J L Goldstein

13.8k total citations · 9 hit papers
57 papers, 11.9k citations indexed

About

J L Goldstein is a scholar working on Molecular Biology, Surgery and Cancer Research. According to data from OpenAlex, J L Goldstein has authored 57 papers receiving a total of 11.9k indexed citations (citations by other indexed papers that have themselves been cited), including 35 papers in Molecular Biology, 23 papers in Surgery and 14 papers in Cancer Research. Recurrent topics in J L Goldstein's work include Cholesterol and Lipid Metabolism (18 papers), RNA and protein synthesis mechanisms (15 papers) and Cancer, Lipids, and Metabolism (11 papers). J L Goldstein is often cited by papers focused on Cholesterol and Lipid Metabolism (18 papers), RNA and protein synthesis mechanisms (15 papers) and Cancer, Lipids, and Metabolism (11 papers). J L Goldstein collaborates with scholars based in United States, Poland and Switzerland. J L Goldstein's co-authors include M S Brown, Michael S. Brown, Matthew S. Brown, Jay D. Horton, Robert E. Hammer, Iichiro Shimomura, Hitoshi Shimano, Petri T. Kovanen, Joachim Herz and Robert Kowal and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Investigation.

In The Last Decade

J L Goldstein

56 papers receiving 11.3k citations

Hit Papers

Isoform 1c of sterol regu... 1979 2026 1994 2010 1997 1996 1998 1979 1979 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.
    1997 714 citations Hitoshi Shimano, Jay D. Horton et al. Journal of Clinical Investigation profile →
  2. Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.
    1996 705 citations Hitoshi Shimano, Jay D. Horton et al. Journal of Clinical Investigation profile →
  3. Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.
    1998 596 citations Jay D. Horton, Iichiro Shimomura et al. Journal of Clinical Investigation profile →
  4. Receptor-mediated endocytosis: insights from the lipoprotein receptor system.
    1979 560 citations M S Brown, J L Goldstein Proceedings of the National Academy of Sciences profile →
  5. Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.
    1979 506 citations Petri T. Kovanen, M S Brown et al. Journal of Biological Chemistry profile →
  6. Mevinolin and colestipol stimulate receptor-mediated clearance of low density lipoprotein from plasma in familial hypercholesterolemia heterozygotes.
    1983 456 citations Matthew S. Brown, J L Goldstein et al. Proceedings of the National Academy of Sciences profile →
  7. The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E.
    1980 408 citations E. Windler, Petri T. Kovanen et al. Journal of Biological Chemistry profile →
  8. Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.
    1981 366 citations Petri T. Kovanen, D W Bilheimer et al. Proceedings of the National Academy of Sciences profile →
  9. Active and inactive forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the liver of the rat. Comparison with the rate of cholesterol synthesis in different physiological states.
    1979 273 citations Michael S. Brown, J L Goldstein et al. Journal of Biological Chemistry profile →

Author Peers

Peers are selected by citation overlap in the author's most active subfields. citations · hero ref

Author Last Decade Papers Cites
J L Goldstein 6.3k 5.4k 2.3k 1.9k 1.3k 57 11.9k
John A. Glomset 6.6k 1.0× 4.5k 0.8× 1.9k 0.8× 2.3k 1.2× 1.5k 1.2× 85 13.3k
J L Goldstein 5.1k 0.8× 4.8k 0.9× 2.2k 1.0× 1.8k 0.9× 1.3k 1.0× 60 10.7k
Yves L. Marcel 4.5k 0.7× 4.9k 0.9× 2.1k 0.9× 3.5k 1.8× 833 0.7× 155 10.8k
M S Brown 8.8k 1.4× 6.0k 1.1× 2.7k 1.2× 2.2k 1.1× 3.2k 2.5× 57 16.0k
Linda K. Curtiss 4.8k 0.8× 5.1k 0.9× 1.9k 0.8× 2.8k 1.5× 548 0.4× 190 15.0k
Y K Ho 3.8k 0.6× 4.5k 0.8× 1.9k 0.8× 1.2k 0.6× 1.0k 0.8× 41 9.1k
T L Innerarity 5.1k 0.8× 6.1k 1.1× 3.5k 1.5× 4.5k 2.3× 813 0.6× 84 12.3k
John F. Oram 5.3k 0.9× 7.2k 1.3× 2.0k 0.9× 2.6k 1.4× 702 0.6× 115 11.9k
Trudy M. Forte 3.6k 0.6× 3.8k 0.7× 1.6k 0.7× 3.3k 1.7× 569 0.4× 175 9.5k
Sissel Lund‐Katz 5.1k 0.8× 4.7k 0.9× 1.4k 0.6× 3.1k 1.6× 630 0.5× 147 9.7k

Countries citing papers authored by J L Goldstein

Since Specialization
Citations

This map shows the geographic impact of J L Goldstein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J L Goldstein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J L Goldstein more than expected).

Fields of papers citing papers by J L Goldstein

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J L Goldstein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J L Goldstein. The network helps show where J L Goldstein may publish in the future.

Co-authorship network of co-authors of J L Goldstein

This figure shows the co-authorship network connecting the top 25 collaborators of J L Goldstein. A scholar is included among the top collaborators of J L Goldstein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with J L Goldstein. J L Goldstein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Horton, Jay D., J L Goldstein, & Michael S. Brown. (2002). SREBPs: Transcriptional Mediators of Lipid Homeostasis. Cold Spring Harbor Symposia on Quantitative Biology. 67(0). 491–498. 177 indexed citations
2.
Horton, Jay D., Iichiro Shimomura, Matthew Brown, et al.. (1998). Activation of cholesterol synthesis in preference to fatty acid synthesis in liver and adipose tissue of transgenic mice overproducing sterol regulatory element-binding protein-2.. Journal of Clinical Investigation. 101(11). 2331–2339. 596 indexed citations breakdown →
3.
Shimomura, Iichiro, Yuriy K. Bashmakov, Robert E. Hammer, et al.. (1998). Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N).. Journal of Clinical Investigation. 102(12). 2050–2060. 61 indexed citations
4.
Shimano, Hitoshi, Jay D. Horton, Iichiro Shimomura, et al.. (1997). Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells.. Journal of Clinical Investigation. 99(5). 846–854. 714 indexed citations breakdown →
5.
Shimano, Hitoshi, Iichiro Shimomura, Robert E. Hammer, et al.. (1997). Elevated levels of SREBP-2 and cholesterol synthesis in livers of mice homozygous for a targeted disruption of the SREBP-1 gene.. Journal of Clinical Investigation. 100(8). 2115–2124. 380 indexed citations
6.
Shimano, Hitoshi, Jay D. Horton, Robert E. Hammer, et al.. (1996). Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a.. Journal of Clinical Investigation. 98(7). 1575–1584. 705 indexed citations breakdown →
7.
Weisgraber, Karl H., Robert W. Mahley, Robert Kowal, et al.. (1990). Apolipoprotein C-I modulates the interaction of apolipoprotein E with beta-migrating very low density lipoproteins (beta-VLDL) and inhibits binding of beta-VLDL to low density lipoprotein receptor-related protein.. Journal of Biological Chemistry. 265(36). 22453–22459. 199 indexed citations
8.
Hobbs, Helen H., et al.. (1989). Evidence for a dominant gene that suppresses hypercholesterolemia in a family with defective low density lipoprotein receptors.. Journal of Clinical Investigation. 84(2). 656–664. 119 indexed citations
9.
Osborne, Timothy F., Gregorio Gil, J L Goldstein, & Michael S. Brown. (1988). Operator constitutive mutation of 3-hydroxy-3-methylglutaryl coenzyme A reductase promoter abolishes protein binding to sterol regulatory element.. Journal of Biological Chemistry. 263(7). 3380–3387. 178 indexed citations
10.
Lehrman, Mark A., David W. Russell, J L Goldstein, & Matthew S. Brown. (1986). Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia.. Proceedings of the National Academy of Sciences. 83(11). 3679–3683. 148 indexed citations
11.
Gil, Gregorio, J L Goldstein, Clive A. Slaughter, & Michael S. Brown. (1986). Cytoplasmic 3-hydroxy-3-methylglutaryl coenzyme A synthase from the hamster. I. Isolation and sequencing of a full-length cDNA.. Journal of Biological Chemistry. 261(8). 3710–3716. 103 indexed citations
12.
Huettinger, M, Jo Corbett, Wolfgang J. Schneider, et al.. (1984). Imaging of hepatic low density lipoprotein receptors by radionuclide scintiscanning in vivo.. Proceedings of the National Academy of Sciences. 81(23). 7599–7603. 28 indexed citations
13.
Luskey, K L, J R Faust, Daniel J. Chin, M S Brown, & J L Goldstein. (1983). Amplification of the gene for 3-hydroxy-3-methylglutaryl coenzyme A reductase, but not for the 53-kDa protein, in UT-1 cells.. Journal of Biological Chemistry. 258(13). 8462–8469. 174 indexed citations
14.
Beisiegel†, Ulrike, Wolfgang J. Schneider, J L Goldstein, R G Anderson, & Matthew S. Brown. (1981). Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemia.. Journal of Biological Chemistry. 256(22). 11923–11931. 325 indexed citations
15.
Kovanen, Petri T., M S Brown, S K Basu, D W Bilheimer, & J L Goldstein. (1981). Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits.. Proceedings of the National Academy of Sciences. 78(3). 1396–1400. 291 indexed citations
16.
Windler, E., Petri T. Kovanen, Y S Chao, et al.. (1980). The estradiol-stimulated lipoprotein receptor of rat liver. A binding site that membrane mediates the uptake of rat lipoproteins containing apoproteins B and E.. Journal of Biological Chemistry. 255(21). 10464–10471. 408 indexed citations breakdown →
17.
Kovanen, Petri T., M S Brown, & J L Goldstein. (1979). Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.. Journal of Biological Chemistry. 254(22). 11367–11373. 506 indexed citations breakdown →
18.
Brown, M S & J L Goldstein. (1979). Receptor-mediated endocytosis: insights from the lipoprotein receptor system.. Proceedings of the National Academy of Sciences. 76(7). 3330–3337. 560 indexed citations breakdown →
19.
Ho, Y K, et al.. (1977). Regulation of cholesterol synthesis by low density lipoprotein in isolated human lymphocytes. The Journal of Experimental Medicine. 145(6). 1531–1549. 127 indexed citations
20.
Milman, Gregory, J L Goldstein, Edward M. Scolnick, & T. Caskey. (1969). PEPTIDE CHAIN TERMINATION, III. STIMULATION OF in vitro TERMINATION. Proceedings of the National Academy of Sciences. 63(1). 183–190. 74 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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