Joelle Le

2.5k citations

16 papers · 1.8k indexed · 1 hit paper · h-index 13

Impact in

Filtration and Separation top 2%
Computational Theory and Mathematics top 1%
- Computational Drug Discovery Methods

Papers in

Filtration and Separation 2
- Chemical and Physical Properties in Aqueous Solutions 2
Immunology and Allergy 5
- Cell Adhesion Molecules Research 5

Co-authors: Michael H. Abraham Brad Sherborne Anne Hersey Yuan H. Zhao Gordon Beck Ian Cooper Chris Luscombe William E. Acree
Journals: Journal of Medicinal Chemistry (3 papers)European Journal of Medicinal Chemistry (2 papers)Journal of Pharmaceutical Sciences (2 papers)Chemosphere (1 paper)Pharmaceutical Research (1 paper)
Partner nations: United Kingdom United States Ireland

In The Last Decade

Joelle Le

16 papers receiving 1.7k citations

Hit Papers

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Rate-Limited Steps of Human Oral Absorption and QSAR Studies 2002 · 621 citations

Peers

Countries citing papers authored by Joelle Le

Since Specialization

Citations

This map shows the geographic impact of Joelle Le's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joelle Le with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joelle Le more than expected).

Fields of papers citing papers by Joelle Le

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joelle Le. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joelle Le. The network helps show where Joelle Le may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Joelle Le, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Joelle Le Line = papers co-authored together Joelle Le links everyone, so they are left out of the graph.

All Works

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16 of 16 papers shown

#	Work
1	Profile of a Highly Selective Quaternized Pyrrolidine Betaine α_vβ₆ Integrin Inhibitor—(3S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((1S and 1R,3R)-1-methyl-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-ium-1-yl)butanoate Synthesized by Stereoselective Methylation Journal of Medicinal Chemistry ·何崇荣, Selda BAYBO, Daniel Barker, Panayiotis A. Procopiou, Ana Paula Costa, John W. Barrett, Joelle Le, Sean M. Lynn, Péter Pogány, Cassie Pratley, John M. Pritchard, James A. Roper, James E. Rowedder, Robert J. Slack, Giovanni Vitulli, Simon J. F. Macdonald, William J. Kerr	2019	6
2	Discovery of an Orally Bioavailable Pan αv Integrin Inhibitor for Idiopathic Pulmonary Fibrosis Journal of Medicinal Chemistry ·Niall A. Anderson, Sébastien Campos, Nurul Afiqah Nordin, Royston C. B. Copley, В. Г. Привалова, Stephen A. Harrison, Joelle Le, Katarzyna Ray, Harvey Friedrich, John M. Pritchard, James E. Rowedder, Claire Smith, P. van Arkel, Giovanni Vitulli, Simon J. F. Macdonald	2019	8
3	Discovery of (S)-3-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenyl)-4-((R)-3-(2-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)ethyl)pyrrolidin-1-yl)butanoic Acid, a Nonpeptidic α_vβ₆ Integrin Inhibitor for the Inhaled Treatment of Idiopathic Pulmonary Fibrosis Journal of Medicinal Chemistry ·Panayiotis A. Procopiou, Niall A. Anderson, John W. Barrett, 何崇荣, 尾山竹滋, Brendan J. Fallon, Ashley P. Hancock, Joelle Le, Paul Mugisha, Richard P. Marshall, Katherine Howlett, John M. Pritchard, James E. Rowedder, Sole Molander, Robert J. Slack, Steven L. Sollis, Colin J. Suckling, J. E. Lim, Giovanni Vitulli, Simon J. F. Macdonald	2018	31
4	From PIM1 to PI3Kδ via GSK3β: Target Hopping through the Kinome ACS Medicinal Chemistry Letters ·F. Govaerts, B.D. Bax, Mónica Dalila Delgadillo Salgado, Fatima Elkabti, Amar Syaiful, Paul Faulder, Joelle Le, Daniel A. Thomas, Yoshiaki Washio, G. Pantziou	2017	14
5	Ein Instrumentarium von αv‐RGD‐Integrin‐Inhibitoren: Wirkstoffsuche, Herausforderungen und Möglichkeiten Angewandte Chemie ·Richard J. D. Hatley, Simon J. F. Macdonald, Robert J. Slack, Joelle Le, Steven B. Ludbrook, Pauline T. Lukey	2017	12
6	An αv‐RGD Integrin Inhibitor Toolbox: Drug Discovery Insight, Challenges and Opportunities Angewandte Chemie International Edition ·Richard J. D. Hatley, Simon J. F. Macdonald, Robert J. Slack, Joelle Le, Steven B. Ludbrook, Pauline T. Lukey	2017	97
7	Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis Bioorganic & Medicinal Chemistry Letters ·Funda Kartoz, Athip Boonsiriwit, Grégory Bar, 弘子杉森, Paul Edwards, Reginald Brys, M.G. Chambers, Wolfgang Schmidt, Angus M. MacLeod, Emilly Marinho Martins, 静男古謝, Véronique Birault, Joelle Le, S. K. Goyal, María Alejandra Ardila Rosas, Kevin M. Nash, Nicholas Haltmeyer	2012	12
8	Bringing Kinases Into Focus: Efficient Drug Design Through the Use of Chemogenomic Toolkits Current Medicinal Chemistry ·Véronique Birault, C.J. Harris, Joelle Le, 梁宗林 Liang Zonglin, Charles Gotlieb, Adrian P. Stevens	2006	12
9	Evaluation of rat intestinal absorption data and correlation with human intestinal absorption European Journal of Medicinal Chemistry ·Yuan H. Zhao, Michael H. Abraham, Joelle Le, Anne Hersey, Chris Luscombe, Gordon Beck, Brad Sherborne, Ian Cooper	2003	71
10	On the mechanism of human intestinal absorption European Journal of Medicinal Chemistry ·Michael H. Abraham, Yuan H. Zhao, Joelle Le, Anne Hersey, Christopher N. Luscombe, Derek P. Reynolds, Gordon Beck, Brad Sherborne, Ian Cooper	2002	67
11	Rate-Limited Steps of Human Oral Absorption and QSAR Studies Pharmaceutical Research ·Yuan H. Zhao, Michael H. Abraham, Joelle Le, Anne Hersey, Chris Luscombe, Gordon Beck, Brad Sherborne, Ian Cooper Hit paper breakdown →	2002	621
12	The solubility of gases and vapours in dry octan-1-ol at 298 K Chemosphere ·Michael H. Abraham, Joelle Le, William E. Acree, Peter W. Carr, Andrew J. Dallas	2001	64
13	Evaluation of human intestinal absorption data and subsequent derivation of a quantitative structure–activity relationship (QSAR) with the Abraham descriptors Journal of Pharmaceutical Sciences ·Yuan H. Zhao, Joelle Le, Michael H. Abraham, Anne Hersey, Peter Eddershaw, Chris Luscombe, Alan A. Block, Gordon Beck, Brad Sherborne, Ian Cooper, James A. Platts	2001	411
14	The Solvation Properties of the Aliphatic Alcohols Collection of Czechoslovak Chemical Communications ·Michael H. Abraham, Joelle Le, William E. Acree	1999	64
15	Solubility of gases and vapours in propan-1-ol at 298 K Journal of Physical Organic Chemistry ·Michael H. Abraham, Joelle Le, William E. Acree, Peter W. Carr	1999	52
16	The correlation and prediction of the solubility of compounds in water using an amended solvation energy relationship Journal of Pharmaceutical Sciences ·Michael H. Abraham, Joelle Le	1999	243

About Joelle Le

Joelle Le is a scholar working on Filtration and Separation, Immunology and Allergy, Pharmaceutical Science, Spectroscopy and Organic Chemistry, having authored 16 papers that have together received 1.8k indexed citations. Recurring topics across this work include Cell Adhesion Molecules Research (5 papers), Crystallization and Solubility Studies (4 papers), Analytical Chemistry and Chromatography (3 papers), Drug Solubulity and Delivery Systems (3 papers), Chemical Thermodynamics and Molecular Structure (3 papers), Chemical and Physical Properties in Aqueous Solutions (2 papers), Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis (2 papers) and Signaling Pathways in Disease (2 papers). The work is most often cited by research in Filtration and Separation (97 citations), Computational Theory and Mathematics (511 citations), Spectroscopy (486 citations), Pharmaceutical Science (171 citations) and Organic Chemistry (650 citations). Joelle Le has collaborated with scholars based in United Kingdom, United States and Ireland. Frequent co-authors include Michael H. Abraham, Brad Sherborne, Anne Hersey, Yuan H. Zhao, Gordon Beck, Ian Cooper, Chris Luscombe, William E. Acree, James A. Platts and Peter Eddershaw. Their work appears in journals such as Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Journal of Pharmaceutical Sciences, Chemosphere and Pharmaceutical Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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