John W. Regan

11.0k citations

142 papers · 9.2k indexed · 4 hit papers · h-index 47

Molecular Biology top 1%
Cellular and Molecular Neuroscience top 0.5%
Pharmacology top 0.2%
Physiology top 2%
Genetics top 2%

Co-authors: Robert J. Lefkowitz Hiromichi Fujino Marc G. Caron Brian K. Kobilka Tong Sun Kobilka Kristen L. Pierce Kiefer W. Daniel W. Daniel Stamer
Topics: Receptor Mechanisms and Signaling (63 papers)Inflammatory mediators and NSAID effects (46 papers)Estrogen and related hormone effects (28 papers)
Cited by: Cellular and Molecular Neuroscience Biochemistry Pharmacology
Journals: Science Proceedings of the National Academy of Sciences Nucleic Acids Research
Partner nations: United States Czechia Japan

In The Last Decade

John W. Regan

140 papers receiving 8.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cloning, Sequencing, and Expression of the Gene Coding for the Human Platelet α ₂ -Adrenergic Receptor

1987 677 citations Brian K. Kobilka, Marc G. Caron et al. profile →
Chimeric α ₂ -,β ₂ -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity

1988 636 citations Brian K. Kobilka, John W. Regan et al. profile →
Cloning and expression of a human kidney cDNA for an alpha 2-adrenergic receptor subtype.

1988 369 citations John W. Regan, Marc G. Caron et al. profile →
Site-directed mutagenesis of the cytoplasmic domains of the human beta 2-adrenergic receptor. Localization of regions involved in G protein-receptor coupling.

1988 337 citations John W. Regan, Marc G. Caron et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by John W. Regan

Since Specialization

Citations

This map shows the geographic impact of John W. Regan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John W. Regan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John W. Regan more than expected).

Fields of papers citing papers by John W. Regan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John W. Regan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John W. Regan. The network helps show where John W. Regan may publish in the future.

Co-authorship network of co-authors of John W. Regan

This figure shows the co-authorship network connecting the top 25 collaborators of John W. Regan. A scholar is included among the top collaborators of John W. Regan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John W. Regan. John W. Regan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Validation of the Fear and Avoidance of Memory Loss scale in community‐based older adults 2023 ·Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring ·Francesca R Farina,(unknown),(unknown),(unknown),(unknown),John W. Regan,(unknown),Marc Bennett,Bert Lenaert,James W. Griffith	5
2	Down-regulation of the expression of cyclooxygenase-2 and prostaglandin E2 by interleukin-4 is mediated via a reduction in the expression of prostanoid EP4 receptors in HCA-7 human colon cancer cells 2022 ·European Journal of Pharmacology ·(unknown),(unknown),Keijo Fukushima,Yuki Nakano,John W. Regan,Masato Mashimo,Hiromichi Fujino	4
3	Induction of Angiogenic Immediate Early Genes by Activation of FP Prostanoid Receptors in Cultured Human Ciliary Smooth Muscle Cells 2010 ·Current Eye Research ·Anthony J. Hutchinson,(unknown),Chih-Ling Chou,Wei Xu,W. Daniel Stamer,David F. Woodward,John W. Regan	11
4	EP3 prostanoid receptor isoforms utilize distinct mechanisms to regulate ERK 1/2 activation 2009 ·Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Davelene D. Israel,John W. Regan	28
5	Indomethacin decreases EP2 prostanoid receptor expression in colon cancer cells 2007 ·Biochemical and Biophysical Research Communications ·Hiromichi Fujino,(unknown),John W. Regan,Toshihiko Murayama	25
6	Enzymes and Receptors of Prostaglandin Pathways with Arachidonic Acid-derived Versus Eicosapentaenoic Acid-derived Substrates and Products* 2007 ·Journal of Biological Chemistry ·M. Wada,Cynthia J. DeLong,Yu Hong,Caroline Jill Rieke,In‐Seok Song,Ranjinder S. Sidhu,Chong Yuan,Mark Warnock,Alvin H. Schmaier,Chieko Yokoyama,Emer M. Smyth,Stephen J. Wilson,Garret A. FitzGerald,R. Michael Garavito,(unknown),John W. Regan,William L. Smith	321
7	Differential Regulation of Phosphorylation of the cAMP Response Element-Binding Protein after Activation of EP2 and EP4 Prostanoid Receptors by Prostaglandin E2 2005 ·Molecular Pharmacology ·Hiromichi Fujino,(unknown),John W. Regan	137
8	Prostaglandin E2 Selectively Antagonizes Prostaglandin F2α-stimulated T-cell Factor/β-Catenin Signaling Pathway by the FPB Prostanoid Receptor 2004 ·Journal of Biological Chemistry ·Hiromichi Fujino,George Vielhauer,John W. Regan	9
9	EP2 and EP4 prostanoid receptor signaling 2003 ·Life Sciences ·John W. Regan	363
10	Prostaglandin E2 Induced Functional Expression of Early Growth Response Factor-1 by EP4, but Not EP2, Prostanoid Receptors via the Phosphatidylinositol 3-Kinase and Extracellular Signal-regulated Kinases 2003 ·Journal of Biological Chemistry ·Hiromichi Fujino,Wei Xu,John W. Regan	263
11	Alpha-2 adrenergic receptors stimulate actin organization in developing fetal rat cardiac myocytes 2003 ·Life Sciences ·Amy C. Porter,Samuel Svensson,W. Daniel Stamer,Joseph J. Bahl,Jeremy G. Richman,John W. Regan	14
12	Differential Internalization of the Prostaglandin F2α Receptor Isoforms: Role of Protein Kinase C and Clathrin 2002 ·Journal of Pharmacology and Experimental Therapeutics ·Dinesh Kumar Srinivasan,Hiromichi Fujino,John W. Regan	26
13	Activation of FP Prostanoid Receptor Isoforms Leads to Rho-mediated Changes in Cell Morphology and in the Cell Cytoskeleton 1999 ·Journal of Biological Chemistry ·Kristen L. Pierce,Hiromichi Fujino,Dinesh Kumar Srinivasan,John W. Regan	95
14	Ovine Prostaglandin F<sub>2α</sub> Receptor: Steroid Influence on Steady-State Levels of Luteal mRNA 1999 ·Endocrine ·Patricia B. Hoyer,Samuel L. Marion,(unknown),Bo R. Rueda,Debora L. Hamernik,John W. Regan,Mark E. Wise	4
15	6-isopropoxy-9-oxoxanthene-2-carboxylic acid (AH 6809), a human EP2 receptor antagonist 1995 ·Biochemical Pharmacology ·(unknown),(unknown),Thomas H. Burkey,John W. Regan	96
16	Molecular Characterization and Ocular Hypotensive Properties of the Prostanoid EP ₂ Receptor 1995 ·Journal of Ocular Pharmacology and Therapeutics ·David F. Woodward,A M Bogardus,John E. Donello,Craig Fairbairn,Daniel W. Gil,Karen M. Kedzie,(unknown),A. Kharlamb,(unknown),Steven W. Andrews,Kristen L. Pierce,John W. Regan	24
17	Comparison of mRNA levels for the PGF2α receptor (FP) during luteolysis and early pregnancy in the ovine corpus luteum 1995 ·Endocrine ·Bo R. Rueda,Ihab W. Botros,Kristen L. Pierce,John W. Regan,Patricia B. Hoyer	23
18	Differential expression of two α2-adrenergic receptor subtype mRNAs in human tissues 1992 ·Molecular Brain Research ·Merja Perälä,Harri Hirvonen,Hannu Kalimo,(unknown),John W. Regan,Karl E.O. Åkerman,Mika Scheinin	33
19	Molecular Biology of Adrenergic Receptors 1988 ·Cold Spring Harbor Symposia on Quantitative Biology ·Robert J. Lefkowitz,Brian K. Kobilka,J.L. Benovic,Michel Bouvier,Susanna Cotecchia,William P. Hausdorff,Henrik Dohlman,John W. Regan,Marc G. Caron	24
20	DNA replication in human cells treated with methyl methanesulfonate 1973 ·Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis ·S N Buhl,John W. Regan	37

About John W. Regan

John W. Regan is a scholar working on Pharmacology, Biochemistry and Cellular and Molecular Neuroscience, having authored 142 papers that have together received 9.2k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (63 papers), Inflammatory mediators and NSAID effects (46 papers) and Estrogen and related hormone effects (28 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (3.1k citations), Biochemistry (808 citations) and Pharmacology (1.9k citations). John W. Regan has collaborated with scholars based in United States, Czechia and Japan. Frequent co-authors include Robert J. Lefkowitz, Hiromichi Fujino, Marc G. Caron, Brian K. Kobilka, Tong Sun Kobilka, Kristen L. Pierce, Kiefer W. Daniel, W. Daniel Stamer, Teresa L. Yang‐Feng and Andrea J. Yool. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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