Reginald Brys

1.6k citations

31 papers · 841 indexed · h-index 13

Impact in

Rheumatology top 10%
- Rheumatoid Arthritis Research and Therapies
Genetics top 10%
- Chronic Lymphocytic Leukemia Research

Papers in ⓘ

Genetics 6
- Myeloproliferative Neoplasms: Diagnosis and Treatment 3
- Chronic Lymphocytic Leukemia Research 2
Rheumatology 6
- Rheumatoid Arthritis Research and Therapies 4

Co-authors: N. Vandeghinste (7 shared papers)L. Lepescheux (5 shared papers)Philippe Clément-Lacroix (5 shared papers)Thierry Christophe (4 shared papers)Christel Menet (4 shared papers)L Nelles (3 shared papers)René Galien (8 shared papers)Ellen M. van der Aar (2 shared papers)
Journals: Journal of Medicinal Chemistry (3 papers)Gastroenterology (3 papers)Blood (2 papers)Journal of Crohn s and Colitis (2 papers)Cancer Research (1 paper)
Partner nations: Belgium Germany Ireland

In The Last Decade

Reginald Brys

28 papers receiving 813 citations

Peers

Countries citing papers authored by Reginald Brys

Since Specialization

Citations

This map shows the geographic impact of Reginald Brys's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Reginald Brys with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Reginald Brys more than expected).

Fields of papers citing papers by Reginald Brys

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Reginald Brys. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Reginald Brys. The network helps show where Reginald Brys may publish in the future.

Co-authors

The 25 scholars most cited alongside Reginald Brys, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Reginald Brys Line = papers co-authored together Reginald Brys links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 31 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Preclinical Characterization of GLPG0634, a Selective Inhibitor of JAK1, for the Treatment of Inflammatory Diseases The Journal of Immunology ·Luc Van Rompaey, René Galien, Ellen M. van der Aar, Philippe Clément-Lacroix, L Nelles, Bart Smets, L. Lepescheux, Thierry Christophe, Katja Conrath, N. Vandeghinste, Béatrice Vayssière, Steve De Vos, Stephen R. Fletcher, Reginald Brys, Gerben van ‘t Klooster, Jean H.M. Feyen, Christel Menet	2013	181
2	Neutralization of IL-17C Reduces Skin Inflammation in Mouse Models of Psoriasis and Atopic Dermatitis Journal of Investigative Dermatology ·N. Vandeghinste, Jürgen Klattig, Catherine Jagerschmidt, Stéphanie Lavazais, Florence Marsais, Jan D. Haas, Marielle Auberval, Felix Lauffer, Tara Moran, Maté Ongenaert, Maarten Van Balen, Sonia Dupont, L. Lepescheux, Teresa García, Stefan Härtle, Kilian Eyerich, Padraic G. Fallon, Reginald Brys, Stefan Steidl	2018	94
3	Triazolopyridines as Selective JAK1 Inhibitors: From Hit Identification to GLPG0634 Journal of Medicinal Chemistry ·Christel Menet, Stephen R. Fletcher, Guy Van Lommen, Raphaël Geney, Javier Blanc, Koen Smits, Nolwenn Jouannigot, Pierre Deprez, Ellen M. van der Aar, Philippe Clément-Lacroix, L. Lepescheux, René Galien, Béatrice Vayssière, L Nelles, Thierry Christophe, Reginald Brys, Muriel Uhring, Fabrice Ciesielski, Luc Van Rompaey	2014	93
4	Adenoviral Vectors Expressing siRNAs for Discovery and Validation of Gene Function Genome Research ·Gert‐Jan Arts, Ellen Langemeijer, Rudi Tissingh, Libin Ma, Heidi Pavliska, Kristina Dokic, Richele Dooijes, Emir Mešić, Remko Clasen, Frits Michiels, Jan van der Schueren, Mark Lambrecht, Sofie Herman, Reginald Brys, Kim Thys, Marcel Hoffmann, Peter Tomme, Helmuth van Es	2003	75
5	The α7 nicotinic acetylcholine receptor on fibroblast‐like synoviocytes and in synovial tissue from rheumatoid arthritis patients: A possible role for a key neurotransmitter in synovial inflammation Arthritis & Rheumatism ·Marjolein A. van Maanen, Susanne P. Stoof, Esmerij P. van der Zanden, Wouter J. de Jonge, Richard A. J. Janssen, David F. Fischer, N. Vandeghinste, Reginald Brys, Margriet J. Vervoordeldonk, Paul P. Tak	2009	66
6	Oct-1 Is Involved in the Transcriptional Repression of the von Willebrand Factor Gene Promoter Blood ·Jean-Luc Schwachtgen, Jacques Remacle, Nathalie Janel, Reginald Brys, Danny Huylebroeck, Dominique Meyer, Danièle Kerbiriou‐Nabias	1998	62
7	A multiparameter approach to monitor disease activity in collagen-induced arthritis Arthritis Research & Therapy ·Sylvie Seeuws, Peggy Jacques, Jens Van Praet, Michael Drennan, Julie Coudenys, Tine Decruy, Ellen Deschepper, L. Lepescheux, Philippe Pujuguet, Line Oste, N. Vandeghinste, Reginald Brys, Gust Verbruggen, Dirk Elewaut	2010	61
8	The Medium-Chain Fatty Acid Receptor GPR84 Mediates Myeloid Cell Infiltration Promoting Steatohepatitis and Fibrosis Journal of Clinical Medicine ·Tobias Puengel, Steve De Vos, Jana Hundertmark, Marlene Kohlhepp, Nurdan Güldiken, Philippe Pujuguet, Marielle Auberval, Florence Marsais, Kenji F. Shoji, Laurent Sanière, Christian Trautwein, Tom Luedde, Pavel Strnad, Reginald Brys, Philippe Clément-Lacroix, Frank Tacke	2020	53
9	Reconstitution of the Human 5-HT1D Receptor-G-Protein Coupling: Evidence for Constitutive Activity and Multiple Receptor Conformations Molecular Pharmacology ·Reginald Brys, Katty Josson, M. Paola Castelli, Mirek Jurzak, Peter Lijnen, W Gommeren, Josée E. Leysen	2000	23
10	Discovery and development of ASK1 inhibitors Progress in medicinal chemistry ·Reginald Brys, Karl R. Gibson, Tanja Poljak, Steven Van der Plas, David Amantini	2020	22
11	IRAK4 inhibition dampens pathogenic processes driving inflammatory skin diseases Science Translational Medicine ·Stéphanie Lavazais, Manja Jargosch, Sonia Dupont, Frédéric Labéguère, Christel Menet, Catherine Jagerschmidt, Frenz Ohm, László Kupcsik, Isabelle Parent, C. Cottereaux, Florence Marsais, Line Oste, An Van de Water, Thierry Christophe, Steve De Vos, Padraic G. Fallon, Felix Lauffer, Philippe Clément-Lacroix, Kilian Eyerich, Reginald Brys	2023	22
12	Discovery of the S1P2 Antagonist GLPG2938 (1-[2-Ethoxy-6-(trifluoromethyl)-4-pyridyl]-3-[[5-methyl-6-[1-methyl-3-(trifluoromethyl)pyrazol-4-yl]pyridazin-3-yl]methyl]urea), a Preclinical Candidate for the Treatment of Idiopathic Pulmonary Fibrosis Journal of Medicinal Chemistry ·Oscar Mammoliti, Adeline Palisse, Caroline Joannesse, Sandy El Bkassiny, Brigitte Allart, Alex Jaunet, Christel Menet, Beatrice Coornaert, Kathleen Sonck, Inge Duys, Philippe Clément-Lacroix, Line Oste, Monica Borgonovi, Emanuelle Wakselman, Thierry Christophe, Nicolas Houvenaghel, Mia Jans, Bertrand Heckmann, Laurent Sanière, Reginald Brys	2021	18
13	Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis Bioorganic & Medicinal Chemistry Letters ·Martin J.I. Andrews, J. Andrew Clase, Grégory Bar, Giovanni Tricarico, Paul Edwards, Reginald Brys, M.G. Chambers, Wolfgang Schmidt, Angus M. MacLeod, Kim L. Hirst, Vivienne Allen, Véronique Birault, Joelle Le, John Harris, A. D. H. Self, Kevin M. Nash, Graham Dixon	2012	12
14	Identical cis -Acting Elements and Related trans -Acting Factors Control Activity of Nonviral Promoter in Schizosaccharomyces pombe and Mammalian Cells DNA and Cell Biology ·Reginald Brys, L Nelles, Els Van Der Schueren, Nathalie Silvestre, Danny Huylebroeck, Jacques Remacle	1998	10
15	Strong reversal of the lung fibrosis disease signature by autotaxin inhibitor GLPG1690 in a mouse model for IPF Maté Ongenaert, Sonia Dupont, Roland Blanqué, Reginald Brys, Ellen van der Aar, Bertrand Heckmann	2016	8
16	Oct-1 Is Involved in the Transcriptional Repression of the von Willebrand Factor Gene Promoter Blood ·Jean-Luc Schwachtgen, Jacques Remacle, Nathalie Janel, Reginald Brys, Danny Huylebroeck, Dominique Meyer, Danièle Kerbiriou‐Nabias	1998	6
17	Discovery of GLPG3667, a Selective ATP Competitive Tyrosine Kinase 2 Inhibitor for the Treatment of Autoimmune Diseases Journal of Medicinal Chemistry ·Oscar Mammoliti, Sébastien L. X. Martina, Pieter Claes, Ghjuvanni Coti, Roland Blanqué, Catherine Jagerschmidt, Kenji F. Shoji, Monica Borgonovi, Steve De Vos, Florence Marsais, Line Oste, Evelyne M. Quinton, Miriam López‐Ramos, David Amantini, Reginald Brys, Juan‐Miguel Jimenez, René Galien, Steven Van der Plas	2024	5
18	Pharmacological profile and efficacy of GLPG1690, a novel ATX inhibitor for COPD treatment Roland Blanqué, Nicolas Desroy, Sonia Dupont, C. Cottereaux, Alain Monjardet, Emanuelle Wakselman, Wendy Laenen, Vince Russell, Ellen van der Aar, Reginald Brys, Bertrand Heckmann	2015	5
19	[Amyloidosis in Crohn's disease]. PubMed ·Reginald Brys, S Ringoir, A. Elewaut, F Barbier	1972	5
20	P072 GLPG0634, the first selective JAK1 inhibitor, shows strong activity in the mouse DSS-colitis model Journal of Crohn s and Colitis ·Didier Merciris, Carole Delachaume, Veerle de Vriendt, Alexandre Boutet, L Perret, M.-C. Ceccotti, Shoko Vos, Alain Monjardet, Reginald Brys, René Galien	2014	5

About Reginald Brys

Reginald Brys is a scholar working on Genetics, Rheumatology, Gastroenterology, Dermatology and Oncology, having authored 31 papers that have together received 841 indexed citations. Recurring topics across this work include Cytokine Signaling Pathways and Interactions (5 papers), Rheumatoid Arthritis Research and Therapies (4 papers), Myeloproliferative Neoplasms: Diagnosis and Treatment (3 papers), Helicobacter pylori-related gastroenterology studies (3 papers), Galectins and Cancer Biology (2 papers), Gastrointestinal motility and disorders (2 papers), Dermatology and Skin Diseases (2 papers) and Chronic Lymphocytic Leukemia Research (2 papers). The work is most often cited by research in Rheumatology (160 citations), Genetics (101 citations), Dermatology (82 citations), Immunology and Allergy (51 citations) and Immunology (176 citations). Reginald Brys has collaborated with scholars based in Belgium, Germany and Ireland. Frequent co-authors include N. Vandeghinste, L. Lepescheux, Philippe Clément-Lacroix, Thierry Christophe, Christel Menet, L Nelles, René Galien, Ellen M. van der Aar, Béatrice Vayssière and Stephen R. Fletcher. Their work appears in journals such as Journal of Medicinal Chemistry, Gastroenterology, Blood, Journal of Crohn s and Colitis and Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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