John A. Timbrell

9.0k citations

125 papers · 6.5k indexed · 3 hit papers · h-index 34

Impact in

Pharmacology top 0.1%
- Drug-Induced Hepatotoxicity and Protection
- Pharmacogenetics and Drug Metabolism
Health, Toxicology and Mutagenesis top 1%
- Heavy Metal Exposure and Toxicity

Papers in

Pharmacology 42
- Drug-Induced Hepatotoxicity and Protection 31
- Pharmacogenetics and Drug Metabolism 21
Cell Biology 35
- Aldose Reductase and Taurine 24
- Muscle metabolism and nutrition 13

Co-authors: George Fotakis Catherine J. Waterfield Jeremy K. Nicholson Wayne R. Snodgrass P J Sadler Jerry R. Mitchell Sidney D. Nelson Vítor Seabra
Journals: Archives of Toxicology (16 papers)Biochemical Society Transactions (7 papers)Toxicology in Vitro (7 papers)Toxicology (6 papers)Biochemical Pharmacology (6 papers)
Partner nations: United Kingdom United States Portugal

In The Last Decade

John A. Timbrell

124 papers receiving 6.1k citations

Hit Papers

align trajectories log scale

In vitro cytotoxicity assays: Comparison of LDH, neutral red, MTT and protein assay in hepatoma cell lines following exposure to cadmium chloride 2005 · 1.2k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 Toxicology Letters
1981 Biochemical Society Transactions
1976 Annals of Internal Medicine

Peers

Countries citing papers authored by John A. Timbrell

Since Specialization

Citations

This map shows the geographic impact of John A. Timbrell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John A. Timbrell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John A. Timbrell more than expected).

Fields of papers citing papers by John A. Timbrell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John A. Timbrell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John A. Timbrell. The network helps show where John A. Timbrell may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John A. Timbrell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John A. Timbrell Line = papers co-authored together John A. Timbrell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The toxicity of extracts of plant parts ofMoringa stenopetala in HEPG2 cellsIn vitro Phytotherapy Research ·Tábata Apablaza, Peter J. Houghton, John A. Timbrell	2005	24
2	Methionine synthase activity and sulphur amino acid levels in the rat liver tumour cells HTC and Phi-1 Biochemical Pharmacology ·Susan H. Kenyon, Catherine J. Waterfield, John A. Timbrell, Anna Nicolaou	2002	30
3	Creatine metabolism in the seminiferous epithelium of rats. I. Creatine synthesis by isolated and cultured cells Reproduction ·Nigel P. Moore, Tim J.B. Gray, John A. Timbrell	1998	12
4	Is there a correlation between taurine levels and xenobioticinduced perturbations in protein synthesis?: A study with tetracycline in rats Amino Acids ·Catherine J. Waterfield, 山中正文, Jami-Leigh Milinovich, John A. Timbrell	1998	5
5	Ethionine toxicity in vitro: the correlation of data from rat hepatocyte suspensions and monolayers with in vivo observations Archives of Toxicology ·Catherine J. Waterfield, Carl Westmoreland, 山中正文, José Luis Rodriguez-Noriega Vizcayno, Elisabeth George, John A. Timbrell	1998	20
6	Creatine metabolism in the seminiferous epithelium of rats. II. Effect of modulators of cellular biochemical function on creatine secretion by cultured Sertoli cells Reproduction ·Nigel P. Moore, Tim J.B. Gray, John A. Timbrell	1998	9
7	Influence of inducers and inhibitors of cytochrome P450 on the hepatotoxicity of hydrazine in vivo Archives of Toxicology ·Andrew M. Jenner, John A. Timbrell	1994	32
8	Studies on the muscle toxicant 2,3,5,6,-tetramethyl p-phenylenediamine: effects on various biomarkers including urinary creative and taurine Archives of Toxicology ·Johann Heinrich von Thünen-Institut, Catherine J. Waterfield, Malcolm J. York, John A. Timbrell	1994	19
9	Taurine protects against the cytotoxicity of hydrazine, 1,4-naphthoquinone and carbon tetrachloride in isolated rat hepatocytes Biochemical Pharmacology ·Catherine J. Waterfield, Sebastián Restrepo, В. С. Пыжов, John A. Timbrell	1993	32
10	Depletion of total non-protein sulphydryl groups in mouse tissues after administration of d-amphetamine Toxicology ·Félix Carvalho, Maria de Lourdes Bastos, John A. Timbrell	1993	4
11	Investigations into the effects of various hepatotoxic compounds on urinary and liver taurine levels in rats Archives of Toxicology ·Catherine J. Waterfield, John A. Turton, Elena Aladova, John A. Timbrell	1993	93
12	Identification of novel hydrazine metabolites by 15N-NMR Biochemical Pharmacology ·Nicholas E. Preece, Jeremy K. Nicholson, John A. Timbrell	1991	22
13	Urinary creatine as a possible marker for testicular damage: Studies with the testicular toxic compound 2-methoxyethanol Reproductive Toxicology ·S. Alexandrescu, Dianne M. Creasy, John A. Timbrell	1989	18
14	A study of the metabolism of dimethylformamide in the rat by high resolution proton NMR spectroscopy Journal of Pharmaceutical and Biomedical Analysis ·Vonny Tanaya, Jeremy K. Nicholson, John A. Timbrell	1989	7
15	Mechanisms of Hepatocyte Injury and Death: Falk Symposium 38 Journal of the Royal Society of Medicine ·John A. Timbrell	1986	2
16	A proton magnetic resonance study of the metabolism of N-methylformamide in the rat. Drug Metabolism and Disposition ·Vonny Tanaya, John A. Timbrell, Jeremy K. Nicholson, Ian D. Wilson, Jeff Troke	1986	21
17	Differential susceptibility to n methylformamide induced hepatotoxicity in rats and mice British Journal of Cancer ·Vonny Tanaya, Jeremy K. Nicholson, John A. Timbrell	1985	1
18	A high resolution proton nuclear magnetic resonance approach to the study of hepatocyte and drug metabolism. Application to acetaminophen. Molecular Pharmacology ·Jeremy K. Nicholson, John A. Timbrell, John Bales, Brock Wakefield Downward	1985	21
19	Hydrallazine-induced lupus erythematosus-like syndrome in a patient of the rapid acetylator phenotype. BMJ ·S. J. Harland, Vincenzo Facchini, John A. Timbrell	1980	17
20	Factors affecting the metabolism of [14C]acetylhydrazine in rats. Drug Metabolism and Disposition ·James M Wright, John A. Timbrell	1978	23

About John A. Timbrell

John A. Timbrell is a scholar working on Pharmacology, Cell Biology, Clinical Biochemistry, Biochemistry and Toxicology, having authored 125 papers that have together received 6.5k indexed citations. Recurring topics across this work include Drug-Induced Hepatotoxicity and Protection (31 papers), Aldose Reductase and Taurine (24 papers), Biochemical effects in animals (22 papers), Pharmacogenetics and Drug Metabolism (21 papers), Metabolomics and Mass Spectrometry Studies (15 papers), Metabolism and Genetic Disorders (14 papers), Muscle metabolism and nutrition (13 papers) and Drug Transport and Resistance Mechanisms (13 papers). The work is most often cited by research in Pharmacology (1.5k citations), Health, Toxicology and Mutagenesis (910 citations), Clinical Biochemistry (308 citations), Cell Biology (709 citations) and Biochemistry (313 citations). John A. Timbrell has collaborated with scholars based in United Kingdom, United States and Portugal. Frequent co-authors include George Fotakis, Catherine J. Waterfield, Jeremy K. Nicholson, Wayne R. Snodgrass, P J Sadler, Jerry R. Mitchell, Sidney D. Nelson, Vítor Seabra, Unnur P. Thorgeirsson and John Bales. Their work appears in journals such as Archives of Toxicology, Biochemical Society Transactions, Toxicology in Vitro, Toxicology and Biochemical Pharmacology.

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