Ruud H. Brakenhoff

21.7k citations

242 papers · 15.7k indexed · 6 hit papers · h-index 59

Molecular Biology top 0.5%
Oncology top 0.2%
Otorhinolaryngology top 0.01%
Cancer Research top 0.2%
Surgery top 0.5%

Co-authors: C. René Leemans Boudewijn J.M. Braakhuis Klaus Pantel Peter J.F. Snijders Maarten P. Tabor J. Alain Kummer Burkhard Brandt Elisabeth Bloemena
Topics: Head and Neck Cancer Studies (117 papers)Cancer-related Molecular Pathways (41 papers)Oral Health Pathology and Treatment (31 papers)
Cited by: Otorhinolaryngology Periodontics Cancer Research
Journals: Proceedings of the National Academy of Sciences Nucleic Acids Research Journal of Biological Chemistry
Partner nations: Netherlands United States Germany

In The Last Decade

Ruud H. Brakenhoff

237 papers receiving 15.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The molecular biology of head and neck cancer

2010 1.9k citations C. René Leemans, Boudewijn J.M. Braakhuis et al. profile →
Dissecting the metastatic cascade

2004 1.0k citations Klaus Pantel, Ruud H. Brakenhoff profile →
The molecular landscape of head and neck cancer

2018 936 citations C. René Leemans, Peter J.F. Snijders et al. profile →
A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implications.

2003 933 citations Boudewijn J.M. Braakhuis, C. René Leemans et al. profile →
Detection, clinical relevance and specific biological properties of disseminating tumour cells

2008 930 citations Klaus Pantel, Ruud H. Brakenhoff et al. profile →
A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen

2007 599 citations Serge Smeets, Peter J.F. Snijders et al. profile →

Peers

Countries citing papers authored by Ruud H. Brakenhoff

Since Specialization

Citations

This map shows the geographic impact of Ruud H. Brakenhoff's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ruud H. Brakenhoff with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ruud H. Brakenhoff more than expected).

Fields of papers citing papers by Ruud H. Brakenhoff

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ruud H. Brakenhoff. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ruud H. Brakenhoff. The network helps show where Ruud H. Brakenhoff may publish in the future.

Co-authorship network of co-authors of Ruud H. Brakenhoff

This figure shows the co-authorship network connecting the top 25 collaborators of Ruud H. Brakenhoff. A scholar is included among the top collaborators of Ruud H. Brakenhoff based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Ruud H. Brakenhoff. Ruud H. Brakenhoff is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Ferroptosis-Related Gene Signatures: Prognostic Role in HPV-Positive Oropharyngeal Squamous Cell Carcinoma 2025 ·Cancers ·(unknown),(unknown),Marta Lucchetta,Stefano Cavalieri,Ruud H. Brakenhoff,(unknown),Kathrin Scheckenbach,Tito Poli,Lisa Licitra,(unknown)	2
2	An Antibody–Drug Conjugate Directed to Tissue Factor Shows Preclinical Antitumor Activity in Head and Neck Cancer as a Single Agent and in Combination with Chemoradiotherapy 2023 ·Molecular Cancer Therapeutics ·Jantine E. Bakema,Marijke Stigter‐van Walsum,Jeffrey R. Harris,(unknown),(unknown),Mischa Houtkamp,Theo S. Plantinga,Elisabeth Bloemena,Ruud H. Brakenhoff,Esther C.W. Breij,Rieneke van de Ven	5
3	Oral leukoplakia classification and staging system with incorporation of differentiated dysplasia 2022 ·Oral Diseases ·(unknown),(unknown),Leon J. Wils,Jos B. Poell,Ruud H. Brakenhoff,Elisabeth Bloemena,(unknown)	11
4	Elucidating the Genetic Landscape of Oral Leukoplakia to Predict Malignant Transformation 2022 ·Clinical Cancer Research ·Leon J. Wils,Jos B. Poell,Arjen Brink,(unknown),(unknown),Jan G.A.M. de Visscher,Elisabeth Bloemena,Ruud H. Brakenhoff	26
5	Associations between clinical and histopathological characteristics in oral leukoplakia 2021 ·Oral Diseases ·(unknown),(unknown),Jos B. Poell,Leon J. Wils,Ruud H. Brakenhoff,Elisabeth Bloemena,Jan G.A.M. de Visscher	14
6	Drug Sensitivity Prediction Models Reveal a Link between DNA Repair Defects and Poor Prognosis in HNSCC 2019 ·Cancer Research ·Paul Essers,(unknown),Caroline V.M. Verhagen,(unknown),Reinout H. de Roest,C. René Leemans,Ruud H. Brakenhoff,Michiel W. M. van den Brekel,Harry Bartelink,Marcel Verheij,Conchita Vens	13
7	Molecular Characterization of Locally Relapsed Head and Neck Cancer after Concomitant Chemoradiotherapy 2019 ·Clinical Cancer Research ·Reinout H. de Roest,Steven W. Mes,Jos B. Poell,Arjen Brink,Mark A. van de Wiel,Elisabeth Bloemena,(unknown),Tito Poli,C. René Leemans,Ruud H. Brakenhoff	17
8	Establishment and Genetic Landscape of Precancer Cell Model Systems from the Head and Neck Mucosal Lining 2018 ·Molecular Cancer Research ·(unknown),Arjen Brink,Marijke Buijze,Marijke Stigter‐van Walsum,Keith D. Hunter,Bauke Ylstra,Elisabeth Bloemena,C. René Leemans,Ruud H. Brakenhoff	24
9	The FA/BRCA Pathway Identified as the Major Predictor of Cisplatin Response in Head and Neck Cancer by Functional Genomics 2016 ·Molecular Cancer Therapeutics ·Sanne R. Martens‐de Kemp,Arjen Brink,(unknown),Renée X. de Menezes,Dennis E. te Beest,C. René Leemans,Victor W. van Beusechem,Boudewijn J.M. Braakhuis,Ruud H. Brakenhoff	22
10	Genome-wide siRNA Screen Identifies the Radiosensitizing Effect of Downregulation of MASTL and FOXM1 in NSCLC 2015 ·Molecular Cancer Therapeutics ·Remco Nagel,Marijke Stigter‐van Walsum,Marijke Buijze,Jaap van den Berg,(unknown),(unknown),Sander R. Piersma,Thang V. Pham,Connie R. Jiménez,Victor W. van Beusechem,Ruud H. Brakenhoff	32
11	Noninvasive Molecular Screening for Oral Precancer in Fanconi Anemia Patients 2015 ·Cancer Prevention Research ·(unknown),Eunike Velleuer,Ralf Dietrich,(unknown),Arjen Brink,Marijke Buijze,Dorly J. H. Deeg,Jean Soulier,C. René Leemans,Boudewijn J.M. Braakhuis,Ruud H. Brakenhoff	15
12	Defects in the Fanconi Anemia Pathway and Chromatid Cohesion in Head and Neck Cancer 2015 ·Cancer Research ·Chantal Stoepker,Najim Ameziane,Petra van der Lelij,Irsan Kooi,Anneke B. Oostra,Martin A. Rooimans,Saskia E. van Mil,Arjen Brink,Ralf Dietrich,Jesper A. Balk,Bauke Ylstra,Hans Joenje,Stephan M. Feller,Ruud H. Brakenhoff	25
13	Identification of Lethal microRNAs Specific for Head and Neck Cancer 2013 ·Clinical Cancer Research ·(unknown),Sanne R. Martens‐de Kemp,Michiel de Maaker,Wessel N. van Wieringen,Bauke Ylstra,Reuven Agami,Francesco Cerisoli,C. René Leemans,Boudewijn J.M. Braakhuis,Ruud H. Brakenhoff	12
14	Functional Genetic Screens Identify Genes Essential for Tumor Cell Survival in Head and Neck and Lung Cancer 2013 ·Clinical Cancer Research ·Sanne R. Martens‐de Kemp,Remco Nagel,Marijke Stigter‐van Walsum,(unknown),Victor W. van Beusechem,Boudewijn J.M. Braakhuis,Ruud H. Brakenhoff	68
15	Prognostic Significance of Truncating TP53 Mutations in Head and Neck Squamous Cell Carcinoma 2011 ·Clinical Cancer Research ·(unknown),Ruud H. Brakenhoff,Dirk J. Kuik,Marijke Buijze,Elisabeth Bloemena,Peter J.F. Snijders,C. René Leemans,Boudewijn J.M. Braakhuis	66
16	To DNA or not to DNA? That Is the Question, When It Comes to Molecular Subtyping for the Clinic! 2011 ·Clinical Cancer Research ·Serge Smeets,Ulrike Harjes,Wessel N. van Wieringen,Daoud Sie,Ruud H. Brakenhoff,Gerrit A. Meijer,Bauke Ylstra	16
17	Differential Proteomics Identifies Protein Biomarkers That Predict Local Relapse of Head and Neck Squamous Cell Carcinomas 2009 ·Clinical Cancer Research ·Tieneke B.M. Schaaij‐Visser,(unknown),Sharon Gauci,Boudewijn J.M. Braakhuis,Marijke Buijze,Albert J. R. Heck,Dirk J. Kuik,Elisabeth Bloemena,C. René Leemans,Monique Slijper,Ruud H. Brakenhoff	61
18	Genomic Profiles Associated with Early Micrometastasis in Lung Cancer: Relevance of 4q Deletion 2009 ·Clinical Cancer Research ·(unknown),Salla Ruosaari,Paul P. Eijk,Jussuf T. Kaifi,Jaakko Hollmén,Emre F. Yekebas,Jakob R. Izbicki,Ruud H. Brakenhoff,Thomas Streichert,Sabine Riethdorf,Markus Glatzel,Bauke Ylstra,Klaus Pantel,Harriet Wikman	72
19	Microarray Analysis of Bleomycin-Exposed Lymphoblastoid Cells for Identifying Cancer Susceptibility Genes 2006 ·Molecular Cancer Research ·Jacqueline Cloos,(unknown),Mireille H.J. Snel,Paul van den IJssel,Bauke Ylstra,C. René Leemans,Ruud H. Brakenhoff,Boudewijn J.M. Braakhuis	28
20	Human Lymphoblastoid Proteome Analysis Reveals a Role for the Inhibitor of Acetyltransferases Complex in DNA Double-Strand Break Response 2006 ·Cancer Research ·(unknown),Jacqueline Cloos,Boudewijn J.M. Braakhuis,Ruud H. Brakenhoff,Albert J. R. Heck,Monique Slijper	12

About Ruud H. Brakenhoff

Ruud H. Brakenhoff is a scholar working on Otorhinolaryngology, Periodontics and Oncology, having authored 242 papers that have together received 15.7k indexed citations. Recurring topics across this work include Head and Neck Cancer Studies (117 papers), Cancer-related Molecular Pathways (41 papers) and Oral Health Pathology and Treatment (31 papers). The work is most often cited by research in Otorhinolaryngology (5.4k citations), Periodontics (1.6k citations) and Cancer Research (3.8k citations). Ruud H. Brakenhoff has collaborated with scholars based in Netherlands, United States and Germany. Frequent co-authors include C. René Leemans, Boudewijn J.M. Braakhuis, Klaus Pantel, Peter J.F. Snijders, Maarten P. Tabor, J. Alain Kummer, Burkhard Brandt, Elisabeth Bloemena, Gordon B. Snow and Chris J.L.M. Meijer. Their work appears in journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Journal of Biological Chemistry.

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