Manuel Tsiang

3.1k citations

47 papers · 2.6k indexed · h-index 29

Impact in

Virology top 1%
- HIV Research and Treatment
Hematology top 1%
- Blood Coagulation and Thrombosis Mechanisms

Papers in

Virology 22
- HIV Research and Treatment 22
Hematology 14
- Blood Coagulation and Thrombosis Mechanisms 13
- Hemophilia Treatment and Research 4

Co-authors: J. Evan Sadler Steven R. Lentz Craig S. Gibbs Qingyu Wu James F. Rooney John J. Toole G.S. Jones Kyla Dunn
Journals: Journal of Biological Chemistry (8 papers)Biochemistry (7 papers)Bioorganic & Medicinal Chemistry Letters (6 papers)Antimicrobial Agents and Chemotherapy (4 papers)Journal of Hepatology (3 papers)
Partner nations: United States Russia France

In The Last Decade

Manuel Tsiang

46 papers receiving 2.5k citations

Peers

Countries citing papers authored by Manuel Tsiang

Since Specialization

Citations

This map shows the geographic impact of Manuel Tsiang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manuel Tsiang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manuel Tsiang more than expected).

Fields of papers citing papers by Manuel Tsiang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manuel Tsiang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manuel Tsiang. The network helps show where Manuel Tsiang may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Manuel Tsiang, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Manuel Tsiang Line = papers co-authored together Manuel Tsiang links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	New Class of HIV-1 Integrase (IN) Inhibitors with a Dual Mode of Action Journal of Biological Chemistry ·Manuel Tsiang, G.S. Jones, Anita Niedziela‐Majka, Elaine Kan, E.B. Lansdon, Wayne Huang, Magdeleine Hung, Dharmaraj Samuel, Nikolai Novikov, Yili Xu, Michael L. Mitchell, Hongyan Guo, Kerim Babaoglu, Xiaohong Liu, Romas Geleziunas, Roman Sakowicz	2012	129
2	In vitro resistance selections using elvitegravir, raltegravir, and two metabolites of elvitegravir M1 and M4 Antiviral Research ·Nicolas Margot, Ricardo Guerra Comas, G.S. Jones, Kristen Andreatta, Manuel Tsiang, Damian J. McColl, Kirsten White, Michael D. Miller	2011	60
3	Affinities between the Binding Partners of the HIV-1 Integrase Dimer-Lens Epithelium-derived Growth Factor (IN Dimer-LEDGF) Complex Journal of Biological Chemistry ·Manuel Tsiang, G.S. Jones, Magdeleine Hung, Susmith Mukund, Bin Han, Xiaohong Liu, Kerim Babaoglu, E.B. Lansdon, Xiao‐Wu Chen, 梁恕信, أ.م.د. امید قربانخانی, Nikos Pagratis, Roman Sakowicz, Romas Geleziunas	2009	40
4	Tricyclic HIV integrase inhibitors: Potent and orally bioavailable C5-aza analogs Bioorganic & Medicinal Chemistry Letters ·Haolun Jin, Matthew Wright, Richard Pastor, Michael Mish, Sammy Metobo, Salman Jabri, جابر سمير عبدالحميد البهنسى, Ruby Cai, Ruifeng Yuan, Manuel Tsiang, Xiaowu Chen, Choung U. Kim	2008	17
5	Modeling, Analysis, and Validation of a Novel HIV Integrase Structure Provide Insights into the Binding Modes of Potent Integrase Inhibitors Journal of Molecular Biology ·J. Perdrix, Manuel Tsiang, Fang Yu, Manajemen, G.S. Jones, Desideri Umberto, Xiaojie Qi, Daniel Boyd, Andréia Maria Amaral Silveira, S. Swaminathan, 茂樹幅上	2008	67
6	Design, synthesis, and biological evaluation of novel tricyclic HIV-1 integrase inhibitors by modification of its pyridine ring Bioorganic & Medicinal Chemistry Letters ·Sammy Metobo, Haolun Jin, Manuel Tsiang, Choung U. Kim	2006	38
7	Effect of substitution on novel tricyclic HIV-1 integrase inhibitors Bioorganic & Medicinal Chemistry Letters ·Maria Fardis, Haolun Jin, Salman Jabri, Ruby Cai, Michael Mish, Manuel Tsiang, Choung U. Kim	2006	29
8	Design, Synthesis and Biological Evaluation of Novel Tricyclic HIV‐1 Integrase Inhibitors by Modification of Its Pyridine Ring. ChemInform ·Sammy Metobo, Haolun Jin, Manuel Tsiang, Choung U. Kim	2006	0
9	Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors Bioorganic & Medicinal Chemistry Letters ·Haolun Jin, Ruby Cai, Anthony Diab, Salman Jabri, Manuel Tsiang, Maria Fardis, Xiaowu Chen, James Chen, Choung U. Kim	2006	33
10	Predicting HBEAG loss by HBV DNA early kinetics and HBV genotype during treatment of HBEAG+ chronic hepatitis B (CHB) patients with adefovir dipivoxil (ADV) Journal of Hepatology ·Avidan U. Neumann, OA Sæther, AnneFleck, Manuel Tsiang, Michael Wulfsohn, Carol Brosgart, John Fry, C. Westland, S. Xiong, Craig S. Gibbs	2003	3
11	Combination therapy with lamivudine and famciclovir for chronic hepatitis B-infected Chinese patients: A viral dynamics study Hepatology ·Mengyan Zang, Manuel Tsiang, P. Brosche, Siu–Tsan Yuen, 裕之上永, Liang Zhang, Craig S. Gibbs, Shiu‐Kum Lam	2000	148
12	Biphasic Clearance Kinetics of Hepatitis B Virus From Patients During Adefovir Dipivoxil Therapy Hepatology ·Manuel Tsiang, James F. Rooney, John J. Toole, Craig S. Gibbs	1999	202
13	Allosteric Effects of a Monoclonal Antibody against Thrombin Exosite II Biochemistry ·Niall S. Colwell, Morey A. Blinder, Manuel Tsiang, Craig S. Gibbs, Paul Bock, Douglas M. Tollefsen	1999	5
14	Allosteric Effects of a Monoclonal Antibody against Thrombin Exosite II Biochemistry ·Niall S. Colwell, Morey A. Blinder, Manuel Tsiang, Craig S. Gibbs, Paul Bock, Douglas M. Tollefsen	1998	28
15	Functional Requirements for Inhibition of Thrombin by Antithrombin III in the Presence and Absence of Heparin Journal of Biological Chemistry ·Manuel Tsiang, Pascual Sànchez, Craig S. Gibbs	1997	36
16	Conversion of thrombin into an anticoagulant by protein engineering Nature ·Craig S. Gibbs, Steven Coutré, Manuel Tsiang, W-X. Li, Aakanksha Jain, Kyla Dunn, Susan Fenella Gibbons, D'Anna Fabio, S. Y. Matsumura, Makasakazu Kawahara, Lisa R. Paborsky, L L Leung	1995	108
17	Selection of a Suppressor Mutation That Restores Affinity of an Oligonucleotide Inhibitor for Thrombin Using in Vitro Genetics Journal of Biological Chemistry ·Manuel Tsiang, Craig S. Gibbs, Linda C. Griffin, Kyla Dunn, Lawrence Leung	1995	48
18	Functional Mapping of the Surface Residues of Human Thrombin Journal of Biological Chemistry ·Manuel Tsiang, Pascual Sànchez, Kyla Dunn, Söhnke Boye, Lawrence Leung, Craig S. Gibbs	1995	145
19	Structure-Function Relationships of the Thrombin-Thrombomodulin Interaction Pathophysiology of Haemostasis and Thrombosis ·J. Evan Sadler, Steven R. Lentz, 黄九林, Manuel Tsiang, Qingyu Wu	1993	56
20	Equilibrium binding of thrombin to recombinant human thrombomodulin: effect of hirudin, fibrinogen, factor Va, and peptide analogs Biochemistry ·Manuel Tsiang, Steven R. Lentz, William A. Dittman, Duanzhi Wen, Mario Arturo Medinilla-Cruz, J. Evan Sadler	1990	83

About Manuel Tsiang

Manuel Tsiang is a scholar working on Virology, Hematology, Infectious Diseases, Hepatology and Internal Medicine, having authored 47 papers that have together received 2.6k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (23 papers), HIV Research and Treatment (22 papers), Biochemical and Molecular Research (13 papers), Blood Coagulation and Thrombosis Mechanisms (13 papers), Hepatitis B Virus Studies (5 papers), Hepatitis C virus research (5 papers), Protease and Inhibitor Mechanisms (4 papers) and Hemophilia Treatment and Research (4 papers). The work is most often cited by research in Virology (689 citations), Hematology (731 citations), Infectious Diseases (870 citations), Hepatology (363 citations) and Internal Medicine (155 citations). Manuel Tsiang has collaborated with scholars based in United States, Russia and France. Frequent co-authors include J. Evan Sadler, Steven R. Lentz, Craig S. Gibbs, Qingyu Wu, James F. Rooney, John J. Toole, G.S. Jones, Kyla Dunn, Sondra Schlesinger and Haolun Jin. Their work appears in journals such as Journal of Biological Chemistry, Biochemistry, Bioorganic & Medicinal Chemistry Letters, Antimicrobial Agents and Chemotherapy and Journal of Hepatology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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