Frederic J. Kaye

24.5k citations

130 papers · 14.8k indexed · 3 hit papers · h-index 42

Impact in

Oncology top 0.1%
- Cancer-related Molecular Pathways
- Lung Cancer Research Studies
- HER2/EGFR in Cancer Research
- Colorectal Cancer Treatments and Studies
Pulmonary and Respiratory Medicine top 0.1%
- Lung Cancer Treatments and Mutations

Papers in

Oncology 80
- Cancer-related Molecular Pathways 30
- Lung Cancer Research Studies 14
- Ear and Head Tumors 11
Ophthalmology 12
- Ocular Oncology and Treatments 12

Co-authors: William R. Sellers Bruce E. Johnson Pasi A. Jänne Stacey Gabriel Neal I. Lindeman Katsuhiko Naoki Michael J. Eck Matthew Meyerson
Journals: Oncogene (11 papers)Molecular and Cellular Biology (8 papers)JNCI Journal of the National Cancer Institute (7 papers)Journal of Clinical Oncology (5 papers)Proceedings of the National Academy of Sciences (5 papers)
Partner nations: United States Ukraine United Kingdom

In The Last Decade

Frederic J. Kaye

129 papers receiving 14.4k citations

Hit Papers

align trajectories log scale

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy 2004 · 7.5k citations

Peers

Countries citing papers authored by Frederic J. Kaye

Since Specialization

Citations

This map shows the geographic impact of Frederic J. Kaye's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frederic J. Kaye with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frederic J. Kaye more than expected).

Fields of papers citing papers by Frederic J. Kaye

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frederic J. Kaye. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frederic J. Kaye. The network helps show where Frederic J. Kaye may publish in the future.

Co-authors

The 25 scholars most cited alongside Frederic J. Kaye, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Frederic J. Kaye Line = papers co-authored together Frederic J. Kaye links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	PROTAC-Mediated Dual Degradation of BCL-xL and BCL-2 Is a Highly Effective Therapeutic Strategy in Small-Cell Lung Cancer Cells ·Sajid Khan, Lin Cao, J Wiegand, Peiyi Zhang, Maria Zajac‐Kaye, Frederic J. Kaye, Guangrong Zheng, Daohong Zhou	2024	14
2	Nivolumab monotherapy or combination with ipilimumab with or without cobimetinib in previously treated patients with pancreatic adenocarcinoma (CheckMate 032) Journal for ImmunoTherapy of Cancer ·Margaret K. Callahan, Asim Amin, Frederic J. Kaye, Michael A. Morse, Matthew H. Taylor, Katriina Peltola, Padmanee Sharma, Eileen M. O’Reilly, Анастасия Георгиевна Казначеева, Shaun O’Brien, Marina Tschaika, Dung T. Le	2024	7
3	Disparities Contributing to Late-Stage Diagnosis of Lung, Colorectal, Breast, and Cervical Cancers: Rural and Urban Poverty in Florida Cancers ·Jaclyn Hall, Rahma Mkuu, Shen Cheng-sheng, Jennifer Woodard, Frederic J. Kaye, Jiang Bian, Elizabeth Shenkman, Yi Guo	2023	6
4	Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice Cell Death Discovery ·Sajid Khan, Patrick Kellish, Nick Connis, Dinesh Thummuri, J Wiegand, Peiyi Zhang, Xuan Zhang, Vivekananda Budamagunta, Nan Hua, Yang Yang, Umasankar De, Lingtao Jin, Weizhou Zhang, Guangrong Zheng, Robert Hromas, Christine L. Hann, Maria Zajac‐Kaye, Frederic J. Kaye, Daohong Zhou	2023	31
5	Thymidylate synthase accelerates Men1-mediated pancreatic tumor progression and reduces survival JCI Insight ·Vinod Vijayakurup, Pgdhrm, Hye Seung Lee, Yunjia Hao, Sandra Burkett, Akbar Nawab, Michael W. Dougherty, Christian Jobin, Iqbal Mahmud, Timothy J. Garrett, Michael Feely, Kyoung Bun Lee, Frederic J. Kaye, María V. Guijarro, Maria Zajac‐Kaye	2022	6
6	The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma JCI Insight ·Zirong Chen, Wei Ni, Jian‐Liang Li, Shuibin Lin, Xin Zhou, Yuping Sun, Arkady Koltun, Marino E. Leon, Maria D. Hurtado, Sergei Zolotukhin, Chen Liu, Jianrong Lu, James D. Griffin, Frederic J. Kaye, Lizi Wu	2021	43
7	Targeting Notch and EGFR signaling in human mucoepidermoid carcinoma Signal Transduction and Targeted Therapy ·Wei Ni, Zirong Chen, Xin Zhou, Rongqiang Yang, Екатерина Александровна Сервули, Jianrong Lu, Frederic J. Kaye, Lizi Wu	2021	14
8	CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells Oncogene ·Zirong Chen, Shuibin Lin, Jian‐Liang Li, Wei Ni, Pranay Nirapure, Jianrong Lu, Frederic J. Kaye, Lizi Wu	2018	39
9	Phase 1/2 Study of the CD56-Targeting Antibody-Drug Conjugate Lorvotuzumab Mertansine (IMGN901) in Combination With Carboplatin/Etoposide in Small-Cell Lung Cancer Patients With Extensive-Stage Disease Clinical Lung Cancer ·Mark A. Socinski, Frederic J. Kaye, David R. Spigel, Fred J. Kudrik, Santiago Ponce, Peter Ellis, Margarita Majem, Paul Lorigan, Leena Gandhi, Martin Gutierrez, H. Couvert-Mullot, J. Corral, Luis Paz Ares	2016	67
10	A Sensitive NanoString-Based Assay to Score STK11 (LKB1) Pathway Disruption in Lung Adenocarcinoma Journal of Thoracic Oncology ·Lu Chen, Brienne E. Engel, Eric A. Welsh, Sean Yoder, Stephen G. Brantley, Dung‐Tsa Chen, Amer A. Beg, Chunxia Cao, Frederic J. Kaye, Eric B. Haura, Matthew B. Schabath, W. Douglas Cress	2016	24
11	Role of LKB1-CRTC1 on Glycosylated COX-2 and Response to COX-2 Inhibition in Lung Cancer JNCI Journal of the National Cancer Institute ·Chunxia Cao, Ruli Gao, Min Zhang, Antonio L. Amelio, Mohammad Fallahi, Zirong Chen, Yumei Gu, Chengbin Hu, Eric A. Welsh, Brienne E. Engel, Eric B. Haura, W. Douglas Cress, Lizi Wu, Maria Zajac‐Kaye, Frederic J. Kaye	2014	37
12	hSETD1A Regulates Wnt Target Genes and Controls Tumor Growth of Colorectal Cancer Cells Cancer Research ·Tal Salz, Guangyao Li, Frederic J. Kaye, Lei Zhou, Yi Qiu, Suming Huang	2013	64
13	Aberrantly activated AREG–EGFR signaling is required for the growth and survival of CRTC1–MAML2 fusion-positive mucoepidermoid carcinoma cells Oncogene ·Mingda Huang, Coralie Héloret, Yumei Gu, Chengbin Hu, Jian‐Liang Li, Shuibin Lin, Huangxuan Shen, Judy Kim, Ruli Gao, Pui King Wong, Patrick K. Ha, Frederic J. Kaye, James D. Griffin, Lizi Wu	2013	71
14	DNA Methyltransferase Inhibitor, Zebularine, Delays Tumor Growth and Induces Apoptosis in a Genetically Engineered Mouse Model of Breast Cancer Molecular Cancer Therapeutics ·Min Chen, 池其雄, Akbar Nawab, Sherry X. Yang, Lisa Dyer, Kevin D. Brown, Melinda G. Hollingshead, Kent W. Hunter, Frederic J. Kaye, Steven N. Hochwald, Víctor E. Márquez, Patricia S. Steeg, Maria Zajac‐Kaye	2011	47
15	EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy Science ·J. Guillermo Paez, Pasi A. Jänne, Jeffrey C. Lee, Sean Tracy, Heidi Greulich, Stacey Gabriel, Paula Herman, Frederic J. Kaye, Neal I. Lindeman, Titus J. Boggon, Katsuhiko Naoki, Hidefumi Sasaki, Yoshitaka Fujii, Michael J. Eck, William R. Sellers, Bruce E. Johnson, Matthew Meyerson Hit paper breakdown →	2004	7539
16	t(11;19)(q21;p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway Nature Genetics ·Giovanni Tonon, Cheri Keaggy, Lizi Wu, Akihito Kubo, Amy Coxon, Takefumi Komiya, Kevin O’Neil, Kent J. Kille, Adel K. El‐Naggar, James D. Griffin, Ilan R. Kirsch, Frederic J. Kaye	2003	428
17	Phase II Neoadjuvant Trial of Paclitaxel by 96-Hour Continuous Infusion (CIVI) in Combination With Cisplatin Followed by Chest Radiotherapy for Patients With Stage III Non–Small-Cell Lung Cancer American Journal of Clinical Oncology ·Oscar S. Breathnach, Vijay Kasturi, Frederic J. Kaye, Laurie L. Herscher, G.A Wright, Margaret Edison, Barbara Schüler, Nur Aimi Arazmi, Seth M. Steinberg, K. O’Neil, Bruce E. Johnson	2002	2
18	Disruption of Myc-Tubulin Interaction by Hyperphosphorylation of c-Myc during Mitosis or by Constitutive Hyperphosphorylation of Mutant c-Myc in Burkitt's Lymphoma Molecular and Cellular Biology ·Jacek Nikliński, Gisela Claassen, Weiann Tan, Mark A. Gregory, Carmen J. Allegra, Frederic J. Kaye, Stephan Hann, Maria Zajac‐Kaye	2000	34
19	The N-Terminal Domain of c-Myc Associates with α-Tubulin and Microtubules In Vivo and In Vitro Molecular and Cellular Biology ·Josh Suetterlein, Jacek Nikliński, Valery Bliskovsky, Gregory A. Otterson, 広宣加藤, Frederic J. Kaye, Maria Zajac‐Kaye	1995	80
20	A Randomized Trial Comparing Combination Electron-Beam Radiation and Chemotherapy with Topical Therapy in the Initial Treatment of Mycosis Fungoides New England Journal of Medicine ·Frederic J. Kaye, Paul A. Bunn, Seth M. Steinberg, Ligia Vicent Pacheco, Daniel C. Ihde, A. B. Fischmann, Eli Glatstein, Geraldine P. Schechter, Ruby Phelps, Francine M. Foss, Harry L. Parlette, Michael J. Anderson, Edward A. Sausville	1989	347

About Frederic J. Kaye

Frederic J. Kaye is a scholar working on Oncology, Ophthalmology, Cancer Research, Molecular Biology and Pulmonary and Respiratory Medicine, having authored 130 papers that have together received 14.8k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (30 papers), Lung Cancer Treatments and Mutations (16 papers), Salivary Gland Tumors Diagnosis and Treatment (15 papers), Lung Cancer Research Studies (14 papers), Ubiquitin and proteasome pathways (13 papers), Ocular Oncology and Treatments (12 papers), RNA modifications and cancer (11 papers) and Ear and Head Tumors (11 papers). The work is most often cited by research in Oncology (8.6k citations), Pulmonary and Respiratory Medicine (6.2k citations), Cancer Research (2.8k citations), Molecular Biology (6.6k citations) and Ophthalmology (810 citations). Frederic J. Kaye has collaborated with scholars based in United States, Ukraine and United Kingdom. Frequent co-authors include William R. Sellers, Bruce E. Johnson, Pasi A. Jänne, Stacey Gabriel, Neal I. Lindeman, Katsuhiko Naoki, Michael J. Eck, Matthew Meyerson, Jeffrey C. Lee and Sean Tracy. Their work appears in journals such as Oncogene, Molecular and Cellular Biology, JNCI Journal of the National Cancer Institute, Journal of Clinical Oncology and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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