George W. J. Fleet

17.5k citations

452 papers · 14.6k indexed · 4 hit papers · h-index 58

Organic Chemistry top 0.05%
- Carbohydrate Chemistry and Synthesis 318
Biotechnology top 0.1%
Molecular Biology top 0.5%
- Glycosylation and Glycoproteins Research 127
- Chemical Synthesis and Analysis 98
- Enzyme Catalysis and Immobilization 37
Tourism, Leisure and Hospitality Management top 1%
Pharmaceutical Science top 0.5%
- Fluorine in Organic Chemistry 36
Endocrinology, Diabetes and Metabolism
- Diet, Metabolism, and Disease 72
Physiology
- Lysosomal Storage Disorders Research 35
Materials Chemistry
- Enzyme Structure and Function 25

Co-authors: Robert J. Nash Naoki Asano Russell J. Molyneux Atsushi Kato Linda E. Fellows Paul W. Smith Alison A. Watson Mark R. Wormald
Cited by: Organic Chemistry Biotechnology Molecular Biology
Journals: Nature (1 paper)Proceedings of the National Academy of Sciences (2 papers)Journal of Biological Chemistry (1 paper)
Partner nations: United Kingdom Japan United States

In The Last Decade

George W. J. Fleet

446 papers receiving 14.0k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

2003 International Journal of Food Microbiology
2001 Phytochemistry
2000 Tetrahedron Asymmetry
1969 Nature

Peers

Countries citing papers authored by George W. J. Fleet

Since Specialization

Citations

This map shows the geographic impact of George W. J. Fleet's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George W. J. Fleet with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George W. J. Fleet more than expected).

Fields of papers citing papers by George W. J. Fleet

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George W. J. Fleet. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George W. J. Fleet. The network helps show where George W. J. Fleet may publish in the future.

Co-authorship network

The 25 scholars most cited alongside George W. J. Fleet, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with George W. J. Fleet Line = papers co-authored together George W. J. Fleet links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	C-2 fluorinated castanospermines as potent and specific α-glucosidase inhibitors: synthesis and structure–activity relationship study Organic & Biomolecular Chemistry ·Yi‐Xian Li,Min Zhang,Yuna Shimadate,Atsushi Kato,Junzhe Wang,Yue-Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2025	0
2	Synthesis of 8-epi-l-swainsonine, related C6 alkylated derivatives and their α-l-rhamnosidase inhibition Tetrahedron Letters ·Yuna Shimadate,Saki Oshima,Naoto Kasamatsu,Suzuka Yamamoto,Atsumi Taguchi,Robert J. Nash,George W. J. Fleet,Takuya Okada,Naoki Toyooka,Atsushi Kato	2024	1
3	Design and synthesis of iso-allo-DNJ and l-isoDALDP derivatives: pursuit of potent and selective inhibitors of α-glucosidase Organic & Biomolecular Chemistry ·Linfeng Yang,Min Zhang,Yuna Shimadate,Atsushi Kato,Tian‐Yang Liu Hou,Yi‐Xian Li,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2023	0
4	Design, synthesis and glycosidase inhibition of DAB derivatives with C-4 peptide and dipeptide branches Organic & Biomolecular Chemistry ·Dong Zi,Yuna Shimadate,Jun-Zhe Wang,Atsushi Kato,Yi‐Xian Li,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2023	1
5	Design and Pharmacological Chaperone Effects of N-(4′-Phenylbutyl)-DAB Derivatives Targeting the Lipophilic Pocket of Lysosomal Acid α-Glucosidase Journal of Medicinal Chemistry ·Atsushi Kato,Izumi Nakagome,Maki Kise,Kousuke Yoshimura,Nobutada Tanaka,Robert J. Nash,George W. J. Fleet,Yota Kobayashi,Hayato Ikeda,Takuya Okada,Naoki Toyooka	2023	5
6	Introduction of C-alkyl branches to l-iminosugars changes their active site binding orientation Organic & Biomolecular Chemistry ·Atsushi Kato,Izumi Nakagome,Kosuke Yoshimura,Uta Kanekiyo,Mana Kishida,Kenta Shinzawa,Tiantian Lu,Yi‐Xian Li,Robert J. Nash,George W. J. Fleet,Nobutada Tanaka,Chu‐Yi Yu	2022	2
7	Diastereoselective Synthesis, Glycosidase Inhibition, and Docking Study of C-7-Fluorinated Casuarine and Australine Derivatives The Journal of Organic Chemistry ·Yi‐Xian Li,Jun-Zhe Wang,Yuna Shimadate,Maki Kise,Atsushi Kato,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2022	7
8	Stable d -xylose ditriflate in divergent syntheses of dihydroxy prolines, pyrrolidines, tetrahydrofuran-2-carboxylic acids, and cyclic β-amino acids Organic & Biomolecular Chemistry ·Rosalino Balo,Alberto G. Fernández,Adam Chopdat,Soufian El Ayadi,Atsushi Kato,Ramón J. Estévez,George W. J. Fleet,Juan C. Estévez	2022	1
9	Iminosugar Amino Acid idoBR1 Reduces Inflammatory Responses in Microglia Molecules ·Olumayokun A. Olajide,Victoria U. Iwuanyanwu,Owolabi W. Banjo,Atsushi Kato,Yana B. Penkova,George W. J. Fleet,Robert J. Nash	2022	1
10	5-C-Branched Deoxynojirimycin: Strategy for Designing a 1-Deoxynojirimycin-Based Pharmacological Chaperone with a Nanomolar Affinity for Pompe Disease Journal of Medicinal Chemistry ·Atsushi Kato,Izumi Nakagome,Uta Kanekiyo,Tiantian Lu,Yi‐Xian Li,Kosuke Yoshimura,Mana Kishida,Kenta Shinzawa,Tomoki Yoshida,Nobutada Tanaka,Yue‐Mei Jia,Robert J. Nash,George W. J. Fleet,Chu‐Yi Yu	2022	14
11	Azobenzene derivatives show anti-cancer activity against pancreatic cancer cells only under nutrient starvation conditions via G0/G1 cell cycle arrest Tetrahedron ·Kenta Shinzawa,Daiki Kageta,Robert J. Nash,George W. J. Fleet,Tatsushi Imahori,Atsushi Kato	2021	5
12	Stereocomplementary synthesis of casuarine and its 6-epi-, 7-epi-, and 6,7-diepi-stereoisomers Organic & Biomolecular Chemistry ·Yi‐Xian Li,Jun-Zhe Wang,Atsushi Kato,Yuna Shimadate,Maki Kise,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2021	9
13	Iminosugar idoBR1 Isolated from Cucumber Cucumis sativus Reduces Inflammatory Activity ACS Omega ·Robert J. Nash,Barbara Bartholomew,Yana B. Penkova,Dino Rotondo,Fernanda Yamasaka,Graham P. Stafford,Sarah F. Jenkinson,George W. J. Fleet	2020	5
14	Strategy for Designing Selective Lysosomal Acid α-Glucosidase Inhibitors: Binding Orientation and Influence on Selectivity Molecules ·Atsushi Kato,Izumi Nakagome,Mizuki Hata,Robert J. Nash,George W. J. Fleet,Yoshihiro Natori,Yuichi Yoshimura,Isao Adachi,Shuichi Hirono	2020	12
15	Synthesis of Pyrrolidine Monocyclic Analogues of Pochonicine and Its Stereoisomers: Pursuit of Simplified Structures and Potent β-N-Acetylhexosaminidase Inhibition Molecules ·Xin Yan,Yuna Shimadate,Atsushi Kato,Yi‐Xian Li,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2020	5
16	Synthesis and glycosidase inhibition of N-substituted derivatives of 1,4-dideoxy-1,4-imino-d-mannitol (DIM) Organic & Biomolecular Chemistry ·Linfeng Yang,Yuna Shimadate,Atsushi Kato,Yi‐Xian Li,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2019	22
17	Synthesis and Glycosidase Inhibition of Broussonetine M and Its Analogues Molecules ·Qingkun Wu,Kyoko Kinami,Atsushi Kato,Yi‐Xian Li,Yue‐Mei Jia,George W. J. Fleet,Chu‐Yi Yu	2019	11
18	In silicoanalyses of essential interactions of iminosugars with the Hex A active site and evaluation of their pharmacological chaperone effects for Tay–Sachs disease Organic & Biomolecular Chemistry ·Atsushi Kato,Izumi Nakagome,Shinpei Nakagawa,Kyoko Kinami,Isao Adachi,Sarah F. Jenkinson,Jérôme Désiré,Yves Blériot,Robert J. Nash,George W. J. Fleet,Shuichi Hirono	2017	16
19	6‐Deoxyhexoses from l‐Rhamnose in the Search for Inducers of the Rhamnose Operon: Synergy of Chemistry and Biotechnology Chemistry - A European Journal ·Zilei Liu,Akihide Yoshihara,Ciarán L. Kelly,John Heap,Mikkel H. S. Marqvorsen,Sarah F. Jenkinson,Mark R. Wormald,José M. Otero,Amalia M. Estévez,Atsushi Kato,George W. J. Fleet,Ramón J. Estévez,Ken Izumori	2016	9
20	Polyhydroxylated pyrrolidine and pyrrolizidine alkaloids from Hyacinthoides non-scripta and Scilla campanulata Carbohydrate Research ·Atsushi Kato,Isao Adachi,Miwa Miyauchi,Kyoko Ikeda,Tomomi Komae,Haruhisa Kizu,Yukihiko Kameda,Alison A. Watson,Robert J. Nash,Mark R. Wormald,George W. J. Fleet,Naoki Asano	1999	104

About George W. J. Fleet

George W. J. Fleet is a scholar working on Organic Chemistry, Pharmaceutical Science and Endocrinology, Diabetes and Metabolism, having authored 452 papers that have together received 14.6k indexed citations. Recurring topics across this work include Carbohydrate Chemistry and Synthesis (318 papers), Glycosylation and Glycoproteins Research (127 papers), Chemical Synthesis and Analysis (98 papers), Diet, Metabolism, and Disease (72 papers), Enzyme Catalysis and Immobilization (37 papers), Fluorine in Organic Chemistry (36 papers), Lysosomal Storage Disorders Research (35 papers) and Enzyme Structure and Function (25 papers). The work is most often cited by research in Organic Chemistry (11.4k citations), Biotechnology (1.3k citations) and Molecular Biology (8.9k citations). George W. J. Fleet has collaborated with scholars based in United Kingdom, Japan and United States. Frequent co-authors include Robert J. Nash, Naoki Asano, Russell J. Molyneux, Atsushi Kato, Linda E. Fellows, Paul W. Smith, Alison A. Watson, Mark R. Wormald, Sarah F. Jenkinson and Bryan Winchester. Their work appears in journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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