John C. Kappes

20.3k citations

163 papers · 13.8k indexed · 6 hit papers · h-index 54

Impact in

Virology top 0.02%
- HIV Research and Treatment
Infectious Diseases top 0.1%
- HIV/AIDS drug development and treatment
- HIV/AIDS Research and Interventions

Papers in

Virology 106
- HIV Research and Treatment 106
Infectious Diseases 48
- HIV/AIDS drug development and treatment 42
- HIV/AIDS Research and Interventions 16

Co-authors: George M. Shaw Beatrice H. Hahn Xiaoyun Wu Julie M. Decker Michael S. Saag Xiping Wei J Michael Kilby Christina Ochsenbauer
Journals: Journal of Virology (46 papers)PLoS ONE (12 papers)AIDS Research and Human Retroviruses (5 papers)The Journal of Immunology (4 papers)Virology (4 papers)
Partner nations: United States United Kingdom China

In The Last Decade

John C. Kappes

157 papers receiving 13.5k citations

Hit Papers

6 papers align trajectories log scale

Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling 2008 · 523 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2008 Journal of Biological Chemistry
2003 Nature
2002 Antimicrobial Agents and Chemotherapy
2000 Journal of Virology
1993 Science
1991 New England Journal of Medicine

Peers

Countries citing papers authored by John C. Kappes

Since Specialization

Citations

This map shows the geographic impact of John C. Kappes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John C. Kappes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John C. Kappes more than expected).

Fields of papers citing papers by John C. Kappes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. Kappes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. Kappes. The network helps show where John C. Kappes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John C. Kappes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John C. Kappes Line = papers co-authored together John C. Kappes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Microbial remodeling of gut tryptophan metabolism and indole-3-lactate production regulate epithelial barrier repair and viral suppression in human and simian immunodeficiency virus infections Mucosal Immunology ·Clarissa Santos Rocha, Katie L. Alexander, Carolina Herrera, Hui Pei, Irina Grishina, Lauren A. Hirao, Virana Zuhda Rahmawati, Juan Arredondo, 高史松原, Tomas Jakoubek, Anne Fenton, Maria L. Marco, David A. Mills, John C. Kappes, Lesley E. Smythies, Paul Ziprin, Sumathi Sankaran‐Walters, Phillip D. Smith, Satya Dandekar	2025	6
2	Characterization of full-length and cytoplasmic tail-truncated envelope glycoproteins incorporated into human immunodeficiency virus (HIV-1) virions and virus-like particles Journal of Virology ·Saumya Anang, Shijian Zhang, Andrew J. Yuhas, Haitao Ding, Ashlesha Deshpande, Hanh T. Nguyen, John C. Kappes, Joseph Sodroski	2025	0
3	Conformations of Human Immunodeficiency Virus Envelope Glycoproteins in Detergents and Styrene-Maleic Acid Lipid Particles Journal of Virology ·N. Ruiz Amador, Shijian Zhang, Hanh T. Nguyen, Haitao Ding, 守正花谷, John C. Kappes, Amos B. Smith, Joseph Sodroski	2023	7
4	Folding correctors can restore CFTR posttranslational folding landscape by allosteric domain–domain coupling Nature Communications ·Naoto Soya, Haijin Xu, Ariel Roldán, Zhengrong Yang, David Legge, Fan Jiang, Huang En-jie, Guido Veit, Susan P.C. Cole, John C. Kappes, Tamás Hegedűs, Gergely L. Lukács	2023	16
5	Detection of the HIV-1 Accessory Proteins Nef and Vpu by Flow Cytometry Represents a New Tool to Study Their Functional Interplay within a Single Infected CD4 ⁺ T Cell Journal of Virology ·Jérémie Prévost, Jonathan Richard, Romain Gasser, Halima Medjahed, Frank Kirchhoff, Beatrice H. Hahn, John C. Kappes, Christina Ochsenbauer, Ralf Duerr, Andrés Finzi	2022	8
6	Functional and Highly Cross-Linkable HIV-1 Envelope Glycoproteins Enriched in a Pretriggered Conformation Journal of Virology ·Hanh T. Nguyen, 健澤木, Saumya Anang, F. Ricci, Shitao Zou, N. Ruiz Amador, Qian Wang, Shijian Zhang, Ashlesha Deshpande, Haitao Ding, クセニアマリュニナ, Amos B. Smith, John C. Kappes, Joseph Sodroski	2022	14
7	Growth hormone (GH) receptor (GHR)-specific inhibition of GH-Induced signaling by soluble IGF-1 receptor (sol IGF-1R) Molecular and Cellular Endocrinology ·Yue Zhang, 哲中橋, Sweta B. Patel, Ying Liu, Andrew J. Paterson, John C. Kappes, Jing Jiang, Stuart J. Frank	2019	6
8	The Cystic Fibrosis Transmembrane Conductance Regulator Potentiator Ivacaftor Augments Mucociliary Clearance Abrogating Cystic Fibrosis Transmembrane Conductance Regulator Inhibition by Cigarette Smoke American Journal of Respiratory Cell and Molecular Biology ·S. Vamsee Raju, Vivian Lin, L. Almandoz, Carmel M. McNicholas, Suman Karki, Peter A. Sloane, Liping Tang, Patricia L. Jackson, Wei Wang, Landon Wilson, Kevin Macon, Marina Mazur, John C. Kappes, Lawrence J. DeLucas, Stephen J. Barnes, Kevin L. Kirk, Guillermo J. Tearney, Steven M. Rowe	2016	78
9	In Vivo Activation of Human NK Cells by Treatment with an Interleukin-15 Superagonist Potently Inhibits Acute In Vivo HIV-1 Infection in Humanized Mice Journal of Virology ·额尔顿, Candice D. Church, Jian Zheng, Chai-Doo Lee, Christina Ochsenbauer, John C. Kappes, Bai Liu, Emily K. Jeng, Hing C. Wong, Harris Goldstein	2015	74
10	Optimized Replicating Renilla Luciferase Reporter HIV-1 Utilizing Novel Internal Ribosome Entry Site Elements for Native Nef Expression and Function AIDS Research and Human Retroviruses ·Michael O. Alberti, P. Erre, Allison E. Burnett, Haitao Ding, Rakesh K. Bakshi, Tara G. Edmonds, John C. Kappes, Christina Ochsenbauer	2015	24
11	A survey of detergents for the purification of stable, active human cystic fibrosis transmembrane conductance regulator (CFTR) Biochimica et Biophysica Acta (BBA) - Biomembranes ·Ellen Hildebrandt, Qinghai Zhang, Chang Ye Hui, Haitao Ding, Qun Dai, Lingling Peng, Yu Fu, Lawrence J. DeLucas, Robert C. Ford, John C. Kappes, Ina L. Urbatsch	2014	16
12	Short Communication: HIV Type 1 Escapes Inactivation by Saliva via Rapid Escape into Oral Epithelial Cells AIDS Research and Human Retroviruses ·Elizabeth A. Dietrich, Kristin Gebhard, Claudine E. Fasching, Rodrigo A. Giacaman, John C. Kappes, Karen F. Ross, Mark C. Herzberg	2011	8
13	GP41-Specific Antibody Blocks Cell-Free HIV Type 1 Transcytosis through Human Rectal Mucosa and Model Colonic Epithelium The Journal of Immunology ·Ruizhong Shen, Ernesto Drelichman, Diane Bimczok, Christina Ochsenbauer, John C. Kappes, Jamie A. Cannon, Daniela Tudor, Morgane Bomsel, Lesley E. Smythies, Phillip D. Smith	2010	50
14	Uterine Epithelial Cell Regulation of DC-SIGN Expression Inhibits Transmitted/Founder HIV-1 Trans Infection by Immature Dendritic Cells PLoS ONE ·Daniel Ochiel, Christina Ochsenbauer, John C. Kappes, Mimi Ghosh, John V. Fahey, Charles R. Wira	2010	32
15	COP9-Associated CSN5 Regulates Exosomal Protein Deubiquitination and Sorting American Journal Of Pathology ·Yuelong Liu, Spandan V. Shah, Xiaoyu Xiang, Jianhua Wang, Zhong-Bin Deng, Cunren Liu, Liming Zhang, Jianming Wu, Tara G. Edmonds, James S Baumgartner, John C. Kappes, Huang-Ge Zhang	2009	57
16	Oxidative Stress Induces Vascular Calcification through Modulation of the Osteogenic Transcription Factor Runx2 by AKT Signaling Journal of Biological Chemistry ·Chang Hyun Byon, Amjad Javed, Qun Dai, John C. Kappes, Thomas L. Clemens, Victor Darley‐Usmar, Jay M. McDonald, Yabing Chen Hit paper breakdown →	2008	523
17	Expansion of Spleen Myeloid Suppressor Cells Represses NK Cell Cytotoxicity in Tumor Bearing Host (49.13) The Journal of Immunology ·Cunren Liu, Shaohua Yu, Kurt R. Zinn, Jianhua Wang, William E. Grizzle, John C. Kappes, Huang‐Ge Zhang	2007	17
18	Suppression of breast cancer metastasis by p16’s dual effect on anti-angiogenesis and anti-proliferation Cancer Research ·Kevin T. Nash, Pushkar Phadke, Kedar S. Vaidya, Yujiang Jia, Junmin Zhang, John C. Kappes, Mary Ann Accavitti-Loper, Douglas R. Hurst, Danny R. Welch	2006	1
19	Murine Mammary Carcinoma Exosomes Promote Tumor Growth by Suppression of NK Cell Function The Journal of Immunology ·Cunren Liu, Shaohua Yu, Kurt R. Zinn, Jianhua Wang, Liming Zhang, Yujiang Jia, John C. Kappes, Stephen Barnes, Robert P. Kimberly, William E. Grizzle, Huang‐Ge Zhang	2006	408
20	Antibody to Herpes Simplex Virus (HSV) ICP-35 Proteins After HSV Challenge of Animals Immunized with HSV Subunit Vaccines The Journal of Infectious Diseases ·David I. Bernstein, Lawrence R. Stanberry, John C. Kappes, Rae Lyn Burke, Martin G. Myers	1988	7

About John C. Kappes

John C. Kappes is a scholar working on Virology, Infectious Diseases, Immunology, Epidemiology and Emergency Medicine, having authored 163 papers that have together received 13.8k indexed citations. Recurring topics across this work include HIV Research and Treatment (106 papers), HIV/AIDS drug development and treatment (42 papers), Immune Cell Function and Interaction (37 papers), Virus-based gene therapy research (18 papers), Herpesvirus Infections and Treatments (17 papers), HIV/AIDS Research and Interventions (16 papers), Cytomegalovirus and herpesvirus research (16 papers) and Monoclonal and Polyclonal Antibodies Research (14 papers). The work is most often cited by research in Virology (8.8k citations), Infectious Diseases (4.9k citations), Immunology (4.7k citations), Epidemiology (2.7k citations) and Hepatology (468 citations). John C. Kappes has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include George M. Shaw, Beatrice H. Hahn, Xiaoyun Wu, Julie M. Decker, Michael S. Saag, Xiping Wei, J Michael Kilby, Christina Ochsenbauer, Stephen J. Clark and Hongmei Liu. Their work appears in journals such as Journal of Virology, PLoS ONE, AIDS Research and Human Retroviruses, The Journal of Immunology and Virology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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