Helen Chapman

2.3k citations

21 papers · 1.5k indexed · h-index 15

Endocrine and Autonomic Systems top 2%
Cognitive Neuroscience top 5%
Physiology top 5%
- Adipose Tissue and Metabolism 7
Experimental and Cognitive Psychology top 5%
Cellular and Molecular Neuroscience top 10%
- Neuropeptides and Animal Physiology 4
- Neuroscience and Neuropharmacology Research 3
Molecular Biology
- Receptor Mechanisms and Signaling 7
- Peroxisome Proliferator-Activated Receptors 4
- Metabolism, Diabetes, and Cancer 3
Animal Science and Zoology
- Pharmacological Effects and Assays 5
Neurology
- Parkinson's Disease Mechanisms and Treatments 4

Co-authors: John C. Clapham Jonathan R.S. Arch Andrea Haynes Paul Young Michael A. Cawthorne Stephen A. Smith Amanda Johns M. Tadayyon
Cited by: Endocrine and Autonomic Systems Cognitive Neuroscience Physiology
Journals: Journal of Biological Chemistry (1 paper)Diabetes (1 paper)Biochemical and Biophysical Research Communications (1 paper)
Partner nations: United Kingdom United States Australia

In The Last Decade

Helen Chapman

20 papers receiving 1.4k citations

Peers

Countries citing papers authored by Helen Chapman

Since Specialization

Citations

This map shows the geographic impact of Helen Chapman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Helen Chapman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Helen Chapman more than expected).

Fields of papers citing papers by Helen Chapman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Helen Chapman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Helen Chapman. The network helps show where Helen Chapman may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Helen Chapman, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Helen Chapman Line = papers co-authored together Helen Chapman links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The PPARγ agonist pioglitazone is effective in the MPTP mouse model of Parkinson's disease through inhibition of monoamine oxidase B British Journal of Pharmacology ·Leann P. Quinn,Barry Crook,Mark Hows,Martin Vidgeon-Hart,Helen Chapman,N. Upton,Andrew D. Medhurst,David Virley	2008	100
2	P1‐080: Ask1 kinase‐dead knock‐in mice and models of neurodegeneration Alzheimer s & Dementia ·Karen L. Philpott,Kim Brackenborough,Stephen D. Skaper,Claire I. Hobbs,Christopher J. Hille,Ryan P. Bingham,Laura Facci,Helen Chapman,David Howlett,Anthony Shillings,Jill Richardson,Janet Brownlees,Graham Duddy	2008	1
3	A beam-walking apparatus to assess behavioural impairments in MPTP-treated mice: Pharmacological validation with R-(−)-deprenyl Journal of Neuroscience Methods ·Leann P. Quinn,M.J. Perren,Kim Brackenborough,P.L. Woodhams,Martin Vidgeon-Hart,Helen Chapman,Menelas N. Pangalos,Neil Upton,David Virley	2007	34
4	Subthalamic nucleus neurones in slices from 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned mice show irregular, dopamine-reversible firing pattern changes, but without synchronous activity Neuroscience ·Claire Wilson,Diana Cash,Kevin Galley,Helen Chapman,M.G. Lacey,Ian M. Stanford	2006	35
5	Further validation of LABORAS™ using various dopaminergic manipulations in mice including MPTP-induced nigro-striatal degeneration Journal of Neuroscience Methods ·Leann P. Quinn,Tania O. Stean,Helen Chapman,Matthew T. Brown,Martin Vidgeon-Hart,Neil Upton,Andrew Billinton,David Virley	2006	36
6	Anorectic, thermogenic and anti-obesity activity of a selective orexin-1 receptor antagonist in ob/ob mice Regulatory Peptides ·Andrea Haynes,Helen Chapman,Colleen Taylor,Gary B.T. Moore,Michael A. Cawthorne,Mohammad Tadayyon,John C. Clapham,Jonathan R.S. Arch	2002	114
7	The Basal Proton Conductance of Skeletal Muscle Mitochondria from Transgenic Mice Overexpressing or Lacking Uncoupling Protein-3 Journal of Biological Chemistry ·Susana Cadenas,Karim S. Echtay,James A. Harper,Mika B. Jekabsons,Julie A. Buckingham,Evelyn Grau,Alejandro Abuin,Helen Chapman,John C. Clapham,Martin D. Brand	2002	177
8	Differential Regulation of Adipocytokine mRNAs by Rosiglitazone in db/db Mice Biochemical and Biophysical Research Communications ·Gary B.T. Moore,Helen Chapman,Julie C. Holder,Carolyn A. Lister,Valerie Piercy,Stephen A. Smith,John C. Clapham	2001	125
9	v- and t-SNARE protein expression in models of insulin resistance: normalization of glycemia by rosiglitazone treatment corrects overexpression of cellubrevin, vesicle-associated membrane protein-2, and syntaxin 4 in skeletal muscle of Zucker diabetic fatty rats. Diabetes ·Valerie H. Maier,Derek R. Melvin,Carolyn A. Lister,Helen Chapman,Gwyn W. Gould,Gerard J. Murphy	2000	34
10	A selective orexin-1 receptor antagonist reduces food consumption in male and female rats Regulatory Peptides ·Andrea Haynes,Brian A. Jackson,Helen Chapman,M. Tadayyon,Amanda Johns,Roderick A. Porter,Jonathan R.S. Arch	2000	263
11	Studies on a novel selective beta(3)-adrenoceptor agonist in human right atrial appendage and human white adipocytes British Journal of Pharmacology ·Jrs Arch,Kaumann Aj,Peter Molenaar,MV Sennitt,JM Berge,Helen Chapman,J.P. Kelly	1999	1
12	The contribution of classical (beta1/2-) and atypical beta-adrenoceptors to the stimulation of human white adipocyte lipolysis and right atrial appendage contraction by novel beta3-adrenoceptor agonists of differing selectivities. PubMed ·Matthew V. Sennitt,Alberto J. Kaumann,Peter Molenaar,Lee J. Beeley,Paul Young,John Kelly,Helen Chapman,Siân M. Henson,John M. Berge,David K. Dean,Nikesh R. Kotecha,Helen K.A. Morgan,Harshad K. Rami,Robert W. Ward,Mervyn Thompson,Shelagh Wilson,Stephen A. Smith,Michael A. Cawthorne,Michael J. Stock,Jonathan R.S. Arch	1998	53
13	Identification of High-Affinity Binding Sites for the Insulin Sensitizer Rosiglitazone (BRL-49653) in Rodent and Human Adipocytes Using a Radioiodinated Ligand for Peroxisomal Proliferator-Activated Receptor γ Journal of Pharmacology and Experimental Therapeutics ·Paul Young,Derek R. Buckle,Barrie C. C. Cantello,Helen Chapman,John C. Clapham,Paul J. Coyle,David Haigh,Richard M. Hindley,Julie C. Holder,Howard Kallender,Alison J. Latter,K. W. M. Lawrie,Danuta E. Mossakowska,Gregory Murphy,Lynne Roxbee Cox,Stephen A. Smith	1998	90
14	The Contribution of Classical (β1/2-) and Atypical β-Adrenoceptors to the Stimulation of Human White Adipocyte Lipolysis and Right Atrial Appendage Contraction by Novel β3-Adrenoceptor Agonists of Differing Selectivities Journal of Pharmacology and Experimental Therapeutics ·Matthew V. Sennitt,Alberto J. Kaumann,Peter Molenaar,Lee J. Beeley,Paul Young,John Kelly,Helen Chapman,Siân M. Henson,John M. Berge,David K. Dean,Nikesh R. Kotecha,Helen K.A. Morgan,Harshad K. Rami,Robert W. Ward,Mervyn Thompson,Shelagh Wilson,Stephen A. Smith,Michael A. Cawthorne,Michael J. Stock,Jonathan R.S. Arch	1998	23
15	A simplified template approach towards the synthesis of a potent beta-3 adrenoceptor agonist at the human receptor Bioorganic & Medicinal Chemistry Letters ·Lee J. Beeley,John M. Berge,Helen Chapman,David K. Dean,John Kelly,K. Lowden,Nikesh R. Kotecha,Helen K.A. Morgan,Harshad K. Rami,M. THOMPSON,Antonio Vong,Robert W. Ward	1997	8
16	The selectivity in vitro of the stereoisomers of the beta-3 adrenoceptor agonist BRL 37344. Journal of Pharmacology and Experimental Therapeutics ·Mabayoje A. Oriowo,Helen Chapman,David M. Kirkham,Matthew V. Sennitt,Robert Ruffolo,Michael A. Cawthorne	1996	33
17	Synthesis of a selective alpha-2A adrenoceptor antagonist, BRL 48962, and its characterization at cloned human alpha-adrenoceptors Bioorganic & Medicinal Chemistry ·Lee J. Beeley,John M. Berge,Helen Chapman,Paul Hieble,John Kelly,Diane P. Naselsky,Caroline M. Rockell,Paul Young	1995	8
18	Additional evidence for functional subclassification of alpha-2 adrenoceptors based on a new selective antagonist, SK&F 104856. Journal of Pharmacology and Experimental Therapeutics ·J. Paul Hieble,Anthony C. Sulpizio,Ruth Edwards,Helen Chapman,Paul Young,S.P. Roberts,T.P. Blackburn,Martyn Wood,Disha Shah,R M Demarinis	1991	2
19	Additional evidence for functional subclassification of alpha-2 adrenoceptors based on a new selective antagonist, SK&F 104856. PubMed ·J. Paul Hieble,Anthony C. Sulpizio,Ruth Edwards,Helen Chapman,Paul Young,S.P. Roberts,T.P. Blackburn,Martyn Wood,Disha Shah,R M Demarinis	1991	13
20	Novel α2-adrenoceptor antagonists show selectivity for α2A- and α2B-adrenoceptor subtypes European Journal of Pharmacology ·Paul Young,John M. Berge,Helen Chapman,Michael A. Cawthorne	1989	101

About Helen Chapman

Helen Chapman is a scholar working on Cellular and Molecular Neuroscience, Animal Science and Zoology and Endocrine and Autonomic Systems, having authored 21 papers that have together received 1.5k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (7 papers), Adipose Tissue and Metabolism (7 papers), Pharmacological Effects and Assays (5 papers), Peroxisome Proliferator-Activated Receptors (4 papers), Parkinson's Disease Mechanisms and Treatments (4 papers), Neuropeptides and Animal Physiology (4 papers), Neuroscience and Neuropharmacology Research (3 papers) and Metabolism, Diabetes, and Cancer (3 papers). The work is most often cited by research in Endocrine and Autonomic Systems (435 citations), Cognitive Neuroscience (369 citations) and Physiology (460 citations). Helen Chapman has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include John C. Clapham, Jonathan R.S. Arch, Andrea Haynes, Paul Young, Michael A. Cawthorne, Stephen A. Smith, Amanda Johns, M. Tadayyon, Roderick A. Porter and Brian A. Jackson. Their work appears in journals such as Journal of Biological Chemistry, Diabetes and Biochemical and Biophysical Research Communications.

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