A. Rosowsky

106.8k total citations · 1 hit paper
235 papers, 5.4k citations indexed

About

A. Rosowsky is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, A. Rosowsky has authored 235 papers receiving a total of 5.4k indexed citations (citations by other indexed papers that have themselves been cited), including 125 papers in Organic Chemistry, 87 papers in Molecular Biology and 45 papers in Infectious Diseases. Recurrent topics in A. Rosowsky's work include Synthesis and Characterization of Heterocyclic Compounds (55 papers), HIV/AIDS drug development and treatment (44 papers) and Synthesis and Biological Evaluation (37 papers). A. Rosowsky is often cited by papers focused on Synthesis and Characterization of Heterocyclic Compounds (55 papers), HIV/AIDS drug development and treatment (44 papers) and Synthesis and Biological Evaluation (37 papers). A. Rosowsky collaborates with scholars based in United States, Netherlands and France. A. Rosowsky's co-authors include Ronald A. Forsch, Sherry F. Queener, Edward J. Modest, Emil Frei, Joel E. Wright, Carol A. Cucchi, E Frei, William D. Ensminger, Beverly A. Teicher and Vic Raso and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Journal of Biological Chemistry.

In The Last Decade

A. Rosowsky

232 papers receiving 5.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A clinical-pharmacological evaluation of hepatic arterial infusions of 5-fluoro-2'-deoxyuridine and 5-fluorouracil.

1978 414 citations William D. Ensminger, A. Rosowsky et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
A. Rosowsky United States	37	2.3k	1.8k	1.1k	668	645	235	5.4k
A. D’Arcy Switzerland	41	4.0k 1.7×	619 0.4×	932 0.8×	472 0.7×	518 0.8×	61	7.0k
Thomas Peters Germany	43	4.4k 1.9×	1.4k 0.8×	443 0.4×	584 0.9×	194 0.3×	161	7.4k
Gerald Zon United States	54	6.4k 2.8×	1.8k 1.0×	916 0.8×	582 0.9×	213 0.3×	207	9.3k
Thomas Meyer Switzerland	45	3.7k 1.6×	1.2k 0.7×	2.2k 1.9×	150 0.2×	237 0.4×	137	7.9k
Dirk B. Mendel United States	43	4.2k 1.8×	772 0.4×	1.3k 1.2×	541 0.8×	173 0.3×	74	8.0k
Jerry M. Collins United States	52	2.7k 1.2×	341 0.2×	3.1k 2.8×	804 1.2×	637 1.0×	176	9.0k
Gertrude B. Elion United States	55	5.4k 2.4×	1.5k 0.8×	1.7k 1.6×	2.0k 3.1×	1.5k 2.4×	176	13.0k
Kees Nooter Netherlands	52	3.9k 1.7×	428 0.2×	5.4k 4.8×	609 0.9×	419 0.6×	149	9.1k
Melinda G. Hollingshead United States	45	3.9k 1.7×	1.1k 0.6×	1.9k 1.7×	301 0.5×	206 0.3×	167	6.9k
Giovanni Maga Italy	51	5.5k 2.4×	2.4k 1.4×	937 0.8×	2.2k 3.3×	423 0.7×	270	9.9k

Countries citing papers authored by A. Rosowsky

Since Specialization

Citations

This map shows the geographic impact of A. Rosowsky's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by A. Rosowsky with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites A. Rosowsky more than expected).

Fields of papers citing papers by A. Rosowsky

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by A. Rosowsky. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by A. Rosowsky. The network helps show where A. Rosowsky may publish in the future.

Co-authorship network of co-authors of A. Rosowsky

This figure shows the co-authorship network connecting the top 25 collaborators of A. Rosowsky. A scholar is included among the top collaborators of A. Rosowsky based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with A. Rosowsky. A. Rosowsky is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Rosowsky, A., Ronald A. Forsch, Carol Hopkins Sibley, Clark B. Inderlied, & Sherry F. Queener. (2004). New 2,4-Diamino-5-(2‘,5‘-substituted benzyl)pyrimidines as Potential Drugs against Opportunistic Infections of AIDS and Other Immune Disorders. Synthesis and Species-Dependent Antifolate Activity. Journal of Medicinal Chemistry. 47(14). 3705–3705. 3 indexed citations

Wright, Joel E., et al.. (2004). Synthesis and antifolate activity of new pyrrolo[2,3‐d]pyrimidine and thieno[2,3‐d]pyrimidine inhibitors of dihydrofolate reductase. Journal of Heterocyclic Chemistry. 41(5). 787–793. 4 indexed citations

Peters, Godefridus J., David G. Priest, Yehuda G. Assaraf, et al.. (2002). Multiple mechanisms of resistance to methotrexate and novel antifolates in human CCRF-CEM leukemia cells and their implications for folate homeostasis. Biochemical Pharmacology. 63(2). 105–115. 49 indexed citations

Nelson, Richard G. & A. Rosowsky. (2002). Dicyclic and Tricyclic Diaminopyrimidine Derivatives as Potent Inhibitors of Cryptosporidium parvum Dihydrofolate Reductase: Structure-Activity and Structure-Selectivity Correlations. Antimicrobial Agents and Chemotherapy. 46(3). 940–940. 16 indexed citations

Forsch, Ronald A., Henry Bader, & A. Rosowsky. (1999). Synthesis of L-2-(N-Pteroylamino )-3-(N -phosphonoacetyl)aminopropanoic Acid as an Analogue of the Putative Phosphorylated Intermediate in the γ-Glutamation of Folic Acid by Folylpolyglutamate Synthetase. Pteridines. 10(1). 39–46. 1 indexed citations

Rosowsky, A., Ronald A. Forsch, Sherry F. Queener, & Joseph R. Bertino. (1997). Synthesis of 2,4-Diaminopteridines with Bulky Lipophilic Groups at the 6-Position as Inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mammalian Dihydrofolate Reductase. Pteridines. 8(3). 173–187. 6 indexed citations

Holden, Sylvia A., Beverly A. Teicher, Michael F. Robinson, David Northey, & A. Rosowsky. (1995). Antifolates can potentiate topoisomerase II inhibitors in vitro and in vivo. Cancer Chemotherapy and Pharmacology. 36(2). 165–171. 14 indexed citations

Rosowsky, A., Ronald A. Forsch, Richard G. Moran, & James H. Freisheim. (1990). Synthesis and In Vitro Biological Evaluation of β,γ-Methano Analogues of Methotrexate and Aminopterin. Pteridines. 2(3). 133–139. 4 indexed citations

Rosowsky, A., Henry Bader, & Ronald A. Forsch. (1989). Synthesis of the Folylpolyglutamate Synthetase Inhibitor Nα-Pteroyl-Lornithine and its Nδ-Benzoyl and Nδ-Hemiphthaloyl Derivatives, and an Improved Synthesis of Nα-( 4-Amino-4-deoxypteroy1)-Nδ-hemiphthaloyl-Lornithine. Pteridines. 1(2). 91–98. 15 indexed citations

10.

Rosowsky, A., et al.. (1987). Methotrexate analogs. 30. Dihydrofolate reductase inhibition and in vitro tumor cell growth inhibition by N.epsilon.-(haloacetyl)-L-lysine and N.delta.-(haloacetyl)-L-ornithine analogs and an acivicin analog of methotrexate. Journal of Medicinal Chemistry. 30(8). 1463–1469. 8 indexed citations

11.

Rosowsky, A., Herbert T. Abelson, G. Peter Beardsley, et al.. (1982). Pharmacologic studies on the dibutyl and ?-monobutyl esters of methotrexate in the rhesus monkey. Cancer Chemotherapy and Pharmacology. 10(1). 55–61. 8 indexed citations

12.

Warren, Joseph D., et al.. (1980). A PREPARATIVE SCALE SYNTHESIS AND CHROMATOGRAPHIC SEPARATION OF METHOTREXATE-α AND γ-MONOBUTYL ESTERS. Organic Preparations and Procedures International. 12(3-4). 191–195. 4 indexed citations

13.

Ensminger, William D., et al.. (1978). Comparative effects of citrovorum factor and carboxypeptidase G1 on cerebrospinal fluid-methotrexate pharmacokinetics.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 62(10). 1549–52. 15 indexed citations

14.

Rosowsky, A., et al.. (1978). Methotrexate analogs. 11. Unambiguous chemical synthesis and in vitro biological evaluation of .alpha.- and .gamma.-monoesters as potential prodrugs. Journal of Medicinal Chemistry. 21(4). 380–386. 32 indexed citations

15.

Rosowsky, A., et al.. (1977). Prevention of methotrexate toxicity with thymidine esters or thymidine/thymine plus diazouracil. Abstr.. The Mouseion at the JAXlibrary (Jackson Laboratory). 1 indexed citations

16.

Rosowsky, A., et al.. (1974). Pteridines. III. Unexpected facile ring closure of 2-amino-6-phenethylpteridin-4(3H)-one in the presence of fluorosulfonic acid. The Journal of Organic Chemistry. 39(9). 1248–1250. 1 indexed citations

17.

Rosowsky, A.. (1972). Seven-membered heterocyclic compounds containing oxygen and sulfur. Wiley-Interscience eBooks. 7 indexed citations

18.

Rosowsky, A., et al.. (1968). Synthesis of new chlorine-substituted derivatives of 2-tetralone. The Journal of Organic Chemistry. 33(11). 4288–4290. 20 indexed citations

19.

Crocker, Allen C., Gordon F. Vawter, Edward B. D. Neuhauser, & A. Rosowsky. (1965). WOLMAN'S DISEASE: THREE NEW PATIENTS WITH A RECENTLY DESCRIBED LIPIDOSIS. PEDIATRICS. 35(4). 627–640. 61 indexed citations

20.

Rosowsky, A., et al.. (1964). Quinazolines. I. Formation of a Guanidinoquinazoline during the Three-Component Synthesis of a 4,6-Diamino-1-aryl-1,2-dihydro-s-triazine¹. The Journal of Organic Chemistry. 29(10). 2881–2887. 9 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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