Mark Helm

18.7k total citations · 7 hit papers
215 papers, 13.1k citations indexed

About

Mark Helm is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Mark Helm has authored 215 papers receiving a total of 13.1k indexed citations (citations by other indexed papers that have themselves been cited), including 204 papers in Molecular Biology, 35 papers in Cancer Research and 15 papers in Oncology. Recurrent topics in Mark Helm's work include RNA modifications and cancer (154 papers), RNA and protein synthesis mechanisms (122 papers) and RNA Research and Splicing (39 papers). Mark Helm is often cited by papers focused on RNA modifications and cancer (154 papers), RNA and protein synthesis mechanisms (122 papers) and RNA Research and Splicing (39 papers). Mark Helm collaborates with scholars based in Germany, France and United States. Mark Helm's co-authors include Yuri Motorin, Frank Lyko, Catherine Florentz, Magdalena A. Machnicka, Elżbieta Purta, Janusz M. Bujnicki, Annika Kötter, Francesca Tuorto, Matthias Schaefer and Stefanie Kellner and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Mark Helm

206 papers receiving 13.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MODOMICS: a database of RNA modification pathways. 2017 update

2017 1.4k citations Annika Kötter, Mark Helm et al. Nucleic Acids Research profile →
MODOMICS: a database of RNA modification pathways—2013 update

2012 825 citations Mark Helm et al. Nucleic Acids Research profile →
RNA methylation by Dnmt2 protects transfer RNAs against stress-induced cleavage

2010 561 citations Katharina Hanna, Francesca Tuorto et al. profile →
Detecting RNA modifications in the epitranscriptome: predict and validate

2017 486 citations Mark Helm, Yuri Motorin Nature Reviews Genetics profile →
Zc3h13/Flacc is required for adenosine methylation by bridging the mRNA-binding factor Rbm15/Spenito to the m⁶A machinery component Wtap/Fl(2)d

2018 463 citations Tina Lenče, Mark Helm et al. profile →
m6A modulates neuronal functions and sex determination in Drosophila

2016 425 citations Tina Lenče, Katharina Schmid et al. Nature profile →
RNA modifications in physiology and disease: towards clinical applications

2023 151 citations Sylvain Delaunay, Mark Helm et al. Nature Reviews Genetics profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Mark Helm Germany	55	12.2k	3.6k	658	601	375	215	13.1k
Tariq M. Rana United States	60	10.9k 0.9×	4.5k 1.2×	984 1.5×	325 0.5×	1.3k 3.4×	172	14.5k
Anthony K. L. Leung United States	40	5.6k 0.5×	1.4k 0.4×	1.5k 2.4×	230 0.4×	866 2.3×	81	7.3k
Susan M. Freier United States	53	14.3k 1.2×	5.8k 1.6×	379 0.6×	130 0.2×	415 1.1×	96	16.1k
Timothy R. Dafforn United Kingdom	50	5.0k 0.4×	1.0k 0.3×	612 0.9×	131 0.2×	379 1.0×	152	7.4k
Matthew D. Disney United States	53	9.5k 0.8×	1.1k 0.3×	321 0.5×	152 0.3×	256 0.7×	193	10.6k
Frédéric H.‐T. Allain Switzerland	65	11.2k 0.9×	930 0.3×	369 0.6×	158 0.3×	417 1.1×	180	12.7k
Mads Bak Denmark	30	3.8k 0.3×	2.2k 0.6×	344 0.5×	191 0.3×	199 0.5×	84	7.4k
Nader Pourmand United States	43	3.4k 0.3×	743 0.2×	283 0.4×	938 1.6×	361 1.0×	111	6.9k
Stephen J. Kron United States	44	5.8k 0.5×	519 0.1×	904 1.4×	254 0.4×	416 1.1×	151	8.4k
Xiaolian Gao United States	39	4.2k 0.3×	1.8k 0.5×	199 0.3×	104 0.2×	297 0.8×	101	5.4k

Countries citing papers authored by Mark Helm

Since Specialization

Citations

This map shows the geographic impact of Mark Helm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Mark Helm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Mark Helm more than expected).

Fields of papers citing papers by Mark Helm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Mark Helm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Mark Helm. The network helps show where Mark Helm may publish in the future.

Co-authorship network of co-authors of Mark Helm

This figure shows the co-authorship network connecting the top 25 collaborators of Mark Helm. A scholar is included among the top collaborators of Mark Helm based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Mark Helm. Mark Helm is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Marchand, Virginie, et al.. (2025). TGT Damages its Substrate tRNAs by the Formation of Abasic Sites in the Anticodon Loop. Journal of Molecular Biology. 437(16). 169000–169000. 2 indexed citations

2.

Voigt, Matthias, Jonathan Schupp, Dirk Schneider, et al.. (2024). Dual Centrifugation‐Based Screening for pH‐Responsive Liposomes. ChemMedChem. 20(1). e202400648–e202400648.

3.

Zimmermann, S., Virginie Marchand, Damien Brégeon, et al.. (2024). Differential redox sensitivity of tRNA dihydrouridylation. Nucleic Acids Research. 52(21). 12784–12797. 4 indexed citations

4.

Marchand, Virginie, et al.. (2024). Selective RNA pseudouridinylation in situ by circular gRNAs in designer organelles. Nature Communications. 15(1). 9177–9177. 2 indexed citations

5.

Pichot, Florian, Virginie Marchand, Mark Helm, & Yuri Motorin. (2023). Data Analysis Pipeline for Detection and Quantification of Pseudouridine (ψ) in RNA by HydraPsiSeq. Methods in molecular biology. 2624. 207–223. 3 indexed citations

6.

Legrand, Carine, Johanna Schott, Daniel Pérez-Hernández, et al.. (2023). Queuosine‐tRNA promotes sex‐dependent learning and memory formation by maintaining codon‐biased translation elongation speed. The EMBO Journal. 42(19). e112507–e112507. 24 indexed citations

7.

Delaunay, Sylvain, Mark Helm, & Michaela Frye. (2023). RNA modifications in physiology and disease: towards clinical applications. Nature Reviews Genetics. 25(2). 104–122. 151 indexed citations breakdown →

8.

Helm, Mark & Yuri Motorin. (2022). Phosphorylation found inside RNA. Nature. 605(7909). 234–235.

9.

Helm, Mark, et al.. (2021). General Principles for the Detection of Modified Nucleotides in RNA by Specific Reagents. Advanced Biology. 5(10). e2100866–e2100866. 20 indexed citations

10.

Fradejas‐Villar, Noelia, Wenchao Zhao, Uwe Reuter, et al.. (2021). The Effect of tRNA[Ser]Sec Isopentenylation on Selenoprotein Expression. International Journal of Molecular Sciences. 22(21). 11454–11454. 11 indexed citations

11.

Motorin, Yuri & Mark Helm. (2021). RNA nucleotide methylation: 2021 update. Wiley Interdisciplinary Reviews - RNA. 13(1). e1691–e1691. 67 indexed citations

12.

Werner, Stephan, Florian Pichot, Virginie Marchand, et al.. (2020). NOseq: amplicon sequencing evaluation method for RNA m6A sites after chemical deamination. Nucleic Acids Research. 49(4). e23–e23. 36 indexed citations

13.

Navarro, Isabela Cunha, Francesca Tuorto, Carine Legrand, et al.. (2020). Translational adaptation to heat stress is mediated by RNA 5‐methylcytosine in Caenorhabditis elegans. The EMBO Journal. 40(6). e105496–e105496. 31 indexed citations

14.

Vilardo, Elisa, Fabian Amman, Ursula Toth, et al.. (2020). Functional characterization of the human tRNA methyltransferases TRMT10A and TRMT10B. Nucleic Acids Research. 48(11). 6157–6169. 46 indexed citations

15.

Meyer, Britta, Steffen Kaiser, Sunny Sharma, et al.. (2019). Identification of the 3-amino-3-carboxypropyl (acp) transferase enzyme responsible for acp3U formation at position 47 in Escherichia coli tRNAs. Nucleic Acids Research. 48(3). 1435–1450. 31 indexed citations

16.

Keller, Patrick, Virginie Marchand, Guillaume Bec, et al.. (2018). Double methylation of tRNA-U54 to 2′-O-methylthymidine (Tm) synergistically decreases immune response by Toll-like receptor 7. Nucleic Acids Research. 46(18). 9764–9775. 23 indexed citations

17.

Marchand, Virginie, Lilia Ayadi, Felix G.M. Ernst, et al.. (2018). AlkAniline‐Seq: Profiling of m⁷G and m³C RNA Modifications at Single Nucleotide Resolution. Angewandte Chemie. 130(51). 17027–17032. 1 indexed citations

18.

Marchand, Virginie, Lilia Ayadi, Felix G.M. Ernst, et al.. (2018). AlkAniline‐Seq: Profiling of m⁷G and m³C RNA Modifications at Single Nucleotide Resolution. Angewandte Chemie International Edition. 57(51). 16785–16790. 141 indexed citations

19.

Werner, Stephan, et al.. (2016). CoverageAnalyzer (CAn): A Tool for Inspection of Modification Signatures in RNA Sequencing Profiles. Biomolecules. 6(4). 42–42. 16 indexed citations

20.

Vogt, Günter, Cassandra Falckenhayn, Anne Schrimpf, et al.. (2015). The marbled crayfish as a paradigm for saltational speciation by autopolyploidy and parthenogenesis in animals. Biology Open. 4(11). 1583–1594. 55 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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