Saul Jaime‐Figueroa

4.3k total citations · 5 hit papers
27 papers, 3.2k citations indexed

About

Saul Jaime‐Figueroa is a scholar working on Molecular Biology, Hematology and Organic Chemistry. According to data from OpenAlex, Saul Jaime‐Figueroa has authored 27 papers receiving a total of 3.2k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 9 papers in Hematology and 8 papers in Organic Chemistry. Recurrent topics in Saul Jaime‐Figueroa's work include Protein Degradation and Inhibitors (13 papers), Multiple Myeloma Research and Treatments (9 papers) and Ubiquitin and proteasome pathways (7 papers). Saul Jaime‐Figueroa is often cited by papers focused on Protein Degradation and Inhibitors (13 papers), Multiple Myeloma Research and Treatments (9 papers) and Ubiquitin and proteasome pathways (7 papers). Saul Jaime‐Figueroa collaborates with scholars based in United States, Switzerland and France. Saul Jaime‐Figueroa's co-authors include Craig M. Crews, John Hines, Momar Toure, Jing Wang, Blake E. Smith, Brian D. Hamman, George M. Burslem, Alexandru D. Buhimschi, Daniel P. Bondeson and Alexey Ishchenko and has published in prestigious journals such as Angewandte Chemie International Edition, Nature Communications and Biochemistry.

In The Last Decade

Saul Jaime‐Figueroa

26 papers receiving 3.1k citations

Hit Papers

Lessons in PROTAC Design from Selective Degradation with ... 2015 2026 2018 2022 2017 2015 2017 2019 2018 200 400 600
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead
    2017 636 citations Daniel P. Bondeson, Blake E. Smith et al. Cell chemical biology profile →
  2. Modular PROTAC Design for the Degradation of Oncogenic BCR‐ABL
    2015 492 citations Momar Toure, Doris Hellerschmied et al. Angewandte Chemie International Edition profile →
  3. The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study
    2017 488 citations George M. Burslem, Blake E. Smith et al. Cell chemical biology profile →
  4. Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase
    2019 371 citations Blake E. Smith, Stephen L. Wang et al. Nature Communications profile →
  5. Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation
    2018 298 citations Alexandru D. Buhimschi, Momar Toure et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Saul Jaime‐Figueroa United States 20 2.7k 1.2k 814 480 111 27 3.2k
Momar Toure United States 14 2.0k 0.7× 889 0.7× 658 0.8× 178 0.4× 96 0.9× 18 2.2k
Andrew P. Crew United States 21 3.1k 1.1× 1.2k 1.0× 967 1.2× 357 0.7× 62 0.6× 37 3.5k
George M. Burslem United States 20 2.8k 1.0× 1.1k 0.9× 699 0.9× 425 0.9× 55 0.5× 54 3.2k
Kanak Raina United States 14 2.8k 1.0× 996 0.8× 828 1.0× 166 0.3× 50 0.5× 23 3.0k
Kevin D. Shenk United States 10 1.5k 0.6× 698 0.6× 860 1.1× 128 0.3× 135 1.2× 18 1.9k
Brian E. Cathers United States 17 2.2k 0.8× 619 0.5× 904 1.1× 121 0.3× 143 1.3× 31 2.6k
Angelo Aguilar United States 17 1.3k 0.5× 699 0.6× 195 0.2× 419 0.9× 42 0.4× 28 1.8k
Adam Siddiqui-Jain United States 17 4.2k 1.6× 563 0.5× 157 0.2× 347 0.7× 133 1.2× 41 4.7k
Diane H. Boschelli United States 28 1.2k 0.4× 581 0.5× 452 0.6× 1.4k 2.9× 303 2.7× 87 2.7k
Frank Boschelli United States 28 1.4k 0.5× 581 0.5× 823 1.0× 654 1.4× 579 5.2× 69 2.6k

Countries citing papers authored by Saul Jaime‐Figueroa

Since Specialization
Citations

This map shows the geographic impact of Saul Jaime‐Figueroa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saul Jaime‐Figueroa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saul Jaime‐Figueroa more than expected).

Fields of papers citing papers by Saul Jaime‐Figueroa

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saul Jaime‐Figueroa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saul Jaime‐Figueroa. The network helps show where Saul Jaime‐Figueroa may publish in the future.

Co-authorship network of co-authors of Saul Jaime‐Figueroa

This figure shows the co-authorship network connecting the top 25 collaborators of Saul Jaime‐Figueroa. A scholar is included among the top collaborators of Saul Jaime‐Figueroa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saul Jaime‐Figueroa. Saul Jaime‐Figueroa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Nie, Pengju, et al.. (2024). Development of a Small Molecule Downmodulator for the Transcription Factor Brachyury. Angewandte Chemie International Edition. 63(14). e202316496–e202316496. 1 indexed citations
2.
Samarasinghe, Kusal T. G., Saul Jaime‐Figueroa, Michael Burgess, et al.. (2021). Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras. Cell chemical biology. 28(5). 648–661.e5. 124 indexed citations
3.
Alabi, Shanique, Saul Jaime‐Figueroa, Zhan Yao, et al.. (2021). Mutant-selective degradation by BRAF-targeting PROTACs. Nature Communications. 12(1). 920–920. 105 indexed citations
4.
Jaime‐Figueroa, Saul, Alexandru D. Buhimschi, Momar Toure, John Hines, & Craig M. Crews. (2019). Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties. Bioorganic & Medicinal Chemistry Letters. 30(3). 126877–126877. 73 indexed citations
5.
Smith, Blake E., Stephen L. Wang, Saul Jaime‐Figueroa, et al.. (2019). Differential PROTAC substrate specificity dictated by orientation of recruited E3 ligase. Nature Communications. 10(1). 131–131. 371 indexed citations breakdown →
6.
Burslem, George M., Philipp Ottis, Saul Jaime‐Figueroa, et al.. (2018). Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships. ChemMedChem. 13(15). 1508–1512. 32 indexed citations
7.
Burslem, George M., Blake E. Smith, Saul Jaime‐Figueroa, et al.. (2017). The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study. Cell chemical biology. 25(1). 67–77.e3. 488 indexed citations breakdown →
8.
Bondeson, Daniel P., Blake E. Smith, George M. Burslem, et al.. (2017). Lessons in PROTAC Design from Selective Degradation with a Promiscuous Warhead. Cell chemical biology. 25(1). 78–87.e5. 636 indexed citations breakdown →
9.
Toure, Momar, Saul Jaime‐Figueroa, George M. Burslem, & Craig M. Crews. (2016). Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent. European Journal of Organic Chemistry. 2016(24). 4171–4175. 19 indexed citations
10.
Toure, Momar, Doris Hellerschmied, Saul Jaime‐Figueroa, et al.. (2015). Modular PROTAC Design for the Degradation of Oncogenic BCR‐ABL. Angewandte Chemie International Edition. 55(2). 807–810. 492 indexed citations breakdown →
11.
Toure, Momar, Doris Hellerschmied, Saul Jaime‐Figueroa, et al.. (2015). Modulares PROTAC‐Design zum Abbau von onkogenem BCR‐ABL. Angewandte Chemie. 128(2). 818–821. 23 indexed citations
12.
Jaime‐Figueroa, Saul, Javier de Vicente, Johannes C. Hermann, et al.. (2013). Discovery of a series of novel 5H-pyrrolo[2,3-b]pyrazine-2-phenyl ethers, as potent JAK3 kinase inhibitors. Bioorganic & Medicinal Chemistry Letters. 23(9). 2522–2526. 31 indexed citations
13.
Lynch, Stephen M., Johannes C. Hermann, Saul Jaime‐Figueroa, et al.. (2013). Strategic use of conformational bias and structure based design to identify potent JAK3 inhibitors with improved selectivity against the JAK family and the kinome. Bioorganic & Medicinal Chemistry Letters. 23(9). 2793–2800. 28 indexed citations
14.
Jaime‐Figueroa, Saul, et al.. (2005). Discovery and synthesis of a novel and selective drug-like P2X1 antagonist. Bioorganic & Medicinal Chemistry Letters. 15(13). 3292–3295. 21 indexed citations
15.
López, F., David E. Clarke, Todd R. Elworthy, et al.. (2003). Synthesis, pharmacology and pharmacokinetics of 3-(4-Aryl-piperazin-1-ylalkyl)-uracils as uroselective α1A-antagonists. Bioorganic & Medicinal Chemistry Letters. 13(11). 1873–1878. 11 indexed citations
16.
Jaime‐Figueroa, Saul, et al.. (2001). N-3-ALKYLATION OF URACIL AND DERIVATIVES VIA N-1-BOC PROTECTION. Synthetic Communications. 31(24). 3739–3746. 20 indexed citations
17.
Jaime‐Figueroa, Saul, et al.. (2000). Synthesis and experimental study of through-space hydrogen–fluorine and carbon–fluorine spin–spin coupling in 4,5-substituted 1-acetyl-8-fluoronaphthalenes. Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy. 56(6). 1167–1178. 16 indexed citations
18.
Jaime‐Figueroa, Saul, et al.. (1998). Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines. Tetrahedron Letters. 39(11). 1313–1316. 124 indexed citations
19.
20.
GUZMAN, A., et al.. (1997). Direct N3 Alkylation of Uracil and Derivatives via n1-[2-(trimethylsilyl)ethoxymethyl] Protection. Synlett. 1997(11). 1233–1234. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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