Jean‐Pierre Valentin

6.2k citations

198 papers · 4.2k indexed · 1 hit paper · h-index 39

Impact in

Cardiology and Cardiovascular Medicine top 1%
- Cardiac electrophysiology and arrhythmias
Small Animals top 0.5%
- Animal testing and alternatives

Papers in

Small Animals 32
- Animal testing and alternatives 31
Cardiology and Cardiovascular Medicine 87
- Cardiac electrophysiology and arrhythmias 68
- Heart Failure Treatment and Management 10

Co-authors: Tim Hammond Najah Abi‐Gerges Chris Pollard William S. Redfern Richard Weaver Gareth W. John Lorna Ewart Caryn Lawrence
Journals: Toxicological Sciences (12 papers)British Journal of Pharmacology (10 papers)Journal of Pharmacological and Toxicological Methods (81 papers)Journal of Hypertension (6 papers)American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (6 papers)
Partner nations: United Kingdom United States Belgium

In The Last Decade

Jean‐Pierre Valentin

190 papers receiving 4.0k citations

Hit Papers

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The evolving role of investigative toxicology in the pharmaceutical industry 2023 · 132 citations

Peers

Countries citing papers authored by Jean‐Pierre Valentin

Since Specialization

Citations

This map shows the geographic impact of Jean‐Pierre Valentin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Pierre Valentin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Pierre Valentin more than expected).

Fields of papers citing papers by Jean‐Pierre Valentin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Pierre Valentin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Pierre Valentin. The network helps show where Jean‐Pierre Valentin may publish in the future.

Co-authors

The 25 scholars most cited alongside Jean‐Pierre Valentin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jean‐Pierre Valentin Line = papers co-authored together Jean‐Pierre Valentin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	A comprehensive review of 20 years of progress in nonclinical QT evaluation and proarrhythmic assessment Journal of Pharmacokinetics and Pharmacodynamics ·Eric Delpy, Anne‐Marie Bétat, Annie Delaunois, Christophe Drieu La Rochelle, Eric Martel, Jean‐Pierre Valentin	2025	1
2	Collaborative science in action: A 20 year perspective from the Health and Environmental Sciences Institute (HESI) Cardiac Safety Committee Journal of Pharmacological and Toxicological Methods ·Jennifer Pierson, Brian R. Berridge, Ksenia Blinova, Marjory B. Brooks, Sandy Eldridge, Claire E. O’Brien, Michael K. Pugsley, A. Eric Schultze, Godfrey L. Smith, Norman Stockbridge, Jean‐Pierre Valentin, José Vicente	2024	1
3	Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors Toxicological Sciences ·Helga H.J. Gerets, Annie Delaunois, Á. de Pablo Cárdenas, Reiner Class, Renaud Fleurance, Teresa de Haro, Benoı̂t Laleu, Martin Lowe, Marie‐Luce Rosseels, Jean‐Pierre Valentin	2024	4
4	Deconvoluting and derisking QRS complex widening to improve cardiac safety profile of novel plasmepsin X antimalarials Toxicological Sciences ·Annie Delaunois, Á. de Pablo Cárdenas, Teresa de Haro, Helga H.J. Gerets, Vitalina Gryshkova, Simon Hebeisen, Chloé Korlowski, Benoı̂t Laleu, Martin Lowe, Jean‐Pierre Valentin	2024	2
5	Results from a Joined Prospective Study to Evaluate the Sensitivity of the In Vivo Dog QT Assay in Line with the ICH E14/S7B Q&A Best Practices Clinical Pharmacology & Therapeutics ·Anne‐Marie Bétat, Annie Delaunois, Eric Delpy, Mathilde Loiseau, Anne Maurin, Gwendoline Poizat, Céline Posseme, Ferdinand Weinelt, Christophe Drieu La Rochelle, Eric Martel, Jean‐Pierre Valentin	2024	5
6	Testing the nonclinical Comprehensive In Vitro Proarrhythmia Assay (CiPA) paradigm with an established anti‐seizure medication: Levetiracetam case study Pharmacology Research & Perspectives ·Annie Delaunois, François‐Xavier Mathy, Miranda Cornet, Vitalina Gryshkova, Chloé Korlowski, François Bonfitto, Juliane Koch, Anne‐Françoise Schlit, Simon Hebeisen, Elisa Passini, Blanca Rodríguez, Jean‐Pierre Valentin	2023	3
7	Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation SHILAP Revista de lepidopterología ·Benoit Cox, Patrick Barton, Reiner Class, Hannah Coxhead, Claude Delatour, Eric Gillent, Jamie Henshall, Emre M. Isin, Lloyd King, Jean‐Pierre Valentin	2022	17
8	Response of safety pharmacologists to challenges arising from the rapidly evolving changes in the pharmaceutical industry Journal of Pharmacological and Toxicological Methods ·Alan Bass, Michael K. Pugsley, Frederick Sannajust, Takashi Yoshinaga, Jean‐Pierre Valentin	2019	2
9	An overview of the safety pharmacology society strategic plan Journal of Pharmacological and Toxicological Methods ·Michael K. Pugsley, Simon Authier, John Koerner, William S. Redfern, Carrie Markgraf, Tiffini Brabham, Krystle Correll, M. V. Soloviev, Alfred Botchway, Michael J. Engwall, Martin Traebert, Jean‐Pierre Valentin, Tomas Mow, Andrea Greiter‐Wilke, D.J. Leishman, Hugo M. Vargas	2018	4
10	The Concordance between Nonclinical and Phase I Clinical Cardiovascular Assessment from a Cross-Company Data Sharing Initiative Toxicological Sciences ·Lorna Ewart, Mike Aylott, Mark Deurinck, Mike Engwall, David J. Gallacher, Helena Geys, Philip Jarvis, Haisong Ju, Derek J. Leishman, Louise Leong, Nick McMahon, Andy Mead, Philip H. Milliken, Willi Suter, Ard Teisman, Karel Van Ammel, Hugo M. Vargas, Rob Wallis, Jean‐Pierre Valentin	2014	53
11	An evaluation of the non-invasive faecal pellet assessment method as an early drug discovery screen for gastrointestinal liability Journal of Pharmacological and Toxicological Methods ·Louise Marks, Elizabeth Letitia Beard, Des Cobey, Nick Moore, Victoria Motyer, Jean‐Pierre Valentin, Lorna Ewart	2013	11
12	A public–private consortium advances cardiac safety evaluation: Achievements of the HESI Cardiac Safety Technical Committee Journal of Pharmacological and Toxicological Methods ·Jennifer Pierson, Brian R. Berridge, Marjory B. Brooks, Kevin L. Dreher, John Koerner, A. Eric Schultze, R. Dustan Sarazan, Jean‐Pierre Valentin, Hugo M. Vargas, Syril Pettit	2013	21
13	The role of the anaesthetised guinea-pig in the preclinical cardiac safety evaluation of drug candidate compounds Toxicology and Applied Pharmacology ·Louise Marks, Samantha Borland, Karen Philp, Lorna Ewart, Pierre Lainée, Matthew Skinner, Sarah Kirk, Jean‐Pierre Valentin	2012	23
14	Forward Na+-Ca2+ exchange exaggerates beat-to-beat variability of repolarization duration in a cellular model of long-QT1 syndrome European Heart Journal ·Daniel M. Johnson, C.E. Pollard, Jean‐Pierre Valentin, Hjg Crijns, Najah Abi‐Gerges, Paul G.A. Volders	2009	1
15	IKs restricts excessive beat-to-beat variability of repolarization during beta-adrenergic receptor stimulation Journal of Molecular and Cellular Cardiology ·Daniel M. Johnson, Jordi Heijman, Chris Pollard, Jean‐Pierre Valentin, Harry J.G.M. Crijns, Najah Abi‐Gerges, Paul G.A. Volders	2009	63
16	Drug induced shortening of the QT/QTc interval: An emerging safety issue warranting further modelling and evaluation in drug research and development? Journal of Pharmacological and Toxicological Methods ·Mark Holbrook, Marek Malík, Rashmi R. Shah, Jean‐Pierre Valentin	2008	27
17	Optimisation and validation of a medium-throughput electrophysiology-based hNav1.5 assay using IonWorks™ Journal of Pharmacological and Toxicological Methods ·Alexander R. Harmer, Najah Abi‐Gerges, Alison Easter, A. Woods, Caryn Lawrence, Ben G. Small, Jean‐Pierre Valentin, C.E. Pollard	2007	95
18	Receptors for atrial natriuretic peptide are decreased in the kidney of rats with streptozotocin-induced diabetes mellitus. Journal of Clinical Investigation ·Leonardo A. Sechi, Jean‐Pierre Valentin, Chandi Griffin, E Lee, E. Bartoli, M. H. Humphreys, Morris Schambelan	1995	38
19	Cellular basis for blunted volume expansion natriuresis in experimental nephrotic syndrome. Journal of Clinical Investigation ·Jean‐Pierre Valentin, Changbin Qiu, William P. Muldowney, Wei‐Zhong Ying, David G. Gardner, M. H. Humphreys	1992	71
20	Effect of Different Calcium Antagonists on Transcapillary Fluid Shift American Journal of Hypertension ·Jean‐Pierre Valentin, Jean Ribstein, J.-M. Halimi, A Mimran	1990	11

About Jean‐Pierre Valentin

Jean‐Pierre Valentin is a scholar working on Small Animals, Cardiology and Cardiovascular Medicine, Chemical Health and Safety, Toxicology and Computational Theory and Mathematics, having authored 198 papers that have together received 4.2k indexed citations. Recurring topics across this work include Cardiac electrophysiology and arrhythmias (68 papers), Ion channel regulation and function (38 papers), Animal testing and alternatives (31 papers), Computational Drug Discovery Methods (23 papers), Receptor Mechanisms and Signaling (22 papers), Pharmaceutical studies and practices (17 papers), Nitric Oxide and Endothelin Effects (10 papers) and Heart Failure Treatment and Management (10 papers). The work is most often cited by research in Cardiology and Cardiovascular Medicine (1.9k citations), Small Animals (430 citations), Cellular and Molecular Neuroscience (672 citations), Computational Theory and Mathematics (493 citations) and Molecular Biology (1.8k citations). Jean‐Pierre Valentin has collaborated with scholars based in United Kingdom, United States and Belgium. Frequent co-authors include Tim Hammond, Najah Abi‐Gerges, Chris Pollard, William S. Redfern, Richard Weaver, Gareth W. John, Lorna Ewart, Caryn Lawrence, M. H. Humphreys and C.E. Pollard. Their work appears in journals such as Toxicological Sciences, British Journal of Pharmacology, Journal of Pharmacological and Toxicological Methods, Journal of Hypertension and American Journal of Physiology-Regulatory, Integrative and Comparative Physiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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