James P. O’Connell

3.3k citations

36 papers · 2.6k indexed · h-index 25

Cancer Research top 2%
- Protease and Inhibitor Mechanisms 12
Hematology top 2%
- Blood Coagulation and Thrombosis Mechanisms 8
Immunology and Allergy top 5%
Oncology top 5%
- Peptidase Inhibition and Analysis 7
Molecular Biology top 10%
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 6
Biotechnology
- Enzyme Production and Characterization 5
Biomedical Engineering
- Microfluidic and Capillary Electrophoresis Applications 3
Physiology
- Nitric Oxide and Endothelin Effects 2
Immunology
- Immunotherapy and Immune Responses 2

Co-authors: Andrew Docherty Gillian Murphy Frances Willenbrock William F. Butler Michael J. Heller Eugene Tu Thomas Crabbe Edward L. Sheldon
Cited by: Cancer Research Hematology Immunology and Allergy
Journals: Nature Communications (3 papers)Bioorganic & Medicinal Chemistry Letters (3 papers)Biochemistry (3 papers)
Partner nations: United Kingdom United States Canada

In The Last Decade

James P. O’Connell

35 papers receiving 2.5k citations

Peers

Countries citing papers authored by James P. O’Connell

Since Specialization

Citations

This map shows the geographic impact of James P. O’Connell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James P. O’Connell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James P. O’Connell more than expected).

Fields of papers citing papers by James P. O’Connell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James P. O’Connell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James P. O’Connell. The network helps show where James P. O’Connell may publish in the future.

Co-authorship network

The 25 scholars most cited alongside James P. O’Connell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with James P. O’Connell Line = papers co-authored together James P. O’Connell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Glasgow-Blatchford and Rockall score utility in predicting findings on video capsule endoscopy in patients admitted with overt small bowel bleeding SHILAP Revista de lepidopterología ·GOKUL PRAKASH.M,James P. O’Connell,Edilson Santos de Oliveira Duarte,Sruthy S. S,Pradip Chakravarty,Marysa Georgina Neri Velázquez,Pedro F. Oliveira	2024	0
2	A conformation-selective monoclonal antibody against a small molecule-stabilised signalling-deficient form of TNF Nature Communications ·Daniel Lightwood,G.D. Patel,John Porter,David McMillan,Bruce Carrington,Alison Turner,Anthony Scott-Tucker,Aaron Chaln,Antje Schmidt,David Fox,Alison Maloney,Tom Ceska,Tim Bourne,James P. O’Connell,Alastair D. G. Lawson	2021	22
3	Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF Nature Communications ·David McMillan,C. Martinez-Fleites,John Porter,David Fox,Rachel E. Davis,RJM CRAIK,Tom Ceska,Bruce Carrington,Alastair D. G. Lawson,Tim Bourne,James P. O’Connell	2021	63
4	Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer Nature Communications ·James P. O’Connell,John Porter,Pradipta Rizky Ferdian,Merav Omer‐Itsicovich,Stephen Rapecki,Rachel E. Davis,David McMillan,T.L. Arakaki,Alex B. Burgin,David Fox,Tom Ceska,Fabien Lecomte,Alison Maloney,Meghan Sharkey,Bruce Carrington,Benjamin P. Cossins,Tim Bourne,Alastair D. G. Lawson	2019	81
5	mTOR direct interactions with Rheb-GTPase and raptor: sub-cellular localization using fluorescence lifetime imaging BMC Cell Biology ·Alberto Rodríguez Miralles,Pierre Burgos,Anthony W. Parker,Valentina Iadevaia,Christopher G. Proud,Rodger A. Allen,James P. O’Connell,P. HEGNER,Christopher D. Stubbs,Stanley W. Botchway	2013	55
6	Minimizing Tolerance and Withdrawal to Prolonged Pediatric Sedation: Case Report and Review of the Literature Journal of Intensive Care Medicine ·Donald L Laukkanen,James P. O’Connell,Niniola Olaniyan,Mario A. Inchiosa	2007	26
7	4-Thiophenoxy-N-(3,4,5-Trialkoxyphenyl)Pyrimidine-2-Amines as Potent and Selective Inhibitors of the T-Cell Tyrosine Kinase p56lck Current Medicinal Chemistry ·D. Moffat,Rodger A. Allen,Stephen Rapecki,Peter D. Davis,James P. O’Connell,José Luis Barrigón,M. Soledad Janita-Muñoz,Byron A. Boyce,Maria de Jesus Perry	2004	2
8	4-Pyridin-5-yl-2-(3,4,5-trimethoxyphenylamino)pyrimidines: Potent and selective inhibitors of ZAP 70 Bioorganic & Medicinal Chemistry Letters ·David Moffat,Peter D. Davis,José Luis Barrigón,Jeremy Davis,Daniel Berg,Mark Batchelor,James M. Johnson,James P. O’Connell,Richard Martin,Oliver Tiago Reis Marques,為夫中野,IŞIKDOĞAN Davut	1999	14
9	Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips Nature Biotechnology ·Jing Cheng,Edward L. Sheldon,Lei Wu,A I Socrates,I. Savysyuk,John J. Carrino,Michael J. Heller,James P. O’Connell	1998	253
10	CDP840 Cell Biochemistry and Biophysics ·Maria de Jesus Perry,James P. O’Connell,Christoph Walker,Thomas Crabbe,Chao-jue Huang,Annette Russell,Simon Lumb,Zheng Huang,D. Howat,Rodger A. Allen,Costas Filios,徹夫古倉,T M Daniel,B. Hughes,France Laliberté,G.A. Higgs,Raymond J. Owens	1998	23
11	Isolation of Cultured Cervical Carcinoma Cells Mixed with Peripheral Blood Cells on a Bioelectronic Chip Analytical Chemistry ·Jing Cheng,Edward L. Sheldon,Lei Wu,Michael J. Heller,James P. O’Connell	1998	126
12	Rapid determination of single base mismatch mutations in DNA hybrids by direct electric field control Proceedings of the National Academy of Sciences ·A. Izeki,Eugene Tu,William F. Butler,James P. O’Connell,Michael J. Heller	1997	362
13	Inactivation of tissue inhibitor of metalloproteinase‐1 by peroxynitrite FEBS Letters ·Emma R. Frears,I. I. Shanenkov,David R. Blake,James P. O’Connell,Paul G. Winyard	1996	141
14	An in Vivo Model for Screening Peptidomimetic Inhibitors of Gelatinase A Journal of Pharmaceutical Sciences ·Surinder K. Chander,Pari Antoniw,Nigel R. A. Beeley,Byron A. Boyce,Thomas Crabbe,Andrew Docherty,J. C. Leonard,Barbara Mason,Kenneth Millar,Andrew T. Millican,Richard Morphy,Andrew Mountain,James P. O’Connell,John Porter,N. Willmott	1995	10
15	Reciprocated matrix metalloproteinase activation: A process performed by interstitial collagenase and progelatinase A Biochemistry ·Thomas Crabbe,James P. O’Connell,Bryan John Smith,Andrew Docherty	1994	82
16	Mutation of the Active Site Glutamic Acid of Human Gelatinase A: Effects on Latency, Catalysis, and the Binding of Tissue Inhibitor of Metalloproteinases-1 Biochemistry ·Thomas Crabbe,Stanley Zucker,Mark I. Cockett,Frances Willenbrock,Simon Tickle,James P. O’Connell,Hélène Garneau,Gillian Murphy,Andrew Docherty	1994	59
17	Analysis of the role of the COOH-terminal domain in the activation, proteolytic activity, and tissue inhibitor of metalloproteinase interactions of gelatinase B. Journal of Biological Chemistry ·James P. O’Connell,Frances Willenbrock,Andrew Docherty,Maheshwari Bombale,Gillian Murphy	1994	135
18	Human progelatinase A can be activated by matrilysin FEBS Letters ·Thomas Crabbe,Bryan Ronain Smith,James P. O’Connell,Andrew Docherty	1994	82
19	Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives Bioorganic & Medicinal Chemistry Letters ·John Porter,Nigel R. A. Beeley,Byron A. Boyce,Barbara Mason,Andrew T. Millican,Kenneth Millar,J. C. Leonard,J. Richard Morphy,James P. O’Connell	1994	33
20	The matrix metalloproteinases and their natural inhibitors: prospects for treating degenerative tissue diseases Trends in biotechnology ·Andrew Docherty,James P. O’Connell,Tom Crabbe,Sarojani Angal,Gillian Murphy	1992	168

About James P. O’Connell

James P. O’Connell is a scholar working on Cancer Research, Hematology, Biotechnology, Biophysics and Immunology and Allergy, having authored 36 papers that have together received 2.6k indexed citations. Recurring topics across this work include Protease and Inhibitor Mechanisms (12 papers), Blood Coagulation and Thrombosis Mechanisms (8 papers), Peptidase Inhibition and Analysis (7 papers), Monoclonal and Polyclonal Antibodies Research (6 papers), Enzyme Production and Characterization (5 papers), Microfluidic and Capillary Electrophoresis Applications (3 papers), Nitric Oxide and Endothelin Effects (2 papers) and Immunotherapy and Immune Responses (2 papers). The work is most often cited by research in Cancer Research (1.0k citations), Hematology (417 citations), Immunology and Allergy (188 citations), Oncology (652 citations) and Molecular Biology (1.1k citations). James P. O’Connell has collaborated with scholars based in United Kingdom, United States and Canada. Frequent co-authors include Andrew Docherty, Gillian Murphy, Frances Willenbrock, William F. Butler, Michael J. Heller, Eugene Tu, Thomas Crabbe, Edward L. Sheldon, Lei Wu and Michael J. Heller. Their work appears in journals such as Nature Communications, Bioorganic & Medicinal Chemistry Letters, Biochemistry, FEBS Letters and Biochemical Journal.

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