Frank Miedema

22.9k citations

217 papers · 18.5k indexed · 11 hit papers · h-index 68

Virology top 0.01%
Immunology top 0.05%
Infectious Diseases top 0.05%
Epidemiology top 0.5%
Molecular Biology top 5%

Co-authors: Hanneke Schuitemaker M Tersmette Sigrid A. Otto Dörte Hamann Mette D. Hazenberg Joep M. A. Lange Neeltje A. Kootstra R E de Goede
Topics: HIV Research and Treatment (141 papers)Immune Cell Function and Interaction (105 papers)T-cell and B-cell Immunology (58 papers)
Cited by: Virology Immunology Infectious Diseases
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: Netherlands United States United Kingdom

In The Last Decade

Frank Miedema

215 papers receiving 18.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population

1992 874 citations Hanneke Schuitemaker, Neeltje A. Kootstra et al. Journal of Virology profile →
Programmed Death of T Cells in HIV-1 Infection

1992 804 citations Linde Meyaard, Sigrid A. Otto et al. profile →
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors

2002 792 citations Debbie van Baarle, Frank Miedema et al. profile →
Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule

1992 661 citations Ron A. M. Fouchier, M Groenink et al. Journal of Virology profile →
Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: A composite of redistribution and proliferation

1998 606 citations Frank Miedema et al. profile →
Persistent immune activation in HIV-1 infection is associated with progression to AIDS

2003 577 citations Mette D. Hazenberg, Sigrid A. Otto et al. profile →
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates

1989 555 citations Rob A. Gruters, Joep M. A. Lange et al. Journal of Virology profile →
Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.

1995 548 citations Albert D. M. E. Osterhaus, Hanneke Schuitemaker et al. The Journal of Experimental Medicine profile →
Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex

1988 509 citations Rob A. Gruters, Frank Miedema et al. Journal of Virology profile →
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase

1987 502 citations Rob A. Gruters, Matthijs Tersmette et al. profile →
Assessing scientists for hiring, promotion, and tenure

2018 232 citations Frank Miedema et al. profile →

Peers

Countries citing papers authored by Frank Miedema

Since Specialization

Citations

This map shows the geographic impact of Frank Miedema's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Frank Miedema with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Frank Miedema more than expected).

Fields of papers citing papers by Frank Miedema

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Frank Miedema. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Frank Miedema. The network helps show where Frank Miedema may publish in the future.

Co-authorship network of co-authors of Frank Miedema

This figure shows the co-authorship network connecting the top 25 collaborators of Frank Miedema. A scholar is included among the top collaborators of Frank Miedema based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Frank Miedema. Frank Miedema is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Beyond APC: On the Need for Diamond Open Access Publication Platforms 2020 ·Data Archiving and Networked Services (DANS) ·Frank Miedema,(unknown),(unknown),(unknown),Frans J. Oort	1
2	In vivo Dynamics of Stable Chronic Lymphocytic Leukemia Inversely Correlate with Somatic Hypermutation Levels and Suggest No Major Leukemic Turnover in Bone Marrow 2008 ·Cancer Research ·Rogier van Gent,Arnon P. Kater,Sigrid A. Otto,Annelieke Jaspers,José A. M. Borghans,Nienke Vrisekoop,(unknown),An F.C. Ruiter,Shulamiet Wittebol,Eric Eldering,Marinus H. J. van Oers,Kiki Tesselaar,Marie José Kersten,Frank Miedema	48
3	Restoration of the CD4 T Cell Compartment after Long-Term Highly Active Antiretroviral Therapy without Phenotypical Signs of Accelerated Immunological Aging 2008 ·The Journal of Immunology ·Nienke Vrisekoop,Rogier van Gent,(unknown),Sigrid A. Otto,Jan C.C. Borleffs,Radjin Steingrover,Jan M. Prins,Taco W. Kuijpers,Tom F.W. Wolfs,Sibyl P. M. Geelen,Irma Vulto,Peter M. Lansdorp,Kiki Tesselaar,José A. M. Borghans,Frank Miedema	53
4	Low Immune Activation despite High Levels of Pathogenic Human Immunodeficiency Virus Type 1 Results in Long-Term Asymptomatic Disease 2007 ·Journal of Virology ·Shailesh K. Choudhary,Nienke Vrisekoop,Christine A. Jansen,Sigrid A. Otto,Hanneke Schuitemaker,Frank Miedema,David Camerini	75
5	Intravenous Immunoglobulin (IVIG) Treatment for Modulation of Immune Activation in Human Immunodeficiency Virus Type 1 Infected Therapy-Naive Individuals 2007 ·AIDS Research and Human Retroviruses ·(unknown),Jan M. Prins,Evelien M. Bunnik,C. Erik Hack,Suzanne Jurriaans,Frank Miedema,Joep M. A. Lange,Hanneke Schuitemaker	8
6	Viral Replication Capacity as a Correlate of HLA B57/B5801-Associated Nonprogressive HIV-1 Infection 2007 ·The Journal of Immunology ·Marjon Navis,Ingrid M. M. Schellens,Debbie van Baarle,José A. M. Borghans,Peter van Swieten,Frank Miedema,Neeltje A. Kootstra,Hanneke Schuitemaker	73
7	T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani 2005 ·Clinical Immunology ·Asrat Hailu,Debbie van Baarle,(unknown),Nega Berhe,Frank Miedema,Piet A. Kager	63
8	Short Communication: No Detrimental Immunological Effects of Mycophenolate Mofetil and HAART in Treatment-Naive Acute and Chronic HIV-1-Infected Patients 2005 ·AIDS Research and Human Retroviruses ·Nienke Vrisekoop,(unknown),Christine A. Jansen,Marijke Th. L. Roos,Sigrid A. Otto,Hanneke Schuitemaker,Joep M. A. Lange,Jan M. Prins,Frank Miedema	6
9	Reconstitution of EBV Latent but Not Lytic Antigen-Specific CD4+ and CD8+ T Cells after HIV Treatment with Highly Active Antiretroviral Therapy 2005 ·The Journal of Immunology ·Erwan Piriou,Christine A. Jansen,Karel van Dort,Iris M. De Cuyper,Nening M. Nanlohy,Joep M. A. Lange,Marinus H. J. van Oers,Frank Miedema,Debbie van Baarle	23
10	Natural controlled HIV infection: Preserved HIV-specific immunity despite undetectable replication competent virus 2005 ·Virology ·Nico Kloosterboer,P. H. P. Groeneveld,Christine A. Jansen,(unknown),Frits Koning,(unknown),Ashley J. Duits,Frank Miedema,Debbie van Baarle,Ronald P. van Rij,Kees Brinkman,Hanneke Schuitemaker	24
11	Altered EBV Viral Load Setpoint after HIV Seroconversion Is in Accordance with Lack of Predictive Value of EBV Load for the Occurrence of AIDS-Related Non-Hodgkin Lymphoma 2004 ·The Journal of Immunology ·Erwan Piriou,Karel van Dort,Nening M. Nanlohy,Frank Miedema,M. H. van Oers,Debbie van Baarle	43
12	Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system 2004 ·Immunology Letters ·Debbie van Baarle,Aster Tsegaye,Frank Miedema,Arne N. Akbar	66
13	Absolute Level of Epstein‐Barr Virus DNA in Human Immunodeficiency Virus Type 1 Infection Is Not Predictive of AIDS‐Related Non‐Hodgkin Lymphoma 2002 ·The Journal of Infectious Diseases ·(unknown),Katja C. Wolthers,Egbert Hovenkamp,Hubert G.M. Niesters,Albert D. M. E. Osterhaus,Frank Miedema,Marinus H. J. van Oers	65
14	Selective Decrease in Circulating Vα24+Vβ11+ NKT Cells During HIV Type 1 Infection 2002 ·The Journal of Immunology ·Hans van Vliet,B. Mary E. von Blomberg,Mette D. Hazenberg,Nobusuke Nishi,Sigrid A. Otto,Birgit HB van Benthem,Maria Prins,Frans A.P. Claessen,Alfons J.M. van den Eertwegh,Giuseppe Giaccone,Frank Miedema,Rik J. Scheper,Herbert M. Pinedo	132
15	Programmed Death of T Cells in HIV Infection: Result of Immune Activation? 1995 ·Current topics in microbiology and immunology ·Linde Meyaard,Frank Miedema	7
16	Early Replication Steps but Not Cell Type-Specific Signalling of the Viral Long Terminal Repeat Determine HIV-1 Monocytotropism 1993 ·AIDS Research and Human Retroviruses ·Hanneke Schuitemaker,M Groenink,Linde Meyaard,Neeltje A. Kootstra,Ron A. M. Fouchier,Rob A. Gruters,Han G. Huisman,Matthijs Tersmette,Frank Miedema	13
17	Differential Tropism of Clinical HIV-1 Isolates for Primary Monocytes and Promonocytic Cell Lines 1992 ·AIDS Research and Human Retroviruses ·Hanneke Schuitemaker,Neeltje A. Kootstra,M Groenink,R. E. Y. de Goede,Frank Miedema,Matthijs Tersmette	26
18	Evidence that leukocyte function-associated antigen-1 is involved in recirculation and homing of human lymphocytes via high endothelial venules. 1988 ·The Journal of Immunology ·Steven T. Pals,(unknown),Frank Miedema,Peter Kabel,Gerrit D. Keizer,R.J. Scheper,C J Meijer	102
19	Clonal analysis of functionally distinct human CD4+ T cell subsets. 1988 ·The Journal of Experimental Medicine ·Francien T.M. Rotteveel,(unknown),René A. W. van Lier,Bart C. Kuenen,Anthony Meager,Frank Miedema,C.J. Lucas	82
20	IgG ANTIBODIES TO HTLV-III ASSOCIATED ANTIGENS IN PATIENTS WITH AIDS AND AT RISK FOR AIDS IN THE NETHERLANDS 1983 ·PubMed ·Jaap Goudsmit,(unknown),Peter Kabel,Frank Miedema,Cees J. M. Melief	1

About Frank Miedema

Frank Miedema is a scholar working on Virology, Immunology and Infectious Diseases, having authored 217 papers that have together received 18.5k indexed citations. Recurring topics across this work include HIV Research and Treatment (141 papers), Immune Cell Function and Interaction (105 papers) and T-cell and B-cell Immunology (58 papers). The work is most often cited by research in Virology (12.1k citations), Immunology (10.2k citations) and Infectious Diseases (6.2k citations). Frank Miedema has collaborated with scholars based in Netherlands, United States and United Kingdom. Frequent co-authors include Hanneke Schuitemaker, M Tersmette, Sigrid A. Otto, Dörte Hamann, Mette D. Hazenberg, Joep M. A. Lange, Neeltje A. Kootstra, R E de Goede, Linde Meyaard and Marijke Roos. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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