Wolfram Ruf

20.4k total citations · 1 hit paper
280 papers, 15.7k citations indexed

About

Wolfram Ruf is a scholar working on Hematology, Genetics and Molecular Biology. According to data from OpenAlex, Wolfram Ruf has authored 280 papers receiving a total of 15.7k indexed citations (citations by other indexed papers that have themselves been cited), including 212 papers in Hematology, 83 papers in Genetics and 40 papers in Molecular Biology. Recurrent topics in Wolfram Ruf's work include Blood Coagulation and Thrombosis Mechanisms (195 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (77 papers) and Hemophilia Treatment and Research (63 papers). Wolfram Ruf is often cited by papers focused on Blood Coagulation and Thrombosis Mechanisms (195 papers), Coagulation, Bradykinin, Polyphosphates, and Angioedema (77 papers) and Hemophilia Treatment and Research (63 papers). Wolfram Ruf collaborates with scholars based in United States, Germany and Netherlands. Wolfram Ruf's co-authors include Barbara M. Mueller, Thomas S. Edgington, Matthias Riewald, Jasimuddin Ahamed, Henri H. Versteeg, Florence Schaffner, Ramona J. Petrovan, Andrea S. Rothmeier, Fahumiya Samad and Craig D. Dickinson and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Wolfram Ruf

272 papers receiving 15.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Activation of Endothelial Cell Protease Activated Receptor 1 by the Protein C Pathway

2002 685 citations Matthias Riewald, Barbara M. Mueller et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Wolfram Ruf United States	70	9.1k	4.0k	3.5k	2.4k	2.2k	280	15.7k
Lawrence F. Brass United States	69	6.7k 0.7×	3.8k 1.0×	2.3k 0.6×	2.0k 0.9×	1.1k 0.5×	188	13.3k
Mortimer Poncz United States	65	6.7k 0.7×	3.5k 0.9×	1.8k 0.5×	2.1k 0.9×	625 0.3×	287	13.3k
J. Evan Sadler United States	77	10.9k 1.2×	4.2k 1.1×	2.6k 0.7×	5.5k 2.3×	1.1k 0.5×	190	17.9k
Jay L. Degen United States	66	4.8k 0.5×	3.8k 0.9×	1.3k 0.4×	1.7k 0.7×	3.5k 1.6×	151	15.3k
Thomas S. Edgington United States	65	6.0k 0.7×	4.0k 1.0×	1.9k 0.6×	2.9k 1.2×	2.4k 1.1×	204	14.4k
Yale Nemerson United States	58	7.9k 0.9×	2.2k 0.6×	2.2k 0.6×	1.6k 0.7×	1.1k 0.5×	145	12.7k
Walter Kisiel United States	57	6.6k 0.7×	3.1k 0.8×	2.3k 0.7×	1.0k 0.4×	1.7k 0.8×	165	11.1k
Michael C. Berndt Australia	72	8.4k 0.9×	3.8k 1.0×	999 0.3×	2.8k 1.2×	847 0.4×	234	15.3k
Joseph E. Italiano United States	50	5.1k 0.6×	2.9k 0.7×	1.0k 0.3×	1.6k 0.7×	761 0.4×	133	9.7k
David J. Loskutoff United States	77	7.0k 0.8×	5.3k 1.3×	1.4k 0.4×	2.2k 0.9×	8.5k 3.9×	199	19.5k

Countries citing papers authored by Wolfram Ruf

Since Specialization

Citations

This map shows the geographic impact of Wolfram Ruf's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Wolfram Ruf with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Wolfram Ruf more than expected).

Fields of papers citing papers by Wolfram Ruf

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Wolfram Ruf. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Wolfram Ruf. The network helps show where Wolfram Ruf may publish in the future.

Co-authorship network of co-authors of Wolfram Ruf

This figure shows the co-authorship network connecting the top 25 collaborators of Wolfram Ruf. A scholar is included among the top collaborators of Wolfram Ruf based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Wolfram Ruf. Wolfram Ruf is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hummel, Regina, et al.. (2025). Protease-activated receptor 4 deficiency increases mortality, intracranial bleeding, and blood-brain barrier impairment following traumatic brain injury in mice. Research and Practice in Thrombosis and Haemostasis. 9(8). 103238–103238.

Thaler, J., Carla Tripisciano, Chi M. Hau, et al.. (2024). Saliva of persons with hemophilia A triggers coagulation via extrinsic tenase complexes. Blood. 144(25). 2666–2677.

Minciacchi, Valentina R., Jimena Bravo, Raquel Pereira, et al.. (2024). Differential inflammatory conditioning of the bone marrow by acute myeloid leukemia and its impact on progression. Blood Advances. 8(19). 4983–4996. 8 indexed citations

Bochenek, Magdalena L., Rajinikanth Gogiraju, Stéphane Robert, et al.. (2024). Endothelial PTP1B Deletion Promotes VWF Exocytosis and Venous Thromboinflammation. Circulation Research. 134(10). e93–e111. 6 indexed citations

Kespohl, Meike, Carl Christoph Goetzke, Nadine Althof, et al.. (2024). TF-FVIIa PAR2-β-Arrestin Signaling Sustains Organ Dysfunction in Coxsackievirus B3 Infection of Mice. Arteriosclerosis Thrombosis and Vascular Biology. 44(4). 843–865. 1 indexed citations

Thaler, J., et al.. (2023). Saliva and urine from persons with hemophilia A trigger coagulation bypassing factor VIII. Hämostaseologie. 43(S 01). S48–S49. 1 indexed citations

Morodomi, Yosuke, Sachiko Kanaji, Brian M. Sullivan, et al.. (2022). Inflammatory platelet production stimulated by tyrosyl-tRNA synthetase mimicking viral infection. Proceedings of the National Academy of Sciences. 119(48). e2212659119–e2212659119. 6 indexed citations

Raker, Verena, Detlef Becker, Matthias Bros, et al.. (2022). Protease‐ and cell type–specific activation of protease‐activated receptor 2 in cutaneous inflammation. Journal of Thrombosis and Haemostasis. 20(12). 2823–2836. 8 indexed citations

Kocatürk, Begüm, Araci M. R. Rondon, Rob F. P. van den Akker, et al.. (2022). Integrin regulation by tissue factor promotes cancer stemness and metastatic dissemination in breast cancer. Oncogene. 41(48). 5176–5185. 15 indexed citations

10.

Haist, Maximilian, Henner Stege, Claudine Graf, et al.. (2021). Anticoagulation with Factor Xa Inhibitors Is Associated with Improved Overall Response and Progression-Free Survival in Patients with Metastatic Malignant Melanoma Receiving Immune Checkpoint Inhibitors—A Retrospective, Real-World Cohort Study. Cancers. 13(20). 5103–5103. 34 indexed citations

11.

Lagrange, Jérémy, Stefanie Finger, Sabine Kossmann, et al.. (2020). Angiotensin II Infusion Leads to Aortic Dissection in LRP8 Deficient Mice. International Journal of Molecular Sciences. 21(14). 4916–4916. 5 indexed citations

12.

Lagrange, Jérémy, Sabine Kossmann, Wolfram Ruf, & Philip Wenzel. (2020). Lack of LRP8 triggers the formation of aortic dissection in angiotensin II infused mice. Archives of Cardiovascular Diseases Supplements. 12(1). 134–135. 1 indexed citations

13.

Graf, Claudine, Petra Wilgenbus, Fédérico Marini, et al.. (2019). Myeloid cell–synthesized coagulation factor X dampens antitumor immunity. Science Immunology. 4(39). 94 indexed citations

14.

Müller‐Calleja, Nadine, et al.. (2018). Complement C5 but not C3 is expendable for tissue factor activation by cofactor-independent antiphospholipid antibodies. Blood Advances. 2(9). 979–986. 38 indexed citations

15.

Koizume, Shiro, Shin Ito, Etsuko Miyagi, et al.. (2012). HIF2α-Sp1 interaction mediates a deacetylation-dependent FVII- gene activation under hypoxic conditions in ovarian cancer cells. Nucleic Acids Research. 40(12). 5389–5401. 40 indexed citations

16.

Koizume, Shiro, Naho Yokota, Etsuko Miyagi, et al.. (2009). Hepatocyte Nuclear Factor-4–Independent Synthesis of Coagulation Factor VII in Breast Cancer Cells and Its Inhibition by Targeting Selective Histone Acetyltransferases. Molecular Cancer Research. 7(12). 1928–1936. 38 indexed citations

17.

Ruf, Wolfram. (2009). Tissue factor-PAR2 signaling crosstalk in cancer and angiogenesis. 1(9).

18.

Şen, Mehmet, et al.. (2009). Spectroscopic Characterization of Successive Phosphorylation of the Tissue Factor Cytoplasmic Region. PubMed. 3(1). 58–64. 21 indexed citations

19.

Yokota, Naho, Shiro Koizume, Etsuko Miyagi, et al.. (2009). Self-production of tissue factor-coagulation factor VII complex by ovarian cancer cells. British Journal of Cancer. 101(12). 2023–2029. 66 indexed citations

20.

Riewald, Matthias, et al.. (1999). Tumor cell adhesion and migration supported by interaction of a receptor-protease complex with its inhibitor. Journal of Clinical Investigation. 104(9). 1213–1221. 83 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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