Thomas Crabbe

2.5k total citations · 1 hit paper
20 papers, 2.1k citations indexed

About

Thomas Crabbe is a scholar working on Cancer Research, Oncology and Hematology. According to data from OpenAlex, Thomas Crabbe has authored 20 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Cancer Research, 12 papers in Oncology and 8 papers in Hematology. Recurrent topics in Thomas Crabbe's work include Protease and Inhibitor Mechanisms (15 papers), Peptidase Inhibition and Analysis (12 papers) and Blood Coagulation and Thrombosis Mechanisms (8 papers). Thomas Crabbe is often cited by papers focused on Protease and Inhibitor Mechanisms (15 papers), Peptidase Inhibition and Analysis (12 papers) and Blood Coagulation and Thrombosis Mechanisms (8 papers). Thomas Crabbe collaborates with scholars based in United Kingdom, Canada and Germany. Thomas Crabbe's co-authors include Gillian Murphy, Andrew Docherty, Susan J. Atkinson, Michael J. Butler, James P. O’Connell, Frances Willenbrock, Georgina S. Butler, Tatsuya Tamura, Horst Will and Marie‐Pia d’Ortho and has published in prestigious journals such as Journal of Biological Chemistry, Biochemistry and Cancer Research.

In The Last Decade

Thomas Crabbe

20 papers receiving 2.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A

1998 510 citations Georgina S. Butler, Michael J. Butler et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Thomas Crabbe United Kingdom	17	1.5k	961	674	669	332	20	2.1k
David C. Gervasi United States	12	1.4k 0.9×	714 0.7×	709 1.1×	421 0.6×	241 0.7×	12	1.8k
Lise Christensen Denmark	15	1.1k 0.7×	574 0.6×	718 1.1×	407 0.6×	377 1.1×	30	1.9k
Morten Johnsen Denmark	23	1.1k 0.7×	688 0.7×	1.2k 1.8×	312 0.5×	368 1.1×	31	2.3k
M Seiki Japan	8	1.1k 0.7×	650 0.7×	646 1.0×	296 0.4×	346 1.0×	9	1.6k
L M Matrisian United States	11	1.7k 1.1×	1.4k 1.4×	1.4k 2.1×	362 0.5×	599 1.8×	12	3.1k
Susan P. Hawkes United States	16	1.1k 0.7×	572 0.6×	623 0.9×	512 0.8×	195 0.6×	29	1.8k
C Wolf France	12	1.2k 0.8×	1.0k 1.1×	870 1.3×	260 0.4×	518 1.6×	12	2.1k
Heather F. Bigg United Kingdom	16	876 0.6×	642 0.7×	518 0.8×	351 0.5×	204 0.6×	22	1.4k
Helene Solberg Denmark	18	930 0.6×	733 0.8×	1.0k 1.5×	474 0.7×	290 0.9×	24	2.4k
Maria Teresa Masucci Italy	15	1.0k 0.7×	779 0.8×	713 1.1×	468 0.7×	310 0.9×	28	2.2k

Countries citing papers authored by Thomas Crabbe

Since Specialization

Citations

This map shows the geographic impact of Thomas Crabbe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas Crabbe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas Crabbe more than expected).

Fields of papers citing papers by Thomas Crabbe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas Crabbe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas Crabbe. The network helps show where Thomas Crabbe may publish in the future.

Co-authorship network of co-authors of Thomas Crabbe

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas Crabbe. A scholar is included among the top collaborators of Thomas Crabbe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas Crabbe. Thomas Crabbe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Veverka, Václav, Thomas Crabbe, Ian M. Bird, et al.. (2007). Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. Oncogene. 27(5). 585–595. 122 indexed citations

Crabbe, Thomas. (2007). Exploring the potential of PI3K inhibitors for inflammation and cancer. Biochemical Society Transactions. 35(2). 253–256. 11 indexed citations

Nisato, Riccardo E., Christian Sirrenberg, Georgina S. Butler, et al.. (2005). Dissecting the Role of Matrix Metalloproteinases (MMP) and Integrin αvβ3 in Angiogenesis In vitro : Absence of Hemopexin C Domain Bioactivity, but Membrane-Type 1-MMP and αvβ3 Are Critical. Cancer Research. 65(20). 9377–9387. 54 indexed citations

Pelt, Jos van, Chris Verslype, Thomas Crabbe, Z. Zaman, & Johan Fevery. (2003). PRIMARY HUMAN HEPATOCYTES ARE PROTECTED AGAINST PROLONGED AND REPEATED EXPOSURE TO ETHANOL BY SILIBININ-DIHEMISUCCINATE. Alcohol and Alcoholism. 38(5). 411–414. 23 indexed citations

Butler, Georgina S., Michael J. Butler, Susan J. Atkinson, et al.. (1998). The TIMP2 Membrane Type 1 Metalloproteinase “Receptor” Regulates the Concentration and Efficient Activation of Progelatinase A. Journal of Biological Chemistry. 273(2). 871–880. 510 indexed citations breakdown →

Perry, Maria de Jesus, James P. O’Connell, Christoph Walker, et al.. (1998). CDP840. Cell Biochemistry and Biophysics. 29(1-2). 113–132. 23 indexed citations

Murphy, Gillian, et al.. (1998). Matrix metalloproteinases and metastatic cancer.. PubMed. 63. 295–313. 108 indexed citations

Gohlke, U., F. Xavier Gomis‐Rüth, Thomas Crabbe, et al.. (1996). The C‐terminal (haemopexin‐like) domain structure of human gelatinase A (MMP2): structural implications for its function. FEBS Letters. 378(2). 126–130. 75 indexed citations

Crabbe, Thomas, A. Neil C. Weir, Michael E. Brown, et al.. (1996). The Secretion of Active Recombinant Human Gastric Lipase bySaccharomyces cerevisiae. Protein Expression and Purification. 7(3). 229–236. 18 indexed citations

10.

Crabbe, Thomas, Sharon M. Kelly, & Nicholas C. Price. (1996). An analysis of the conformational changes that accompany the activation and inhibition of gelatinase A. FEBS Letters. 380(1-2). 53–57. 6 indexed citations

11.

Chander, Surinder K., Pari Antoniw, Nigel R. A. Beeley, et al.. (1995). An in Vivo Model for Screening Peptidomimetic Inhibitors of Gelatinase A. Journal of Pharmaceutical Sciences. 84(4). 404–409. 10 indexed citations

12.

Atkinson, Susan J., Thomas Crabbe, Robin V. Ward, et al.. (1995). Intermolecular Autolytic Cleavage Can Contribute to the Activation of Progelatinase A by Cell Membranes. Journal of Biological Chemistry. 270(51). 30479–30485. 217 indexed citations

13.

Murphy, Gillian & Thomas Crabbe. (1995). [28] Gelatinases A and B. Methods in enzymology on CD-ROM/Methods in enzymology. 248. 470–484. 162 indexed citations

14.

Crabbe, Thomas, James P. O’Connell, Bryan John Smith, & Andrew Docherty. (1994). Reciprocated matrix metalloproteinase activation: A process performed by interstitial collagenase and progelatinase A. Biochemistry. 33(48). 14419–14425. 82 indexed citations

15.

Crabbe, Thomas, Stanley Zucker, Mark I. Cockett, et al.. (1994). Mutation of the Active Site Glutamic Acid of Human Gelatinase A: Effects on Latency, Catalysis, and the Binding of Tissue Inhibitor of Metalloproteinases-1. Biochemistry. 33(21). 6684–6690. 59 indexed citations

16.

Crabbe, Thomas, Bryan Ronain Smith, James P. O’Connell, & Andrew Docherty. (1994). Human progelatinase A can be activated by matrilysin. FEBS Letters. 345(1). 14–16. 82 indexed citations

17.

Murphy, Gillian, Frances Willenbrock, Thomas Crabbe, et al.. (1994). Regulation of Matrix Metalloproteinase Activity^a. Annals of the New York Academy of Sciences. 732(1). 31–41. 183 indexed citations

18.

Willenbrock, Frances, Thomas Crabbe, Patrick M. Slocombe, et al.. (1993). The activity of the tissue inhibitors of metalloproteinases is regulated by C-terminal domain interactions: A kinetic analysis of the inhibition of gelatinase A. Biochemistry. 32(16). 4330–4337. 206 indexed citations

19.

Crabbe, Thomas, Christos V. Ioannou, & Andrew Docherty. (1993). Human progelatinase A can be activated by autolysis at a rate that is concentration‐dependent and enhanced by heparin bound to the C‐terminal domain. European Journal of Biochemistry. 218(2). 431–438. 90 indexed citations

20.

Crabbe, Thomas, Frances Willenbrock, Peter J. Hynds, et al.. (1992). Biochemical characterization of matrilysin. Activation conforms to the stepwise mechanisms proposed for other matrix metalloproteinases. Biochemistry. 31(36). 8500–8507. 75 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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