	103
7	Amplification of tumor immunity by gene transfer of the co-stimulatory 4-1BB ligand: synergy with the CD28 co-stimulatory pathway 1998 ·European Journal of Immunology ·Ignacio Melero, (unknown), Karl Erik Hellström, Alejandro Aruffo, Robert S. Mittler, Lieping Chen	179
8	The role of B7-2 (CD86) in tumour immunity 1997 ·Expert Opinion on Investigational Drugs ·(unknown), Karl Erik Hellström, Lieping Chen	3
9	Cloning and Expression of the Gene for the Melanoma-Associated ME20 Antigen 1994 ·DNA and Cell Biology ·Grace A. Maresh, John Marken, Michael Neubauer, Alejandro Aruffo, Ingegerd Hellström, Karl Erik Hellström, Hans Marquardt	22
10	The biologic window for chimeric l6 radioimmunotherapy 1994 ·Cancer ·Sally J. DeNardo, Gary R. Mirick, Linda A. Kroger, L.F. O'Grady, Kent L. Erickson, Aina Yuan, Kathleen R. Lamborn, Ingegerd Hellström, Karl Erik Hellström, Gerald L. DeNardo	42
11	Dexamethasone Decreases the Delivery of Tumor-Specific Monoclonal Antibody to Both Intracerebral and Subcutaneous Tumor Xenografts 1993 ·Neurosurgery ·Edward A. Neuwelt, Peggy A. Barnett, Fred L. Ramsey, Ingegerd Hellström, Karl Erik Hellström, Christopher McCormick	5
12	Phase I trial of chimeric (human-mouse) monoclonal antibody L6 in patients with non-small-cell lung, colon, and breast cancer 1993 ·Cancer Immunology Immunotherapy ·Gary E. Goodman, Ingegerd Hellström, Dale E. Yelton, James L. Murray, (unknown), (unknown), (unknown), (unknown), Claude Nicaise, (unknown), Karl Erik Hellström	41
13	Possibilities for Active Immunotherapy of Human Cancer 1992 ·Cancer Investigation ·Karl Erik Hellström, Ingegerd Hellström	7
14	Generation of 5-fluorouracil from 5-fluorocytosine by monoclonal antibody-cytosine deaminase conjugates 1991 ·Bioconjugate Chemistry ·Peter D. Senter, P. P. Su, Tohoru Katsuragi, Takuo Sakai, W L Cosand, Ingegerd Hellström, Karl Erik Hellström	62
15	Antibody-penicillin-V-amidase conjugates kill antigen-positive tumor cells when combined with doxorubicin phenoxyacetamide 1990 ·Cancer Immunology Immunotherapy ·David E. Kerr, Peter D. Senter, William Burnett, David L. Hirschberg, Ingegerd Hellström, Karl Erik Hellström	49
16	Monoclonal antiidiotypic antibodies related to the p97 human melanoma antigen. 1989 ·PubMed ·Maria Kahn, Ingegerd Hellström, (unknown), Karl Erik Hellström	13
17	Increased Delivery of Tumor-specific Monoclonal Antibodies to Brain after Osmotic Blood-Brain Barrier Modification in Patients with Melanoma Metastatic to the Central Nervous System 1987 ·Neurosurgery ·Edward A. Neuwelt, (unknown), Peggy A. Barnett, Suellen A. Dahlborg, (unknown), Steven M. Larson, Paul H. Brown, Keith F. Eckerman, Karl Erik Hellström, Ingegerd Hellström	52
18	Melanoma localization in nude mice with monoclonal Fab against p97. 1985 ·PubMed ·Paul L. Beaumier, Kenneth A. Krohn, Jorge A. Carrasquillo, Janet F. Eary, Ingegerd Hellström, Karl Erik Hellström, Wil B. Nelp, Steven M. Larson	37
19	Workshop on Monoclonal Antibodies to Human Melanoma-Associated Antigens: Findings of the Seattle Group 1982 ·Hybridoma ·Ingegerd Hellström, Joseph P. Brown, Karl Erik Hellström	5
20	Lymphocyte-Mediated Cytotoxicity And Blocking Serum Activity To Tumor Antigens breakdown → 1974 ·Advances in immunology ·Karl Erik Hellström, Ingegerd Hellström	509

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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