George M. Burslem

4.3k total citations · 3 hit papers
54 papers, 3.2k citations indexed

About

George M. Burslem is a scholar working on Molecular Biology, Organic Chemistry and Oncology. According to data from OpenAlex, George M. Burslem has authored 54 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 43 papers in Molecular Biology, 14 papers in Organic Chemistry and 10 papers in Oncology. Recurrent topics in George M. Burslem's work include Protein Degradation and Inhibitors (18 papers), Ubiquitin and proteasome pathways (13 papers) and Click Chemistry and Applications (11 papers). George M. Burslem is often cited by papers focused on Protein Degradation and Inhibitors (18 papers), Ubiquitin and proteasome pathways (13 papers) and Click Chemistry and Applications (11 papers). George M. Burslem collaborates with scholars based in United States, United Kingdom and France. George M. Burslem's co-authors include Craig M. Crews, Daniel P. Bondeson, John Hines, Saul Jaime‐Figueroa, Blake E. Smith, Jing Wang, Brian D. Hamman, Alexandru D. Buhimschi, Alexey Ishchenko and Andrew J. Wilson and has published in prestigious journals such as Science, Cell and Chemical Reviews.

In The Last Decade

George M. Burslem

48 papers receiving 3.1k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Proteolysis-Targeting Chimeras as Therapeutics and Tools for Biological Discovery

2020 732 citations George M. Burslem, Craig M. Crews profile →
Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead

2017 636 citations Daniel P. Bondeson, George M. Burslem et al. profile →
The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

2017 488 citations George M. Burslem, Daniel P. Bondeson et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
George M. Burslem United States	20	2.8k	1.1k	699	425	128	54	3.2k
Andrew P. Crew United States	21	3.1k 1.1×	1.2k 1.1×	967 1.4×	357 0.8×	66 0.5×	37	3.5k
John Hines United States	24	4.1k 1.5×	1.7k 1.6×	1.2k 1.7×	343 0.8×	82 0.6×	42	4.6k
Kanak Raina United States	14	2.8k 1.0×	996 0.9×	828 1.2×	166 0.4×	65 0.5×	23	3.0k
Saul Jaime‐Figueroa United States	20	2.7k 1.0×	1.2k 1.1×	814 1.2×	480 1.1×	63 0.5×	27	3.2k
Taavi K. Neklesa United States	18	2.0k 0.7×	784 0.7×	380 0.5×	141 0.3×	65 0.5×	25	2.2k
Frank Boschelli United States	28	1.4k 0.5×	581 0.5×	823 1.2×	654 1.5×	70 0.5×	69	2.6k
Stephen K. Tahir United States	22	2.4k 0.9×	980 0.9×	337 0.5×	331 0.8×	86 0.7×	35	3.3k
William C. Shakespeare United States	29	1.8k 0.6×	933 0.8×	666 1.0×	816 1.9×	187 1.5×	59	3.2k
Alexander R. Shoemaker United States	19	2.2k 0.8×	906 0.8×	233 0.3×	332 0.8×	79 0.6×	22	3.0k
Pingda Ren United States	21	2.3k 0.8×	570 0.5×	248 0.4×	636 1.5×	93 0.7×	49	3.2k

Countries citing papers authored by George M. Burslem

Since Specialization

Citations

This map shows the geographic impact of George M. Burslem's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by George M. Burslem with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites George M. Burslem more than expected).

Fields of papers citing papers by George M. Burslem

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by George M. Burslem. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by George M. Burslem. The network helps show where George M. Burslem may publish in the future.

Co-authorship network of co-authors of George M. Burslem

This figure shows the co-authorship network connecting the top 25 collaborators of George M. Burslem. A scholar is included among the top collaborators of George M. Burslem based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with George M. Burslem. George M. Burslem is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Hintzen, Jordi C. J., et al.. (2025). Internally quenched fluorescent peptides provide insights into underexplored and reversible post-translational modifications. Chemical Science. 17(4). 2317–2331.

Burslem, George M., et al.. (2025). Acetylation: a new target for protein degradation in cancer. Trends in cancer. 11(4). 403–420. 1 indexed citations

Bourne, Christopher M., Madhura Kulkarni, Sherry Liu, et al.. (2025). A Potent Inhibitor of Caspase-8 Based on the IL-18 Tetrapeptide Sequence Reveals Shared Specificities between Inflammatory and Apoptotic Initiator Caspases. PubMed. 5(4). 565–581.

Hintzen, Jordi C. J., Mohd Altaf Najar, Takeshi Tsusaka, et al.. (2025). Class I histone deacetylases catalyze lysine lactylation. Journal of Biological Chemistry. 301(10). 110602–110602. 3 indexed citations

Serebrenik, Yevgeniy V., et al.. (2025). Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses. Molecular Cell. 85(9). 1868–1886.e12. 2 indexed citations

Noël, M., et al.. (2024). Sortase mediated protein ubiquitination with defined chain length and topology. RSC Chemical Biology. 5(4). 321–327. 2 indexed citations

Chan, Alexander, Rebecca M. Haley, Mohd Altaf Najar, et al.. (2024). Lipid-mediated intracellular delivery of recombinant bioPROTACs for the rapid degradation of undruggable proteins. Nature Communications. 15(1). 5808–5808. 28 indexed citations

Papadaki, Georgia, et al.. (2023). A Chicken Tapasin ortholog can chaperone empty HLA-B∗37:01 molecules independent of other peptide-loading components. Journal of Biological Chemistry. 299(10). 105136–105136. 2 indexed citations

Sun, Yi, et al.. (2023). Universal open MHC-I molecules for rapid peptide loading and enhanced complex stability across HLA allotypes. Proceedings of the National Academy of Sciences. 120(25). e2304055120–e2304055120. 13 indexed citations

10.

Sun, Yi, et al.. (2023). Xeno interactions between MHC-I proteins and molecular chaperones enable ligand exchange on a broad repertoire of HLA allotypes. Science Advances. 9(8). eade7151–eade7151. 10 indexed citations

11.

Ren, Jian‐Gang, Bowen Xing, Kaosheng Lv, et al.. (2023). RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia. Journal of Clinical Investigation. 133(12). 24 indexed citations

12.

Xu, Kexiang, Swarbhanu Sarkar, Tommy Nguyen, et al.. (2023). Regulation of eDHFR-tagged proteins with trimethoprim PROTACs. Nature Communications. 14(1). 7071–7071. 8 indexed citations

13.

Grasso, Michael, Ye‐Jin Kim, Stefanie D. Boyd, et al.. (2021). The copper chaperone CCS facilitates copper binding to MEK1/2 to promote kinase activation. Journal of Biological Chemistry. 297(6). 101314–101314. 60 indexed citations

14.

Burslem, George M., et al.. (2021). Focused Libraries for Epigenetic Drug Discovery: The Importance of Isosteres. Journal of Medicinal Chemistry. 64(11). 7231–7240. 17 indexed citations

15.

Burslem, George M., Daniel P. Bondeson, & Craig M. Crews. (2020). Scaffold hopping enables direct access to more potent PROTACs with in vivo activity. Chemical Communications. 56(50). 6890–6892. 30 indexed citations

16.

Burslem, George M., Anna Reister Schultz, Daniel P. Bondeson, et al.. (2019). Targeting BCR-ABL1 in Chronic Myeloid Leukemia by PROTAC-Mediated Targeted Protein Degradation. Cancer Research. 79(18). 4744–4753. 165 indexed citations

17.

Grison, Claire M., George M. Burslem, Jennifer A. Miles, et al.. (2017). Double quick, double click reversible peptide “stapling”. Chemical Science. 8(7). 5166–5171. 82 indexed citations

18.

Burslem, George M., Hannah F. Kyle, Adam Nelson, Thomas A. Edwards, & Andrew J. Wilson. (2017). Hypoxia inducible factor (HIF) as a model for studying inhibition of protein–protein interactions. Chemical Science. 8(6). 4188–4202. 31 indexed citations

19.

Burslem, George M. & Craig M. Crews. (2017). Small-Molecule Modulation of Protein Homeostasis. Chemical Reviews. 117(17). 11269–11301. 220 indexed citations

20.

Burslem, George M., Hannah F. Kyle, Alexander L. Breeze, et al.. (2014). Small‐Molecule Proteomimetic Inhibitors of the HIF‐1α–p300 Protein–Protein Interaction. ChemBioChem. 15(8). 1083–1087. 60 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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