Jean E. Schaffer

15.4k total citations · 5 hit papers
108 papers, 12.1k citations indexed

About

Jean E. Schaffer is a scholar working on Molecular Biology, Physiology and Cardiology and Cardiovascular Medicine. According to data from OpenAlex, Jean E. Schaffer has authored 108 papers receiving a total of 12.1k indexed citations (citations by other indexed papers that have themselves been cited), including 70 papers in Molecular Biology, 44 papers in Physiology and 19 papers in Cardiology and Cardiovascular Medicine. Recurrent topics in Jean E. Schaffer's work include Peroxisome Proliferator-Activated Receptors (23 papers), Lysosomal Storage Disorders Research (22 papers) and Adipose Tissue and Metabolism (20 papers). Jean E. Schaffer is often cited by papers focused on Peroxisome Proliferator-Activated Receptors (23 papers), Lysosomal Storage Disorders Research (22 papers) and Adipose Tissue and Metabolism (20 papers). Jean E. Schaffer collaborates with scholars based in United States, Germany and Brazil. Jean E. Schaffer's co-authors include Daniel S. Ory, Laura Listenberger, Harvey F. Lodish, Xianlin Han, Sarah E. Lewis, Sylvaine Cases, Robert V. Farese, Sarah E. Gale, Nica M. Borradaile and Rohini Sidhu and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Jean E. Schaffer

106 papers receiving 11.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Triglyceride accumulation protects against fatty acid-induced lipotoxicity

2003 1.6k citations Laura Listenberger, Xianlin Han et al. Proceedings of the National Academy of Sciences profile →
Lipotoxicity: when tissues overeat

2003 741 citations Jean E. Schaffer Current Opinion in Lipidology profile →
Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein

1994 716 citations Jean E. Schaffer et al. profile →
A novel mouse model of lipotoxic cardiomyopathy

2001 632 citations Jean E. Schaffer et al. Journal of Clinical Investigation profile →
Palmitate-induced Apoptosis Can Occur through a Ceramide-independent Pathway

2001 503 citations Laura Listenberger, Daniel S. Ory et al. Journal of Biological Chemistry profile →

Peers

Countries citing papers authored by Jean E. Schaffer

Since Specialization

Citations

This map shows the geographic impact of Jean E. Schaffer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean E. Schaffer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean E. Schaffer more than expected).

Fields of papers citing papers by Jean E. Schaffer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean E. Schaffer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean E. Schaffer. The network helps show where Jean E. Schaffer may publish in the future.

Co-authorship network of co-authors of Jean E. Schaffer

This figure shows the co-authorship network connecting the top 25 collaborators of Jean E. Schaffer. A scholar is included among the top collaborators of Jean E. Schaffer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean E. Schaffer. Jean E. Schaffer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	A pentasaccharide for monitoring pharmacodynamic response to gene therapy in GM1 gangliosidosis 2023 ·EBioMedicine ·Pamela Kell, Rohini Sidhu, Mingxing Qian, (unknown), Elena‐Raluca Nicoli, Precilla D’Souza, Cynthia J. Tifft, Amanda L. Gross, Heather Gray‐Edwards, Douglas R. Martin, (unknown), Dennis J. Dietzen, Manmilan Singh, Jingqin Luo, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang	8
2	Sustained hyperglycemia specifically targets translation of mRNAs for insulin secretion 2023 ·Journal of Clinical Investigation ·(unknown), Jennifer Hollister‐Lock, (unknown), Hui Pan, Jonathan M. Dreyfuss, Susan Bonner‐Weir, Jean E. Schaffer	4
3	Loss of SNORA73 reprograms cellular metabolism and protects against steatohepatitis 2021 ·Nature Communications ·Arthur C. Sletten, (unknown), (unknown), (unknown), Michaela Schwaiger-Haber, Hideji Fujiwara, Sarah E. Gale, Xuntian Jiang, Rohini Sidhu, (unknown), Shuang Zhao, Gary J. Patti, Daniel S. Ory, Jean E. Schaffer	22
4	Genetic Architecture of Circulating Very-Long-Chain (C24:0 and C22:0) Ceramide Concentrations 2020 ·Journal of Lipid and Atherosclerosis ·Sharon Cresci, (unknown), Qiong Yang, Meredith S. Duncan, Vanessa Xanthakis, Xuntian Jiang, Ramachandran S. Vasan, Jean E. Schaffer, Linda R. Peterson	17
5	Alterations in plasma triglycerides and ceramides: links with cardiac function in humans with type 2 diabetes 2020 ·Journal of Lipid Research ·Linda R. Peterson, Xuntian Jiang, Ling Chen, Anne C. Goldberg, Marsha Farmer, Daniel S. Ory, Jean E. Schaffer	18
6	Application of N-palmitoyl-O-phosphocholineserine for diagnosis and assessment of response to treatment in Niemann-Pick type C disease 2020 ·Molecular Genetics and Metabolism ·Rohini Sidhu, Pamela Kell, Dennis J. Dietzen, Nicole Y. Farhat, An Dang, Forbes D. Porter, Elizabeth Berry‐Kravis, Charles H. Vite, Janine Reunert, Thorsten Marquardt, Roberto Giugliani, Charles Marques Lourenço, Olaf A. Bodamer, Raymond Wang, (unknown), Jean E. Schaffer, Daniel Ory, Xuntian Jiang	22
7	Synthesis and characterization of diazirine alkyne probes for the study of intracellular cholesterol trafficking 2019 ·Journal of Lipid Research ·McKenna Feltes, (unknown), Sarah E. Gale, Kathiresan Krishnan, Laurel Mydock‐McGrane, Douglas F. Covey, Daniel Ory, Jean E. Schaffer	17
8	A HILIC‐MS/MS method for simultaneous quantification of the lysosomal disease markers galactosylsphingosine and glucosylsphingosine in mouse serum 2018 ·Biomedical Chromatography ·Rohini Sidhu, (unknown), Hideji Fujiwara, Mark S. Sands, Jean E. Schaffer, Daniel S. Ory, Xuntian Jiang	16
9	A Murine Niemann-Pick C1 I1061T Knock-In Model Recapitulates the Pathological Features of the Most Prevalent Human Disease Allele 2015 ·Journal of Neuroscience ·(unknown), Brett A. Tortelli, Jessie Zhang, Hideji Fujiwara, Rohini Sidhu, (unknown), Zhouji Chen, Chan Chung, Andrew P. Lieberman, Jakub Sikora, Cristin Davidson, Steven U. Walkley, Nina H. Pipalia, Frederick R. Maxfield, Jean E. Schaffer, Daniel Ory	93
10	Plasma Sphingolipids Associated with Chronic Obstructive Pulmonary Disease Phenotypes 2014 ·American Journal of Respiratory and Critical Care Medicine ·Russell P. Bowler, Sean Jacobson, Charmion Cruickshank‐Quinn, Grant Hughes, (unknown), Daniel S. Ory, Irina Petrache, Jean E. Schaffer, Nichole Reisdorph, Katerina Kechris	125
11	Side Chain Oxygenated Cholesterol Regulates Cellular Cholesterol Homeostasis through Direct Sterol-Membrane Interactions 2008 ·Journal of Biological Chemistry ·Sarah E. Gale, Emily J. Westover, (unknown), Kathiresan Krishnan, (unknown), David E. Scherrer, Xianlin Han, Xiuhong Zhai, Howard L. Brockman, Rhoderick E. Brown, Douglas F. Covey, Jean E. Schaffer, Paul H. Schlesinger, Daniel S. Ory	66
12	Limits of a localized magnetic resonance spectroscopy assay for ex vivo myocardial triacylglycerol 2007 ·Journal of Pharmaceutical and Biomedical Analysis ·Robert O’Connor, Robert J. Gropler, Linda R. Peterson, Jean E. Schaffer, Joseph J. H. Ackerman	2
13	Pregnane X receptor (PXR) activation: A mechanism for neuroprotection in a mouse model of Niemann–Pick C disease 2006 ·Proceedings of the National Academy of Sciences ·S. Joshua Langmade, Sarah E. Gale, Andrey Frolov, Ikuko Mohri, Kinuko Suzuki, Synthia H. Mellon, Steven U. Walkley, Douglas F. Covey, Jean E. Schaffer, Daniel Ory	137
14	A Critical Role for Eukaryotic Elongation Factor 1A-1 in Lipotoxic Cell Death 2005 ·Molecular Biology of the Cell ·Nica M. Borradaile, Kimberly K. Buhman, Laura Listenberger, (unknown), Emiko Morimoto, Daniel S. Ory, Jean E. Schaffer	127
15	Oligomerization of the Murine Fatty Acid Transport Protein 1 2003 ·Journal of Biological Chemistry ·(unknown), Laura Listenberger, (unknown), Sarah E. Lewis, Daniel S. Ory, Jean E. Schaffer	32
16	Lipotoxicity: when tissues overeat breakdown → 2003 ·Current Opinion in Lipidology ·Jean E. Schaffer	741
17	Palmitate-induced Apoptosis Can Occur through a Ceramide-independent Pathway breakdown → 2001 ·Journal of Biological Chemistry ·Laura Listenberger, Daniel S. Ory, Jean E. Schaffer	503
18	Substitution of Alanine for Serine 250 in the Murine Fatty Acid Transport Protein Inhibits Long Chain Fatty Acid Transport 1998 ·Journal of Biological Chemistry ·(unknown), (unknown), Jean E. Schaffer	72
19	Characterization of the Murine Fatty Acid Transport Protein Gene and Its Insulin Response Sequence 1998 ·Journal of Biological Chemistry ·To Y. Hui, Brigitte I. Frohnert, Anne J. Smith, Jean E. Schaffer, David Bernlohr	44
20	Cloning, Sequencing, and Functional Analysis of ori _L , a Herpes Simplex Virus Type 1 Origin of DNA Synthesis 1985 ·Molecular and Cellular Biology ·Sandra K. Weller, (unknown), Jean E. Schaffer, Andrew W. Murray, Allan M. Maxam, Priscilla A. Schaffer	111

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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