J. Evan Sadler

24.8k total citations · 3 hit papers
190 papers, 17.9k citations indexed

About

J. Evan Sadler is a scholar working on Hematology, Immunology and Molecular Biology. According to data from OpenAlex, J. Evan Sadler has authored 190 papers receiving a total of 17.9k indexed citations (citations by other indexed papers that have themselves been cited), including 145 papers in Hematology, 65 papers in Immunology and 38 papers in Molecular Biology. Recurrent topics in J. Evan Sadler's work include Platelet Disorders and Treatments (110 papers), Complement system in diseases (59 papers) and Blood groups and transfusion (53 papers). J. Evan Sadler is often cited by papers focused on Platelet Disorders and Treatments (110 papers), Complement system in diseases (59 papers) and Blood groups and transfusion (53 papers). J. Evan Sadler collaborates with scholars based in United States, Japan and Italy. J. Evan Sadler's co-authors include X. Long Zheng, Steven R. Lentz, Elaine M. Majerus, James C. Paulson, A. Tulinsky, K. Padmanabhan, Joseph D. Ferrara, Manuel Tsiang, Patricia J. Anderson and Robert L. Hill and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

J. Evan Sadler

187 papers receiving 17.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

BIOCHEMISTRY AND GENETICS OF VON WILLEBRAND FACTOR

1998 1.1k citations J. Evan Sadler profile →
Structure of von Willebrand Factor-cleaving Protease (ADAMTS13), a Metalloprotease Involved in Thrombotic Thrombocytopenic Purpura

2001 646 citations X. Long Zheng, J. Evan Sadler et al. Journal of Biological Chemistry profile →
von Willebrand disease (VWD): evidence‐based diagnosis and management guidelines, the National Heart, Lung, and Blood Institute (NHLBI) Expert Panel report (USA) ¹

2008 630 citations William L. Nichols, Allison James et al. profile →

Peers

Countries citing papers authored by J. Evan Sadler

Since Specialization

Citations

This map shows the geographic impact of J. Evan Sadler's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. Evan Sadler with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. Evan Sadler more than expected).

Fields of papers citing papers by J. Evan Sadler

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. Evan Sadler. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. Evan Sadler. The network helps show where J. Evan Sadler may publish in the future.

Co-authorship network of co-authors of J. Evan Sadler

This figure shows the co-authorship network connecting the top 25 collaborators of J. Evan Sadler. A scholar is included among the top collaborators of J. Evan Sadler based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with J. Evan Sadler. J. Evan Sadler is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Phylogenetic and functional analysis of ADAMTS13 identifies highly conserved domains essential for allosteric regulation 2019 ·Blood ·Joshua Muia, Jian Zhu, Suellen Greco, Karen Vanhoorelbeke, Garima Gupta, Lisa A. Westfield, J. Evan Sadler	24
2	Exploring the “minimal” structure of a functional ADAMTS13 by mutagenesis and small-angle X-ray scattering 2019 ·Blood ·Jian Zhu, Joshua Muia, Garima Gupta, Lisa A. Westfield, Karen Vanhoorelbeke, Niraj H. Tolia, J. Evan Sadler	22
3	Pathophysiology of thrombotic thrombocytopenic purpura 2017 ·Blood ·J. Evan Sadler	166
4	Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS‐13 2015 ·Journal of Thrombosis and Haemostasis ·Louis Deforche, Elien Roose, Aline Vandenbulcke, Nele Vandeputte, Hendrik B. Feys, Timothy A. Springer, Li-Zhi Mi, Joshua Muia, J. Evan Sadler, Kenji Soejima, Hanspeter Rottensteiner, Hans Deckmyn, Simon F. De Meyer, Karen Vanhoorelbeke	56
5	Allosteric activation of ADAMTS13 by von Willebrand factor 2014 ·Proceedings of the National Academy of Sciences ·Joshua Muia, Jian Zhu, Garima Gupta, Sandra L. Haberichter, Kenneth D. Friedman, Hendrik B. Feys, Louis Deforche, Karen Vanhoorelbeke, Lisa A. Westfield, Robyn Roth, Niraj H. Tolia, John E. Heuser, J. Evan Sadler	100
6	An optimized fluorogenic ADAMTS13 assay with increased sensitivity for the investigation of patients with thrombotic thrombocytopenic purpura 2013 ·Journal of Thrombosis and Haemostasis ·Joshua Muia, Wei‐Qiang Gao, Sandra L. Haberichter, (unknown), Jian Zhu, Lisa A. Westfield, (unknown), Kenneth D. Friedman, J. Evan Sadler	32
7	Accelerated clearance alone explains ultra‐large multimers in von Willebrand disease Vicenza 2010 ·Journal of Thrombosis and Haemostasis ·András Gézsi, Ulrich Budde, István Deák, Eszter Nagy, (unknown), Ágota Schlammadinger, Z Boda, Tamás Masszi, J. Evan Sadler, Imre Bodó	19
8	A Structural Explanation for the Antithrombotic Activity of ARC1172, a DNA Aptamer that Binds von Willebrand Factor Domain A1 2009 ·Structure ·Ren‐Huai Huang, Daved H. Fremont, John L. Diener, Robert G. Schaub, J. Evan Sadler	75
9	Clinical and laboratory diagnosis of von Willebrand disease: A synopsis of the 2008 NHLBI/NIH guidelines 2009 ·American Journal of Hematology ·William L. Nichols, Margaret E. Rick, Thomas L. Ortel, Robert R. Montgomery, J. Evan Sadler, Barbara P. Yawn, Allison James, Mae B. Hultin, Marilyn J. Manco‐Johnson, Mark Weinstein	67
10	Provisional criteria for the diagnosis of VWD type 1: on behalf of the ISTH SSC Subcommittee on von Willebrand Factor 2005 ·Journal of Thrombosis and Haemostasis ·J. Evan Sadler, Francesco Rodeghiero	87
11	Crystal Structure of von Willebrand Factor A1 Domain Complexed with Snake Venom, Bitiscetin 2003 ·Journal of Biological Chemistry ·Nobuo Maita, Kenji Nishio, Etsuko Nishimoto, Taei Matsui, Yasuo Shikamoto, Takashi Morita, J. Evan Sadler, Hiroshi Mizuno	74
12	Mucin-like Domain of Enteropeptidase Directs Apical Targeting in Madin-Darby Canine Kidney Cells 2002 ·Journal of Biological Chemistry ·X. Long Zheng, J. Evan Sadler	23
13	Platelet Glycoprotein Ibα Binds to Thrombin Anion-binding Exosite II Inducing Allosteric Changes in the Activity of Thrombin 2001 ·Journal of Biological Chemistry ·Chester Q. Li, Alessandro Vindigni, J. Evan Sadler, Mark R. Wardell	51
14	Activation of Thrombin-activable Fibrinolysis Inhibitor Requires Epidermal Growth Factor-like Domain 3 of Thrombomodulin and Is Inhibited Competitively by Protein C 1998 ·Journal of Biological Chemistry ·Koichi Kokame, X. Long Zheng, J. Evan Sadler	79
15	Bovine Proenteropeptidase Is Activated by Trypsin, and the Specificity of Enteropeptidase Depends on the Heavy Chain 1997 ·Journal of Biological Chemistry ·Deshun Lu, Xin Yuan, X. Long Zheng, J. Evan Sadler	79
16	Structure of a nonadecapeptide of the fifth EGF domain of thrombomodulin complexed with thrombin 1994 ·Biochemistry ·Irimpan I. Mathews, K. Padmanabhan, A. Tulinsky, J. Evan Sadler	52
17	Commentary: a new classification for von Willebrand disease 1994 ·Blood ·J. Evan Sadler, HR Gralnick	43
18	Inhibition of thrombomodulin surface expression and protein C activation by the thrombogenic agent homocysteine. 1991 ·Journal of Clinical Investigation ·Steven R. Lentz, J. Evan Sadler	377
19	Molecular basis of von Willebrand disease type IIB. Candidate mutations cluster in one disulfide loop between proposed platelet glycoprotein Ib binding sequences. 1991 ·Journal of Clinical Investigation ·Anna M. Randi, Ian Rabinowitz, D J Mancuso, Pier Mannuccio Mannucci, J. Evan Sadler	94
20	Equilibrium binding of thrombin to recombinant human thrombomodulin: effect of hirudin, fibrinogen, factor Va, and peptide analogs 1990 ·Biochemistry ·Manuel Tsiang, Steven R. Lentz, William A. Dittman, Duanzhi Wen, (unknown), J. Evan Sadler	83

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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