Ganes C. Sen

21.9k citations

245 papers · 17.4k indexed · 4 hit papers · h-index 72

Impact in

Immunology top 0.05%
- interferon and immune responses
- Immune Response and Inflammation
Infectious Diseases top 0.5%
- Viral Infections and Vectors

Papers in

Immunology 131
- interferon and immune responses 113
- Immune Response and Inflammation 31
Molecular Biology 144
- RNA regulation and disease 60
- RNA and protein synthesis mechanisms 38
- RNA Research and Splicing 31

Co-authors: Volker Fensterl Péter Lengyel Saumendra N. Sarkar Saurabh Chattopadhyay George R. Stark Jyotirmoy Kusari Kristi L. Peters Shoudong Li
Journals: Journal of Biological Chemistry (47 papers)Journal of Virology (37 papers)Proceedings of the National Academy of Sciences (17 papers)Journal of Interferon & Cytokine Research (12 papers)Virology (11 papers)
Partner nations: United States Australia Canada

In The Last Decade

Ganes C. Sen

241 papers receiving 16.9k citations

Hit Papers

align trajectories log scale

2′-O methylation of the viral mRNA cap evades host restriction by IFIT family members 2010 · 669 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2010 Nature
2007 Nature Reviews Drug Discovery
2001 Annual Review of Microbiology
1992 Journal of Biological Chemistry

Peers

Countries citing papers authored by Ganes C. Sen

Since Specialization

Citations

This map shows the geographic impact of Ganes C. Sen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ganes C. Sen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ganes C. Sen more than expected).

Fields of papers citing papers by Ganes C. Sen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ganes C. Sen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ganes C. Sen. The network helps show where Ganes C. Sen may publish in the future.

Co-authors

The 25 scholars most cited alongside Ganes C. Sen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ganes C. Sen Line = papers co-authored together Ganes C. Sen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	TLR9 signaling requires ligand-induced phosphorylation of two specific tyrosine residues by EGFR and Syk mBio ·Manoj Veleeparambil, Chenyao Wang, Patricia Kessler, Pracheta Sengupta, Santanu Das, Ritu Chakravarti, Belinda Willard, Ganes C. Sen, Saurabh Chattopadhyay	2025	1
2	IRF3-mediated pathogenicity in a murine model of human hepatitis A PLoS Pathogens ·Lu Sun, You Li, Ichiro Misumi, Olga González‐López, Lucinda Hensley, John M. Cullen, David R. McGivern, Mami Matsuda, Ryosuke Suzuki, Ganes C. Sen, Asuka Hirai-Yuki, Jason K. Whitmire, Stanley M. Lemon	2021	13
3	Ifit2 deficiency restricts microglial activation and leukocyte migration following murine coronavirus (m-CoV) CNS infection PLoS Pathogens ·Jayasri Das Sarma, Amy Burrows, Patricia Rayman, Mihyun Hwang, Soumya Kundu, Nikhil Sharma, Cornelia C. Bergmann, Ganes C. Sen	2020	20
4	PACT-mediated PKR activation acts as a hyperosmotic stress intensity sensor weakening osmoadaptation and enhancing inflammation eLife ·Kenneth T. Farabaugh, Dawid Krokowski, Bo‐Jhih Guan, Zhaofeng Gao, Xing‐Huang Gao, Jing Wu, Raul Jobava, Greeshma Ray, Tristan J de Jesus, Massimiliano G. Bianchi, Evelyn Chukwurah, Ovidio Bussolati, Michael S. Kilberg, David A. Buchner, Ganes C. Sen, Calvin U. Cotton, Christine McDonald, Michelle S. Longworth, Parameswaran Ramakrishnan, Maria Hatzoglou	2020	20
5	Biphasic and cardiomyocyte-specific IFIT activity protects cardiomyocytes from enteroviral infection PLoS Pathogens ·Taishi Kimura, Claudia T. Flynn, Mehrdad Alirezaei, Ganes C. Sen, J. Lindsay Whitton	2019	19
6	A new mechanism of interferon’s antiviral action: Induction of autophagy, essential for paramyxovirus replication, is inhibited by the interferon stimulated gene, TDRD7 PLoS Pathogens ·G. Mani Subramanian, Teodora Kuzmanovic, Ying Zhang, Cara Peter, Manoj Veleeparambil, Ritu Chakravarti, Ganes C. Sen, Saurabh Chattopadhyay	2018	50
7	A Role for Ifit2 in Restricting West Nile Virus Infection in the Brain Journal of Virology ·Hyelim Cho, Bimmi Shrestha, Ganes C. Sen, Michael Diamond	2013	62
8	Evaluation of analytical methods to address Tungsten speciation Global NEST Journal ·Adebayo Ogundipe, Julius Pavlov, Washington Braida, Ganes C. Sen, Gavin O’Connor, (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown), (unknown)	2013	6
9	Epidermal Growth Factor Receptor Is Essential for Toll-Like Receptor 3 Signaling Science Signaling ·M Yamashita, Saurabh Chattopadhyay, Volker Fensterl, Paramananda Saikia, Jaime L. Wetzel, Ganes C. Sen	2012	89
10	Interferons at age 50: past, current and future impact on biomedicine Nature Reviews Drug Discovery ·Ernest C. Borden, Ganes C. Sen, Gilles Uzé, Robert H. Silverman, Richard M. Ransohoff, Graham R. Foster, George R. Stark Hit paper breakdown →	2007	904
11	A role of the double-stranded RNA-binding protein PACT in mouse ear development and hearing Proceedings of the National Academy of Sciences ·Theresa Rowe, Mark D. Rizzi, Keiko Hirose, Gregory A. Peters, Ganes C. Sen	2006	55
12	Requirement of PKR Dimerization Mediated by Specific Hydrophobic Residues for Its Activation by Double-Stranded RNA and Its Antigrowth Effects in Yeast Molecular and Cellular Biology ·Rekha C. Patel, Ganes C. Sen	1998	50
13	Interferon-Stimulated Response Element and NFκB Sites Cooperate to Regulate Double-Stranded RNA-Induced Transcription of the IP-10 Gene Journal of Interferon Research ·CHAOQUN WU, Yoshihiro Ohmori, SUDIP BANDYOPADHYAY, Ganes C. Sen, Thomas A. Hamilton	1994	48
14	PKR: Proposed Nomenclature for the RNA-Dependent Protein Kinase Induced by Interferon Journal of Interferon Research ·Michael J. Clemens, John W.B. Hershey, Ara C. Hovanessian, Bertram C. Jacobs, Michael G. Katze, Randal J. Kaufman, Péter Lengyel, Charles E. Samuel, Ganes C. Sen, Bryan Williams	1993	44
15	Construction and Expression of an Enzymatically Active Human–Mouse Chimeric Double-Stranded RNA-Dependent Protein Kinase Journal of Interferon Research ·Ramesh C. Patel, Ganes C. Sen	1992	4
16	Isolation of cDNA Clones for the Interferon-Induced 67,000-Dalton Protein: Direct Induction of a Family of mRNAs by Human Interferon-α and Interferon-β Journal of Interferon Research ·Henrietta Margolis‐Nunno, Berish Y. Rubin, Sylvia L. Anderson, Ruth M. Lunn, Samar N. Roy, Mark Dizik, Ganes C. Sen	1990	6
17	Interferon-mediated inhibition of retroviral infection: use of a defective retrovirus carrying a drug-resistance gene Virus Research ·Rakesh Kumar, Ganes C. Sen	1989	5
18	Gene Induction by Interferons and Double-Stranded RNA: Selective Inhibition by 2-Aminopurine Molecular and Cellular Biology ·Raj K. Tiwari, Jyotirmoy Kusari, Rakesh Kumar, Ganes C. Sen	1988	42
19	Chromosomal Localization of the Interferon-Inducible Human Gene Encoding mRNA 561 Journal of Interferon Research ·Jyotirmoy Kusari, Paul Szabo, Karl‐Heinz Grzeschik, Ganes C. Sen	1987	8
20	A High-Affinity Monoclonal Antibody (GIF-1) to Human Gamma-interferon: Neutralization of Interferon Mediated Inhibition of Retrovirus Production and 2’-5’ (A) Synthetase Induction Pathobiology ·Carl Feit, Ganes C. Sen, Arie H. Bartal, Yashar Hirshaut, Sylvia L. Anderson, Susan K. Millet, Berish Y. Rubin	1986	1

About Ganes C. Sen

Ganes C. Sen is a scholar working on Immunology, Molecular Biology, Cancer Research, Infectious Diseases and Oncology, having authored 245 papers that have together received 17.4k indexed citations. Recurring topics across this work include interferon and immune responses (113 papers), RNA regulation and disease (60 papers), Cytokine Signaling Pathways and Interactions (40 papers), RNA and protein synthesis mechanisms (38 papers), RNA Research and Splicing (31 papers), Immune Response and Inflammation (31 papers), Viral Infections and Immunology Research (25 papers) and Virus-based gene therapy research (24 papers). The work is most often cited by research in Immunology (9.7k citations), Infectious Diseases (2.6k citations), Virology (637 citations), Oncology (3.1k citations) and Molecular Biology (7.6k citations). Ganes C. Sen has collaborated with scholars based in United States, Australia and Canada. Frequent co-authors include Volker Fensterl, Péter Lengyel, Saumendra N. Sarkar, Saurabh Chattopadhyay, George R. Stark, Jyotirmoy Kusari, Kristi L. Peters, Shoudong Li, Robert H. Silverman and Richard M. Ransohoff. Their work appears in journals such as Journal of Biological Chemistry, Journal of Virology, Proceedings of the National Academy of Sciences, Journal of Interferon & Cytokine Research and Virology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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