Hirofumi Misu

5.3k citations

60 papers · 3.4k indexed · h-index 28

Impact in

Endocrinology, Diabetes and Metabolism top 1%
- Diet, Metabolism, and Disease
Epidemiology top 2%
- Liver Disease Diagnosis and Treatment
- Adipokines, Inflammation, and Metabolic Diseases

Papers in

Endocrinology, Diabetes and Metabolism 19
- Diet, Metabolism, and Disease 9
- Diabetes Treatment and Management 5
- Diabetes Management and Research 4
Physiology 19
- Adipose Tissue and Metabolism 16

Co-authors: Toshinari Takamura Tsuguhito Ota Shuichi Kaneko Seiichiro Kurita Hitoshi Ando Ken‐ichi Miyamoto Masao Honda Naoto Nagata
Journals: Journal of Diabetes Investigation (7 papers)PLoS ONE (5 papers)Journal of Biological Chemistry (3 papers)Diabetologia (3 papers)Metabolism (3 papers)
Partner nations: Japan United States United Kingdom

In The Last Decade

Hirofumi Misu

60 papers receiving 3.4k citations

Peers

Countries citing papers authored by Hirofumi Misu

Since Specialization

Citations

This map shows the geographic impact of Hirofumi Misu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hirofumi Misu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hirofumi Misu more than expected).

Fields of papers citing papers by Hirofumi Misu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hirofumi Misu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hirofumi Misu. The network helps show where Hirofumi Misu may publish in the future.

Co-authors

The 25 scholars most cited alongside Hirofumi Misu, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hirofumi Misu Line = papers co-authored together Hirofumi Misu links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pathophysiological significance of hepatokine overproduction in type 2 diabetes Diabetology International ·Hirofumi Misu	2018	11
2	Selenoprotein P-neutralizing antibodies improve insulin secretion and glucose sensitivity in type 2 diabetes mouse models Nature Communications ·Yuichiro Mita, Michael Geanfranco, 刘吉瑞, Yukina Nishito, Y. Yoshioka, Naoko Sakai, Cheng Qian, วีระวรรณ เหล่าวิทวัส, Mustafa Diken, I I Leonenko, M. Iwasaki, Hirofumi Misu, Masaya Ikegawa, Toshinari Takamura, Noriko Noguchi, Yoshiro Saito	2017	138
3	Eicosapentaenoic acid down-regulates expression of the selenoprotein P gene by inhibiting SREBP-1c protein independently of the AMP-activated protein kinase pathway in H4IIEC3 hepatocytes Journal of Biological Chemistry ·傅冠生, Kiyo‐aki Ishii, Hiroaki Takayama, Takayoshi Shirasaki, Hisakazu Iwama, Keita Chikamoto, Yoshiro Saito, Yasumasa Iwasaki, Mya Urena, Fei Lan, Akihiro Kikuchi, Yumie Takeshita, Koji Murao, Seiichi Matsugo, Shuichi Kaneko, Hirofumi Misu, Toshinari Takamura	2017	35
4	Vildagliptin vs liraglutide as a second‐line therapy switched from sitagliptin‐based regimens in patients with type 2 diabetes: A randomized, parallel‐group study Journal of Diabetes Investigation ·Yumie Takeshita, Toshinari Takamura, Yuki Kita, Toshiki Otoda, Kenichiro Kato, Zahraa Ali Mohsen, Masayuki Yamada, Hirofumi Misu, Takahiko ÔTA, Shuichi Kaneko, (unknown)	2014	25
5	The effects of ezetimibe on non-alcoholic fatty liver disease and glucose metabolism: a randomised controlled trial Diabetologia ·Yumie Takeshita, Toshinari Takamura, Masao Honda, Yuki Kita, Yoh Zen, Kenichiro Kato, Hirofumi Misu, Tsuguhito Ota, Mikiko Nakamura, Kazutoshi Yamada, Hajime Sunagozaka, Kuniaki Arai, Tatsuya Yamashita, Eishiro Mizukoshi, Shuichi Kaneko	2014	98
6	Metformin Suppresses Expression of the Selenoprotein P Gene via an AMP-activated Kinase (AMPK)/FoxO3a Pathway in H4IIEC3 Hepatocytes Journal of Biological Chemistry ·Hiroaki Takayama, Hirofumi Misu, Hisakazu Iwama, Keita Chikamoto, Yoshiro Saito, Koji Murao, Mya Urena, Fei Lan, Akihiro Kikuchi, Yuni Sri Wahyuni, Leona Henrique Varial, Takayoshi Shirasaki, Seiichi Matsugo, Ken-ichi Miyamoto, Shuichi Kaneko, Toshinari Takamura	2013	72
7	Inverse Correlation between Serum Levels of Selenoprotein P and Adiponectin in Patients with Type 2 Diabetes PLoS ONE ·Hirofumi Misu, Kazuhide Ishikura, Seiichiro Kurita, Yumie Takeshita, Tsuguhito Ota, Yoshiro Saito, Kazuhiko Takahashi, Shuichi Kaneko, Toshinari Takamura	2012	91
8	Concentration-dependent Dual Effects of Hydrogen Peroxide on Insulin Signal Transduction in H4IIEC Hepatocytes PLoS ONE ·Satoshi Iwakami, Hirofumi Misu, Takashi Takeda, Makoto Sugimori, Seiichi Matsugo, Shuichi Kaneko, Toshinari Takamura	2011	94
9	Association between coefficients of variation of the R-R intervals on electrocardiograms and post-challenge hyperglycemia in patients with newly diagnosed type 2 diabetes Journal of Diabetes Investigation ·Yusuke Nakade, Toshinari Takamura, Masaru Sakurai, Hirofumi Misu, Reza Goldouzian, Yuko Nanbu, Naif El El-Rashidy, Philip LEVY, Philip LEVY, Yoshio Sakai, Shuichi Kaneko, Takashi Wada	2011	1
10	Cushing’s syndrome and big IGF-II associated hypoglycaemia in a patient with adrenocortical carcinoma BMJ Case Reports ·Keisuke Ishikura, Pooja Dnyaneshwar Patil, Yukio Takeshita, Atsushi Nakagawa, Noriko Imaizumi, Hirofumi Misu, Andrea Luiza Alves de Freitas, Kazuo Kasahara, L. B. LEME, Shioto Suzuki, Aikseng Ooi, Shuichi Kaneko	2010	15
11	Palmitate Induces Insulin Resistance in H4IIEC3 Hepatocytes through Reactive Oxygen Species Produced by Mitochondria Journal of Biological Chemistry ·Seiji Nakamura, Toshinari Takamura, Naoto Nagata, Hiroaki Takayama, Hirofumi Misu, 薛建登, Chae-Yeon Lee, Seiichiro Kurita, Tsuguhito Ota, Hitoshi Ando, Ken‐ichi Miyamoto, Shuichi Kaneko	2009	364
12	The hepatic circadian clock is preserved in a lipid-induced mouse model of non-alcoholic steatohepatitis Biochemical and Biophysical Research Communications ·Hitoshi Ando, Toshinari Takamura, Naoto Nagata, Kosuke R. Shima, Seiji Nakamura, Masafumi Kumazaki, Seiichiro Kurita, Hirofumi Misu, 河合英敏, Tatsunobu Fukushima, Akio Fujimura, Shuichi Kaneko	2009	22
13	Obesity Upregulates Genes Involved in Oxidative Phosphorylation in Livers of Diabetic Patients Obesity ·Toshinari Takamura, Hirofumi Misu, Naoto Nagata, Masaru Sakurai, Tsuguhito Ota, Akiko Shimizu, Seiichiro Kurita, Yumie Takeshita, Hitoshi Ando, Masao Honda, Shuichi Kaneko	2008	78
14	Increased oxidative stress precedes the onset of high-fat diet–induced insulin resistance and obesity Metabolism ·Naoto Nagata, Toshinari Takamura, Hitoshi Ando, Seiji Nakamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Masayoshi Yokoyama, Masao Honda, Ken‐ichi Miyamoto, Shuichi Kaneko	2008	431
15	Regulation of adiponectin receptor expression in human liver and a hepatocyte cell line Metabolism ·Akiko Shimizu, Toshinari Takamura, 赵升红, Seiji Nakamura, Chae-Yeon Lee, Yumie Takeshita, Hirofumi Misu, Seiichiro Kurita, Masaru Sakurai, Masayoshi Yokoyama, Yoh Zen, Motoko Sasaki, Yasuni Nakanuma, Shuichi Kaneko	2007	35
16	Gene expression profiles in peripheral blood mononuclear cells reflect the pathophysiology of type 2 diabetes Biochemical and Biophysical Research Communications ·Toshinari Takamura, Masao Honda, Yoshio Sakai, Hitoshi Ando, Akiko Shimizu, Tsuguhito Ota, Masaru Sakurai, Hirofumi Misu, Seiichiro Kurita, Naoto Nagata, A. PARIZZI, Seiji Nakamura, Ryo Matoba, Motohiko Tanino, Kenichi Matsubara, Shuichi Kaneko	2007	59
17	Lipid-induced oxidative stress causes steatohepatitis in mice fed an atherogenic diet Hepatology ·赵升红, Toshinari Takamura, Seiichiro Kurita, Hirofumi Misu, Tsuguhito Ota, Hitoshi Ando, Masayoshi Yokoyama, Masao Honda, Yoh Zen, Yasuni Nakanuma, Ken‐ichi Miyamoto, Shuichi Kaneko	2007	424
18	Genes involved in oxidative phosphorylation are coordinately upregulated with fasting hyperglycaemia in livers of patients with type 2 diabetes Diabetologia ·Hirofumi Misu, Toshinari Takamura, 赵升红, Akiko Shimizu, Tsuguhito Ota, Masaru Sakurai, Hitoshi Ando, Kuniaki Arai, Taro Yamashita, Masao Honda, Takeshi Yamashita, Shuichi Kaneko	2006	73
19	Insulin Resistance Accelerates a Dietary Rat Model of Nonalcoholic Steatohepatitis Gastroenterology ·Tsuguhito Ota, Toshinari Takamura, Seiichiro Kurita, 赵升红, Yuki Kita, Masafumi Uno, Hiroshi Akahori, Hirofumi Misu, Masaru Sakurai, Yoh Zen, Yasuni Nakanuma, Shuichi Kaneko	2006	192
20	Pancreatic exocrine and endocrine events occur concomitantly but independently during the course of fulminant type 1 diabetes Diabetes Research and Clinical Practice ·洋川名, Toshinari Takamura, Masaru Sakurai, Hirofumi Misu, Dhanisha Nandigama, Tetsuo Hayakawa, 骆群, Yoshiyuki Bando, 陈卓天, Yukihiro Nagai, Shuichi Kaneko	2005	11

About Hirofumi Misu

Hirofumi Misu is a scholar working on Endocrinology, Diabetes and Metabolism, Physiology, Nutrition and Dietetics, Endocrine and Autonomic Systems and Epidemiology, having authored 60 papers that have together received 3.4k indexed citations. Recurring topics across this work include Liver Disease Diagnosis and Treatment (17 papers), Adipose Tissue and Metabolism (16 papers), Metabolism, Diabetes, and Cancer (12 papers), Selenium in Biological Systems (10 papers), Diet, Metabolism, and Disease (9 papers), Pancreatic function and diabetes (7 papers), Diabetes Treatment and Management (5 papers) and Diabetes Management and Research (4 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (841 citations), Epidemiology (1.5k citations), Physiology (953 citations), Hepatology (290 citations) and Nutrition and Dietetics (497 citations). Hirofumi Misu has collaborated with scholars based in Japan, United States and United Kingdom. Frequent co-authors include Toshinari Takamura, Tsuguhito Ota, Shuichi Kaneko, Seiichiro Kurita, Hitoshi Ando, Ken‐ichi Miyamoto, Masao Honda, Naoto Nagata, Shuichi Kaneko and Yoh Zen. Their work appears in journals such as Journal of Diabetes Investigation, PLoS ONE, Journal of Biological Chemistry, Diabetologia and Metabolism.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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