Je‐Wook Yu

8.7k total citations · 4 hit papers
69 papers, 6.6k citations indexed

About

Je‐Wook Yu is a scholar working on Molecular Biology, Immunology and Neurology. According to data from OpenAlex, Je‐Wook Yu has authored 69 papers receiving a total of 6.6k indexed citations (citations by other indexed papers that have themselves been cited), including 53 papers in Molecular Biology, 36 papers in Immunology and 9 papers in Neurology. Recurrent topics in Je‐Wook Yu's work include Inflammasome and immune disorders (44 papers), interferon and immune responses (18 papers) and Heme Oxygenase-1 and Carbon Monoxide (10 papers). Je‐Wook Yu is often cited by papers focused on Inflammasome and immune disorders (44 papers), interferon and immune responses (18 papers) and Heme Oxygenase-1 and Carbon Monoxide (10 papers). Je‐Wook Yu collaborates with scholars based in South Korea, United States and Japan. Je‐Wook Yu's co-authors include Teresa Fernandes‐Alnemri, Emad S. Alnemri, Pinaki Datta, Jianghong Wu, Inhwa Hwang, Christine A. Juliana, Sangjun Park, Sujeong Hong, Jiang Wu and Eunju Lee and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Je‐Wook Yu

66 papers receiving 6.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA

2009 1.5k citations Teresa Fernandes‐Alnemri, Je‐Wook Yu et al. profile →
The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation

2007 831 citations Teresa Fernandes‐Alnemri, Jiang Wu et al. Cell Death and Differentiation profile →
The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

2010 588 citations Teresa Fernandes‐Alnemri, Je‐Wook Yu et al. Nature Immunology profile →
Anti-inflammatory Compounds Parthenolide and Bay 11-7082 Are Direct Inhibitors of the Inflammasome

2010 512 citations Christine A. Juliana, Teresa Fernandes‐Alnemri et al. profile →

Peers

Je‐Wook Yu

IMMUN

EPIDE

SURGE

NEPHR

Amir S. Yazdi Germany

Pinaki Datta United States

Karen V. Swanson United States

Huanwei Huang China

Venkat Giri Magupalli United States

James E. Vince Australia

Haitao Wen United States

Prajwal Gurung United States

Jianbin Ruan United States

Sanjeev Mariathasan United States

Amir S. Yazdi Germany

Je‐Wook Yu

5.0k ×1.0

2.7k ×0.8

IMMUN

1.4k ×2.1

EPIDE

716 ×1.1

SURGE

448 ×0.9

NEPHR

Citations per year, relative to Je‐Wook Yu Je‐Wook Yu (= 1×) peers Amir S. Yazdi

Countries citing papers authored by Je‐Wook Yu

Since Specialization

Citations

This map shows the geographic impact of Je‐Wook Yu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Je‐Wook Yu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Je‐Wook Yu more than expected).

Fields of papers citing papers by Je‐Wook Yu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Je‐Wook Yu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Je‐Wook Yu. The network helps show where Je‐Wook Yu may publish in the future.

Co-authorship network of co-authors of Je‐Wook Yu

This figure shows the co-authorship network connecting the top 25 collaborators of Je‐Wook Yu. A scholar is included among the top collaborators of Je‐Wook Yu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Je‐Wook Yu. Je‐Wook Yu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Kim, Beom Seok, et al.. (2025). Development of New IL-1R Antagonists with Improved Anti-inflammatory Efficacy. Theranostics. 16(5). 2561–2575.

Lee, Eunju, Jaeho Lee, Inhwa Hwang, et al.. (2025). Microglial NLRP3-gasdermin D activation impairs blood-brain barrier integrity through interleukin-1β-independent neutrophil chemotaxis upon peripheral inflammation in mice. Nature Communications. 16(1). 699–699. 15 indexed citations

Kim, Byeongchan, et al.. (2025). The NLRP3 inflammasome in microglia regulates repetitive behavior by modulating NMDA glutamate receptor functions. Cell Reports. 44(5). 115656–115656. 1 indexed citations

Oh, Soo Jin, et al.. (2024). Varicella zoster virus glycoprotein E facilitates PINK1/Parkin-mediated mitophagy to evade STING and MAVS-mediated antiviral innate immunity. Cell Death and Disease. 15(1). 16–16. 12 indexed citations

Shim, Do-Wan, et al.. (2024). Deficiency of circadian clock gene Bmal1 exacerbates noncanonical inflammasome-mediated pyroptosis and lethality via Rev-erbα-C/EBPβ-SAA1 axis. Experimental & Molecular Medicine. 56(2). 370–382. 11 indexed citations

Hwang, Inhwa, et al.. (2023). Extracellular Acidification Augments NLRP3-Mediated Inflammasome Signaling in Macrophages. Immune Network. 23(3). e23–e23. 13 indexed citations

Lee, Hyojeong, Dong‐Wook Kim, Eunji Cheong, et al.. (2022). Differential Regional Vulnerability of the Brain to Mild Neuroinflammation Induced by Systemic LPS Treatment in Mice. Journal of Inflammation Research. Volume 15. 3053–3063. 13 indexed citations

Ahn, Yuri, Jimyung Seo, Eun Jung Lee, et al.. (2020). ATP-P2X7–Induced Inflammasome Activation Contributes to Melanocyte Death and CD8+ T-Cell Trafficking to the Skin in Vitiligo. Journal of Investigative Dermatology. 140(9). 1794–1804.e4. 38 indexed citations

Kim, Minwoo, Hee Cho, Wooseong Lee, et al.. (2020). Antiviral efficacy of orally delivered neoagarohexaose, a nonconventional TLR4 agonist, against norovirus infection in mice. Biomaterials. 263. 120391–120391. 15 indexed citations

10.

Lee, Hyun Jung, Sujeong Hong, Inhwa Hwang, et al.. (2019). Proteomics-based functional studies reveal that galectin-3 plays a protective role in the pathogenesis of intestinal Behçet’s disease. Scientific Reports. 9(1). 11716–11716. 10 indexed citations

11.

Hong, Sujeong & Je‐Wook Yu. (2018). Prolonged Exposure to Lipopolysaccharide Induces NLRP3-Independent Maturation and Secretion of Interleukin (IL)-1�� in Macrophages. Journal of Microbiology and Biotechnology. 28(1). 115–121. 8 indexed citations

12.

Lee, Jung‐Hwan, et al.. (2016). Immunomodulatory/anti-inflammatory effect of ZOE-based dental materials. Dental Materials. 33(1). e1–e12. 27 indexed citations

13.

Kim, Ji Hong, et al.. (2016). Inflammasome activation by cell volume regulation and inflammation-associated hyponatremia: A vicious cycle. Medical Hypotheses. 93. 117–121. 15 indexed citations

14.

Hwang, Inhwa, et al.. (2015). Histone deacetylase 6 negatively regulates NLRP3 inflammasome activation. Biochemical and Biophysical Research Communications. 467(4). 973–978. 47 indexed citations

15.

Yu, Je‐Wook, et al.. (2010). CIIA Is a Novel Regulator of Detachment-Induced Cell Death. Cancer Research. 70(15). 6352–6358. 5 indexed citations

16.

Fernandes‐Alnemri, Teresa, Je‐Wook Yu, Christine A. Juliana, et al.. (2010). The AIM2 inflammasome is critical for innate immunity to Francisella tularensis. Nature Immunology. 11(5). 385–393. 588 indexed citations breakdown →

17.

Yu, Je‐Wook, et al.. (2010). Differential cytoprotective effect of copper- and iron-containing chlorophyllins against oxidative stress-mediated cell death. Free Radical Research. 44(6). 655–667. 10 indexed citations

18.

Jéru, Isabelle, Philippe Duquesnoy, Teresa Fernandes‐Alnemri, et al.. (2008). Mutations in NALP12 cause hereditary periodic fever syndromes. Proceedings of the National Academy of Sciences. 105(5). 1614–1619. 288 indexed citations

19.

Fernandes‐Alnemri, Teresa, Jiang Wu, Je‐Wook Yu, et al.. (2007). The pyroptosome: a supramolecular assembly of ASC dimers mediating inflammatory cell death via caspase-1 activation. Cell Death and Differentiation. 14(9). 1590–1604. 831 indexed citations breakdown →

20.

Kim, Myung‐Ho, et al.. (2006). Gout of the Hallucal Medial Sesamoid - A Case Report -. Journal of Korean Foot and Ankle Society. 10(1). 96–100. 1 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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