Jeremy K. Nicholson

105.0k total citations · 35 hit papers
776 papers, 76.1k citations indexed

About

Jeremy K. Nicholson is a scholar working on Molecular Biology, Spectroscopy and Physiology. According to data from OpenAlex, Jeremy K. Nicholson has authored 776 papers receiving a total of 76.1k indexed citations (citations by other indexed papers that have themselves been cited), including 530 papers in Molecular Biology, 218 papers in Spectroscopy and 120 papers in Physiology. Recurrent topics in Jeremy K. Nicholson's work include Metabolomics and Mass Spectrometry Studies (436 papers), Analytical Chemistry and Chromatography (135 papers) and Diet and metabolism studies (95 papers). Jeremy K. Nicholson is often cited by papers focused on Metabolomics and Mass Spectrometry Studies (436 papers), Analytical Chemistry and Chromatography (135 papers) and Diet and metabolism studies (95 papers). Jeremy K. Nicholson collaborates with scholars based in United Kingdom, United States and Australia. Jeremy K. Nicholson's co-authors include Elaine Holmes, John C. Lindon, Ian D. Wilson, James Kinross, Olivier Cloarec, Marc‐Emmanuel Dumas, Timothy M. D. Ebbels, Wei Jia, Hector C. Keun and Sven Pettersson and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

Jeremy K. Nicholson

767 papers receiving 74.3k citations

Hit Papers

Host-Gut Microbiota Metabolic I... 1989 2026 2001 2013 2012 1999 2007 2002 2008 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Host-Gut Microbiota Metabolic Interactions
    2012 3.5k citations Jeremy K. Nicholson, Elaine Holmes et al. Science profile →
  2. 'Metabonomics': understanding the metabolic responses of living systems to pathophysiological stimuli via multivariate statistical analysis of biological NMR spectroscopic data
    1999 3.1k citations Jeremy K. Nicholson, John C. Lindon et al. profile →
  3. Metabolic profiling, metabolomic and metabonomic procedures for NMR spectroscopy of urine, plasma, serum and tissue extracts
    2007 1.6k citations Elaine Holmes, John C. Lindon et al. Nature Protocols profile →
  4. Metabonomics: a platform for studying drug toxicity and gene function
    2002 1.5k citations Jeremy K. Nicholson, John C. Lindon et al. profile →
  5. Metabonomics
    2008 1.5k citations Jeremy K. Nicholson, John C. Lindon profile →
  6. OPLS discriminant analysis: combining the strengths of PLS‐DA and SIMCA classification
    2006 1.2k citations Olivier Cloarec, Jeremy K. Nicholson et al. profile →
  7. Impact of the gut microbiota on inflammation, obesity, and metabolic disease
    2016 1.1k citations Claire L. Boulangé, Ana Luísa Neves et al. profile →
  8. Global metabolic profiling of animal and human tissues via UPLC-MS
    2012 1.0k citations Elizabeth J. Want, Perrine Masson et al. Nature Protocols profile →
  9. 750 MHz 1H and 1H-13C NMR Spectroscopy of Human Blood Plasma
    1995 893 citations Jeremy K. Nicholson, Manfred Spraul et al. Analytical Chemistry profile →
  10. Global metabolic profiling procedures for urine using UPLC–MS
    2010 890 citations Elizabeth J. Want, Ian D. Wilson et al. Nature Protocols profile →
  11. Understanding 'Global' Systems Biology: Metabonomics and the Continuum of Metabolism
    2003 877 citations Jeremy K. Nicholson, Ian D. Wilson profile →
  12. Metabolic profiling reveals a contribution of gut microbiota to fatty liver phenotype in insulin-resistant mice
    2006 847 citations Marc‐Emmanuel Dumas, Richard H. Barton et al. Proceedings of the National Academy of Sciences profile →
  13. Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor
    2013 826 citations Michelle I. Smith, Tanya Yatsunenko et al. Science profile →
  14. Human metabolic phenotype diversity and its association with diet and blood pressure
    2008 813 citations Elaine Holmes, Ruey Leng Loo et al. profile →
  15. Rapid and noninvasive diagnosis of the presence and severity of coronary heart disease using 1H-NMR-based metabonomics
    2002 811 citations Elaine Holmes, Jeremy K. Nicholson et al. profile →
  16. Symbiotic Bacterial Metabolites Regulate Gastrointestinal Barrier Function via the Xenobiotic Sensor PXR and Toll-like Receptor 4
    2014 781 citations Jeremy K. Nicholson, Marc‐Emmanuel Dumas et al. profile →
  17. Gut microorganisms, mammalian metabolism and personalized health care
    2005 705 citations Jeremy K. Nicholson, Elaine Holmes et al. profile →
  18. Statistical Total Correlation Spectroscopy:  An Exploratory Approach for Latent Biomarker Identification from Metabolic 1H NMR Data Sets
    2005 701 citations Olivier Cloarec, Marc‐Emmanuel Dumas et al. Analytical Chemistry profile →
  19. Gut microbiota modulation of chemotherapy efficacy and toxicity
    2017 691 citations Ian D. Wilson, Julian R. Marchesi et al. profile →
  20. Metabolic Phenotyping in Health and Disease
    2008 635 citations Elaine Holmes, Jeremy K. Nicholson et al. profile →
  21. Pharmaco-metabonomic phenotyping and personalized drug treatment
    2006 621 citations T. Andrew Clayton, John C. Lindon et al. profile →
  22. Systemic gut microbial modulation of bile acid metabolism in host tissue compartments
    2010 579 citations Jonathan R. Swann, Elizabeth J. Want et al. Proceedings of the National Academy of Sciences profile →
  23. Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism
    2009 565 citations T. Andrew Clayton, David Baker et al. Proceedings of the National Academy of Sciences profile →
  24. High resolution proton magnetic resonance spectroscopy of biological fluids
    1989 512 citations Jeremy K. Nicholson, Ian D. Wilson profile →
  25. Evaluation of the Orthogonal Projection on Latent Structure Model Limitations Caused by Chemical Shift Variability and Improved Visualization of Biomarker Changes in 1H NMR Spectroscopic Metabonomic Studies
    2004 502 citations Olivier Cloarec, Marc‐Emmanuel Dumas et al. Analytical Chemistry profile →
  26. Gut microbiome-host interactions in health and disease
    2011 497 citations Ara Darzi, Jeremy K. Nicholson et al. profile →
  27. Improved WATERGATE Pulse Sequences for Solvent Suppression in NMR Spectroscopy
    1998 459 citations Jeremy K. Nicholson, John C. Lindon et al. profile →
  28. Gut microbiome interactions with drug metabolism, efficacy, and toxicity
    2016 454 citations Ian D. Wilson, Jeremy K. Nicholson profile →
  29. Preparing for Precision Medicine
    2012 443 citations Jeremy K. Nicholson, Ara Darzi et al. profile →
  30. Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry
    2013 438 citations Laura J. Muirhead, Kirill Veselkov et al. Science Translational Medicine profile →
  31. Microbiome–host systems interactions: protective effects of propionate upon the blood–brain barrier
    2018 423 citations Lesley Hoyles, Jeremy K. Nicholson et al. profile →
  32. The gut microbiota influences skeletal muscle mass and function in mice
    2019 392 citations Shawon Lahiri, Hyejin Kim et al. Science Translational Medicine profile →
  33. Precision High-Throughput Proton NMR Spectroscopy of Human Urine, Serum, and Plasma for Large-Scale Metabolic Phenotyping
    2014 357 citations Hartmut Schäfer, Manfred Spraul et al. Analytical Chemistry profile →
  34. Cervical intraepithelial neoplasia disease progression is associated with increased vaginal microbiome diversity
    2015 340 citations David A. MacIntyre, Ann Smith et al. profile →
  35. The interaction between vaginal microbiota, cervical length, and vaginal progesterone treatment for preterm birth risk
    2017 272 citations Lindsay Kindinger, Phillip R. Bennett et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Jeremy K. Nicholson United Kingdom 130 54.2k 12.9k 12.4k 7.4k 6.4k 776 76.1k
Elaine Holmes United Kingdom 115 40.8k 0.8× 10.9k 0.8× 7.1k 0.6× 6.6k 0.9× 4.5k 0.7× 546 56.8k
David S. Wishart Canada 112 48.3k 0.9× 6.1k 0.5× 7.4k 0.6× 4.2k 0.6× 3.9k 0.6× 553 75.7k
John C. Lindon United Kingdom 90 26.0k 0.5× 4.6k 0.4× 7.4k 0.6× 3.3k 0.4× 3.7k 0.6× 444 35.5k
Barry Halliwell United Kingdom 176 45.3k 0.8× 20.5k 1.6× 2.3k 0.2× 4.3k 0.6× 3.1k 0.5× 736 138.6k
A. Farr United States 7 143.2k 2.6× 30.9k 2.4× 6.7k 0.5× 11.6k 1.6× 10.8k 1.7× 7 295.7k
Matthias Mann Germany 214 150.8k 2.8× 12.2k 0.9× 62.2k 5.0× 11.4k 1.5× 8.1k 1.3× 845 215.4k
Ian D. Wilson United Kingdom 72 19.3k 0.4× 2.9k 0.2× 7.7k 0.6× 1.9k 0.3× 3.9k 0.6× 463 30.0k
Herman J. C. Berendsen Netherlands 67 60.3k 1.1× 3.4k 0.3× 10.2k 0.8× 2.0k 0.3× 13.3k 2.1× 164 112.9k
Berk Hess Sweden 42 45.1k 0.8× 3.3k 0.3× 6.2k 0.5× 1.7k 0.2× 9.2k 1.4× 119 83.5k
Oliver Fiehn United States 102 30.6k 0.6× 3.8k 0.3× 9.1k 0.7× 2.1k 0.3× 4.5k 0.7× 504 45.0k

Countries citing papers authored by Jeremy K. Nicholson

Since Specialization
Citations

This map shows the geographic impact of Jeremy K. Nicholson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeremy K. Nicholson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeremy K. Nicholson more than expected).

Fields of papers citing papers by Jeremy K. Nicholson

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeremy K. Nicholson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeremy K. Nicholson. The network helps show where Jeremy K. Nicholson may publish in the future.

Co-authorship network of co-authors of Jeremy K. Nicholson

This figure shows the co-authorship network connecting the top 25 collaborators of Jeremy K. Nicholson. A scholar is included among the top collaborators of Jeremy K. Nicholson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeremy K. Nicholson. Jeremy K. Nicholson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Hicks, Doris, Lucy Barrett, Silvia Lee, et al.. (2025). Evaluation of tissue-specific extraction protocols for comprehensive lipid profiling. Analytica Chimica Acta. 1347. 343791–343791. 1 indexed citations
2.
3.
Serrano-Contreras, José Iván, John C. Lindon, Gary Frost, et al.. (2023). Implementation of pure shift 1H NMR in metabolic phenotyping for structural information recovery of biofluid metabolites with complex spin systems. NMR in Biomedicine. 37(3). e5060–e5060. 3 indexed citations
4.
Holmes, Elaine, Jeremy K. Nicholson, Mark W. Fear, et al.. (2023). Plasma lipidomics reveal systemic changes persistent throughout early life following a childhood burn injury. Burns & Trauma. 11. tkad044–tkad044. 2 indexed citations
5.
Nitschke, Philipp, Samantha Lodge, Torben Kimhofer, et al.. (2022). J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum. Analytical Chemistry. 94(2). 1333–1341. 17 indexed citations
6.
Kimhofer, Torben, Samantha Lodge, Luke Whiley, et al.. (2021). Correction to “Integrative Modeling of Quantitative Plasma Lipoprotein, Metabolic, and Amino Acid Data Reveals a Multiorgan Pathological Signature of SARS-CoV-2 Infection”. Journal of Proteome Research. 20(6). 3400–3400. 1 indexed citations
7.
Lahiri, Shawon, Hyejin Kim, Isabel García‐Pérez, et al.. (2019). The gut microbiota influences skeletal muscle mass and function in mice. Science Translational Medicine. 11(502). 392 indexed citations breakdown →
8.
Brown, Richard G., Julian R. Marchesi, Yun Sok Lee, et al.. (2018). Vaginal dysbiosis increases risk of preterm fetal membrane rupture, neonatal sepsis and is exacerbated by erythromycin. BMC Medicine. 16(1). 9–9. 193 indexed citations
9.
Dumas, Marc‐Emmanuel, Alice Rothwell, Lesley Hoyles, et al.. (2017). Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance. Cell Reports. 20(1). 136–148. 75 indexed citations
10.
Rodriguez‐Martinez, Andrea, Rafael Ayala, Joram M. Posma, et al.. (2016). MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways. Bioinformatics. 33(5). 773–775. 16 indexed citations
11.
Guenther, Sabine, Laura J. Muirhead, Abigail V.M. Speller, et al.. (2015). Spatially Resolved Metabolic Phenotyping of Breast Cancer by Desorption Electrospray Ionization Mass Spectrometry. Cancer Research. 75(9). 1828–1837. 129 indexed citations
12.
Smith, Michelle I., Tanya Yatsunenko, Mark Manary, et al.. (2013). Gut Microbiomes of Malawian Twin Pairs Discordant for Kwashiorkor. Science. 339(6119). 548–554. 826 indexed citations breakdown →
13.
Want, Elizabeth J., Perrine Masson, Filippos Michopoulos, et al.. (2012). Global metabolic profiling of animal and human tissues via UPLC-MS. Nature Protocols. 8(1). 17–32. 1037 indexed citations breakdown →
14.
Claus, Sandrine P., Sandrine Ellero‐Simatos, Bernard Berger, et al.. (2011). Colonization-Induced Host-Gut Microbial Metabolic Interaction. mBio. 2(2). e00271–10. 336 indexed citations
15.
Swann, Jonathan R., Elizabeth J. Want, Florian Geier, et al.. (2010). Systemic gut microbial modulation of bile acid metabolism in host tissue compartments. Proceedings of the National Academy of Sciences. 108(supplement_1). 4523–4530. 579 indexed citations breakdown →
16.
Clayton, T. Andrew, David Baker, John C. Lindon, Jeremy R. Everett, & Jeremy K. Nicholson. (2009). Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences. 106(34). 14728–14733. 565 indexed citations breakdown →
17.
Wang, Yulan, Jürg Utzinger, Jasmina Saric, et al.. (2008). Global metabolic responses of mice to Trypanosoma brucei brucei infection. Proceedings of the National Academy of Sciences. 105(16). 6127–6132. 102 indexed citations
18.
Wang, Yulan, Elaine Holmes, Jeremy K. Nicholson, et al.. (2004). Metabonomic investigations in mice infected with Schistosoma mansoni : An approach for biomarker identification. Proceedings of the National Academy of Sciences. 101(34). 12676–12681. 229 indexed citations
19.
20.
Preece, Nicholas E., Jeremy K. Nicholson, & John A. Timbrell. (1991). Identification of novel hydrazine metabolites by 15N-NMR. Biochemical Pharmacology. 41(9). 1319–1324. 22 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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