John B. Hynes

1.6k total citations
89 papers, 1.3k citations indexed

About

John B. Hynes is a scholar working on Organic Chemistry, Molecular Biology and Rheumatology. According to data from OpenAlex, John B. Hynes has authored 89 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Organic Chemistry, 46 papers in Molecular Biology and 10 papers in Rheumatology. Recurrent topics in John B. Hynes's work include Quinazolinone synthesis and applications (31 papers), Synthesis and Characterization of Heterocyclic Compounds (29 papers) and Biochemical and Molecular Research (26 papers). John B. Hynes is often cited by papers focused on Quinazolinone synthesis and applications (31 papers), Synthesis and Characterization of Heterocyclic Compounds (29 papers) and Biochemical and Molecular Research (26 papers). John B. Hynes collaborates with scholars based in United States, Netherlands and Canada. John B. Hynes's co-authors include Jan H. Schornagel, James H. Freisheim, Gerrit Jansen, Wallace T. Ashton, Joseph R. Bertino, S Rijnboutt, George Posthuma, Ger J. Strous, A. Rosowsky and Kevin J. Scanlon and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and The Journal of Cell Biology.

In The Last Decade

John B. Hynes

85 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
John B. Hynes United States 18 667 454 180 165 135 89 1.3k
Ronald A. Forsch United States 19 510 0.8× 457 1.0× 128 0.7× 114 0.7× 150 1.1× 52 1.0k
Y. Gaumont United States 18 619 0.9× 442 1.0× 202 1.1× 133 0.8× 133 1.0× 65 1.1k
Joseph I. DeGraw United States 19 560 0.8× 583 1.3× 96 0.5× 211 1.3× 92 0.7× 108 1.4k
Robert Westwood United Kingdom 19 526 0.8× 677 1.5× 55 0.3× 129 0.8× 73 0.5× 54 1.3k
Robert W. Chambers United States 23 912 1.4× 224 0.5× 27 0.1× 78 0.5× 71 0.5× 62 1.3k
Kathryn White United States 23 745 1.1× 400 0.9× 251 1.4× 167 1.0× 145 1.1× 38 1.3k
Keiko Kuroda Japan 18 254 0.4× 268 0.6× 237 1.3× 62 0.4× 21 0.2× 63 1.0k
Takeshi Seno Japan 24 1.7k 2.5× 82 0.2× 178 1.0× 452 2.7× 84 0.6× 76 2.0k
Jean‐Michel Chezal France 22 590 0.9× 856 1.9× 85 0.5× 270 1.6× 37 0.3× 121 1.9k
Hon‐Wah Man United States 17 784 1.2× 412 0.9× 68 0.4× 277 1.7× 50 0.4× 24 1.5k

Countries citing papers authored by John B. Hynes

Since Specialization
Citations

This map shows the geographic impact of John B. Hynes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John B. Hynes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John B. Hynes more than expected).

Fields of papers citing papers by John B. Hynes

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John B. Hynes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John B. Hynes. The network helps show where John B. Hynes may publish in the future.

Co-authorship network of co-authors of John B. Hynes

This figure shows the co-authorship network connecting the top 25 collaborators of John B. Hynes. A scholar is included among the top collaborators of John B. Hynes based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John B. Hynes. John B. Hynes is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Westerhof, G R, Jan H. Schornagel, Ietje Kathmann, et al.. (1995). Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.. Molecular Pharmacology. 48(3). 459–471. 173 indexed citations
2.
Hynes, John B., et al.. (1993). Synthesis and Biological Evaluation of Analogues of 5,8-Dideazaisofolic Acid (IAHQ) Modified at Positions 2, 4 and 9. Advances in experimental medicine and biology. 338. 417–420. 1 indexed citations
3.
Hynes, John B., et al.. (1992). Inhibition of hog liver folylpolyglutamate synthetase by 5-substituted 5,8-dideaza analogs of folic acid bearing a terminal L-ornithine residue. Journal of Medicinal Chemistry. 35(22). 4078–4085. 10 indexed citations
4.
Cesar, Denise, et al.. (1991). In vitro metabolism of 5,8-dideazafolates and 5,8-dideazaisofolates by mammalian folylpoly- γ-glutamate synthetase. Biochemical Pharmacology. 42(4). 833–838. 13 indexed citations
5.
Duch, David S., et al.. (1991). Studies on the mechanism of antitumor action of 2-desamino-2-methyl-5,8-dideazaisofolic acid. Biochemical Pharmacology. 41(5). 781–787. 13 indexed citations
6.
Hynes, John B., G R Westerhof, Gerrit Jansen, et al.. (1991). Synthesis and biological evaluation of a fluorescent analog of folic acid. Biochemistry. 30(23). 5674–5681. 30 indexed citations
7.
Hynes, John B., et al.. (1990). Synthesis and preliminary biological evaluation of 5‐fluoro‐5,8‐dideazaisoaminopterin. Journal of Heterocyclic Chemistry. 27(7). 2081–2084. 4 indexed citations
8.
9.
Rosowsky, A., James H. Freisheim, John B. Hynes, et al.. (1989). Tricyclic 2,4-diaminopyrimidines with broad antifolate activity and the ability to inhibit pneumocystis carinii growth in cultured human lung fibroblasts in the presence of leucovorin. Biochemical Pharmacology. 38(16). 2677–2684. 12 indexed citations
10.
Hynes, John B., et al.. (1989). Comparison of the biological effects of selected 5,8-dideazafolate analogs with their 2-desamino counterparts. Journal of Medicinal Chemistry. 32(4). 852–856. 9 indexed citations
11.
Ferguson, Karen A., Diane H. Boschelli, Philip Hoffman, et al.. (1989). Synergy between 5,10-dideaza-5,6,7,8-tetrahydrofolic acid and methotrexate in mice bearing L1210 tumors. Cancer Chemotherapy and Pharmacology. 25(3). 173–176. 5 indexed citations
12.
Cichowicz, David J., John B. Hynes, & Barry Shane. (1988). Substrate specificity of mammalian folylpoly-γ-glutamate synthetase for 5,8-dideazafolates and 5,8-dideaza analogues of aminopterin. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology. 957(3). 363–369. 11 indexed citations
13.
Smith, Gary K., et al.. (1988). Inhibition of chicken liver 5-aminoimidazole-4-carboxamide ribonucleotide transformylase by 5,8-dideaza analogues of folic acid. Biochemical Pharmacology. 37(3). 449–451. 3 indexed citations
14.
Hynes, John B., et al.. (1985). Chemistry and antitumor evaluation of selected classical 2,4-diaminoquinazoline analogs of folic acid. Journal of Medicinal Chemistry. 28(2). 209–215. 21 indexed citations
15.
Tsang, Kwong-Yok, John B. Hynes, H. Hugh Fudenberg, & Jiayi Pan. (1984). Effects of Three New Folate Antagonists on Human Breast Adenocarcinoma Cells in vitro and on Immune Responses in vivo. Chemotherapy. 30(1). 61–68.
16.
Scanlon, Kevin J., Barbara A. Moroson, J.R. Bertino, & John B. Hynes. (1979). Quinazoline Analogues of Folic Acid as Inhibitors of Thymidylate Synthetase from Bacterial and Mammalian Sources. Molecular Pharmacology. 16(1). 261–269. 21 indexed citations
17.
Hynes, John B., et al.. (1977). Quinazolines as inhibitors of dihydrofolate reductase. 4. Classical analogs of folic and isofolic acids. Journal of Medicinal Chemistry. 20(4). 588–591. 35 indexed citations
18.
Hynes, John B.. (1970). Hydroxylamine derivatives as potential antimalarial agents. 1. Hydroxamic acids. Journal of Medicinal Chemistry. 13(6). 1235–1237. 17 indexed citations
19.
Sawodny, W., Kurt Niedenzu, John B. Hynes, & John W Dawson. (1967). Vibrational spectra of trihalogeno-s-triazines C3F3−nClnN3. Spectrochimica Acta Part A Molecular Spectroscopy. 23(5). 1327–1334. 4 indexed citations
20.
Gale, Glen R., et al.. (1962). PHARMACOLOGY OF CERTAIN ANTIMICROBIAL N1,N5-SUBSTITUTED BIGUANIDES. Journal of Pharmacology and Experimental Therapeutics. 138(2). 277–284. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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