Graeme Scarfe

746 citations

29 papers · 552 indexed · h-index 15

Impact in

Spectroscopy top 5%
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications
Analytical Chemistry top 5%

Papers in

Pharmaceutical Science 6
- Fluorine in Organic Chemistry 3
- Chemical Reactions and Isotopes 3
Pharmacology 5
- Pharmacogenetics and Drug Metabolism 5
- Inflammatory mediators and NSAID effects 3

Co-authors: Jeremy K. Nicholson John C. Lindon Ian D. Wilson Maria Learoyd Venkatesh Pilla Reddy Fadi R. Abou-Shakra José Castro‐Perez Li‐Hong Tseng
Journals: Xenobiotica (7 papers)Drug Metabolism and Disposition (4 papers)Clinical Pharmacology & Therapeutics (3 papers)Analytical Chemistry (2 papers)The Analyst (2 papers)
Partner nations: United Kingdom United States France

In The Last Decade

Graeme Scarfe

29 papers receiving 524 citations

Peers

Countries citing papers authored by Graeme Scarfe

Since Specialization

Citations

This map shows the geographic impact of Graeme Scarfe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Graeme Scarfe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Graeme Scarfe more than expected).

Fields of papers citing papers by Graeme Scarfe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Graeme Scarfe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Graeme Scarfe. The network helps show where Graeme Scarfe may publish in the future.

Co-authors

The 25 scholars most cited alongside Graeme Scarfe, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Graeme Scarfe Line = papers co-authored together Graeme Scarfe links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Recommendations on the Use of Multiple Labels in Human Mass Balance Studies Drug Metabolism and Disposition ·Filip Cuyckens, L Radle, Kenneth C. Cassidy, Douglas K. Spracklin, А Н Науменко, Mette Lund Pedersen, Graeme Scarfe, David S. Wagner, Katrin Georgi, Simone I. Schulz, Hanno Schieferstein, Inga Bjørnsdottir, Andrea A. Romeo, Georges Da Violante, Stefan Blech, Sean A. Hagan, Graeme Young	2024	2
2	A PKPD Case Study: Achieving Clinically Relevant Exposures of AZD5991 in Oncology Mouse Models The AAPS Journal ·Boryana Koseva, mbarretto, Shenghua Wen, Graeme Scarfe, Justin Cidado, Corinne Reimer, Niresh Hariparsad, Rhys D.O. Jones, Lisa Drew, Dermot F. McGinnity, Л.А. Торопов	2023	1
3	Non‐Labeled, Stable Labeled, or Radiolabelled Approaches for Provision of Intravenous Pharmacokinetics in Humans: A Discussion Piece Clinical Pharmacology & Therapeutics ·Graeme Young, Douglas K. Spracklin, А Н Науменко, L Radle, Mette Lund Pedersen, David S. Wagner, Katrin Georgi, Hanno Schieferstein, Inga Bjørnsdottir, Andrea A. Romeo, Kenneth C. Cassidy, Elina N. Nepomnyashchaya, Stefan Blech, Simone I. Schulz, Filip Cuyckens, B. Hnidec, Graeme Scarfe	2023	4
4	Discovery and characterisation of quinazolines and 8-Azaquinazolines as NLRP3 agonists with oral bioavailability in mice Bioorganic & Medicinal Chemistry Letters ·Daniel H. O’Donovan, David Baker, Giovanni Ciotta, Sébastien L. Degorce, Alexander A. Kropotin, Fabiany Sampaio Bertucci Tavares, Leire Escudero‐Ibarz, Lucy Ireland, Yumeng Mao, Martin J. Packer, James Robinson, Graeme Scarfe, Haoran Tang, Viia Valge-Archer	2023	1
5	A Phase 1 Study to Evaluate Absolute Bioavailability and Absorption, Distribution, Metabolism, and Excretion of Savolitinib in Healthy Male Volunteers Clinical Pharmacology in Drug Development ·Mataney Cf, Karthick Vishwanathan, Graeme Scarfe, Yan Li, Marcelo Riccio Facio, Mireille Cantarini, John R. Argue, John Mansell Garrett	2023	3
6	CYP-Mediated Sulfoximine Deimination of AZD6738 Drug Metabolism and Disposition ·Barry Jones, N.S.I. Sahidu, Chungang Gu, Graeme Scarfe	2017	9
7	A Phase I Study to Investigate the Absorption, Pharmacokinetics, and Excretion of [14C]Prucalopride After a Single Oral Dose in Healthy Volunteers Clinical Therapeutics ·Stephen Flach, Graeme Scarfe, Equipe Núcleo Tanque Novo, Jie Ding, Mark Seymour, James D. Blickensdorf, Svitlana ONYSHCHENKO, Steven Troy, Lincoln H. Blumell	2016	12
8	Pharmacokinetics, absorption, and excretion of radiolabeled revexepride: a Phase I clinical trial using a microtracer and accelerator mass spectrometry-based approach Drug Design Development and Therapy ·Stephen Flach, Channarong Naksawadhi, 貴宏八坂, Minhyeong Kang, Svitlana ONYSHCHENKO, James D. Blickensdorf, Graeme Scarfe, Steven Troy, Lincoln H. Blumell	2016	4
9	Virtual Chromatographic Resolution Enhancement in Cryoflow LC−NMR Experiments via Statistical Total Correlation Spectroscopy Analytical Chemistry ·Olivier Cloarec, Alison N. Campbell, Li‐Hong Tseng, Ulrich Braumann, Manfred Spraul, Graeme Scarfe, Richard Weaver, Jeremy K. Nicholson	2007	55
10	THE OLIVACINE DERIVATIVE S 16020 (9-HYDROXY-5,6-DIMETHYL-N-[2-(DIMETHYLAMINO)ETHYL)-6H-PYRIDO(4,3-B)-CARBAZOLE-1-CARBOXAMIDE) INDUCES CYP1A AND ITS OWN METABOLISM IN HUMAN HEPATOCYTES IN PRIMARY CULTURE Drug Metabolism and Disposition ·Lydiane Pichard‐Garcia, Richard Weaver, 兴友徐, Graeme Scarfe, Jean‐Michel Fabre, Catherine Lucas, Patrick Maurel	2004	15
11	Identification of the urinary metabolites of 4-bromoaniline and 4-bromo- [carbonyl - 13 C]-acetanilide in rat Xenobiotica ·Graeme Scarfe, Jeremy K. Nicholson, John C. Lindon, Ian D. Wilson, S. Taylor, E. Clayton, Brian Wright	2002	17
12	Structure-metabolism relationships of substituted anilines: prediction ofN-acetylation andN-oxanilic acid formation using computational chemistry Xenobiotica ·Graeme Scarfe, Ian D. Wilson, Elif BAKSI, Elaine Holmes, Jeremy K. Nicholson, John C. Lindon	2002	12
13	High-Performance Liquid Chromatography Linked to Inductively Coupled Plasma Mass Spectrometry and Orthogonal Acceleration Time-of-Flight Mass Spectrometry for the Simultaneous Detection and Identification of Metabolites of 2-Bromo-4- trifluoromethyl-[¹³C]-acetanilide in Rat Urine Analytical Chemistry ·Jeremy K. Nicholson, John C. Lindon, Graeme Scarfe, Ian D. Wilson, Fadi R. Abou-Shakra, Ashley Sage, José Castro‐Perez	2001	33
14	Identification and quantification of metabolites of 2,3,5,6-tetrafluoro-4-trifluoromethylaniline in rat urine using 19F nuclear magnetic resonance spectroscopy, high-performance liquid chromatography–nuclear magnetic resonance spectroscopy and high-performance liquid chromatography–mass spectrometry Journal of Chromatography B Biomedical Sciences and Applications ·Graeme Scarfe, E. Clayton, Ian D. Wilson, Jeremy K. Nicholson	2000	10
15	High-performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC-ICP-MS) for the analysis of xenobiotic metabolites in rat urine: application to the metabolites of 4-bromoaniline The Analyst ·Jeremy K. Nicholson, John C. Lindon, Graeme Scarfe, Ian D. Wilson, Fadi R. Abou-Shakra, José Castro‐Perez, Andrew N. Eaton, Steve W. Preece	2000	37
16	Investigation of the metabolism of¹⁴C/¹³C-practolol in rat using directly coupled radio-HPLC-NMR-MS Xenobiotica ·Graeme Scarfe, John C. Lindon, Jeremy K. Nicholson, Paul Martín, Brian Wright, S. Taylor, Eva M. Lenz, Ian D. Wilson	2000	7
17	Investigation of the Quantitative Metabolic Fate and Urinary Excretion of 3-Methyl-4-Trifluoromethylaniline and 3-Methyl-4-Trifluoromethylacetanilide in the Rat Drug Metabolism and Disposition ·Graeme Scarfe, John C. Lindon, Jeremy K. Nicholson, Brian Wright, 信也小合, Ian D. Wilson	1999	14
18	Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylaniline in the rat using 19F-NMR spectroscopy and directly coupled HPLCNMR-MS Xenobiotica ·Graeme Scarfe	1999	36
19	¹⁹F-NMR and directly coupled HPLC-NMR-MS investigations into the metabolism of 2-bromo-4- trifluoromethylaniline in rat: a urinary excretion balance study without the use of radiolabelling Xenobiotica ·Graeme Scarfe, Brian Wright, 信也小合, S. Taylor, Ian D. Wilson, John C. Lindon, Jeremy K. Nicholson	1998	44
20	Directly coupled CZE-NMR and CEC-NMR spectroscopy for metabolite analysis: paracetamol metabolites in human urine The Analyst ·Jens Schewitz, Petra Gfrörer, Klaus Pusecker, Li‐Hong Tseng, Klaus Albert, Ernst Bayer, Ian D. Wilson, Nigel J. Bailey, Graeme Scarfe, Jeremy K. Nicholson, John C. Lindon	1998	36

About Graeme Scarfe

Graeme Scarfe is a scholar working on Pharmaceutical Science, Pharmacology, Spectroscopy, Gastroenterology and Pharmacology, having authored 29 papers that have together received 552 indexed citations. Recurring topics across this work include Analytical Chemistry and Chromatography (9 papers), Metabolomics and Mass Spectrometry Studies (6 papers), Pharmacogenetics and Drug Metabolism (5 papers), Fluorine in Organic Chemistry (3 papers), Chemical Reactions and Isotopes (3 papers), Inflammatory mediators and NSAID effects (3 papers), Gastroesophageal reflux and treatments (2 papers) and Cancer, Hypoxia, and Metabolism (2 papers). The work is most often cited by research in Spectroscopy (240 citations), Analytical Chemistry (100 citations), Pharmacology (88 citations), Oncology (107 citations) and Molecular Biology (246 citations). Graeme Scarfe has collaborated with scholars based in United Kingdom, United States and France. Frequent co-authors include Jeremy K. Nicholson, John C. Lindon, Ian D. Wilson, Maria Learoyd, Venkatesh Pilla Reddy, Fadi R. Abou-Shakra, José Castro‐Perez, Li‐Hong Tseng, Brian Wright and S. Taylor. Their work appears in journals such as Xenobiotica, Drug Metabolism and Disposition, Clinical Pharmacology & Therapeutics, Analytical Chemistry and The Analyst.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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